PH23937A - Anxiolytic-n-(1-azabicyclo(2.2.2.)oct-3-yl)benzamides and thiobenzamides - Google Patents

Anxiolytic-n-(1-azabicyclo(2.2.2.)oct-3-yl)benzamides and thiobenzamides

Info

Publication number
PH23937A
PH23937A PH36199A PH36199A PH23937A PH 23937 A PH23937 A PH 23937A PH 36199 A PH36199 A PH 36199A PH 36199 A PH36199 A PH 36199A PH 23937 A PH23937 A PH 23937A
Authority
PH
Philippines
Prior art keywords
thiobenzamides
benzamides
anxiolytic
azabicyclo
oct
Prior art date
Application number
PH36199A
Other languages
English (en)
Inventor
Robert John Naylor
Brenda Naylor
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868629962A external-priority patent/GB8629962D0/en
Priority claimed from GB878709508A external-priority patent/GB8709508D0/en
Priority claimed from GB878717050A external-priority patent/GB8717050D0/en
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of PH23937A publication Critical patent/PH23937A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH36199A 1986-12-16 1987-12-10 Anxiolytic-n-(1-azabicyclo(2.2.2.)oct-3-yl)benzamides and thiobenzamides PH23937A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB868629962A GB8629962D0 (en) 1986-12-16 1986-12-16 Benzamides & thiobenzamides
GB878709508A GB8709508D0 (en) 1987-04-22 1987-04-22 Benzamides & thiobenzamides
GB878717050A GB8717050D0 (en) 1987-07-20 1987-07-20 Benzamides & thiobenzamides

Publications (1)

Publication Number Publication Date
PH23937A true PH23937A (en) 1990-01-23

Family

ID=27263251

Family Applications (1)

Application Number Title Priority Date Filing Date
PH36199A PH23937A (en) 1986-12-16 1987-12-10 Anxiolytic-n-(1-azabicyclo(2.2.2.)oct-3-yl)benzamides and thiobenzamides

Country Status (12)

Country Link
US (1) US4908370A (ja)
EP (1) EP0272052B1 (ja)
AU (1) AU608793B2 (ja)
CA (1) CA1309660C (ja)
DE (1) DE3780276T2 (ja)
DK (1) DK658687A (ja)
ES (1) ES2051753T3 (ja)
GR (1) GR3005667T3 (ja)
IL (1) IL84834A0 (ja)
NZ (1) NZ222931A (ja)
PH (1) PH23937A (ja)
PT (1) PT86362B (ja)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3689974T2 (de) * 1985-03-14 1994-11-03 Beecham Group Plc Arzneimittel zur Behandlung von Emesis.
US5198447A (en) * 1986-11-21 1993-03-30 Glaxo Group Limited Medicaments
GB8627909D0 (en) * 1986-11-21 1986-12-31 Glaxo Group Ltd Medicaments
DE3777805D1 (de) * 1986-11-21 1992-04-30 Glaxo Group Ltd Arzneimittel zur behandlung oder vorbeugung des entzugssyndromes.
US5246941A (en) * 1986-12-17 1993-09-21 Glaxo Group Limited Method for the treatment of depression
GB8720805D0 (en) * 1987-09-04 1987-10-14 Naylor R J 2-alkoxy-n-(1-azabicyclo(2 2 2)oct-3-yl)benzamides & thiobenzamides
EP0311724A1 (en) * 1987-10-16 1989-04-19 Synthelabo Anxiolytic-R-N-(1-azabicyclo[2.2.2]oct-3-yl) benzamides and thiobenzamides
EP0353372B1 (en) * 1988-08-04 1993-02-03 Synthelabo Antischizophrenic-S-N-(1-azabicyclo[2.2.2.]oct-3-yl) benzamides and thiobenzamides
GB8820650D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
MX18467A (es) * 1988-11-23 1993-07-01 Pfizer Agentes terapeuticos de quinuclidinas
AU631632B2 (en) * 1989-04-21 1992-12-03 Novartis Ag Therapeutic use of 5-ht3 receptor antagonists
WO1992016239A1 (en) * 1991-03-13 1992-10-01 The Regents Of The University Of Minnesota Radiopharmaceutical agents for the detection of alzheimer's disease
US5273972A (en) * 1992-03-26 1993-12-28 A. H. Robins Company, Incorporated [(2-diakylaminomethyl)-3-quinuclidinyl]-benzamides and benzoates
US5837711A (en) * 1992-10-28 1998-11-17 Pfizer Inc. Substituted quinuclidines as substance P antagonists
US5574028A (en) * 1994-10-31 1996-11-12 Eli Lilly And Company Method for treating anxiety
WO2002016357A2 (en) 2000-08-18 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
AU2001282874A1 (en) 2000-08-18 2002-03-04 Pharmacia And Upjohn Company Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
PE20021019A1 (es) 2001-04-19 2002-11-13 Upjohn Co Grupos azabiciclicos sustituidos
MXPA04000779A (es) * 2001-08-24 2004-04-20 Pharmacia & Up John Company 7-aza[2.2.1]bicicloheptanos sustituidos con arilo para el tratamiento de enfermedades.
MXPA04007936A (es) 2002-02-15 2004-11-26 Upjohn Co Compuestos de aril-sustituidos para el tratamiento de enfermedades.
MXPA04007083A (es) * 2002-02-20 2004-10-29 Upjohn Co Compuestos azabiciclicos para el tratamiento de enfermedades.
FR2861076B1 (fr) * 2003-10-17 2006-01-06 Sanofi Synthelabo Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique
JP5775819B2 (ja) 2008-10-09 2015-09-09 ハワード ヒューズ メディカル インスティチュート 新規なキメラリガンド開口型イオンチャネルおよびその使用方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2548968A1 (de) * 1975-11-03 1977-05-12 Thomae Gmbh Dr K Neue amino-benzoesaeureamide
US4093734A (en) * 1975-11-03 1978-06-06 Boehringer Ingelheim Gmbh Amino-benzoic acid amides
AU532065B2 (en) * 1979-06-08 1983-09-15 Philip Morris Products Inc. Optical perforating apparatus
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
US4593034A (en) * 1984-04-06 1986-06-03 A. H. Robins Company, Inc. 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides
US4605652A (en) * 1985-02-04 1986-08-12 A. H. Robins Company, Inc. Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes
US4870181A (en) * 1985-02-04 1989-09-26 A. H. Robins Company, Incorporated Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2])octan-3-yl)aminobenzamides
DE3689974T2 (de) * 1985-03-14 1994-11-03 Beecham Group Plc Arzneimittel zur Behandlung von Emesis.
GB8511988D0 (en) * 1985-05-11 1985-06-19 Beecham Group Plc Compounds

Also Published As

Publication number Publication date
DE3780276D1 (de) 1992-08-13
CA1309660C (en) 1992-11-03
DE3780276T2 (de) 1993-02-25
DK658687D0 (da) 1987-12-15
AU8254687A (en) 1988-06-16
ES2051753T3 (es) 1994-07-01
EP0272052A1 (en) 1988-06-22
US4908370A (en) 1990-03-13
AU608793B2 (en) 1991-04-18
PT86362B (pt) 1990-11-07
GR3005667T3 (ja) 1993-06-07
NZ222931A (en) 1991-08-27
EP0272052B1 (en) 1992-07-08
PT86362A (en) 1988-01-01
IL84834A0 (en) 1988-06-30
DK658687A (da) 1988-06-17

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