PL1680426T3 - Pochodne 1,3,4-triazafenalenu i 1,3,4,6-tetraazafenalenu - Google Patents

Pochodne 1,3,4-triazafenalenu i 1,3,4,6-tetraazafenalenu

Info

Publication number
PL1680426T3
PL1680426T3 PL04729442T PL04729442T PL1680426T3 PL 1680426 T3 PL1680426 T3 PL 1680426T3 PL 04729442 T PL04729442 T PL 04729442T PL 04729442 T PL04729442 T PL 04729442T PL 1680426 T3 PL1680426 T3 PL 1680426T3
Authority
PL
Poland
Prior art keywords
compounds
phenalene
triaza
treatment
control
Prior art date
Application number
PL04729442T
Other languages
English (en)
Inventor
Kin-Chun Luk
Zhuming Zhang
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PL1680426T3 publication Critical patent/PL1680426T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
PL04729442T 2003-06-10 2004-04-26 Pochodne 1,3,4-triazafenalenu i 1,3,4,6-tetraazafenalenu PL1680426T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47731803P 2003-06-10 2003-06-10
EP04729442A EP1680426B1 (en) 2003-06-10 2004-04-26 1.3.4-triaza-phenalene and 1,3,4,6-tetraazaphenalene derivatives
PCT/EP2004/050608 WO2004111055A1 (en) 2003-06-10 2004-04-26 1.3.4-triaza-phenalene and 1,3,4,6-tetraazaphenalene derivatives

Publications (1)

Publication Number Publication Date
PL1680426T3 true PL1680426T3 (pl) 2008-02-29

Family

ID=33551702

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04729442T PL1680426T3 (pl) 2003-06-10 2004-04-26 Pochodne 1,3,4-triazafenalenu i 1,3,4,6-tetraazafenalenu

Country Status (15)

Country Link
US (1) US7217717B2 (pl)
EP (1) EP1680426B1 (pl)
JP (1) JP2006527235A (pl)
KR (1) KR100753385B1 (pl)
CN (1) CN100378101C (pl)
AT (1) ATE373661T1 (pl)
AU (1) AU2004247418B2 (pl)
BR (1) BRPI0411126A (pl)
CA (1) CA2527832A1 (pl)
DE (1) DE602004009097T2 (pl)
ES (1) ES2293251T3 (pl)
MX (1) MXPA05013145A (pl)
PL (1) PL1680426T3 (pl)
RU (1) RU2346946C2 (pl)
WO (1) WO2004111055A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5439380B2 (ja) * 2007-10-03 2014-03-12 エーザイ インク． Ｐａｒｐ阻害化合物、組成物及び使用方法
RU2498986C2 (ru) * 2011-07-20 2013-11-20 Учреждение Российской Академии Наук Институт Проблем Химической Физики Ран (Ипхф Ран) ТЕТРАЦИАНОЗАМЕЩЕННЫЕ 1,4,9b-ТРИАЗАФЕНАЛЕНЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ
CN104945406B (zh) * 2015-05-25 2017-10-10 苏州康润医药有限公司 氮杂非那烯‑3‑酮的衍生物、其制备方法及其作为parp抑制剂的应用
CN115894486B (zh) * 2021-09-30 2024-02-09 北京赛特明强医药科技有限公司 一种氢化吡啶并喹唑啉类化合物、组合物及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9300059D0 (en) 1992-01-20 1993-03-03 Zeneca Ltd Quinazoline derivatives
US5739170A (en) * 1992-09-11 1998-04-14 The Regents Of The University Of California Inhibitors of metazoan parasite proteases
PT752813E (pt) * 1992-09-11 2003-04-30 Univ California Inibidores de proteases de parasitas metazoarios
EP0817775B1 (en) 1995-03-30 2001-09-12 Pfizer Inc. Quinazoline derivatives
US5747498A (en) * 1996-05-28 1998-05-05 Pfizer Inc. Alkynyl and azido-substituted 4-anilinoquinazolines
TW436485B (en) * 1997-08-01 2001-05-28 American Cyanamid Co Substituted quinazoline derivatives
TR200003166T2 (tr) 1998-04-29 2001-02-21 Osi Pharmaceuticals, Inc. N-(3-etinilfenilamino)-6, 7-bis(2-metoksietoksi)-4-kuinozolamin mesilat anhidrat ve monohidrat.
UA74803C2 (uk) 1999-11-11 2006-02-15 Осі Фармасьютікалз, Інк. Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
JP2004529075A (ja) * 2000-11-03 2004-09-24 ニューロクライン バイオサイエンシーズ， インコーポレイテッド Ｃｒｆレセプターアンタゴニストおよびそれに関する方法
EP2173338A1 (en) * 2007-07-06 2010-04-14 OSI Pharmaceuticals, Inc. Combination anti-cancer therapy

Also Published As

Publication number Publication date
RU2346946C2 (ru) 2009-02-20
US20040254205A1 (en) 2004-12-16
JP2006527235A (ja) 2006-11-30
MXPA05013145A (es) 2006-03-17
US7217717B2 (en) 2007-05-15
ES2293251T3 (es) 2008-03-16
EP1680426B1 (en) 2007-09-19
CA2527832A1 (en) 2004-12-23
CN1805964A (zh) 2006-07-19
KR20060017854A (ko) 2006-02-27
EP1680426A1 (en) 2006-07-19
AU2004247418A1 (en) 2004-12-23
DE602004009097D1 (de) 2007-10-31
ATE373661T1 (de) 2007-10-15
WO2004111055A1 (en) 2004-12-23
AU2004247418B2 (en) 2009-11-05
KR100753385B1 (ko) 2007-08-30
CN100378101C (zh) 2008-04-02
DE602004009097T2 (de) 2008-06-19
BRPI0411126A (pt) 2006-07-18
RU2006100034A (ru) 2006-08-27

Similar Documents

Publication Publication Date Title
WO2002057261A3 (en) Diaminothiazoles and their use as inhibitors of cyclin-dependent kinase
TW200407326A (en) Pyrimido compounds having antiproliferative activity
GEP20074213B (en) Novel inhibitors of kinases
IL147271A0 (en) Compounds that bind her2
CA2223016A1 (en) Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of her-2 autophosphorylation properties
BG106465A (en) Tyrosine kinase inhibitors
HK1087613A1 (en) Quinazoline derivatives and their use in the treatment of cancer
MXPA04004492A (es) Indazolilpirrolotriazinas c-5 modificadas.
TR200200717T2 (tr) Terapötik kinazolin türevleri.
TW200420565A (en) C-6 modified indazolylpyrrolotriazines
JO2248B1 (en) Pirazolobenzodiazepines
TNSN05188A1 (en) 4-aminopyrimidine-5-one
DE60215682D1 (de) AZAOXOINDOL DERIVATE ALS Trk PROTEIN KINASE HEMMSTOFFE ZUR BEHANDLUNG VON KREBS UND CHRONISCHEM SCHMERZ
PL342614A1 (en) Anticarcinogenic drugs
EP1427418A4 (en) PIPERAZINONE COMPOUNDS AS ANTITUMOR AND ANTICANCER AGENTS AND METHODS OF TREATMENT
TW200612929A (en) Novel 2,6-diaminopyridine-3-one derivatives
WO2005103034A8 (en) Novel piperidine substituted diaminothiazoles
PL1680426T3 (pl) Pochodne 1,3,4-triazafenalenu i 1,3,4,6-tetraazafenalenu
IL161462A0 (en) Combinations comprising a selective cyclooxygenase-2 inhibitor
BRPI0511826A (pt) derivados de 2,4-diaminotiazol-5-ona
WO2003037257A3 (en) Methods and compositions for the diagnosis and treatment of cellular proliferation disorders using 20750
WO2003080624A3 (en) Dithiolopyrrolone derivatives useful in the treatment of proliferative diseases
HK1082727A1 (en) 2" oxo-voruscharin and derivatives thereof
WO2001079505A3 (en) INHIBITION OF BONE TUMOR FORMATION USING ANTISENSE cDNA THERAPY
WO2003038400A3 (en) Methods and compositions for the treatment and diagnosis of cellular proliferation disorders using 54394