PH26714A - Novel human TNF polypeptide mutants and DNAs encoding said mutants - Google Patents
Novel human TNF polypeptide mutants and DNAs encoding said mutants Download PDFInfo
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- PH26714A PH26714A PH35431A PH35431A PH26714A PH 26714 A PH26714 A PH 26714A PH 35431 A PH35431 A PH 35431A PH 35431 A PH35431 A PH 35431A PH 26714 A PH26714 A PH 26714A
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- Philippines
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- tnf
- polypeptide
- replaced
- leu
- pro
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14557586 | 1986-06-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH26714A true PH26714A (en) | 1992-09-15 |
Family
ID=15388278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH35431A PH26714A (en) | 1986-06-20 | 1987-07-19 | Novel human TNF polypeptide mutants and DNAs encoding said mutants |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4990455A (ko) |
| EP (1) | EP0251037B1 (ko) |
| KR (1) | KR880000471A (ko) |
| AT (1) | ATE107362T1 (ko) |
| AU (1) | AU592196B2 (ko) |
| DE (1) | DE3750056T2 (ko) |
| DK (1) | DK312387A (ko) |
| HU (1) | HU210118B (ko) |
| PH (1) | PH26714A (ko) |
| SU (1) | SU1762761A3 (ko) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5081021A (en) * | 1986-02-04 | 1992-01-14 | Mizuno Den Ichi | DNA encoding HTNF variants exhibiting enhanced activity |
| DE3716513A1 (de) * | 1987-05-16 | 1988-11-24 | Basf Ag | Proteine mit tnf-wirkung |
| DE3837012A1 (de) * | 1988-01-15 | 1989-07-27 | Knoll Ag | Verwendung von tnf und lt zur herstellung von arzneimitteln |
| JPH0797997B2 (ja) * | 1988-04-28 | 1995-10-25 | 帝人株式会社 | 新規生理活性ポリペプチド |
| DE3843534A1 (de) * | 1988-12-23 | 1990-07-12 | Basf Ag | Neue tnf-polypeptide |
| DE3922089A1 (de) * | 1989-05-09 | 1990-12-13 | Basf Ag | Neue proteine und ihre herstellung |
| US6262239B1 (en) * | 1989-05-18 | 2001-07-17 | Yeda Research And Development Co., Ltd. | TNF receptor-specific antibodies |
| US6232446B1 (en) * | 1989-05-18 | 2001-05-15 | Yeda Research And Development Co. Ltd. | TNF ligands |
| CA2067821A1 (en) * | 1989-10-24 | 1991-04-25 | Cetus Oncology Corporation | Infective drug delivery system using recombinant retroviral vectors |
| US5519119A (en) * | 1990-09-21 | 1996-05-21 | Ishihara Sangyo Kaisha Ltd. | Muteins of TNF pharmaceutical compositions and a method of making |
| US5653974A (en) * | 1990-10-18 | 1997-08-05 | Board Of Regents,The University Of Texas System | Preparation and characterization of liposomal formulations of tumor necrosis factor |
| CA2055168A1 (en) * | 1990-11-21 | 1992-05-22 | Walter Fiers | Tnf-muteins |
| KR970005042B1 (ko) * | 1993-02-09 | 1997-04-11 | 한일합성섬유공업 주식회사 | 종양괴사인자-알파 뮤테인 |
| CA2119089A1 (en) * | 1993-03-29 | 1994-09-30 | David Banner | Tumor necrosis factor muteins |
| US5888814A (en) * | 1994-06-06 | 1999-03-30 | Chiron Corporation | Recombinant host cells encoding TNF proteins |
| US6184344B1 (en) * | 1995-05-04 | 2001-02-06 | The Scripps Research Institute | Synthesis of proteins by native chemical ligation |
| US7070771B1 (en) | 1996-12-09 | 2006-07-04 | Regents Of The University Of California | Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells |
| HUP0001930A3 (en) * | 1997-04-15 | 2001-10-29 | Pharmexa As | Modified tnfalpha molecules, dna encoding such modified tnfalpha molecules and vaccines comprising such modified tnfalpha molecules and dna |
| US7687461B2 (en) | 2000-03-02 | 2010-03-30 | Xencor, Inc. | Treatment of TNF-α related disorders with TNF-α variant proteins |
| US7056695B2 (en) | 2000-03-02 | 2006-06-06 | Xencor | TNF-α variants |
| US20070172449A1 (en) * | 2000-03-02 | 2007-07-26 | Xencor, Inc. | TNF-alpha VARIANT FORMULATIONS FOR THE TREATMENT OF TNF-alpha RELATED DISORDERS |
| US7244823B2 (en) * | 2000-03-02 | 2007-07-17 | Xencor | TNF-alpha variants proteins for the treatment of TNF-alpha related disorders |
| US7446174B2 (en) | 2001-03-02 | 2008-11-04 | Xencor, Inc. | Protein based TNF-α variants for the treatment of TNF-α related disorders |
| US7101974B2 (en) | 2000-03-02 | 2006-09-05 | Xencor | TNF-αvariants |
| US7662367B2 (en) | 2000-03-02 | 2010-02-16 | Xencor, Inc. | Pharmaceutical compositions for the treatment of TNF-α related disorders |
| US7786282B2 (en) * | 2001-12-06 | 2010-08-31 | The Regents Of The University Of California | Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain |
| KR100475403B1 (ko) * | 2002-05-28 | 2005-03-15 | 재단법인서울대학교산학협력재단 | 반도체 배선용 구리 박막 형성방법 |
| CA2508375C (en) * | 2002-12-02 | 2014-05-27 | Abgenix, Inc. | Antibodies directed to tumor necrosis factor and uses thereof |
| DK2953634T3 (da) | 2013-02-07 | 2021-08-30 | Massachusetts Gen Hospital | Fremgangsmåder til udvidelse eller udtømning af regulerende t-celler |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3723249A (en) * | 1970-02-21 | 1973-03-27 | Ajinomoto Kk | Method of producing l-arginine by microorganism |
| JPS6066989A (ja) * | 1983-09-24 | 1985-04-17 | Kyowa Hakko Kogyo Co Ltd | Ｌ−アルギニンの製造法 |
| EP0155549B1 (en) * | 1984-03-06 | 1991-03-20 | Dainippon Pharmaceutical Co., Ltd. | Dna encoding human tumor necrosis factor and human tumor necrosis factor polypeptide |
| GR851626B (ko) * | 1984-07-05 | 1985-11-26 | Genentech Inc | |
| AU589919B2 (en) * | 1984-10-15 | 1989-10-26 | Cetus Corp | Human tumor necrosis factor |
| EP0205038A1 (en) * | 1985-05-29 | 1986-12-17 | Suntory Limited | Polypeptide, process for preparing it, microorganism and pharmaceutical use |
-
1987
- 1987-06-16 DE DE3750056T patent/DE3750056T2/de not_active Expired - Fee Related
- 1987-06-16 EP EP87108709A patent/EP0251037B1/en not_active Expired - Lifetime
- 1987-06-16 AT AT87108709T patent/ATE107362T1/de not_active IP Right Cessation
- 1987-06-19 SU SU874202872A patent/SU1762761A3/ru active
- 1987-06-19 DK DK312387A patent/DK312387A/da not_active Application Discontinuation
- 1987-06-19 HU HU872805A patent/HU210118B/hu not_active IP Right Cessation
- 1987-06-19 AU AU74508/87A patent/AU592196B2/en not_active Ceased
- 1987-06-20 KR KR1019870006259A patent/KR880000471A/ko not_active Application Discontinuation
- 1987-06-22 US US07/064,609 patent/US4990455A/en not_active Expired - Fee Related
- 1987-07-19 PH PH35431A patent/PH26714A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4990455A (en) | 1991-02-05 |
| HUT46065A (en) | 1988-09-28 |
| SU1762761A3 (ru) | 1992-09-15 |
| DK312387A (da) | 1987-12-21 |
| DE3750056T2 (de) | 1995-04-06 |
| ATE107362T1 (de) | 1994-07-15 |
| AU592196B2 (en) | 1990-01-04 |
| EP0251037B1 (en) | 1994-06-15 |
| EP0251037A3 (en) | 1988-12-07 |
| AU7450887A (en) | 1988-01-07 |
| EP0251037A2 (en) | 1988-01-07 |
| KR880000471A (ko) | 1988-03-26 |
| DE3750056D1 (de) | 1994-07-21 |
| DK312387D0 (da) | 1987-06-19 |
| HU210118B (en) | 1995-02-28 |
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