PH30819A - A synthetic signal for the transport of proteins in expression. - Google Patents

A synthetic signal for the transport of proteins in expression.

Info

Publication number
PH30819A
PH30819A PH32879A PH32879A PH30819A PH 30819 A PH30819 A PH 30819A PH 32879 A PH32879 A PH 32879A PH 32879 A PH32879 A PH 32879A PH 30819 A PH30819 A PH 30819A
Authority
PH
Philippines
Prior art keywords
transport
proteins
expression
synthetic signal
incorporation
Prior art date
Application number
PH32879A
Other languages
English (en)
Inventor
Engels Joachim
Uhlmann Eugene
Wetekam Waldemar
Laineweber Michael
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of PH30819A publication Critical patent/PH30819A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • C12N15/625DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
PH32879A 1984-10-06 1985-10-14 A synthetic signal for the transport of proteins in expression. PH30819A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843436818 DE3436818A1 (de) 1984-10-06 1984-10-06 Synthetische signalsequenz zum transport von proteinen in expressionssystemen

Publications (1)

Publication Number Publication Date
PH30819A true PH30819A (en) 1997-10-17

Family

ID=6247347

Family Applications (1)

Application Number Title Priority Date Filing Date
PH32879A PH30819A (en) 1984-10-06 1985-10-14 A synthetic signal for the transport of proteins in expression.

Country Status (15)

Country Link
EP (1) EP0177827B1 (pt)
JP (1) JPS6188883A (pt)
AT (1) ATE97445T1 (pt)
AU (1) AU595486B2 (pt)
CA (1) CA1340280C (pt)
DE (2) DE3436818A1 (pt)
DK (1) DK175511B1 (pt)
ES (1) ES8605579A1 (pt)
GR (1) GR852405B (pt)
HU (1) HU197355B (pt)
IE (1) IE63262B1 (pt)
IL (1) IL76573A (pt)
NZ (1) NZ213717A (pt)
PH (1) PH30819A (pt)
PT (1) PT81253B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0196864A3 (en) * 1985-03-25 1988-03-23 Cetus Corporation Alkaline phosphatase-mediated processing and secretion of recombinant proteins, dna sequences for use therein and cells transformed using such sequences
IT1196484B (it) * 1986-07-11 1988-11-16 Sclavo Spa Vettore ad espressione e secrezione in lieviti,utile per la preparazione di proteine eterologhe
US5426036A (en) * 1987-05-05 1995-06-20 Hoechst Aktiengesellschaft Processes for the preparation of foreign proteins in streptomycetes
EP0333215B1 (en) * 1988-03-18 1994-08-31 Wang Laboratories Inc. Distributed reference and change table for a virtual memory system
JP4634371B2 (ja) 2003-03-27 2011-02-16 ピーティーシー セラピューティクス,インコーポレーテッド tRNAスプライシングエンドヌクレアーゼに標的化する化合物の同定方法、および該化合物の抗増殖剤としての使用
CA2520510A1 (en) 2003-03-27 2004-10-14 Ptc Therapeutics, Inc. Methods of identifying compounds that target trna splicing endonuclease and uses of said compounds as anti-fungal agents
DE04777457T1 (de) 2003-07-02 2008-08-14 Ptc Therapeutics, Inc. Rna prozessierende proteinkomplexe und verwendungen davon

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5939899A (ja) * 1982-08-27 1984-03-05 Gakuzo Tamura 新規ベクタ−
US4711844A (en) * 1983-03-09 1987-12-08 Cetus Corporation Modified signal peptides
NZ207925A (en) * 1983-04-25 1988-05-30 Genentech Inc Yeast expression vehicle consisting of a yeast promoter and signal peptide encoding region linked to a heterologus peptide coding region; expression and culture
US4663280A (en) * 1983-05-19 1987-05-05 Public Health Research Institute Of The City Of New York Expression and secretion vectors and method of constructing vectors
AU3011684A (en) * 1983-05-19 1984-12-04 Public Health Research Institute Of The City Of New York, Inc., The Expression and secretion vectors & method of constructing vectors
JPS6030687A (ja) * 1983-08-01 1985-02-16 Wakunaga Seiyaku Kk Dνa遺伝子,その製造法およびそれを含むプラスミド
EP0170266B1 (en) * 1984-07-30 1993-03-24 Wakunaga Seiyaku Kabushiki Kaisha Process for producing protein, and vector, recombinant dna and transformant used therefor

Also Published As

Publication number Publication date
DE3587660D1 (de) 1993-12-23
IE63262B1 (en) 1995-04-05
EP0177827A2 (de) 1986-04-16
JPS6188883A (ja) 1986-05-07
AU595486B2 (en) 1990-04-05
IE852440L (en) 1986-04-06
PT81253A (de) 1985-11-01
HUT40164A (en) 1986-11-28
ES547600A0 (es) 1986-03-16
DE3436818A1 (de) 1986-04-10
IL76573A0 (en) 1986-02-28
NZ213717A (en) 1989-01-06
DK453285A (da) 1986-04-07
CA1340280C (en) 1998-12-22
DK175511B1 (da) 2004-11-15
HU197355B (en) 1989-03-28
EP0177827A3 (en) 1987-12-02
ES8605579A1 (es) 1986-03-16
IL76573A (en) 1992-06-21
AU4833385A (en) 1986-04-10
DK453285D0 (da) 1985-10-04
ATE97445T1 (de) 1993-12-15
GR852405B (pt) 1986-02-04
PT81253B (pt) 1987-11-30
EP0177827B1 (de) 1993-11-18

Similar Documents

Publication Publication Date Title
AU573523B2 (en) Functional human urokinase proteins
OA08947A (en) Mammalian interleukin-4.
IL87366A0 (en) Nucleic acid and methods for the synthesis of novel fusion polypeptides
ATE44768T1 (de) Verfahren zur mikrobiologischen herstellung von menschlichem serum-albumin.
FI864654A (fi) Menetelmä modifioidun ihmisen t-PA-proteiinin valmistamiseksi
DE3677685D1 (de) Signalkodierungsverfahren und zur ausfuehrung dieses verfahrens.
PH30819A (en) A synthetic signal for the transport of proteins in expression.
EP0149241A3 (en) Dna base sequence containing regions involved in the production and secretion of a protein, recombinant dna including the whole or a part of the dna base sequence, and method of producing proteins by use of the recombinant dna
AU7883887A (en) Synthetic genes encoding proteins from plasmid containing eucaryotic secretory signal peptides and process for secreting encoded proteins
GB2236107B (en) Natural rubber serum concentrate and method of making the same
CS144487A2 (en) Method of coarse protein's content increase
GB8708531D0 (en) Fusion proteins & particles
IL82771A0 (en) Labeling of proteins
RO90275A2 (ro) Procedeu de proteinizare a unor materiale vegetale utilizate ca furaje