PL1992697T3 - Wytwarzanie TNFR-Fc - Google Patents
Wytwarzanie TNFR-FcInfo
- Publication number
- PL1992697T3 PL1992697T3 PL08005732T PL08005732T PL1992697T3 PL 1992697 T3 PL1992697 T3 PL 1992697T3 PL 08005732 T PL08005732 T PL 08005732T PL 08005732 T PL08005732 T PL 08005732T PL 1992697 T3 PL1992697 T3 PL 1992697T3
- Authority
- PL
- Poland
- Prior art keywords
- tnfr
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/95—Protein-free medium and culture conditions
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60537904P | 2004-08-27 | 2004-08-27 | |
US60537904A | 2004-08-27 | 2004-08-27 | |
EP05791482A EP1781802B1 (en) | 2004-08-27 | 2005-08-26 | Production of a tnfr-ig fusion protein |
EP08005732A EP1992697B1 (en) | 2004-08-27 | 2005-08-26 | Production of TNFR-Fc |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1992697T3 true PL1992697T3 (pl) | 2010-08-31 |
Family
ID=35500648
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL08005732T PL1992697T3 (pl) | 2004-08-27 | 2005-08-26 | Wytwarzanie TNFR-Fc |
PL05791482T PL1781802T3 (pl) | 2004-08-27 | 2005-08-26 | Wytwarzanie białka fuzyjnego TNFR Ig |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL05791482T PL1781802T3 (pl) | 2004-08-27 | 2005-08-26 | Wytwarzanie białka fuzyjnego TNFR Ig |
Country Status (38)
Country | Link |
---|---|
US (1) | US7300773B2 (pl) |
EP (2) | EP1781802B1 (pl) |
JP (3) | JP2008511330A (pl) |
KR (1) | KR100988451B1 (pl) |
CN (2) | CN102876761A (pl) |
AR (2) | AR050537A1 (pl) |
AT (2) | ATE446376T1 (pl) |
AU (1) | AU2005280036B2 (pl) |
BR (1) | BRPI0514694B8 (pl) |
CA (1) | CA2578138C (pl) |
CL (1) | CL2017000577A1 (pl) |
CR (2) | CR8998A (pl) |
CY (2) | CY1109721T1 (pl) |
DE (2) | DE602005020076D1 (pl) |
DK (2) | DK1992697T3 (pl) |
EC (1) | ECSP077354A (pl) |
EG (1) | EG26922A (pl) |
ES (2) | ES2341390T3 (pl) |
GT (2) | GT200500233A (pl) |
HK (2) | HK1121497A1 (pl) |
HN (1) | HN2005000485A (pl) |
HR (2) | HRP20100011T1 (pl) |
IL (1) | IL181588A (pl) |
MX (1) | MX2007002381A (pl) |
MY (1) | MY137803A (pl) |
NO (1) | NO344785B1 (pl) |
NZ (1) | NZ579208A (pl) |
PE (2) | PE20100448A1 (pl) |
PL (2) | PL1992697T3 (pl) |
PT (2) | PT1992697E (pl) |
RS (2) | RS51255B (pl) |
RU (1) | RU2458988C2 (pl) |
SI (2) | SI1992697T1 (pl) |
SV (1) | SV2006002211A (pl) |
TW (1) | TWI364458B (pl) |
UA (1) | UA89383C2 (pl) |
WO (1) | WO2006026447A2 (pl) |
ZA (1) | ZA200701672B (pl) |
Families Citing this family (45)
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TWI374935B (en) | 2004-08-27 | 2012-10-21 | Pfizer Ireland Pharmaceuticals | Production of α-abeta |
TWI384069B (zh) | 2004-08-27 | 2013-02-01 | Pfizer Ireland Pharmaceuticals | 多胜肽之製法 |
BRPI0611901A2 (pt) | 2005-06-14 | 2012-08-28 | Amgen, Inc | composição, liofilizado, kit, e, processo para preparar uma composição |
AR058140A1 (es) * | 2005-10-24 | 2008-01-23 | Wyeth Corp | Metodo de produccion proteica utilizando compuestos anti-senescencia |
US20070231895A1 (en) * | 2005-11-02 | 2007-10-04 | Lee Gene W | Methods for adapting mammalian cells |
ES2668212T3 (es) * | 2006-07-13 | 2018-05-17 | Wyeth Llc | Producción de factor de coagulación IX con patrón de glucosilación mejorado |
CA2666317C (en) * | 2006-11-03 | 2013-08-06 | Wyeth | Glycolysis-inhibiting substances in cell culture |
CA2668771C (en) * | 2006-11-08 | 2016-03-15 | Wyeth | Rationally designed media for cell culture |
RU2009132986A (ru) * | 2007-03-02 | 2011-04-10 | Уайт (Us) | Применение меди и глутамата в культуре клеток для производства полипептидов |
TW200902708A (en) | 2007-04-23 | 2009-01-16 | Wyeth Corp | Methods of protein production using anti-senescence compounds |
DK2154244T3 (en) | 2007-04-26 | 2017-06-12 | Chugai Pharmaceutical Co Ltd | CELL CULTIVATION PROCEDURE WHEN AN ACID-ENRICHED MEDIUM IS USED |
AU2009236187B2 (en) * | 2008-04-17 | 2012-08-02 | Wyeth Llc | Methods for enhanced production of bone morphogenetic proteins |
JP2011516086A (ja) * | 2008-04-18 | 2011-05-26 | 上海中信国健薬業股▲ふん▼有限公司 | 濃縮培養液及びその使用方法 |
US8318416B2 (en) | 2008-08-08 | 2012-11-27 | Biogen Idec Ma Inc. | Nutrient monitoring and feedback control for increased bioproduct production |
LT2464725T (lt) | 2009-08-11 | 2020-06-10 | F. Hoffmann-La Roche Ag | Baltymų gamyba ląstelių mitybinėje terpėje, kurioje nėra glutamino |
IN2012DN05169A (pl) * | 2009-12-02 | 2015-10-23 | Acceleron Pharma Inc | |
CN102858953B (zh) | 2010-04-26 | 2015-09-09 | 诺瓦提斯公司 | 改进的细胞培养基 |
CN107254499B (zh) | 2010-04-26 | 2021-09-17 | 诺华股份有限公司 | 改进的细胞培养方法 |
CA2807607A1 (en) | 2010-08-20 | 2012-02-23 | Wyeth Llc | Cell culture of growth factor-free adapted cells |
US20130331554A1 (en) * | 2010-11-15 | 2013-12-12 | Biogen Idec Inc. | Enrichment and concentration of select product isoforms by overloaded bind and elute chromatography |
ES2560470T3 (es) | 2011-04-29 | 2016-02-19 | Biocon Research Limited | Un método para reducir la heterogeneidad de anticuerpos y un proceso de producción de dichos anticuerpos |
EP2718328A4 (en) | 2011-06-08 | 2014-12-24 | Acceleron Pharma Inc | COMPOSITIONS AND METHODS FOR INCREASING THE HALF TIME OF SERUM |
TW201325606A (zh) | 2011-10-18 | 2013-07-01 | Coherus Biosciences Inc | 用氯化鈉穩定化之依那西普調配物 |
US10493151B2 (en) | 2011-10-18 | 2019-12-03 | Coherus Biosciences, Inc. | Etanercept formulations stabilized with sodium chloride |
SG11201401220SA (en) * | 2011-10-21 | 2014-07-30 | Pfizer | Addition of iron to improve cell culture |
CN104159916A (zh) * | 2012-02-22 | 2014-11-19 | Nvip私人有限公司 | 肿瘤坏死因子受体融合蛋白及其使用方法 |
JP2015525762A (ja) | 2012-07-09 | 2015-09-07 | コヒラス・バイオサイエンシズ・インコーポレイテッド | エタネルセプトの安定な水性製剤 |
CA2882551A1 (en) | 2012-09-11 | 2014-03-20 | Coherus Biosciences, Inc. | Correctly folded etanercept in high purity and excellent yield |
US9217168B2 (en) | 2013-03-14 | 2015-12-22 | Momenta Pharmaceuticals, Inc. | Methods of cell culture |
WO2014160790A1 (en) | 2013-03-26 | 2014-10-02 | Coherus Biosciences, Inc. | Protein production method |
KR101439195B1 (ko) | 2013-04-18 | 2014-09-12 | 동아대학교 산학협력단 | 에셰리키아 콜리 a-53 균주를 이용하여 섬유소 분해효소의 생산성을 향상시키는 공정 |
MX2016004564A (es) * | 2013-10-11 | 2016-07-12 | Regeneron Pharma | Cultivo celular metabolicamente optimizado. |
US11390663B2 (en) | 2013-10-11 | 2022-07-19 | Regeneron Pharmaceuticals, Inc. | Metabolically optimized cell culture |
AU2015210930B2 (en) | 2014-01-30 | 2020-04-30 | Coherus Biosciences, Inc. | Perfusion media |
EP3102589A1 (en) | 2014-02-04 | 2016-12-14 | Biogen MA Inc. | Use of cation-exchange chromatography in the flow-through mode to enrich post-translational modifications |
SG11201704351WA (en) * | 2014-12-01 | 2017-06-29 | Amgen Inc | Process for manipulating the level of glycan content of a glycoprotein |
KR102007930B1 (ko) | 2014-12-31 | 2019-08-06 | 주식회사 엘지화학 | 재조합 당단백질의 글리코실화 조절 방법 |
CN105777897A (zh) * | 2015-03-20 | 2016-07-20 | 广东东阳光药业有限公司 | 一种cho细胞收获液的前处理方法 |
CN107429227B (zh) * | 2015-04-01 | 2022-03-01 | 勃林格殷格翰国际公司 | 细胞培养基 |
KR101936049B1 (ko) * | 2015-10-15 | 2019-01-08 | (주)알테오젠 | IgG Fc 도메인을 가지는 융합 단백질의 생산방법 |
CN114917185B (zh) | 2016-10-21 | 2023-11-14 | 美国安进公司 | 药物配制品及其制备方法 |
CN110484487A (zh) * | 2019-08-21 | 2019-11-22 | 安徽欣乐生物技术有限公司 | 一种适用于cho细胞培养用无蛋白培养基及其培养方法 |
KR20230124578A (ko) | 2020-12-22 | 2023-08-25 | 암젠 인크 | 세포 배양 방법 |
CN115073607A (zh) * | 2021-03-12 | 2022-09-20 | 上海康岱生物医药技术股份有限公司 | Tnfr2与baff受体的融合蛋白 |
CN114480492B (zh) * | 2022-01-28 | 2023-04-21 | 景泽生物医药(合肥)股份有限公司 | 一种重组人抗体融合蛋白的制备方法 |
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TWI384069B (zh) | 2004-08-27 | 2013-02-01 | Pfizer Ireland Pharmaceuticals | 多胜肽之製法 |
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-
2005
- 2005-08-25 TW TW094129077A patent/TWI364458B/zh not_active IP Right Cessation
- 2005-08-25 US US11/213,633 patent/US7300773B2/en active Active
- 2005-08-26 KR KR1020077004810A patent/KR100988451B1/ko active IP Right Grant
- 2005-08-26 EP EP05791482A patent/EP1781802B1/en not_active Revoked
- 2005-08-26 PT PT08005732T patent/PT1992697E/pt unknown
- 2005-08-26 ES ES08005732T patent/ES2341390T3/es active Active
- 2005-08-26 SV SV2005002211A patent/SV2006002211A/es unknown
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