PL1643977T3 - Wielocząstkowa postać leku, zawierającego mukoadhezyjnie sformułowane peptydowe lub proteinowe substancje czynne oraz sposób wytwarzania tej postaci leku - Google Patents
Wielocząstkowa postać leku, zawierającego mukoadhezyjnie sformułowane peptydowe lub proteinowe substancje czynne oraz sposób wytwarzania tej postaci lekuInfo
- Publication number
- PL1643977T3 PL1643977T3 PL04741056T PL04741056T PL1643977T3 PL 1643977 T3 PL1643977 T3 PL 1643977T3 PL 04741056 T PL04741056 T PL 04741056T PL 04741056 T PL04741056 T PL 04741056T PL 1643977 T3 PL1643977 T3 PL 1643977T3
- Authority
- PL
- Poland
- Prior art keywords
- dosage form
- pharmaceutical dosage
- producing
- multiparticle
- active substances
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10332160A DE10332160A1 (de) | 2003-07-15 | 2003-07-15 | Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Peptid- oder Protein-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
PCT/EP2004/007882 WO2005007139A2 (de) | 2003-07-15 | 2004-07-15 | Multipartikuläre arzneiform, enthaltend mucoadhaesiv formulierte peptid- oder protein-wirkstoffe, sowie ein verfahren zur herstellung der arzneiform |
EP04741056A EP1643977B1 (de) | 2003-07-15 | 2004-07-15 | Multipartikuläre arzneiform, enthaltend mucoadhaesiv formulierte peptid- oder protein-wirkstoffe, sowie ein verfahren zur herstellung der arzneiform |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1643977T3 true PL1643977T3 (pl) | 2008-04-30 |
Family
ID=33560136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL04741056T PL1643977T3 (pl) | 2003-07-15 | 2004-07-15 | Wielocząstkowa postać leku, zawierającego mukoadhezyjnie sformułowane peptydowe lub proteinowe substancje czynne oraz sposób wytwarzania tej postaci leku |
Country Status (13)
Country | Link |
---|---|
US (1) | US8734849B2 (pl) |
EP (1) | EP1643977B1 (pl) |
JP (1) | JP5026787B2 (pl) |
KR (1) | KR100882155B1 (pl) |
CN (1) | CN100528145C (pl) |
AT (1) | ATE374601T1 (pl) |
BR (1) | BRPI0411986A (pl) |
CA (1) | CA2532487C (pl) |
DE (2) | DE10332160A1 (pl) |
ES (1) | ES2293286T3 (pl) |
IL (1) | IL173078A (pl) |
PL (1) | PL1643977T3 (pl) |
WO (1) | WO2005007139A2 (pl) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001034119A2 (en) | 1999-11-12 | 2001-05-17 | Abbott Laboratories | Inhibitors of crystallization in a solid dispersion |
US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
DE102004036437A1 (de) * | 2004-07-27 | 2006-03-23 | Röhm GmbH & Co. KG | Multipartikuläre Arzneiform für wenig lösliche Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
EP1781257B1 (en) * | 2004-08-13 | 2018-12-19 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
DE102004059792A1 (de) * | 2004-12-10 | 2006-06-14 | Röhm GmbH & Co. KG | Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Nukleinsäure-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
DE102005007059A1 (de) | 2005-02-15 | 2006-08-24 | Röhm GmbH & Co. KG | Teilneutralisiertes anionisches (Meth)acrylat-Copolymer |
WO2006122835A1 (en) | 2005-05-18 | 2006-11-23 | Da Volterra | Colonic delivery of adsorbents |
DE102005032806A1 (de) * | 2005-07-12 | 2007-01-18 | Röhm Gmbh | Verwendung eines teilneutralisierten, anionischen (Meth)acrylat-Copolymers als Überzug für die Herstellung einer Arzneiform mit einer Wirkstofffreisetzung bei erniedrigten pH-Werten |
AU2007215304B2 (en) * | 2006-02-09 | 2012-06-14 | Alba Therapeutics Corporation | Formulations for a tight junction effector |
US8048413B2 (en) | 2006-05-17 | 2011-11-01 | Helene Huguet | Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules |
DE102006035549A1 (de) * | 2006-07-27 | 2008-01-31 | Evonik Röhm Gmbh | Arzneiform mit mindestens zweischichtiger Trennschicht |
EP2167044A1 (en) * | 2007-06-11 | 2010-03-31 | BioCure, Inc. | Mucoadhesive vesicles for drug delivery |
ITMI20080807A1 (it) | 2008-05-05 | 2009-11-06 | Antibioticos Spa | Procedimento per la preparazione di tigeciclina in forma amorfa |
US8632805B2 (en) * | 2008-06-20 | 2014-01-21 | Mutual Pharmaceutical Company, Inc. | Controlled-release formulations, method of manufacture, and use thereof |
US7794750B2 (en) * | 2008-06-20 | 2010-09-14 | Mutual Pharmaceutical Company, Inc. | Controlled-release formulations, method of manufacture, and use thereof |
CN101744725B (zh) * | 2008-12-09 | 2013-04-17 | 北京华素制药股份有限公司 | 缓释微丸包衣生产工艺参数的优化方法 |
CN102335431B (zh) * | 2010-07-14 | 2015-08-26 | 上海蓝心医药科技有限公司 | 一种给药组合物及其制备和使用方法 |
EP2364690A1 (en) * | 2010-02-12 | 2011-09-14 | Centro De Ingenieria Genetica Y Biotecnologia | Orally administrable pharmaceutical pellet of epidermal growth factor |
AU2010346995B2 (en) * | 2010-02-25 | 2014-12-04 | Evonik Operations Gmbh | Pharmaceutical or neutraceutical formulation |
WO2013093823A2 (en) | 2011-12-20 | 2013-06-27 | Vyome Biosciences Pvt Ltd | Topical oil composition for the treatment of fungal infections |
US20150250888A1 (en) * | 2012-09-28 | 2015-09-10 | Evonik Industries Ag | Process for preparing aqueous dispersions |
JP5946743B2 (ja) * | 2012-10-19 | 2016-07-06 | フロイント産業株式会社 | キトサンコーティング溶液及びその製造方法、並びに大腸ドラッグデリバリーシステム製剤及びその製造方法 |
DE102013207083A1 (de) | 2013-04-19 | 2014-10-23 | Leibniz-Institut Für Polymerforschung Dresden E.V. | Verwendung von Chitosan und/oder dessen Derivaten in Baumaterialien |
KR101814895B1 (ko) * | 2013-06-04 | 2018-01-04 | 바이옴 바이오사이언스 피브이티. 엘티디. | 코팅된 입자 및 이를 포함하는 조성물 |
AU2015212312A1 (en) | 2014-01-29 | 2016-08-18 | Vyome Therapeutics Limited | Treatments for resistant acne |
US10588864B2 (en) | 2016-03-11 | 2020-03-17 | Gateway Pharmaceuticals LLC | Pharmaceutical compositions for colon-specific delivery |
EP3243505A1 (en) | 2016-05-13 | 2017-11-15 | Zaklady Farmaceutyczne Polpharma SA | A pharmaceutical composition comprising amorphous apixaban |
US20190030003A1 (en) * | 2017-03-21 | 2019-01-31 | Bioduro, Llc | Gastrointestinal-protective formulations for oral delivery of proteins and peptides |
EP3459528B1 (en) | 2017-09-20 | 2022-11-23 | Tillotts Pharma Ag | Preparation of solid dosage forms comprising antibodies by solution/suspension layering |
JP7244536B2 (ja) | 2018-04-06 | 2023-03-22 | キャプシュゲル・ベルジウム・エヌ・ヴィ | メタクリル酸メチル-メタクリル酸コポリマーからなる低アスペクト比の粒子のための噴霧乾燥方法 |
AU2019275406A1 (en) | 2018-05-24 | 2020-07-16 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
MX2020012459A (es) | 2018-05-24 | 2021-04-28 | Celanese Eva Performance Polymers Llc | Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular. |
US11918011B2 (en) * | 2018-06-01 | 2024-03-05 | Danisco Us Inc. | High-payload, non-porous, enzyme-containing coated granules and use of same |
CN109620832B (zh) * | 2019-01-14 | 2021-01-01 | 大连大学 | 甘氨胆酸在制备抗乳腺增生药物中的应用 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW209174B (pl) | 1991-04-19 | 1993-07-11 | Takeda Pharm Industry Co Ltd | |
US6468959B1 (en) * | 1991-12-05 | 2002-10-22 | Alfatec-Pharm Gmbh | Peroral dosage form for peptide containing medicaments, in particular insulin |
US5240269A (en) * | 1992-01-16 | 1993-08-31 | Miner Enterprises, Inc. | Bike suspension |
ES2108258T3 (es) | 1992-01-17 | 1997-12-16 | Alfatec Pharma Gmbh | Granulos que contienen sustancias medicamentosas peptidicas y su preparacion asi como su empleo. |
AU1677095A (en) * | 1994-01-11 | 1995-08-01 | Alkermes Controlled Therapeutics, Inc. | Oral dosage form of desmopressin (ddavp) |
US5849327A (en) * | 1994-07-29 | 1998-12-15 | Advanced Polymer Systems, Inc. | Delivery of drugs to the lower gastrointestinal tract |
GB9700624D0 (en) * | 1997-01-14 | 1997-03-05 | Danbiosyst Uk | Drug delivery composition |
JPH11116499A (ja) * | 1997-10-16 | 1999-04-27 | Asahi Chem Ind Co Ltd | 生理活性ペプチドを含有した経口投与用ナノスフェア |
DE19845358A1 (de) * | 1998-10-02 | 2000-04-06 | Roehm Gmbh | Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe |
ATE366119T1 (de) * | 1999-08-09 | 2007-07-15 | Dainippon Sumitomo Pharma Co | Chitosanpulver enthaltende feste zubereitungen und verfahren zu deren herstellung |
DE19960154A1 (de) | 1999-12-14 | 2001-07-12 | Lohmann Therapie Syst Lts | Flache Arzneizubereitung zur transmucosalen Verabreichung von Oxycodon oder einem vergleichbaren Wirkstoff in der Mundhöhle, für die Anwendung in der Schmerztherapie und Suchttherapie |
DE10024451A1 (de) | 2000-05-18 | 2001-11-29 | Asta Medica Ag | Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung |
IT1318618B1 (it) | 2000-07-10 | 2003-08-27 | A C R Applied Coating Res S A | Microsfere bioadesive a rilascio rapido per la somministrazionesublinguale di principi attivi. |
DE10038571A1 (de) | 2000-08-03 | 2002-02-14 | Knoll Ag | Zusammensetzungen und Dosierungsformen zur Anwendung in der Mundhöhle bei der Bhandlung von Mykosen |
US6673574B2 (en) | 2000-11-30 | 2004-01-06 | Unigene Laboratories Inc. | Oral delivery of peptides using enzyme-cleavable membrane translocators |
WO2002064148A2 (en) | 2001-02-16 | 2002-08-22 | Shimizu Pharmaceutical Co., Ltd. | Oral formulations containing mucopolysaccharide for small intestine delivery and their use in the treatment circulatory disorders |
US20030017195A1 (en) | 2001-07-20 | 2003-01-23 | Samir Mitragotri | Method for oral drug delivery |
SK1732004A3 (sk) * | 2001-10-15 | 2005-06-02 | R�Hm Gmbh & Co. Kg | Použitie kopolyméru na prípravu liekovej formy, ktorá ako účinnú látku obsahuje peptid alebo proteín |
DE102004036437A1 (de) * | 2004-07-27 | 2006-03-23 | Röhm GmbH & Co. KG | Multipartikuläre Arzneiform für wenig lösliche Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
DE102006035549A1 (de) * | 2006-07-27 | 2008-01-31 | Evonik Röhm Gmbh | Arzneiform mit mindestens zweischichtiger Trennschicht |
-
2003
- 2003-07-15 DE DE10332160A patent/DE10332160A1/de not_active Withdrawn
-
2004
- 2004-07-15 US US10/564,096 patent/US8734849B2/en active Active
- 2004-07-15 CA CA2532487A patent/CA2532487C/en active Active
- 2004-07-15 CN CNB2004800202169A patent/CN100528145C/zh active Active
- 2004-07-15 BR BRPI0411986-0A patent/BRPI0411986A/pt not_active Application Discontinuation
- 2004-07-15 ES ES04741056T patent/ES2293286T3/es active Active
- 2004-07-15 EP EP04741056A patent/EP1643977B1/de active Active
- 2004-07-15 DE DE502004005154T patent/DE502004005154D1/de active Active
- 2004-07-15 KR KR1020067000823A patent/KR100882155B1/ko active IP Right Grant
- 2004-07-15 PL PL04741056T patent/PL1643977T3/pl unknown
- 2004-07-15 AT AT04741056T patent/ATE374601T1/de active
- 2004-07-15 JP JP2006519883A patent/JP5026787B2/ja active Active
- 2004-07-15 WO PCT/EP2004/007882 patent/WO2005007139A2/de active IP Right Grant
-
2006
- 2006-01-11 IL IL173078A patent/IL173078A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ATE374601T1 (de) | 2007-10-15 |
WO2005007139A3 (de) | 2005-05-12 |
CN1822821A (zh) | 2006-08-23 |
US20070026082A1 (en) | 2007-02-01 |
BRPI0411986A (pt) | 2006-08-29 |
US8734849B2 (en) | 2014-05-27 |
KR20060041227A (ko) | 2006-05-11 |
DE502004005154D1 (de) | 2007-11-15 |
CA2532487C (en) | 2012-09-18 |
WO2005007139A2 (de) | 2005-01-27 |
EP1643977B1 (de) | 2007-10-03 |
KR100882155B1 (ko) | 2009-02-06 |
EP1643977A2 (de) | 2006-04-12 |
CA2532487A1 (en) | 2005-01-27 |
CN100528145C (zh) | 2009-08-19 |
ES2293286T3 (es) | 2008-03-16 |
IL173078A0 (en) | 2006-06-11 |
IL173078A (en) | 2010-05-31 |
DE10332160A1 (de) | 2005-02-03 |
JP5026787B2 (ja) | 2012-09-19 |
JP2009513553A (ja) | 2009-04-02 |
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