PH31056A - Cyclic amino acid derivatives. - Google Patents

Cyclic amino acid derivatives.

Info

Publication number
PH31056A
PH31056A PH49353A PH49353A PH31056A PH 31056 A PH31056 A PH 31056A PH 49353 A PH49353 A PH 49353A PH 49353 A PH49353 A PH 49353A PH 31056 A PH31056 A PH 31056A
Authority
PH
Philippines
Prior art keywords
lower alkyl
compounds
carbocyclic
aryl
cycloalkyl
Prior art date
Application number
PH49353A
Other languages
English (en)
Inventor
Cynthia A Fink
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/153,395 external-priority patent/US5432186A/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of PH31056A publication Critical patent/PH31056A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Hydrogenated Pyridines (AREA)
PH49353A 1993-11-16 1994-11-11 Cyclic amino acid derivatives. PH31056A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/153,395 US5432186A (en) 1993-11-16 1993-11-16 Cyclic amino acid derivatives
US08/263,859 US5506244A (en) 1993-11-16 1994-06-22 Cyclic amino acid derivatives

Publications (1)

Publication Number Publication Date
PH31056A true PH31056A (en) 1998-02-03

Family

ID=26850506

Family Applications (1)

Application Number Title Priority Date Filing Date
PH49353A PH31056A (en) 1993-11-16 1994-11-11 Cyclic amino acid derivatives.

Country Status (19)

Country Link
US (1) US5668158A (fr)
EP (1) EP0655461B1 (fr)
JP (1) JP3647914B2 (fr)
CN (1) CN1058019C (fr)
AT (1) ATE193706T1 (fr)
AU (1) AU687444B2 (fr)
CA (1) CA2135711A1 (fr)
CY (1) CY2234B1 (fr)
DE (1) DE69424846T2 (fr)
DK (1) DK0655461T3 (fr)
ES (1) ES2148305T3 (fr)
FI (1) FI118600B (fr)
GR (1) GR3033829T3 (fr)
HU (1) HU226300B1 (fr)
IL (1) IL111581A (fr)
NO (1) NO311224B1 (fr)
NZ (1) NZ264913A (fr)
PH (1) PH31056A (fr)
PT (1) PT655461E (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1273455B (it) * 1995-01-27 1997-07-08 Zambon Spa Derivati tiolici ad attivita' inibitrice delle metallopeptidasi
JPH08325263A (ja) * 1995-05-31 1996-12-10 Sumitomo Metal Ind Ltd 新規２−アミノ−３−フェニルプロピオン酸誘導体
WO1997011717A1 (fr) * 1995-09-27 1997-04-03 Novartis Ag Traitement de l'insuffisance renale chronique et progressive
US6777550B1 (en) 1996-04-12 2004-08-17 Bristol-Myers Squibb Company N-formyl hydroxylamine containing compounds useful as ACE inhibitors and/or NEP inhibitors
WO1997038705A1 (fr) * 1996-04-12 1997-10-23 Bristol-Myers Squibb Company Composes a base de n-formyl hydroxylamine convenant comme inhibiteurs de l'enzyme ace et/ou de l'endopeptidase nep
US6423727B1 (en) 1998-04-23 2002-07-23 Novartis Ag Certain thiol inhibitors of endothelin-converting enzyme
US6426354B1 (en) 1998-04-23 2002-07-30 Novartis Ag Certain heteroaryl substituted thiol inhibitors of endothelin-converting enzyme
HUP0101640A3 (en) * 1998-04-23 2002-10-28 Novartis Ag Certain thoil inhibitors of endothelin-converting enzyme
CZ20013453A3 (cs) * 1999-03-29 2002-02-13 Bristol-Myers Squibb Company Inhibitor vasopeptidázy a farmaceutický prostředek, který ho obsahuje
US6509330B2 (en) 2000-02-17 2003-01-21 Bristol-Myers Squibb Company Hydroxamic acid containing compounds useful as ACE inhibitors and/or NEP inhibotors
ES2274106T3 (es) * 2001-09-21 2007-05-16 Novartis Ag Derivados de pirano como inhibidores tanto de ace como de nep.
US6919343B2 (en) 2002-02-08 2005-07-19 Merck & Co., Inc. N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives
ATE316954T1 (de) 2002-02-08 2006-02-15 Merck & Co Inc N-biphenylmethylaminocycloalkancarboxamid- derivative
US7045653B2 (en) 2002-12-23 2006-05-16 Pfizer, Inc. Pharmaceuticals
EP2127658A4 (fr) * 2007-01-10 2011-04-27 Kowa Co Agent thérapeutique pour la maladie de ménière
CN105670160A (zh) * 2015-10-12 2016-06-15 陆思烨 一种防紫外抗老化电线电缆料及其制备方法
UY38072A (es) 2018-02-07 2019-10-01 Novartis Ag Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093739A (en) * 1977-06-15 1978-06-06 Mead Johnson & Company Mercaptoacylamidobenzoyl glycine and mucolytic process
GB8820844D0 (en) * 1988-09-05 1988-10-05 Pfizer Ltd Therapeutic agents
GB9004260D0 (en) * 1990-02-26 1990-04-18 Pfizer Ltd Therapeutic agents
FR2679564A1 (fr) * 1991-07-23 1993-01-29 Inst Nat Sante Rech Med Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent.
US5208236A (en) * 1992-09-23 1993-05-04 Schering Corporation N-(acylaminomethyl)glutaryl amino acids and use

Also Published As

Publication number Publication date
HU226300B1 (en) 2008-08-28
HU9403276D0 (en) 1995-01-30
FI945354A (fi) 1995-05-17
CN1107857A (zh) 1995-09-06
FI945354A0 (fi) 1994-11-14
ES2148305T3 (es) 2000-10-16
EP0655461A1 (fr) 1995-05-31
PT655461E (pt) 2000-11-30
EP0655461B1 (fr) 2000-06-07
AU687444B2 (en) 1998-02-26
DE69424846D1 (de) 2000-07-13
US5668158A (en) 1997-09-16
ATE193706T1 (de) 2000-06-15
CA2135711A1 (fr) 1995-05-17
CY2234B1 (en) 2003-04-18
HUT71423A (en) 1995-11-28
FI118600B (fi) 2008-01-15
NO944364L (no) 1995-05-18
AU7772994A (en) 1995-05-25
IL111581A (en) 1999-07-14
CN1058019C (zh) 2000-11-01
NO944364D0 (no) 1994-11-15
DK0655461T3 (da) 2000-10-02
GR3033829T3 (en) 2000-10-31
IL111581A0 (en) 1995-01-24
JPH07196685A (ja) 1995-08-01
DE69424846T2 (de) 2000-11-16
JP3647914B2 (ja) 2005-05-18
NO311224B1 (no) 2001-10-29
NZ264913A (en) 1997-02-24

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