PL1735274T3 - Niepeptydowe inhibitory metaloproteinaz macierzy zewnątrzkomórkowej - Google Patents
Niepeptydowe inhibitory metaloproteinaz macierzy zewnątrzkomórkowejInfo
- Publication number
- PL1735274T3 PL1735274T3 PL05729212T PL05729212T PL1735274T3 PL 1735274 T3 PL1735274 T3 PL 1735274T3 PL 05729212 T PL05729212 T PL 05729212T PL 05729212 T PL05729212 T PL 05729212T PL 1735274 T3 PL1735274 T3 PL 1735274T3
- Authority
- PL
- Poland
- Prior art keywords
- matrix metalloproteinases
- compounds
- disclosed
- methods
- nonpeptide inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/20—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
- C07C311/43—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55538004P | 2004-03-22 | 2004-03-22 | |
| EP05729212A EP1735274B1 (en) | 2004-03-22 | 2005-03-21 | Nonpeptide inhibitors of matrix metalloproteinases |
| PCT/US2005/009263 WO2005092844A1 (en) | 2004-03-22 | 2005-03-21 | Nonpeptide inhibitors of matrix metalloproteinases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1735274T3 true PL1735274T3 (pl) | 2010-05-31 |
Family
ID=34963517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05729212T PL1735274T3 (pl) | 2004-03-22 | 2005-03-21 | Niepeptydowe inhibitory metaloproteinaz macierzy zewnątrzkomórkowej |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8129406B2 (pl) |
| EP (1) | EP1735274B1 (pl) |
| JP (2) | JP2007530546A (pl) |
| KR (1) | KR20070046025A (pl) |
| CN (1) | CN101001834B (pl) |
| AT (1) | ATE449760T1 (pl) |
| AU (1) | AU2005227311B2 (pl) |
| CA (1) | CA2560739A1 (pl) |
| DE (1) | DE602005017879D1 (pl) |
| DK (1) | DK1735274T3 (pl) |
| ES (1) | ES2338243T3 (pl) |
| MX (1) | MXPA06010974A (pl) |
| NZ (1) | NZ550621A (pl) |
| PL (1) | PL1735274T3 (pl) |
| PT (1) | PT1735274E (pl) |
| SI (1) | SI1735274T1 (pl) |
| WO (1) | WO2005092844A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009079375A1 (en) * | 2007-12-14 | 2009-06-25 | Georgetown University | Histone deacetylase inhibitors |
| GB0817207D0 (en) * | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | therapeutic apsac compounds and their use |
| US20110200662A1 (en) * | 2008-10-22 | 2011-08-18 | Arnold Glazier | Method For The Treatment Of Proliferative Disorders Of The Eye |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5753653A (en) * | 1995-12-08 | 1998-05-19 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
| ATE225343T1 (de) | 1995-12-20 | 2002-10-15 | Hoffmann La Roche | Matrix-metalloprotease inhibitoren |
| KR20000011095A (ko) * | 1996-05-17 | 2000-02-25 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | 비페닐술폰아미드 매트릭스 메탈로프로테이나아제 억제제 |
| EP0818442A3 (en) | 1996-07-12 | 1998-12-30 | Pfizer Inc. | Cyclic sulphone derivatives as inhibitors of metalloproteinases and of the production of tumour necrosis factor |
| US5977408A (en) * | 1996-10-16 | 1999-11-02 | American Cyanamid Company | Preparation and use of β-sulfonamido hydroxamic acids as matrix metalloproteinase and TACE inhibitors |
| JP2001502326A (ja) * | 1996-10-16 | 2001-02-20 | アメリカン・サイアナミド・カンパニー | マトリクス金属プロテナイーゼおよびＴＡＣＥに対する阻害薬としてのβ―スルホンアミドヒドロキサム酸 |
| CN1253474A (zh) * | 1997-03-04 | 2000-05-17 | 孟山都公司 | 磺酰基二价芳基或杂芳基异羟肟酸化合物 |
| GB9708133D0 (en) | 1997-04-22 | 1997-06-11 | British Biotech Pharm | Novel use of matrix metalloproteinase inhibitors |
| AR035478A1 (es) * | 1999-01-27 | 2004-06-02 | Wyeth Corp | Acido amida-hidroxamico, acido acetilenico, beta-sulfonamido y fosfinico como inhibidores de la tace, uso de los mismos para la manufactura de un medicamento y composicion farmaceutica que los contiene |
| US6326516B1 (en) * | 1999-01-27 | 2001-12-04 | American Cyanamid Company | Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors |
| AUPP982399A0 (en) | 1999-04-19 | 1999-05-13 | Fujisawa Pharmaceutical Co., Ltd. | Mmp inhibitor |
| CA2434044A1 (en) * | 2001-01-11 | 2002-07-18 | Bristol-Myers Squibb Pharma Company | 1,2-disubstituted cyclic inhibitors of matrix metallorproteases and tnf-alpha |
-
2005
- 2005-03-21 AT AT05729212T patent/ATE449760T1/de active
- 2005-03-21 WO PCT/US2005/009263 patent/WO2005092844A1/en active Application Filing
- 2005-03-21 SI SI200530912T patent/SI1735274T1/sl unknown
- 2005-03-21 PT PT05729212T patent/PT1735274E/pt unknown
- 2005-03-21 NZ NZ550621A patent/NZ550621A/en unknown
- 2005-03-21 KR KR1020067021920A patent/KR20070046025A/ko not_active Application Discontinuation
- 2005-03-21 DK DK05729212.0T patent/DK1735274T3/da active
- 2005-03-21 MX MXPA06010974A patent/MXPA06010974A/es active IP Right Grant
- 2005-03-21 CN CN200580016346XA patent/CN101001834B/zh not_active Expired - Fee Related
- 2005-03-21 EP EP05729212A patent/EP1735274B1/en not_active Not-in-force
- 2005-03-21 CA CA002560739A patent/CA2560739A1/en not_active Abandoned
- 2005-03-21 ES ES05729212T patent/ES2338243T3/es active Active
- 2005-03-21 US US10/593,748 patent/US8129406B2/en not_active Expired - Fee Related
- 2005-03-21 PL PL05729212T patent/PL1735274T3/pl unknown
- 2005-03-21 DE DE602005017879T patent/DE602005017879D1/de active Active
- 2005-03-21 AU AU2005227311A patent/AU2005227311B2/en not_active Expired - Fee Related
- 2005-03-21 JP JP2007505043A patent/JP2007530546A/ja active Pending
-
2011
- 2011-01-21 JP JP2011011407A patent/JP2011079866A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005092844A1 (en) | 2005-10-06 |
| DK1735274T3 (da) | 2010-03-29 |
| KR20070046025A (ko) | 2007-05-02 |
| CN101001834B (zh) | 2011-06-29 |
| EP1735274B1 (en) | 2009-11-25 |
| US8129406B2 (en) | 2012-03-06 |
| MXPA06010974A (es) | 2007-04-23 |
| NZ550621A (en) | 2009-11-27 |
| CA2560739A1 (en) | 2005-10-06 |
| JP2011079866A (ja) | 2011-04-21 |
| CN101001834A (zh) | 2007-07-18 |
| ATE449760T1 (de) | 2009-12-15 |
| ES2338243T3 (es) | 2010-05-05 |
| DE602005017879D1 (de) | 2010-01-07 |
| SI1735274T1 (sl) | 2010-03-31 |
| JP2007530546A (ja) | 2007-11-01 |
| US20080312329A1 (en) | 2008-12-18 |
| EP1735274A1 (en) | 2006-12-27 |
| PT1735274E (pt) | 2009-12-11 |
| AU2005227311B2 (en) | 2012-03-15 |
| AU2005227311A1 (en) | 2005-10-06 |
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