PL1824775T3 - Kompozycja oczyszczająca z bromelainy i sposoby jej wytwarzania - Google Patents

Kompozycja oczyszczająca z bromelainy i sposoby jej wytwarzania

Info

Publication number
PL1824775T3
PL1824775T3 PL05804486T PL05804486T PL1824775T3 PL 1824775 T3 PL1824775 T3 PL 1824775T3 PL 05804486 T PL05804486 T PL 05804486T PL 05804486 T PL05804486 T PL 05804486T PL 1824775 T3 PL1824775 T3 PL 1824775T3
Authority
PL
Poland
Prior art keywords
bromelain
production
methods
debriding composition
debriding
Prior art date
Application number
PL05804486T
Other languages
English (en)
Inventor
Marian Gorecki
Amir Toren
Original Assignee
Mediwound Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediwound Ltd filed Critical Mediwound Ltd
Publication of PL1824775T3 publication Critical patent/PL1824775T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
PL05804486T 2004-11-22 2005-11-22 Kompozycja oczyszczająca z bromelainy i sposoby jej wytwarzania PL1824775T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL16533404A IL165334A0 (en) 2004-11-22 2004-11-22 Debriding composition from bromelain and methods of producing same
EP05804486A EP1824775B1 (en) 2004-11-22 2005-11-22 Debriding composition from bromelain and methods of production thereof
PCT/IL2005/001236 WO2006054309A2 (en) 2004-11-22 2005-11-22 Debriding composition from bromelain

Publications (1)

Publication Number Publication Date
PL1824775T3 true PL1824775T3 (pl) 2012-12-31

Family

ID=36407550

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05804486T PL1824775T3 (pl) 2004-11-22 2005-11-22 Kompozycja oczyszczająca z bromelainy i sposoby jej wytwarzania

Country Status (18)

Country Link
US (2) US8119124B2 (pl)
EP (1) EP1824775B1 (pl)
JP (1) JP5053096B2 (pl)
KR (1) KR101235544B1 (pl)
CN (1) CN101297033B (pl)
AU (1) AU2005305461B2 (pl)
BR (1) BRPI0518050A (pl)
CA (1) CA2587951C (pl)
DK (1) DK1824775T3 (pl)
ES (1) ES2389810T3 (pl)
HK (1) HK1124639A1 (pl)
IL (2) IL165334A0 (pl)
MX (1) MX2007006074A (pl)
NO (1) NO337096B1 (pl)
PL (1) PL1824775T3 (pl)
PT (1) PT1824775E (pl)
WO (1) WO2006054309A2 (pl)
ZA (1) ZA200704821B (pl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE031036T2 (en) * 2010-06-25 2017-06-28 Shire Human Genetic Therapies Therapeutic drug delivery to the central nervous system
BR112013028968A2 (pt) 2011-05-12 2018-04-24 Smith & Nephew Orthopaedics Ag composições de desbridamento de feridas contendo seaprose e métodos de tratamento de feridas utilizando-as
GB201110783D0 (en) 2011-06-24 2011-08-10 Aqua Bio Technology Asa Methods and uses
GB201110777D0 (en) * 2011-06-24 2011-08-10 Aqua Bio Technology Asa Methods and uses
ES2690568T3 (es) 2011-07-20 2018-11-21 Mediwound, Ltd. Extracto proteolítico de bromelaína para el tratamiento de trastornos del tejido conectivo
US10058596B2 (en) * 2011-12-20 2018-08-28 Kci Licensing, Inc. Composition for enzymatic debridement
JP2015523330A (ja) 2012-05-11 2015-08-13 スミス アンド ネフュー インコーポレイテッド 細菌性バイオフィルムを除去するためのセアプローゼの使用
CA2890757C (en) * 2012-11-14 2021-10-26 Smith & Nephew, Inc. Stable thermolysin hydrogel
US10238719B2 (en) 2014-10-10 2019-03-26 Rochal Industries, Llc Compositions and kits for enzymatic debridement and methods of using the same
LT6177B (lt) 2014-10-10 2015-07-27 Uab "Biocentras" Fermentų kompleksų išskyrimas iš steptomyces gougerotii 101, daugiafermentinių biopreparatų ruošimas bei taikymas
US9592280B2 (en) 2014-10-10 2017-03-14 Rochal Industries Llc Compositions and kits for enzymatic debridement and methods of using the same
US20160101166A1 (en) 2014-10-10 2016-04-14 Rochal Industries, Llp Compositions and kits for treating pruritus and methods of using the same
CN104857187A (zh) * 2015-04-28 2015-08-26 李正 一种菠萝蛋白酶烧伤组织愈合药物
WO2017130204A1 (en) * 2016-01-31 2017-08-03 Mediwound Ltd. Debriding composition for treating wounds
US20190142910A1 (en) * 2016-04-18 2019-05-16 Mediwound Ltd Methods of debridement of chronic wounds
EP3490588A1 (en) 2016-07-27 2019-06-05 Smith&Nephew, Inc. Use of thermolysin to reduce or eliminate bacterial biofilms from surfaces
CN107913401A (zh) * 2016-10-08 2018-04-17 江阴市本特塞缪森生命科学研究院有限公司 胰蛋白酶产品及治疗妇科炎症的应用
EP3573622B1 (en) 2017-01-30 2023-10-18 Smith & Nephew, Inc. Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces
US10883084B2 (en) 2018-10-05 2021-01-05 Xenotherapeutics, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same
MX2021003866A (es) 2018-10-05 2021-09-08 Xenotherapeutics Inc Productos y metodos de xenotransplante.
AU2020244827A1 (en) 2019-03-25 2021-09-30 Alexis Bio, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non- human) donor and methods and products relating to same
US20230255880A1 (en) * 2022-02-16 2023-08-17 Guild Associates Inc. Immobilized enzyme-based wound debridement

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4197291A (en) 1974-01-08 1980-04-08 Gerold K. V. Klein Hydrolytic enzyme material
US4226854A (en) 1974-01-08 1980-10-07 Gerold K. V. Klein Debridement of devitalized tissue with hydrolytic enzyme product
US4307081A (en) * 1974-01-08 1981-12-22 Gerold K. V. Klein Enzyme mixture
US4329430A (en) 1979-06-04 1982-05-11 Klein Gerold K V Enzyme mixture
US4320120A (en) 1979-10-22 1982-03-16 Zenyaku Kogyo Kabushiki Kaisha Extracts of Marsdenia cundurango Reichenbach fil
US4361551A (en) 1979-11-05 1982-11-30 Riker Laboratories, Inc. Method of enzymatic debridement
AU543965B2 (en) 1979-11-05 1985-05-09 Riker Laboratories, Inc. Method of enzymatic debridement
US4286064A (en) * 1979-11-05 1981-08-25 Riker Laboratories, Inc. Process for isolating active debriding agent from bromelain
GB8724728D0 (en) 1987-10-22 1987-11-25 Genzyme Corp Cysteine proteinase
CA2046802C (en) 1990-08-15 2007-05-22 Donald Zane Fortney Compositions containing protease produced by vibrio and method of use in debridement and wound healing
AU676464B2 (en) 1991-12-03 1997-03-13 Klein, Margaret L. Proteolytic mixture containing escharase and method of isolating same
IL103969A (en) * 1991-12-03 1997-01-10 Gerold K V Klein Proteolytic mixture containing escharase and method of isolating same
WO1994000147A1 (en) * 1992-06-30 1994-01-06 Cortecs Limited Use of enzymes, especially bromelain, in the treatment of diarrhoea
GB9313188D0 (en) * 1993-06-25 1993-08-11 Cortecs Ltd Medical use of enzymes
US5387517A (en) 1994-03-23 1995-02-07 Ethicon, Inc. Thiol activated protease from stem bromelain for treating devitalized tissue
US5858964A (en) 1995-04-14 1999-01-12 Yeda Research And Development Co. Ltd. Pharmaceutical compositions comprising synthetic peptide copolymer for prevention of GVHD
US5830793A (en) 1995-12-28 1998-11-03 Micron Technology, Inc. Method of selective texfturing for patterned polysilicon electrodes
EP1012305A1 (en) * 1997-02-25 2000-06-28 Cortecs (UK) Limited Component of bromelain
US20020102253A1 (en) * 1997-02-25 2002-08-01 Mynott Tracey Lehanne Component of bromelain
CA2333252C (en) * 1998-07-15 2008-11-25 Ursapharm Arzneimittel Gmbh Use of bromelain proteases for inhibiting blood coagulation
GB9819138D0 (en) * 1998-09-02 1998-10-28 Cortecs Uk Ltd Nucleic acids and proteins from pineapple stem
US20030026794A1 (en) 2001-07-31 2003-02-06 Howard Fein Selective enzyme treatment of skin conditions
WO2003086275A2 (en) 2002-04-15 2003-10-23 Sun Pharmaceutical Industries Limited Preperation of desloratatine
ES2393672T3 (es) 2002-04-23 2012-12-27 Mediwound, Ltd. Aparato y procedimientos para su uso en escarotomía enzimática en síndrome de compartimento inducido por quemaduras
EP2048939A4 (en) * 2006-08-17 2010-04-28 Monsanto Technology Llc TRANSGENIC PLANTS WITH ADVANCED AGRONOMIC CHARACTERISTICS
EP2036978A1 (en) * 2007-09-14 2009-03-18 URSAPHARM Arzneimittel GmbH & Co. KG Recombinant preparation of selected bromelain fractions

Also Published As

Publication number Publication date
EP1824775A2 (en) 2007-08-29
KR101235544B1 (ko) 2013-02-21
DK1824775T3 (da) 2012-09-24
ES2389810T3 (es) 2012-10-31
US8119124B2 (en) 2012-02-21
ZA200704821B (en) 2008-11-26
JP5053096B2 (ja) 2012-10-17
MX2007006074A (es) 2007-10-04
CN101297033B (zh) 2012-05-30
CN101297033A (zh) 2008-10-29
IL165334A0 (en) 2006-01-15
AU2005305461B2 (en) 2011-01-27
AU2005305461A1 (en) 2006-05-26
IL183184A (en) 2015-09-24
IL183184A0 (en) 2007-09-20
EP1824775A4 (en) 2011-01-26
US20090148429A1 (en) 2009-06-11
WO2006054309A2 (en) 2006-05-26
CA2587951A1 (en) 2006-05-26
HK1124639A1 (en) 2009-07-17
WO2006054309A3 (en) 2009-04-30
EP1824775B1 (en) 2012-06-13
US20120171187A1 (en) 2012-07-05
BRPI0518050A (pt) 2008-10-28
NO20073115L (no) 2007-08-13
CA2587951C (en) 2015-03-31
PT1824775E (pt) 2012-09-19
NO337096B1 (no) 2016-01-18
US8540983B2 (en) 2013-09-24
JP2008520651A (ja) 2008-06-19
KR20070091285A (ko) 2007-09-10

Similar Documents

Publication Publication Date Title
HK1124639A1 (en) Debriding composition from bromelain and methods of production thereof
EP1919977A4 (en) POLY (BLOCK-PHOSPHONATO-ESTER) AND POLY (BLOCK-PHOSPHONATO-CARBONATE) AND MANUFACTURING METHOD THEREFOR
EP1879659A4 (en) REIZARING COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF
IL187303A0 (en) Methods of prepering 3 - cyano - quinolines and intermediates made thereby
ZA200702069B (en) Silver-releasing articles and methods of manufacture
ZA200710148B (en) Methods of synthesizing substituted 3-cyanoquinolines and inermediates thereof
IL183017A0 (en) Stabilized ramipril compositions and methods of making
EP1786265A4 (en) NEW COMPOSITIONS AND PROCESSING METHODS
GB0505568D0 (en) Method of manufacture and associated component
HK1109576A1 (en) Aequorin-containing compositions and methods of using same
EP1921054A4 (en) METHOD FOR REINFORCING STONES AND OTHER TREE MATERIALS
GB0520930D0 (en) Composition and method of use
GB0504657D0 (en) Compositions and methods of treatment
EP1802560A4 (en) HALOCOMB STATINE AND METHOD FOR THE PRODUCTION THEREOF
GB0406675D0 (en) Candles and methods of manufacture thereof
EP1791779A4 (en) SURFAX AND METHODS OF MAKING
GB0510483D0 (en) Cement and method of making cement
HU0400586D0 (en) Facing gacaparget and method of producing thereof
AU2004900511A0 (en) Compositions and Methods of Treatment
AU2004904405A0 (en) Compositions and Methods of Treatment
AU2005903854A0 (en) Compositions and methods of treatment
AU2005904259A0 (en) Compositions and methods of treatment
AU2005902426A0 (en) Fertilisers and methods of production
AU2005903621A0 (en) Composite Chute And Methods of Manufacture Thereof
AU2004903329A0 (en) Construction elements and methods of construction