PL1846412T3 - Sposób wytwarzania 7-etylo-10-hydroksykamptotecyny - Google Patents

Sposób wytwarzania 7-etylo-10-hydroksykamptotecyny

Info

Publication number
PL1846412T3
PL1846412T3 PL06708893T PL06708893T PL1846412T3 PL 1846412 T3 PL1846412 T3 PL 1846412T3 PL 06708893 T PL06708893 T PL 06708893T PL 06708893 T PL06708893 T PL 06708893T PL 1846412 T3 PL1846412 T3 PL 1846412T3
Authority
PL
Poland
Prior art keywords
ethyl
manufacturing
hydroxy camptothecin
hydroxy
temperature
Prior art date
Application number
PL06708893T
Other languages
English (en)
Inventor
Ilpo Laitinen
Original Assignee
Fermion Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fermion Oy filed Critical Fermion Oy
Publication of PL1846412T3 publication Critical patent/PL1846412T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL06708893T 2005-02-07 2006-02-06 Sposób wytwarzania 7-etylo-10-hydroksykamptotecyny PL1846412T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65017505P 2005-02-07 2005-02-07
EP06708893A EP1846412B1 (en) 2005-02-07 2006-02-06 Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin
PCT/FI2006/000034 WO2006082279A1 (en) 2005-02-07 2006-02-06 Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin

Publications (1)

Publication Number Publication Date
PL1846412T3 true PL1846412T3 (pl) 2010-03-31

Family

ID=36588759

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06708893T PL1846412T3 (pl) 2005-02-07 2006-02-06 Sposób wytwarzania 7-etylo-10-hydroksykamptotecyny

Country Status (9)

Country Link
US (1) US7910737B2 (pl)
EP (1) EP1846412B1 (pl)
JP (1) JP5133705B2 (pl)
AT (1) ATE446299T1 (pl)
CA (1) CA2591081C (pl)
DE (1) DE602006009901D1 (pl)
ES (1) ES2333462T3 (pl)
PL (1) PL1846412T3 (pl)
WO (1) WO2006082279A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1846412T3 (pl) 2005-02-07 2010-03-31 Fermion Oy Sposób wytwarzania 7-etylo-10-hydroksykamptotecyny
CA2591074C (en) * 2005-02-08 2015-01-20 Fermion Oy Preparation method
US7662964B2 (en) * 2005-02-08 2010-02-16 Fermion Oy Process for producing [1,4′] bipiperidinyl-1′-carbonyl chloride or hydrochloride thereof
TWI375678B (en) 2005-06-09 2012-11-01 Yakult Honsha Kk A method of preparation of a tricyclic ketone
ATE460162T1 (de) * 2005-09-20 2010-03-15 Scinopharm Singapore Pte Ltd Neue kristallformen von irinotecan-hydrochlorid
NZ581667A (en) * 2007-06-25 2012-03-30 Scinopharm Taiwan Ltd Crystalline polymorph of 7-ethyl-10-hydroxycamptothecin
WO2012032531A1 (en) * 2010-09-06 2012-03-15 Avra Laboratories Pvt. Ltd. Process for the manufacture of irinotecan hydrochloride by total synthesis
KR101327720B1 (ko) * 2013-02-15 2013-11-11 제일약품주식회사 이리노테칸의 제조방법
CN107428770B (zh) * 2014-10-22 2019-10-01 维瓦西塔斯肿瘤学公司 用于喜树碱类似物合成的方法和体系

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US103309A (en) * 1870-05-24 Improvement in machines for burring wool
US182990A (en) * 1876-10-10 Improvement in corner-finish for rooms
US4473692A (en) * 1981-09-04 1984-09-25 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
JPS6019790A (ja) * 1983-07-14 1985-01-31 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体
US4894456A (en) * 1987-03-31 1990-01-16 Research Triangle Institute Synthesis of camptothecin and analogs thereof
US5053512A (en) * 1987-04-14 1991-10-01 Research Triangle Institute Total synthesis of 20(S) and 20(R)-camptothecin and compthothecin derivatives
TW438775B (en) * 1995-04-07 2001-06-07 Pharmacia & Upjohn Co Llc Novel intermediates and process for the manufacture of camptothecin derivatives (CPT-11) and related compounds
CA2340020A1 (fr) * 1998-08-05 2000-02-17 Aventis Pharma S.A. Utilisation de derives de la camptothecine, avec une toxicite gastro-intestinale reduite
AR035684A1 (es) * 2001-02-21 2004-06-23 Yakult Honsha Kk Procedimiento para preparar 2'-amino-5'-hidroxipropiofenona, uso de la misma para la preparacion de analogos de camptotecina, procedimiento para prepararlos, compuestos intermediarios, procedimiento para preparar una cetona triciclica utilizada en la sintesis de analogos de camptotecina
IL163820A0 (en) 2002-03-01 2005-12-18 Pharmacia Italia Spa Crystalline polymorphic form of irinotecan hydrochloride
WO2003089413A1 (en) * 2002-04-17 2003-10-30 Pharmacia Corporation Pharmacia corporation
US20050267141A1 (en) 2004-05-28 2005-12-01 Phytogen Life Sciences Inc. Process to prepare camptothecin derivatives
WO2006016203A1 (en) 2004-08-09 2006-02-16 Shilpa Medicare Limited An improved process for the preparation of irinotecan hydrochloride trihydrate
PL1846412T3 (pl) 2005-02-07 2010-03-31 Fermion Oy Sposób wytwarzania 7-etylo-10-hydroksykamptotecyny

Also Published As

Publication number Publication date
JP2008529993A (ja) 2008-08-07
US20080103309A1 (en) 2008-05-01
JP5133705B2 (ja) 2013-01-30
CA2591081C (en) 2014-10-28
EP1846412B1 (en) 2009-10-21
EP1846412A1 (en) 2007-10-24
ES2333462T3 (es) 2010-02-22
US7910737B2 (en) 2011-03-22
ATE446299T1 (de) 2009-11-15
DE602006009901D1 (de) 2009-12-03
WO2006082279A1 (en) 2006-08-10
CA2591081A1 (en) 2006-08-10

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