IL165334A0 - Debriding composition from bromelain and methods of producing same - Google Patents

Debriding composition from bromelain and methods of producing same

Info

Publication number
IL165334A0
IL165334A0 IL16533404A IL16533404A IL165334A0 IL 165334 A0 IL165334 A0 IL 165334A0 IL 16533404 A IL16533404 A IL 16533404A IL 16533404 A IL16533404 A IL 16533404A IL 165334 A0 IL165334 A0 IL 165334A0
Authority
IL
Israel
Prior art keywords
bromelain
methods
producing same
debriding composition
debriding
Prior art date
Application number
IL16533404A
Other languages
English (en)
Original Assignee
Mediwound Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediwound Ltd filed Critical Mediwound Ltd
Priority to IL16533404A priority Critical patent/IL165334A0/xx
Priority to CN2005800398592A priority patent/CN101297033B/zh
Priority to ZA200704821A priority patent/ZA200704821B/xx
Priority to PCT/IL2005/001236 priority patent/WO2006054309A2/en
Priority to BRPI0518050-3A priority patent/BRPI0518050A/pt
Priority to EP05804486A priority patent/EP1824775B1/en
Priority to JP2007542509A priority patent/JP5053096B2/ja
Priority to MX2007006074A priority patent/MX2007006074A/es
Priority to DK05804486.8T priority patent/DK1824775T3/da
Priority to CA2587951A priority patent/CA2587951C/en
Priority to PL05804486T priority patent/PL1824775T3/pl
Priority to US11/719,586 priority patent/US8119124B2/en
Priority to AU2005305461A priority patent/AU2005305461B2/en
Priority to KR1020077013257A priority patent/KR101235544B1/ko
Priority to ES05804486T priority patent/ES2389810T3/es
Priority to PT05804486T priority patent/PT1824775E/pt
Publication of IL165334A0 publication Critical patent/IL165334A0/xx
Priority to IL183184A priority patent/IL183184A/en
Priority to NO20073115A priority patent/NO337096B1/no
Priority to HK09103888.0A priority patent/HK1124639A1/xx
Priority to US13/366,954 priority patent/US8540983B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL16533404A 2004-11-22 2004-11-22 Debriding composition from bromelain and methods of producing same IL165334A0 (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
IL16533404A IL165334A0 (en) 2004-11-22 2004-11-22 Debriding composition from bromelain and methods of producing same
CA2587951A CA2587951C (en) 2004-11-22 2005-11-22 Debriding composition from bromelain and methods of production thereof
PL05804486T PL1824775T3 (pl) 2004-11-22 2005-11-22 Kompozycja oczyszczająca z bromelainy i sposoby jej wytwarzania
PCT/IL2005/001236 WO2006054309A2 (en) 2004-11-22 2005-11-22 Debriding composition from bromelain
BRPI0518050-3A BRPI0518050A (pt) 2004-11-22 2005-11-22 composição para debridamento a partir da bromelina e métodos para produção da mesma
EP05804486A EP1824775B1 (en) 2004-11-22 2005-11-22 Debriding composition from bromelain and methods of production thereof
JP2007542509A JP5053096B2 (ja) 2004-11-22 2005-11-22 ブロメラインからの創傷清拭組成物及びその製造方法
MX2007006074A MX2007006074A (es) 2004-11-22 2005-11-22 Composicion de desbridamiento a partir de bromelaina y metodos de produccion de la misma.
DK05804486.8T DK1824775T3 (da) 2004-11-22 2005-11-22 Debrideringssammensætning baseret på bromelain og fremgangsmåder til fremstilling deraf
CN2005800398592A CN101297033B (zh) 2004-11-22 2005-11-22 由菠萝蛋白酶获得的清创组合物及其制备方法
ZA200704821A ZA200704821B (en) 2004-11-22 2005-11-22 Debriding composition from bromelain and methods of production thereof
US11/719,586 US8119124B2 (en) 2004-11-22 2005-11-22 Debriding composition from bromelain and methods of production thereof
AU2005305461A AU2005305461B2 (en) 2004-11-22 2005-11-22 Debriding composition from bromelain and methods of production thereof
KR1020077013257A KR101235544B1 (ko) 2004-11-22 2005-11-22 브로멜라인으로부터 획득된 괴사조직제거 조성물 및 이의생산 방법
ES05804486T ES2389810T3 (es) 2004-11-22 2005-11-22 Composición de desbridamiento a partir de bromelaína y procedimientos de producción de la misma
PT05804486T PT1824775E (pt) 2004-11-22 2005-11-22 Composição de desbridamento a partir de bromelina e métodos de produção da mesma
IL183184A IL183184A (en) 2004-11-22 2007-05-14 Bromaline fresh produce and methods for preparing it
NO20073115A NO337096B1 (no) 2004-11-22 2007-06-18 Debrideringspreparat fra bromelain og fremgangsmåter for fremstilling derav samt anvendelse derav
HK09103888.0A HK1124639A1 (en) 2004-11-22 2009-04-27 Debriding composition from bromelain and methods of production thereof
US13/366,954 US8540983B2 (en) 2004-11-22 2012-02-06 Debriding composition from bromelain and methods of production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL16533404A IL165334A0 (en) 2004-11-22 2004-11-22 Debriding composition from bromelain and methods of producing same

Publications (1)

Publication Number Publication Date
IL165334A0 true IL165334A0 (en) 2006-01-15

Family

ID=36407550

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16533404A IL165334A0 (en) 2004-11-22 2004-11-22 Debriding composition from bromelain and methods of producing same
IL183184A IL183184A (en) 2004-11-22 2007-05-14 Bromaline fresh produce and methods for preparing it

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL183184A IL183184A (en) 2004-11-22 2007-05-14 Bromaline fresh produce and methods for preparing it

Country Status (18)

Country Link
US (2) US8119124B2 (pl)
EP (1) EP1824775B1 (pl)
JP (1) JP5053096B2 (pl)
KR (1) KR101235544B1 (pl)
CN (1) CN101297033B (pl)
AU (1) AU2005305461B2 (pl)
BR (1) BRPI0518050A (pl)
CA (1) CA2587951C (pl)
DK (1) DK1824775T3 (pl)
ES (1) ES2389810T3 (pl)
HK (1) HK1124639A1 (pl)
IL (2) IL165334A0 (pl)
MX (1) MX2007006074A (pl)
NO (1) NO337096B1 (pl)
PL (1) PL1824775T3 (pl)
PT (1) PT1824775E (pl)
WO (1) WO2006054309A2 (pl)
ZA (1) ZA200704821B (pl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2588130T3 (pl) * 2010-06-25 2017-09-29 Shire Human Genetic Therapies, Inc. Dostarczanie środków terapeutycznych do OUN
US20140154235A1 (en) 2011-05-12 2014-06-05 Smith & Nephew Orthopaedics Ag Wound debridement compositions containing seaprose and methods of wound treatment using same
GB201110777D0 (en) * 2011-06-24 2011-08-10 Aqua Bio Technology Asa Methods and uses
GB201110783D0 (en) * 2011-06-24 2011-08-10 Aqua Bio Technology Asa Methods and uses
DK2734216T3 (en) * 2011-07-20 2018-11-19 Mediwound Ltd PROTEOLYTIC EXTRACT FROM BROMELAIN FOR TREATMENT OF CONNECTIVE TISSUE DISEASES
WO2013096337A1 (en) 2011-12-20 2013-06-27 Kci Licensing, Inc. Composition for enzymatic debridement
RU2014145270A (ru) 2012-05-11 2016-07-10 Смит & Невью, Инк. Способ и композиция для разрушения бактериальной биопленки
CN104884079B (zh) * 2012-11-14 2021-02-12 史密夫和内修公司 稳定的嗜热菌蛋白酶水凝胶
US20160101166A1 (en) 2014-10-10 2016-04-14 Rochal Industries, Llp Compositions and kits for treating pruritus and methods of using the same
LT6177B (lt) 2014-10-10 2015-07-27 Uab "Biocentras" Fermentų kompleksų išskyrimas iš steptomyces gougerotii 101, daugiafermentinių biopreparatų ruošimas bei taikymas
US9592280B2 (en) 2014-10-10 2017-03-14 Rochal Industries Llc Compositions and kits for enzymatic debridement and methods of using the same
US10238719B2 (en) 2014-10-10 2019-03-26 Rochal Industries, Llc Compositions and kits for enzymatic debridement and methods of using the same
CN104857187A (zh) * 2015-04-28 2015-08-26 李正 一种菠萝蛋白酶烧伤组织愈合药物
ES2909565T3 (es) * 2016-01-31 2022-05-09 Mediwound Ltd Composición desbridante para el tratamiento de heridas
AU2017252085B2 (en) * 2016-04-18 2021-09-16 Mediwound Ltd Methods of debridement of chronic wounds
CN109475609A (zh) 2016-07-27 2019-03-15 史密夫和内修有限公司 使用嗜热菌蛋白酶减少或消除来自表面的细菌生物膜
CN107913401A (zh) * 2016-10-08 2018-04-17 江阴市本特塞缪森生命科学研究院有限公司 胰蛋白酶产品及治疗妇科炎症的应用
US11413300B2 (en) 2017-01-30 2022-08-16 Smith & Nephew, Inc. Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces
US10883084B2 (en) 2018-10-05 2021-01-05 Xenotherapeutics, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same
WO2020072982A1 (en) 2018-10-05 2020-04-09 Xenotherapeutics, Inc. Xenotransplantation products and methods
EP3945799A1 (en) 2019-03-25 2022-02-09 Xenotherapeutics, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non- human) donor and methods and products relating to same
WO2023159123A1 (en) * 2022-02-16 2023-08-24 Guild Associates Inc. Immobilized enzyme-based wound debridement

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US4197291A (en) 1974-01-08 1980-04-08 Gerold K. V. Klein Hydrolytic enzyme material
US4226854A (en) 1974-01-08 1980-10-07 Gerold K. V. Klein Debridement of devitalized tissue with hydrolytic enzyme product
US4307081A (en) * 1974-01-08 1981-12-22 Gerold K. V. Klein Enzyme mixture
US4329430A (en) * 1979-06-04 1982-05-11 Klein Gerold K V Enzyme mixture
US4320120A (en) 1979-10-22 1982-03-16 Zenyaku Kogyo Kabushiki Kaisha Extracts of Marsdenia cundurango Reichenbach fil
AU543965B2 (en) 1979-11-05 1985-05-09 Riker Laboratories, Inc. Method of enzymatic debridement
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US4286064A (en) 1979-11-05 1981-08-25 Riker Laboratories, Inc. Process for isolating active debriding agent from bromelain
GB8724728D0 (en) 1987-10-22 1987-11-25 Genzyme Corp Cysteine proteinase
CA2046802C (en) 1990-08-15 2007-05-22 Donald Zane Fortney Compositions containing protease produced by vibrio and method of use in debridement and wound healing
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Also Published As

Publication number Publication date
JP5053096B2 (ja) 2012-10-17
MX2007006074A (es) 2007-10-04
IL183184A (en) 2015-09-24
AU2005305461A1 (en) 2006-05-26
CA2587951A1 (en) 2006-05-26
HK1124639A1 (en) 2009-07-17
JP2008520651A (ja) 2008-06-19
ES2389810T3 (es) 2012-10-31
EP1824775A2 (en) 2007-08-29
BRPI0518050A (pt) 2008-10-28
DK1824775T3 (da) 2012-09-24
WO2006054309A2 (en) 2006-05-26
WO2006054309A3 (en) 2009-04-30
US8119124B2 (en) 2012-02-21
CA2587951C (en) 2015-03-31
US20120171187A1 (en) 2012-07-05
PT1824775E (pt) 2012-09-19
PL1824775T3 (pl) 2012-12-31
IL183184A0 (en) 2007-09-20
US20090148429A1 (en) 2009-06-11
AU2005305461B2 (en) 2011-01-27
CN101297033B (zh) 2012-05-30
ZA200704821B (en) 2008-11-26
EP1824775B1 (en) 2012-06-13
US8540983B2 (en) 2013-09-24
NO20073115L (no) 2007-08-13
NO337096B1 (no) 2016-01-18
KR20070091285A (ko) 2007-09-10
EP1824775A4 (en) 2011-01-26
CN101297033A (zh) 2008-10-29
KR101235544B1 (ko) 2013-02-21

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