PL131389B1 - Method of obtaining n-acyl derivatives of triptamines - Google Patents

Method of obtaining n-acyl derivatives of triptamines Download PDF

Info

Publication number
PL131389B1
PL131389B1 PL22786080A PL22786080A PL131389B1 PL 131389 B1 PL131389 B1 PL 131389B1 PL 22786080 A PL22786080 A PL 22786080A PL 22786080 A PL22786080 A PL 22786080A PL 131389 B1 PL131389 B1 PL 131389B1
Authority
PL
Poland
Prior art keywords
formula
methyl
chloride
hydrogen
methoxy
Prior art date
Application number
PL22786080A
Other languages
English (en)
Polish (pl)
Other versions
PL227860A1 (nl
Inventor
Marian Eckstein
Stanislaw Misztal
Barbara Sienkiewicz
Andrzej Roszkowski
Original Assignee
Krakowskie Zaklady Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krakowskie Zaklady Pharma filed Critical Krakowskie Zaklady Pharma
Priority to PL22786080A priority Critical patent/PL131389B1/pl
Priority to HU339881A priority patent/HU187471B/hu
Priority to NL8105139A priority patent/NL189964C/nl
Publication of PL227860A1 publication Critical patent/PL227860A1/xx
Publication of PL131389B1 publication Critical patent/PL131389B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
PL22786080A 1980-11-13 1980-11-13 Method of obtaining n-acyl derivatives of triptamines PL131389B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PL22786080A PL131389B1 (en) 1980-11-13 1980-11-13 Method of obtaining n-acyl derivatives of triptamines
HU339881A HU187471B (en) 1980-11-13 1981-11-13 Process for preparing n-acyl-triptamine derivatives and pharmaceutical compositions containing them as active agents
NL8105139A NL189964C (nl) 1980-11-13 1981-11-13 Werkwijze voor het bereiden van n-acylderivaten van tryptamine.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL22786080A PL131389B1 (en) 1980-11-13 1980-11-13 Method of obtaining n-acyl derivatives of triptamines

Publications (2)

Publication Number Publication Date
PL227860A1 PL227860A1 (nl) 1982-06-21
PL131389B1 true PL131389B1 (en) 1984-11-30

Family

ID=20005887

Family Applications (1)

Application Number Title Priority Date Filing Date
PL22786080A PL131389B1 (en) 1980-11-13 1980-11-13 Method of obtaining n-acyl derivatives of triptamines

Country Status (3)

Country Link
HU (1) HU187471B (nl)
NL (1) NL189964C (nl)
PL (1) PL131389B1 (nl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6762182B1 (en) 1999-01-07 2004-07-13 Vanderbilt University Converting cox inhibition compounds that are not COX-2 selective inhibitors to derivatives that are COX-2 selective inhibitors
US6207700B1 (en) 1999-01-07 2001-03-27 Vanderbilt University Amide derivatives for antiangiogenic and/or antitumorigenic use
US6306890B1 (en) 1999-08-30 2001-10-23 Vanderbilt University Esters derived from indolealkanols and novel amides derived from indolealkylamides that are selective COX-2 inhibitors
JP2007534702A (ja) 2004-04-26 2007-11-29 バンダービルト・ユニバーシティ 胃腸毒性の低い治療薬としてのインドール酢酸、及びインデン酢酸誘導体
CN101528222A (zh) 2006-06-19 2009-09-09 范德比尔特大学 用于诊断性和治疗性靶向cox-2的方法和组合物
US9346803B2 (en) 2011-10-17 2016-05-24 Vanderbilt University Indomethacin analogs for the treatment of castrate-resistant prostate cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1453808A (fr) * 1964-04-20 1966-07-22 Nouveaux aminoacétyl-3-indoles n'-monosubstitués et leur procédé de préparation
CH444160A (de) * 1964-07-02 1967-09-30 Sandoz Ag Verfahren zur Herstellung von neuen Indolderivaten

Also Published As

Publication number Publication date
NL189964C (nl) 1993-09-16
PL227860A1 (nl) 1982-06-21
HU187471B (en) 1986-01-28
NL189964B (nl) 1993-04-16
NL8105139A (nl) 1982-06-01

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