PL1804804T3 - Kwas 3-[4-dibenzo[b,f][1,4]oksazepin-11-ylo)piperazyn-1-ylo]-2,2-dimetylopropionowy do zastosowania w leczeniu zaburzeń snu - Google Patents
Kwas 3-[4-dibenzo[b,f][1,4]oksazepin-11-ylo)piperazyn-1-ylo]-2,2-dimetylopropionowy do zastosowania w leczeniu zaburzeń snuInfo
- Publication number
- PL1804804T3 PL1804804T3 PL05801120T PL05801120T PL1804804T3 PL 1804804 T3 PL1804804 T3 PL 1804804T3 PL 05801120 T PL05801120 T PL 05801120T PL 05801120 T PL05801120 T PL 05801120T PL 1804804 T3 PL1804804 T3 PL 1804804T3
- Authority
- PL
- Poland
- Prior art keywords
- oxazepin
- dibenzo
- piperazin
- treatment
- propanoic acid
- Prior art date
Links
- UEFWDVMEDFCHGW-UHFFFAOYSA-N 3-(4-benzo[b][1,4]benzoxazepin-6-ylpiperazin-1-yl)-2,2-dimethylpropanoic acid Chemical compound C1CN(CC(C)(C)C(O)=O)CCN1C1=NC2=CC=CC=C2OC2=CC=CC=C12 UEFWDVMEDFCHGW-UHFFFAOYSA-N 0.000 title 1
- 208000019116 sleep disease Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D267/20—[b, f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61184904P | 2004-09-21 | 2004-09-21 | |
| US67319805P | 2005-04-19 | 2005-04-19 | |
| PCT/US2005/034015 WO2006034414A2 (en) | 2004-09-21 | 2005-09-21 | Loxapine analogs and methods of use thereof |
| EP05801120A EP1804804B1 (en) | 2004-09-21 | 2005-09-21 | 3-[4-(DIBENZO[b,f][1,4]OXAZEPIN-11-YL)-PIPERAZIN-1-YL]-2,2-DIMETHYL PROPANOIC ACID FOR USE IN THE TREATMENT OF SLEEP DISORDERS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1804804T3 true PL1804804T3 (pl) | 2012-08-31 |
Family
ID=36090680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05801120T PL1804804T3 (pl) | 2004-09-21 | 2005-09-21 | Kwas 3-[4-dibenzo[b,f][1,4]oksazepin-11-ylo)piperazyn-1-ylo]-2,2-dimetylopropionowy do zastosowania w leczeniu zaburzeń snu |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US20060063755A1 (pl) |
| EP (1) | EP1804804B1 (pl) |
| JP (1) | JP5049129B2 (pl) |
| KR (1) | KR101264444B1 (pl) |
| AT (1) | ATE542536T1 (pl) |
| AU (1) | AU2005286713B2 (pl) |
| BR (1) | BRPI0515518A (pl) |
| CA (1) | CA2580250C (pl) |
| CY (1) | CY1112590T1 (pl) |
| DK (1) | DK1804804T3 (pl) |
| EA (1) | EA012610B1 (pl) |
| ES (1) | ES2378452T3 (pl) |
| MA (1) | MA28985B1 (pl) |
| MX (1) | MX2007003032A (pl) |
| NO (1) | NO20071604L (pl) |
| NZ (1) | NZ553900A (pl) |
| PL (1) | PL1804804T3 (pl) |
| PT (1) | PT1804804E (pl) |
| WO (1) | WO2006034414A2 (pl) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7355042B2 (en) * | 2001-10-16 | 2008-04-08 | Hypnion, Inc. | Treatment of CNS disorders using CNS target modulators |
| US20050085463A1 (en) * | 2003-01-23 | 2005-04-21 | Weiner David M. | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| US20050250767A1 (en) * | 2003-01-23 | 2005-11-10 | Weiner David M | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| JP2006515628A (ja) * | 2003-01-23 | 2006-06-01 | アカディア ファーマシューティカルズ，インコーポレーテッド | ヒト神経精神疾患を処置するためのｎ−デスメチルクロザピンの使用 |
| NZ547911A (en) * | 2003-12-22 | 2010-06-25 | Acadia Pharm Inc | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| US20050282800A1 (en) * | 2004-04-01 | 2005-12-22 | Bo-Ragnar Tolf | Method of synthesis and isolation of solid N-desmethylclozapine and crystalline forms thereof |
| US7563785B2 (en) * | 2004-10-29 | 2009-07-21 | Hypnion, Inc. | Quetiapine analogs and methods of use thereof |
| US20070105836A1 (en) * | 2005-10-31 | 2007-05-10 | Lars Pettersson | Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| US7762006B2 (en) * | 2006-06-14 | 2010-07-27 | Siestamed, Technologies | Medical equipment drying device |
| SI2343286T1 (sl) * | 2006-10-28 | 2015-05-29 | Methylgene Inc. | Derivati dibenzo(b,f)(1,4) oksazepina kot inhibitorji histonske deacetilaze |
| CN103214473A (zh) * | 2007-03-15 | 2013-07-24 | ARYx医疗有限公司 | 二苯并[b,f][1,4]氧杂氮杂*化合物 |
| US9220837B2 (en) | 2007-03-19 | 2015-12-29 | Insuline Medical Ltd. | Method and device for drug delivery |
| US8827979B2 (en) | 2007-03-19 | 2014-09-09 | Insuline Medical Ltd. | Drug delivery device |
| US8622991B2 (en) | 2007-03-19 | 2014-01-07 | Insuline Medical Ltd. | Method and device for drug delivery |
| WO2009081262A1 (en) | 2007-12-18 | 2009-07-02 | Insuline Medical Ltd. | Drug delivery device with sensor for closed-loop operation |
| WO2010052579A2 (en) | 2008-11-07 | 2010-05-14 | Insuline Medical Ltd. | Device and method for drug delivery |
| WO2014116684A1 (en) * | 2013-01-22 | 2014-07-31 | Edward Roberts | Non-peptidic neuropeptide y receptor modulators |
| PL3273952T3 (pl) | 2015-03-26 | 2022-11-14 | SEN-JAM Pharmaceutical LLC | Kombinacja naproksenu i feksofenadyny w celu zahamowania objawów związanych z zatruciem alkoholem |
| JP7696354B2 (ja) * | 2019-10-21 | 2025-06-20 | アライリオン インコーポレイテッド | 睡眠障害の治療のためのＨ１および５－ＨＴ２Ａ受容体調節物質としての３－（４－（１１Ｈ－ジベンゾ［ｂ，ｅ］［１，４］アゼピン－６－イル）ピペラジン－１－イル）－プロパン酸誘導体および３－（４－（ジベンゾ［ｂ，ｆ］［１，４］オキサゼピン／チアゼピン／ジアゼピン－１１－イル）ピペラジン－１－イル）－プロパン酸誘導体 |
| WO2025076527A1 (en) * | 2023-10-07 | 2025-04-10 | Inspire Medical Systems, Inc. | Pulmonary therapy for sleep disordered breathing care |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL140242B (nl) | 1963-03-01 | 1973-11-15 | Wander Ag Dr A | Werkwijze voor het bereiden van op de 11-plaats door een basische groep gesubstitueerde dibenz (b.f.)(1.4) oxazepinen. |
| US3928356A (en) | 1967-10-06 | 1975-12-23 | Fujisawa Pharmaceutical Co | 10-{8 4-({107 -Hydroxy alkyl)-1-piperazimyl{9 -dibenzo (h,f) oxofins and thiepins and acetyl esters thereof |
| NL7110453A (pl) | 1970-08-06 | 1972-02-08 | Wander Ag Dr A | |
| US4072756A (en) | 1973-05-17 | 1978-02-07 | Sandoz Ltd. | Tricyclo piperidino ketones and soporific compositions thereof |
| US4642903A (en) | 1985-03-26 | 1987-02-17 | R. P. Scherer Corporation | Freeze-dried foam dosage form |
| US4855326A (en) | 1987-04-20 | 1989-08-08 | Fuisz Pharmaceutical Ltd. | Rapidly dissoluble medicinal dosage unit and method of manufacture |
| JPH04211071A (ja) | 1990-03-05 | 1992-08-03 | Hokuriku Seiyaku Co Ltd | 多環式化合物 |
| US5578322A (en) | 1990-11-30 | 1996-11-26 | Yamanouchi Pharmaceutical Co., Ltd. | Quick release coated preparation |
| US5518730A (en) | 1992-06-03 | 1996-05-21 | Fuisz Technologies Ltd. | Biodegradable controlled release flash flow melt-spun delivery system |
| US5380473A (en) | 1992-10-23 | 1995-01-10 | Fuisz Technologies Ltd. | Process for making shearform matrix |
| JP3233638B2 (ja) | 1993-07-09 | 2001-11-26 | アール．ピー． シェーラー コーポレイション | 凍結乾燥された薬投与形状物の製造方法 |
| US5616344A (en) | 1994-06-14 | 1997-04-01 | Fuisz Technologies Ltd. | Apparatus and process for strengthening low density compression dosage units and product therefrom |
| US5895664A (en) | 1993-09-10 | 1999-04-20 | Fuisz Technologies Ltd. | Process for forming quickly dispersing comestible unit and product therefrom |
| US5622719A (en) | 1993-09-10 | 1997-04-22 | Fuisz Technologies Ltd. | Process and apparatus for making rapidly dissolving dosage units and product therefrom |
| US5607697A (en) | 1995-06-07 | 1997-03-04 | Cima Labs, Incorporated | Taste masking microparticles for oral dosage forms |
| AR008371A1 (es) | 1996-05-30 | 2000-01-19 | Novartis Ag | Una sal de adicion con acido de una 10-aminoalifatil-dibenz[b,f],oxepina, su empleo; procedimiento para su elaboracion, una 10-aminoalifatil-dibenz[b,f]oxepina, una preparacion farmaceutica que contiene dicha sal o dicha oxepina y un procedimiento para el tratamiento de enfermedades neurodegenerativ |
| WO1998036738A1 (en) | 1997-02-20 | 1998-08-27 | Therics, Inc. | Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same |
| US6277406B1 (en) | 1997-10-08 | 2001-08-21 | Fuisz Technologies Ltd. | Easily processed tablet compositions |
| US7355042B2 (en) | 2001-10-16 | 2008-04-08 | Hypnion, Inc. | Treatment of CNS disorders using CNS target modulators |
| US7189757B2 (en) * | 2001-10-16 | 2007-03-13 | Hypnion, Inc. | Treatment of sleep disorders using CNS target modulators |
| US20050049146A1 (en) | 2001-11-05 | 2005-03-03 | Chiarello John F. | Use of substituted dibenzothiepine derivatives as insecticidal, acaricidal and nematicidal agents |
| EP1578198A1 (en) * | 2002-12-20 | 2005-09-28 | Basf Aktiengesellschaft | Pesticidal dibenzo(hetero)azepine derivatives |
| US20060063754A1 (en) | 2004-09-21 | 2006-03-23 | Edgar Dale M | Methods of treating a sleep disorder |
-
2005
- 2005-09-21 BR BRPI0515518-5A patent/BRPI0515518A/pt not_active IP Right Cessation
- 2005-09-21 DK DK05801120.6T patent/DK1804804T3/da active
- 2005-09-21 PL PL05801120T patent/PL1804804T3/pl unknown
- 2005-09-21 PT PT05801120T patent/PT1804804E/pt unknown
- 2005-09-21 AT AT05801120T patent/ATE542536T1/de active
- 2005-09-21 MX MX2007003032A patent/MX2007003032A/es active IP Right Grant
- 2005-09-21 WO PCT/US2005/034015 patent/WO2006034414A2/en not_active Ceased
- 2005-09-21 AU AU2005286713A patent/AU2005286713B2/en not_active Ceased
- 2005-09-21 EA EA200700702A patent/EA012610B1/ru not_active IP Right Cessation
- 2005-09-21 KR KR1020077009122A patent/KR101264444B1/ko not_active Expired - Fee Related
- 2005-09-21 US US11/232,590 patent/US20060063755A1/en not_active Abandoned
- 2005-09-21 NZ NZ553900A patent/NZ553900A/en not_active IP Right Cessation
- 2005-09-21 JP JP2007532670A patent/JP5049129B2/ja not_active Expired - Fee Related
- 2005-09-21 CA CA2580250A patent/CA2580250C/en not_active Expired - Fee Related
- 2005-09-21 ES ES05801120T patent/ES2378452T3/es not_active Expired - Lifetime
- 2005-09-21 EP EP05801120A patent/EP1804804B1/en not_active Expired - Lifetime
- 2005-09-21 US US11/233,417 patent/US7592333B2/en not_active Expired - Fee Related
-
2007
- 2007-03-20 MA MA29765A patent/MA28985B1/fr unknown
- 2007-03-27 NO NO20071604A patent/NO20071604L/no not_active Application Discontinuation
-
2009
- 2009-03-25 US US12/411,083 patent/US8101596B2/en not_active Expired - Fee Related
-
2012
- 2012-03-28 CY CY20121100315T patent/CY1112590T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ553900A (en) | 2010-10-29 |
| WO2006034414A2 (en) | 2006-03-30 |
| US20060063928A1 (en) | 2006-03-23 |
| NO20071604L (no) | 2007-06-20 |
| KR20070060126A (ko) | 2007-06-12 |
| ATE542536T1 (de) | 2012-02-15 |
| EP1804804A2 (en) | 2007-07-11 |
| EP1804804A4 (en) | 2010-11-24 |
| WO2006034414A3 (en) | 2006-09-08 |
| EP1804804B1 (en) | 2012-01-25 |
| JP2008513510A (ja) | 2008-05-01 |
| US20090186872A1 (en) | 2009-07-23 |
| JP5049129B2 (ja) | 2012-10-17 |
| US20060063755A1 (en) | 2006-03-23 |
| CA2580250A1 (en) | 2006-03-30 |
| KR101264444B1 (ko) | 2013-05-20 |
| DK1804804T3 (da) | 2012-02-20 |
| EA200700702A1 (ru) | 2007-10-26 |
| CA2580250C (en) | 2013-05-14 |
| ES2378452T3 (es) | 2012-04-12 |
| MA28985B1 (fr) | 2007-11-01 |
| CY1112590T1 (el) | 2016-02-10 |
| MX2007003032A (es) | 2007-05-21 |
| AU2005286713A1 (en) | 2006-03-30 |
| EA012610B1 (ru) | 2009-10-30 |
| US8101596B2 (en) | 2012-01-24 |
| US7592333B2 (en) | 2009-09-22 |
| PT1804804E (pt) | 2012-03-30 |
| BRPI0515518A (pt) | 2008-07-29 |
| AU2005286713B2 (en) | 2010-10-28 |
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