PL103751B1 - Sposob wytwarzania nowych pochodnych imidazo/1,2-a/-pirydyn - Google Patents
Sposob wytwarzania nowych pochodnych imidazo/1,2-a/-pirydyn Download PDFInfo
- Publication number
- PL103751B1 PL103751B1 PL1976194238A PL19423876A PL103751B1 PL 103751 B1 PL103751 B1 PL 103751B1 PL 1976194238 A PL1976194238 A PL 1976194238A PL 19423876 A PL19423876 A PL 19423876A PL 103751 B1 PL103751 B1 PL 103751B1
- Authority
- PL
- Poland
- Prior art keywords
- pyridine
- imidazo
- amino
- group
- phenylthio
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/86—Hydrazides; Thio or imino analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63903475A | 1975-12-09 | 1975-12-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL103751B1 true PL103751B1 (pl) | 1979-07-31 |
Family
ID=24562456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1976194238A PL103751B1 (pl) | 1975-12-09 | 1976-12-08 | Sposob wytwarzania nowych pochodnych imidazo/1,2-a/-pirydyn |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4096264A (forum.php) |
| JP (1) | JPS5273896A (forum.php) |
| AR (1) | AR222960A1 (forum.php) |
| AT (1) | AT361475B (forum.php) |
| AU (1) | AU505045B2 (forum.php) |
| BE (1) | BE849123A (forum.php) |
| CA (1) | CA1084930A (forum.php) |
| CH (1) | CH626362A5 (forum.php) |
| DE (1) | DE2655681A1 (forum.php) |
| DK (1) | DK529276A (forum.php) |
| ES (1) | ES453947A1 (forum.php) |
| FI (1) | FI763343A7 (forum.php) |
| FR (1) | FR2334357A1 (forum.php) |
| GB (1) | GB1524589A (forum.php) |
| GR (1) | GR62009B (forum.php) |
| IL (1) | IL51024A (forum.php) |
| NL (1) | NL7613160A (forum.php) |
| NO (1) | NO764025L (forum.php) |
| NZ (1) | NZ182756A (forum.php) |
| OA (1) | OA05506A (forum.php) |
| PH (1) | PH12259A (forum.php) |
| PL (1) | PL103751B1 (forum.php) |
| PT (1) | PT65915B (forum.php) |
| SE (1) | SE430504B (forum.php) |
| ZA (1) | ZA767331B (forum.php) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4105767A (en) * | 1977-03-28 | 1978-08-08 | Merck & Co., Inc. | Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group |
| US4154835A (en) | 1977-10-12 | 1979-05-15 | Merck & Co., Inc. | Anthelmintic imidazo [1,2-a] pyridines |
| US4250174A (en) * | 1979-05-02 | 1981-02-10 | Merck & Co., Inc. | 3-Substituted imidazo [1,2-A] pyridines |
| US4221796A (en) * | 1979-09-19 | 1980-09-09 | E. R. Squibb & Sons, Inc. | Substituted imidazolo-pyridines and method |
| ZA81219B (en) * | 1980-01-23 | 1982-01-27 | Schering Corp | Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them |
| US4507481A (en) * | 1983-07-29 | 1985-03-26 | Pennwalt Corporation | Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines |
| IT1173196B (it) * | 1984-02-02 | 1987-06-18 | Bellon Roger Schoum Rbs Pharma | Composti imidazopiridinici farmacologicamente attivi |
| US5214138A (en) * | 1989-12-20 | 1993-05-25 | Case Western Reserve University | Imidazopyridinium compound and processes for isolating, identifying, and chemically synthesizing same |
| ES2069137T3 (es) * | 1990-07-30 | 1995-05-01 | Takeda Chemical Industries Ltd | Derivados de imidazopiridina y su uso. |
| WO1999059587A1 (en) * | 1998-05-20 | 1999-11-25 | Eli Lilly And Company | Anti-viral compounds |
| US6358971B1 (en) | 1998-05-20 | 2002-03-19 | Eli Lilly And Company | Anti-viral compounds |
| DE10117184A1 (de) * | 2001-04-05 | 2002-10-17 | Gruenenthal Gmbh | Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen |
| DE602005015833D1 (de) * | 2004-03-19 | 2009-09-17 | Warner Lambert Co | Imidazopyridin- und imidazopyrimidin-derivate als antibakterielle mittel |
| ES2343640T3 (es) * | 2004-08-12 | 2010-08-05 | Amgen Inc. | Bisaril-sulfonamidas. |
| AR066845A1 (es) * | 2007-06-05 | 2009-09-16 | Takeda Pharmaceutical | Derivados de triazolopiridina e imidazopiridina una composicion farmaceutica que los comprende y su uso en la preparacion de un medicamento para el tratamiento del cancer |
| US8431608B2 (en) | 2007-08-17 | 2013-04-30 | Icagen Inc. | Heterocycles as potassium channel modulators |
| EP2178373B1 (en) * | 2007-08-17 | 2013-01-23 | Icagen, Inc. | Heterocycles as potassium channel modulators |
| JP5270553B2 (ja) * | 2007-08-23 | 2013-08-21 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
| WO2009028629A1 (ja) * | 2007-08-29 | 2009-03-05 | Takeda Pharmaceutical Company Limited | 複素環化合物およびその用途 |
| EP2444403A1 (en) | 2008-04-18 | 2012-04-25 | Shionogi Co., Ltd. | Heterocyclic compound having inhibitory activity on PI3K |
| WO2009136663A1 (en) * | 2008-05-08 | 2009-11-12 | Takeda Pharmaceutical Company Limited | Fused heterocyclic derivatives and use thereof |
| EP2399921B1 (en) * | 2008-12-01 | 2015-08-12 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
| JO3101B1 (ar) | 2008-12-02 | 2017-09-20 | Takeda Pharmaceuticals Co | مشتقات بنزوثيازول كعوامل مضادة للسرطان |
| ES2608670T3 (es) | 2009-08-17 | 2017-04-12 | Memorial Sloan-Kettering Cancer Center | Derivados de 2-(pirimidin-5-il)-tiopirimidina como moduladores de Hsp70 y Hsc70 para el tratamiento de trastornos proliferativos |
| JP6607870B2 (ja) | 2014-05-13 | 2019-11-20 | メモリアル スローン ケタリング キャンサー センター | Ｈｓｐ７０モジュレーターならびにその作製および使用方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3701780A (en) * | 1970-09-18 | 1972-10-31 | Merck & Co Inc | Imidazo(1,2-a)pyridines |
| JPS5124517B1 (forum.php) * | 1971-03-15 | 1976-07-24 |
-
1976
- 1976-08-26 US US05/718,652 patent/US4096264A/en not_active Expired - Lifetime
- 1976-11-22 FI FI763343A patent/FI763343A7/fi not_active Application Discontinuation
- 1976-11-24 DK DK529276A patent/DK529276A/da not_active Application Discontinuation
- 1976-11-24 SE SE7613128A patent/SE430504B/xx unknown
- 1976-11-25 NO NO764025A patent/NO764025L/no unknown
- 1976-11-25 NL NL7613160A patent/NL7613160A/xx not_active Application Discontinuation
- 1976-11-29 IL IL51024A patent/IL51024A/xx unknown
- 1976-11-29 NZ NZ182756A patent/NZ182756A/xx unknown
- 1976-11-30 AU AU20102/76A patent/AU505045B2/en not_active Expired
- 1976-12-01 AR AR265695A patent/AR222960A1/es active
- 1976-12-01 CH CH1513176A patent/CH626362A5/de not_active IP Right Cessation
- 1976-12-02 PT PT65915A patent/PT65915B/pt unknown
- 1976-12-03 ES ES453947A patent/ES453947A1/es not_active Expired
- 1976-12-06 AT AT901876A patent/AT361475B/de not_active IP Right Cessation
- 1976-12-07 GR GR52346A patent/GR62009B/el unknown
- 1976-12-07 BE BE173014A patent/BE849123A/xx not_active IP Right Cessation
- 1976-12-07 CA CA267,311A patent/CA1084930A/en not_active Expired
- 1976-12-07 FR FR7636779A patent/FR2334357A1/fr active Granted
- 1976-12-07 GB GB51010/76A patent/GB1524589A/en not_active Expired
- 1976-12-07 PH PH19211A patent/PH12259A/en unknown
- 1976-12-08 PL PL1976194238A patent/PL103751B1/pl unknown
- 1976-12-08 ZA ZA00767331A patent/ZA767331B/xx unknown
- 1976-12-08 DE DE19762655681 patent/DE2655681A1/de not_active Ceased
- 1976-12-09 OA OA56008A patent/OA05506A/xx unknown
- 1976-12-09 JP JP51147227A patent/JPS5273896A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| GR62009B (en) | 1979-02-15 |
| NZ182756A (en) | 1979-11-01 |
| SE7613128L (sv) | 1977-06-10 |
| NO764025L (forum.php) | 1977-06-10 |
| PH12259A (en) | 1978-12-12 |
| ATA901876A (de) | 1980-08-15 |
| NL7613160A (nl) | 1977-06-13 |
| PT65915B (en) | 1978-11-07 |
| AR222960A1 (es) | 1981-07-15 |
| AT361475B (de) | 1981-03-10 |
| IL51024A0 (en) | 1977-01-31 |
| GB1524589A (en) | 1978-09-13 |
| BE849123A (fr) | 1977-06-07 |
| AU505045B2 (en) | 1979-11-08 |
| CH626362A5 (forum.php) | 1981-11-13 |
| DE2655681A1 (de) | 1977-06-16 |
| CA1084930A (en) | 1980-09-02 |
| FR2334357A1 (fr) | 1977-07-08 |
| JPS5273896A (en) | 1977-06-21 |
| JPS6126545B2 (forum.php) | 1986-06-20 |
| OA05506A (fr) | 1981-04-30 |
| ES453947A1 (es) | 1978-03-01 |
| ZA767331B (en) | 1978-07-26 |
| IL51024A (en) | 1981-12-31 |
| PT65915A (en) | 1977-01-01 |
| US4096264A (en) | 1978-06-20 |
| DK529276A (da) | 1977-06-10 |
| AU2010276A (en) | 1978-06-08 |
| SE430504B (sv) | 1983-11-21 |
| FR2334357B1 (forum.php) | 1982-10-15 |
| FI763343A7 (forum.php) | 1977-06-10 |
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