PL1990405T3 - Genetycznie zmodyfikowane szczepy wytwarzające metabolity będące antracyklinami użyteczne jako leki przeciwnowotworowe - Google Patents
Genetycznie zmodyfikowane szczepy wytwarzające metabolity będące antracyklinami użyteczne jako leki przeciwnowotworoweInfo
- Publication number
- PL1990405T3 PL1990405T3 PL07009217T PL07009217T PL1990405T3 PL 1990405 T3 PL1990405 T3 PL 1990405T3 PL 07009217 T PL07009217 T PL 07009217T PL 07009217 T PL07009217 T PL 07009217T PL 1990405 T3 PL1990405 T3 PL 1990405T3
- Authority
- PL
- Poland
- Prior art keywords
- genetically modified
- cancer drugs
- strains producing
- modified strains
- metabolites useful
- Prior art date
Links
- 229940045799 anthracyclines and related substance Drugs 0.000 title 1
- 239000003560 cancer drug Substances 0.000 title 1
- 239000002207 metabolite Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07009217.6A EP1990405B1 (en) | 2007-05-08 | 2007-05-08 | Genetically modified strains producing anthracycline metabolites useful as cancer drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1990405T3 true PL1990405T3 (pl) | 2018-01-31 |
Family
ID=38387557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07009217T PL1990405T3 (pl) | 2007-05-08 | 2007-05-08 | Genetycznie zmodyfikowane szczepy wytwarzające metabolity będące antracyklinami użyteczne jako leki przeciwnowotworowe |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20100143977A1 (pl) |
| EP (1) | EP1990405B1 (pl) |
| JP (1) | JP2010525828A (pl) |
| KR (1) | KR101177175B1 (pl) |
| CN (1) | CN101978043B (pl) |
| CA (1) | CA2687034A1 (pl) |
| DK (1) | DK1990405T3 (pl) |
| ES (1) | ES2644422T3 (pl) |
| MX (1) | MX2009012029A (pl) |
| PL (1) | PL1990405T3 (pl) |
| TW (1) | TWI374187B (pl) |
| WO (1) | WO2008135195A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2301943B1 (en) | 2009-09-08 | 2014-01-08 | Heraeus Precious Metals GmbH & Co. KG | Crystallization of epidaunorubicin x HCI |
| DE102011103751A1 (de) | 2011-05-31 | 2012-12-06 | Heraeus Precious Metals Gmbh & Co. Kg | Kristallisierung von Epirubicinhydrochlorid |
| DE102011111991A1 (de) * | 2011-08-30 | 2013-02-28 | Lead Discovery Center Gmbh | Neue Cyclosporin-Derivate |
| DE102014208194A1 (de) | 2014-04-30 | 2015-11-05 | Heraeus Deutschland GmbH & Co. KG | Aufreinigung von Epidaunorubicin |
| JP6682504B2 (ja) * | 2015-03-30 | 2020-04-15 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | エピルビシンの製造方法およびその新規な製造中間体 |
| CN105861455B (zh) * | 2016-05-16 | 2018-10-26 | 浙江海正药业股份有限公司 | DoxA蛋白突变体及其编码基因与应用 |
| CN107541481B (zh) * | 2016-06-23 | 2021-07-02 | 上海医药工业研究院 | 一种产表阿霉素的基因工程菌及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0024727B1 (en) | 1979-09-01 | 1982-05-26 | FARMITALIA CARLO ERBA S.p.A. | Anthracycline glycosides, processes for their preparation and pharmaceutical composition containing them |
| SI0848009T1 (en) | 1996-12-16 | 2000-12-31 | Pharmachemie B.V. | A process for preparing epirubicin or acid addition salts thereof from daunorubicin |
| US5955319A (en) | 1997-07-28 | 1999-09-21 | Pharmacia & Upjohn, S.P.A. | Process for preparing doxorubicin |
| CA2256318A1 (en) | 1997-03-06 | 1998-09-11 | Pharmacia & Upjohn S.P.A. | Process for preparing doxorubicin |
| US20020012979A1 (en) * | 1998-06-08 | 2002-01-31 | Alan Berry | Vitamin c production in microorganisms and plants |
| FI107053B (fi) | 1998-10-23 | 2001-05-31 | Galilaeus Oy | Nogalamysiinin biosynteesiin liittyvä geeniryhmittymä ja sen käyttö hybridiantibioottien tuotossa |
| DE10300719A1 (de) * | 2003-01-11 | 2004-07-22 | Basf Ag | Verbessertes Verfahren zur Herstellung von Vitamin B12 |
| WO2006111561A1 (en) | 2005-04-21 | 2006-10-26 | Dsm Ip Assets B.V. | Improved microbial production of anthracyclins |
-
2007
- 2007-05-08 PL PL07009217T patent/PL1990405T3/pl unknown
- 2007-05-08 ES ES07009217.6T patent/ES2644422T3/es active Active
- 2007-05-08 DK DK07009217.6T patent/DK1990405T3/da active
- 2007-05-08 EP EP07009217.6A patent/EP1990405B1/en active Active
-
2008
- 2008-04-29 US US12/598,806 patent/US20100143977A1/en not_active Abandoned
- 2008-04-29 CN CN200880015212XA patent/CN101978043B/zh active Active
- 2008-04-29 WO PCT/EP2008/003447 patent/WO2008135195A1/en not_active Ceased
- 2008-04-29 MX MX2009012029A patent/MX2009012029A/es active IP Right Grant
- 2008-04-29 JP JP2010506832A patent/JP2010525828A/ja active Pending
- 2008-04-29 KR KR1020097023289A patent/KR101177175B1/ko active Active
- 2008-04-29 CA CA002687034A patent/CA2687034A1/en not_active Abandoned
- 2008-09-25 TW TW097136944A patent/TWI374187B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2687034A1 (en) | 2008-11-13 |
| DK1990405T3 (da) | 2017-11-06 |
| MX2009012029A (es) | 2010-01-25 |
| TWI374187B (en) | 2012-10-11 |
| US20100143977A1 (en) | 2010-06-10 |
| EP1990405B1 (en) | 2017-07-26 |
| JP2010525828A (ja) | 2010-07-29 |
| EP1990405A1 (en) | 2008-11-12 |
| ES2644422T3 (es) | 2017-11-28 |
| WO2008135195A1 (en) | 2008-11-13 |
| CN101978043A (zh) | 2011-02-16 |
| CN101978043B (zh) | 2013-06-19 |
| KR101177175B1 (ko) | 2012-08-24 |
| KR20100010503A (ko) | 2010-02-01 |
| TW201012923A (en) | 2010-04-01 |
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