PL124284B1 - Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group - Google Patents

Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group Download PDF

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Publication number
PL124284B1
PL124284B1 PL1979219049A PL21904979A PL124284B1 PL 124284 B1 PL124284 B1 PL 124284B1 PL 1979219049 A PL1979219049 A PL 1979219049A PL 21904979 A PL21904979 A PL 21904979A PL 124284 B1 PL124284 B1 PL 124284B1
Authority
PL
Poland
Prior art keywords
derivatives
daunorubicin
antibiotics
group
antibiotic
Prior art date
Application number
PL1979219049A
Other languages
English (en)
Polish (pl)
Other versions
PL219049A1 (show.php
Inventor
Barbara Stefanska
Leonard Falkowski
Edward Borowski
Original Assignee
Politechnika Gdanska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Gdanska filed Critical Politechnika Gdanska
Priority to PL1979219049A priority Critical patent/PL124284B1/pl
Priority to SE8005099A priority patent/SE8005099L/xx
Priority to DK305880A priority patent/DK305880A/da
Priority to BE0/201411A priority patent/BE884318A/fr
Priority to GB8023586A priority patent/GB2060609B/en
Priority to SU802949076A priority patent/SU1011051A3/ru
Priority to DE3028148A priority patent/DE3028148C2/de
Priority to FI802332A priority patent/FI67708C/fi
Priority to US06/172,262 priority patent/US4351937A/en
Priority to SU802954187A priority patent/SU1054352A1/ru
Priority to JP55118220A priority patent/JPS5914479B2/ja
Priority to FR8019344A priority patent/FR2473524A1/fr
Publication of PL219049A1 publication Critical patent/PL219049A1/xx
Publication of PL124284B1 publication Critical patent/PL124284B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL1979219049A 1979-10-17 1979-10-17 Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group PL124284B1 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
PL1979219049A PL124284B1 (en) 1979-10-17 1979-10-17 Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group
SE8005099A SE8005099L (sv) 1979-10-17 1980-07-11 N-glykosylderivat av antracyklinantibiotika och sett att framstella dessa
DK305880A DK305880A (da) 1979-10-17 1980-07-15 N-glycosylderivater af antibiotika fra anthracyclongruppen samt fremgangsmaade til deres fremstilling
BE0/201411A BE884318A (fr) 1979-10-17 1980-07-15 Derives n-glycosyliques des antibiotiques du groupe des anthracyclines et leur preparation
GB8023586A GB2060609B (en) 1979-10-17 1980-07-18 N-glycosyl derivatives of anthracyline antibiotics and the method of their preparation
SU802949076A SU1011051A3 (ru) 1979-10-17 1980-07-22 Способ получени @ -гликозиловых производных антибиотиков из группы антрациклинов
DE3028148A DE3028148C2 (de) 1979-10-17 1980-07-24 N-Glykosylderivate von Daunorubicin und Adriamycin, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
FI802332A FI67708C (fi) 1979-10-17 1980-07-24 Foerfarande foer framstaellning av antibiotisk n-glukosylderivat av daunorubicin eller adriamycin
US06/172,262 US4351937A (en) 1979-10-17 1980-07-25 N-Glycosyl derivatives of anthracycline antibiotics and the method of their preparation
SU802954187A SU1054352A1 (ru) 1979-10-17 1980-07-30 N-гликозиловые производные даунорубицина,про вл ющие антибиотическую активность
JP55118220A JPS5914479B2 (ja) 1979-10-17 1980-08-26 アントラサイクリン系抗生物質のｎ−グリコシル誘導体およびその製法
FR8019344A FR2473524A1 (fr) 1979-10-17 1980-09-08 Derives n-glycosyliques des antibiotiques du groupe des anthracyclines et procede pour leur obtention

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL1979219049A PL124284B1 (en) 1979-10-17 1979-10-17 Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group

Publications (2)

Publication Number Publication Date
PL219049A1 PL219049A1 (show.php) 1981-05-08
PL124284B1 true PL124284B1 (en) 1983-01-31

Family

ID=19998972

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1979219049A PL124284B1 (en) 1979-10-17 1979-10-17 Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group

Country Status (11)

Country Link
US (1) US4351937A (show.php)
JP (1) JPS5914479B2 (show.php)
BE (1) BE884318A (show.php)
DE (1) DE3028148C2 (show.php)
DK (1) DK305880A (show.php)
FI (1) FI67708C (show.php)
FR (1) FR2473524A1 (show.php)
GB (1) GB2060609B (show.php)
PL (1) PL124284B1 (show.php)
SE (1) SE8005099L (show.php)
SU (2) SU1011051A3 (show.php)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648327A5 (de) * 1980-10-16 1985-03-15 Hoffmann La Roche Anthracycline.
JPS6297A (ja) * 1985-06-24 1987-01-06 Microbial Chem Res Found アントラサイクリン化合物
US4863739A (en) * 1987-05-19 1989-09-05 Board Of Regents, The University Of Texas System Liposome compositions of anthracycline derivatives
WO1989006654A1 (en) * 1988-01-19 1989-07-27 Board Of Regents, The University Of Texas System Glycosides, liposomal compositions thereof, and methods for their use
EP0648503B1 (en) * 1993-09-22 2000-07-26 Hoechst Aktiengesellschaft Pro-prodrugs, their production and use
GB9727546D0 (en) * 1997-12-31 1998-03-18 Pharmacia & Upjohn Spa Anthracycline glycosides
WO2000056267A2 (en) * 1999-03-19 2000-09-28 Waldemar Priebe Methods and compositions for the manufacture of c-3' and c-4' anthracycline antibiotics
EP1278527A4 (en) 2000-01-14 2003-04-09 Intrabiotics Pharmaceuticals DERIVATIVES OF POLYEN MACROLIDES, THEIR PRODUCTION AND USE
CN104211738B (zh) * 2014-08-15 2016-09-28 合肥合源药业有限公司 一种伊达比星中的杂质、其制备方法及其应用
RU2642068C1 (ru) * 2017-04-26 2018-01-24 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) N-пиперонильные производные даунорубицина, обладающие антипролиферативными свойствами

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60877C (fi) * 1971-08-13 1982-04-13 Politechnika Gdanska Foerfarande foer framstaellning av terapeutiskt aktiva i vatten laett dispergerbara polyenmakrolidantibiot-n-glykosylderivat
JPS5323961A (en) * 1976-08-16 1978-03-06 Microbial Chem Res Found Antitumors
GB1561507A (en) * 1976-11-17 1980-02-20 Farmaceutici Italia Snthracycline disaccharides
GB2007645B (en) * 1977-10-17 1982-05-12 Stanford Res Inst Int Benzyl anthracyclines and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
FR2473524B1 (show.php) 1983-06-03
GB2060609A (en) 1981-05-07
JPS5914479B2 (ja) 1984-04-04
JPS5663994A (en) 1981-05-30
FI67708B (fi) 1985-01-31
SU1011051A3 (ru) 1983-04-07
SE8005099L (sv) 1981-04-18
FR2473524A1 (fr) 1981-07-17
DK305880A (da) 1981-04-18
PL219049A1 (show.php) 1981-05-08
SU1054352A1 (ru) 1983-11-15
DE3028148A1 (de) 1981-04-30
BE884318A (fr) 1980-11-03
US4351937A (en) 1982-09-28
DE3028148C2 (de) 1984-10-25
FI802332A7 (fi) 1981-04-18
FI67708C (fi) 1985-05-10
GB2060609B (en) 1984-09-05

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