PL1740593T3 - Sposoby wytwarzania wodorosiarczanu klopidogrelu w formie polimorficznej I - Google Patents

Sposoby wytwarzania wodorosiarczanu klopidogrelu w formie polimorficznej I

Info

Publication number
PL1740593T3
PL1740593T3 PL05734224.8T PL05734224T PL1740593T3 PL 1740593 T3 PL1740593 T3 PL 1740593T3 PL 05734224 T PL05734224 T PL 05734224T PL 1740593 T3 PL1740593 T3 PL 1740593T3
Authority
PL
Poland
Prior art keywords
processes
preparation
hydrogen sulfate
polymorphic form
clopidogrel hydrogen
Prior art date
Application number
PL05734224.8T
Other languages
English (en)
Inventor
Haifang Mao
Hongguang Qian
Chen Chen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN 200410009028 external-priority patent/CN1690060A/zh
Priority claimed from SI200400122A external-priority patent/SI21749A/sl
Application filed filed Critical
Publication of PL1740593T3 publication Critical patent/PL1740593T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL05734224.8T 2004-04-19 2005-04-19 Sposoby wytwarzania wodorosiarczanu klopidogrelu w formie polimorficznej I PL1740593T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN 200410009028 CN1690060A (zh) 2004-04-19 2004-04-19 一种制备i型硫酸氯吡格雷的方法
SI200400122A SI21749A (sl) 2004-04-21 2004-04-21 Postopek za pripravo polimorfne oblike I klopidogrel hidrogen sulfata

Publications (1)

Publication Number Publication Date
PL1740593T3 true PL1740593T3 (pl) 2016-09-30

Family

ID=34965241

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05734224.8T PL1740593T3 (pl) 2004-04-19 2005-04-19 Sposoby wytwarzania wodorosiarczanu klopidogrelu w formie polimorficznej I

Country Status (10)

Country Link
US (1) US7999106B2 (pl)
EP (1) EP1740593B1 (pl)
EA (1) EA010198B1 (pl)
ES (1) ES2577303T3 (pl)
HR (1) HRP20160757T1 (pl)
HU (1) HUE029459T2 (pl)
NO (1) NO339878B1 (pl)
PL (1) PL1740593T3 (pl)
SI (1) SI1740593T1 (pl)
WO (1) WO2005100364A1 (pl)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7772398B2 (en) * 2005-03-11 2010-08-10 Dr. Reddy's Laboratories, Inc. Process for making crystalline form I of clopidogrel hydrogen sulphate
US20090093635A1 (en) * 2006-03-09 2009-04-09 Sandor Garadnay PROCESS FOR MAKING POLYMORPH FROM I OF (S) - (+) -METHYL-ALPHA- (2-CHLOROPHENYL) -6, 7-DYHIDRO-THIENO- [3, 2-c] PYRIDINE-5 (4H) -ACETATE HYDROGEN SULFATE
US20090247569A1 (en) * 2006-08-03 2009-10-01 Claude Singer Process for Preparing Clopidogrel Bisulphate
WO2008032995A1 (en) * 2006-09-15 2008-03-20 Boryung Pharmaceutical Co., Ltd Clopidogrel(+)-camphorsulfonate salt, method of preparing the same and a pharmaceutical composition comprising the same
SI22383A (sl) * 2006-09-22 2008-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Nov postopek sinteze klopidogrela in nove oblike njegovih farmacevtsko sprejemljivih soli
WO2008068569A2 (en) * 2006-12-01 2008-06-12 Wockhardt Research Centre Processes for the preparation of clopidogrel hydrochloride
EP2114957A4 (en) * 2007-01-29 2011-06-08 Ipca Lab Ltd PROCESS FOR PREPARING CRYSTALLINE CLOPIDOGRAPHYDROGENSULFATE OF FORM I
PL382055A1 (pl) * 2007-03-23 2008-09-29 Koźluk Tomasz Nobilus Ent Sposób wytwarzania formy krystalicznej 1 wodorosiarczanu klopidogrelu
EP2107061A1 (en) 2008-04-02 2009-10-07 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of optically enriched clopidogrel
WO2011042804A2 (en) 2009-10-08 2011-04-14 Jubliant Life Sciences Limited An improved process for the preparation of clopidogrel hydrogen sulfate form i
WO2011051976A2 (en) * 2009-10-30 2011-05-05 Matrix Laboratories Ltd An improved process for the preparation of clopidogrel bisulfate form i
WO2011125069A1 (en) * 2010-03-22 2011-10-13 Rpg Life Sciences Limited A process for preparation of crystalline form i of clopidogrel bisulfate
CN103360406A (zh) * 2012-03-26 2013-10-23 黑龙江福和华星制药集团股份有限公司 一种制备i型硫酸氢氯吡格雷的方法
CN102924474B (zh) * 2012-11-08 2015-04-01 浙江海翔药业股份有限公司 一种氯吡格雷硫酸氢盐晶型ⅰ的制备方法
RS61558B1 (sr) 2013-10-22 2021-04-29 Chiesi Farm Spa Kristalni oblik pde4 inhibitora
HK1249052A1 (zh) 2015-03-06 2018-10-26 BeyondSpring Pharmaceuticals Inc. 治疗与ras突变相关的癌症的方法
KR101710922B1 (ko) 2015-06-03 2017-02-28 경동제약 주식회사 클로피도그렐 황산염 결정형 i형의 제조방법
NZ739044A (en) 2015-06-17 2022-08-26 Otsuka America Pharmaceutical Inc Crystalline compounds
MX376122B (es) 2015-07-13 2025-03-07 Beyondspring Pharmaceuticals Inc Composiciones de plinabulina.
SG11201806583XA (en) 2016-02-08 2018-09-27 Beyondspring Pharmaceuticals Inc Compositions containing tucaresol or its analogs
BR112018074990A2 (pt) 2016-06-06 2019-03-12 Beyondspring Pharmaceuticals, Inc. composição, usos e método para reduzir neutropenia
US11633393B2 (en) 2017-01-06 2023-04-25 Beyondspring Pharmaceuticals, Inc. Tubulin binding compounds and therapeutic use thereof
EP3576733A4 (en) 2017-02-01 2020-11-25 Beyondspring Pharmaceuticals, Inc. NEUTROPENIA REDUCTION METHOD
AU2018221379B2 (en) 2017-02-16 2021-11-04 ViiV Healthcare UK (No.3) Limited Crystalline forms of cabotegravir sodium
KR20200112881A (ko) 2018-01-24 2020-10-05 비욘드스프링 파마수티컬스, 인코포레이티드. 플리나불린의 투여를 통해 혈소판감소증을 감소시키는 조성물 및 방법
TW202028208A (zh) 2018-10-09 2020-08-01 瑞士商諾華公司 N-(4-氟-3-(6-(3-甲基吡啶-2-基)-[1,2,4]三唑并[1,5-a]嘧啶-2-基)苯基)-2,4-二甲基㗁唑-5-甲醯胺固體形式
EP4319751A4 (en) 2021-04-09 2025-02-26 Beyondspring Pharmaceuticals, Inc. THERAPEUTIC COMPOSITIONS AND METHODS FOR THE TREATING OF TUMORS

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623810B2 (fr) 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
FR2779726B1 (fr) 1998-06-15 2001-05-18 Sanofi Sa Forme polymorphe de l'hydrogenosulfate de clopidogrel
WO2002018357A1 (en) 2000-08-29 2002-03-07 Rpg Life Sciences Limited A ONE-POT PROCESS FOR THE PREPARATION OF PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS OF 4, 5, 6, 7 - TETRAHYDROTHIENO (3,2-c) PYRIDINE DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY
GB0125708D0 (en) 2001-10-26 2001-12-19 Generics Uk Ltd Novel compounds and processes
CA2470479A1 (en) * 2001-12-18 2003-06-26 Teva Pharmaceutical Industries Ltd. Polymorphs of clopidogrel hydrogensulfate
AU2003257541A1 (en) * 2002-08-27 2004-03-19 Yamanouchi Pharmaceutical Co., Ltd. Novel crystals
CZ297472B6 (cs) * 2002-08-27 2006-12-13 Zentiva, A.S. Zpusob výroby clopidogrelu hydrogensulfátu krystalické formy I
WO2004048385A2 (en) * 2002-11-28 2004-06-10 Instytut Farmaceutyczny A process for the preparation of crystalline form 1 or clopidogrel hydrogen sulfate
WO2004081016A1 (en) * 2003-03-12 2004-09-23 Cadila Healthcare Limited Polymorphs and amorphous form of (s) - (+) -clopidogrel bisulfate
CN1812993B (zh) * 2003-07-02 2011-06-29 埃吉斯药物工厂 制备抑制血小板聚集药物的结晶性多晶型物的方法
BR0318449A (pt) 2003-08-04 2006-08-01 Wockhardt Ltd processo para fabricação de (+)-(s)-clopidogrel bissulfato forma-i
DE10337773A1 (de) * 2003-08-13 2005-03-24 Krka Tovarna Zdravil, D.D. Kristallisation von festen Formen von Clopidogrel-Additionssalzen
EP1723141A4 (en) * 2004-03-05 2007-10-10 Ipca Lab Ltd MOST TECHNICAL PROCESS FOR THE PREPARATION OF CLOPIDOGRAPHYDROGENSULFATE

Also Published As

Publication number Publication date
EA010198B1 (ru) 2008-06-30
US20090234123A1 (en) 2009-09-17
NO339878B1 (no) 2017-02-13
HRP20160757T1 (hr) 2016-08-12
SI1740593T1 (sl) 2016-08-31
HUE029459T2 (en) 2017-02-28
NO20065321L (no) 2007-01-09
EP1740593A1 (en) 2007-01-10
EP1740593B1 (en) 2016-04-06
WO2005100364A1 (en) 2005-10-27
US7999106B2 (en) 2011-08-16
ES2577303T3 (es) 2016-07-14
EA200601822A1 (ru) 2007-02-27

Similar Documents

Publication Publication Date Title
PL1740593T3 (pl) Sposoby wytwarzania wodorosiarczanu klopidogrelu w formie polimorficznej I
IL194522A0 (en) Process for the preparation of prasugrel
IL181303A0 (en) Method for the production of dihydropteridinones
IL188330A0 (en) Processes for the preparation of
IL194718A0 (en) Process for the preparation of cinacalcet base
ZA200804264B (en) Process for the preparation of ferri-succinylcasein
IL176633A0 (en) Process for the manufacture of curved objects
PL1807395T3 (pl) Sposób syntezy n-alkoksyamin
IL182421A0 (en) Process for the preparation of pyrazoles
ZA200601910B (en) Process for the preparation of organosilances
ZA200703495B (en) Process for the preparation of irbesartan hydrochloride
SG135196A1 (en) Process for the preparation of enantiomerically pure 1-substituted-3- aminoalcohols
ZA200704972B (en) Processes for producing 4-aminoquinazolines
HU0402017D0 (en) Environment-friend process for the synthesis of quaternary ammonio-steroids
HU0401379D0 (en) Process for the preparation of risperidon
IL180345A0 (en) Improved process for the manufacture of mirtazapine
EP2170902A4 (en) IMPROVED METHOD FOR SYNTHESIS OF OLANZAPINE
ZA200809735B (en) Process for the preparation of polymorphic forms of clopidogrel hydrogen sulfate
EP1863775A4 (en) PROCESS FOR THE PREPARATION OF A CRYSTALLINE FORM I OF OLANZAPINE
IL178960A0 (en) Process for the preparation of pyridin-2-ylmethylsulphinyl-1h-benzimidazol compounds
IL177353A0 (en) Process for the preparation of aq4n
HUP0401272A3 (en) Process for the production of crystalline polymorphous form of clopidogrel hydrogen sulfate
HUP0401269A3 (en) Process for the production of amorphous form of clopidogrel hydrogen sulfate
SI1732916T1 (sl) Postopek za pripravo alkoksikarbonilmetoksi-ciklopentanov
IL178237A0 (en) Process for the preparation of rosiglitazone