DE3780276D1 - Angstloesende n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide und -thiobenzamide. - Google Patents
Angstloesende n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide und -thiobenzamide.Info
- Publication number
- DE3780276D1 DE3780276D1 DE8787310859T DE3780276T DE3780276D1 DE 3780276 D1 DE3780276 D1 DE 3780276D1 DE 8787310859 T DE8787310859 T DE 8787310859T DE 3780276 T DE3780276 T DE 3780276T DE 3780276 D1 DE3780276 D1 DE 3780276D1
- Authority
- DE
- Germany
- Prior art keywords
- thiobenzamides
- benzamides
- azabicyclo
- relaxing
- oct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868629962A GB8629962D0 (en) | 1986-12-16 | 1986-12-16 | Benzamides & thiobenzamides |
GB878709508A GB8709508D0 (en) | 1987-04-22 | 1987-04-22 | Benzamides & thiobenzamides |
GB878717050A GB8717050D0 (en) | 1987-07-20 | 1987-07-20 | Benzamides & thiobenzamides |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3780276D1 true DE3780276D1 (de) | 1992-08-13 |
DE3780276T2 DE3780276T2 (de) | 1993-02-25 |
Family
ID=27263251
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8787310859T Expired - Fee Related DE3780276T2 (de) | 1986-12-16 | 1987-12-10 | Angstloesende n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide und -thiobenzamide. |
Country Status (12)
Country | Link |
---|---|
US (1) | US4908370A (de) |
EP (1) | EP0272052B1 (de) |
AU (1) | AU608793B2 (de) |
CA (1) | CA1309660C (de) |
DE (1) | DE3780276T2 (de) |
DK (1) | DK658687A (de) |
ES (1) | ES2051753T3 (de) |
GR (1) | GR3005667T3 (de) |
IL (1) | IL84834A0 (de) |
NZ (1) | NZ222931A (de) |
PH (1) | PH23937A (de) |
PT (1) | PT86362B (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE385517T1 (de) * | 1985-03-14 | 1991-07-25 | Beecham Group p.l.c., Brentford, Middlesex | Arzneimittel zur behandlung von erbrechen. |
GB8627909D0 (en) * | 1986-11-21 | 1986-12-31 | Glaxo Group Ltd | Medicaments |
US4948803A (en) * | 1986-11-21 | 1990-08-14 | Glaxo Group Limited | Medicaments for treatment on prevention of withdrawal syndrome |
US5198447A (en) * | 1986-11-21 | 1993-03-30 | Glaxo Group Limited | Medicaments |
US5246941A (en) * | 1986-12-17 | 1993-09-21 | Glaxo Group Limited | Method for the treatment of depression |
GB8720805D0 (en) * | 1987-09-04 | 1987-10-14 | Naylor R J | 2-alkoxy-n-(1-azabicyclo(2 2 2)oct-3-yl)benzamides & thiobenzamides |
EP0311724A1 (de) * | 1987-10-16 | 1989-04-19 | Synthelabo | Anxiolytische R-N-(1-Azabicyclo[2.2.2]oct-3-yl)-benzamide und -thiobenzamide |
ATE85217T1 (de) * | 1988-08-04 | 1993-02-15 | Synthelabo | Antischizophren-wirksame s-n-(1-azabicyclo (2.2.2.>oct-3-yl)benzamide und thiobenzamide. |
GB8820650D0 (en) * | 1988-09-01 | 1988-10-05 | Glaxo Group Ltd | Medicaments |
MX18467A (es) * | 1988-11-23 | 1993-07-01 | Pfizer | Agentes terapeuticos de quinuclidinas |
ES2061024T3 (es) * | 1989-04-21 | 1994-12-01 | Sandoz Ag | Uso terapeutico de antagonistas de receptores de 5-ht3. |
EP0576611A4 (en) * | 1991-03-13 | 1996-01-24 | Univ Minnesota | Radiopharmaceutical agents for the detection of alzheimer's disease |
US5273972A (en) * | 1992-03-26 | 1993-12-28 | A. H. Robins Company, Incorporated | [(2-diakylaminomethyl)-3-quinuclidinyl]-benzamides and benzoates |
US5837711A (en) * | 1992-10-28 | 1998-11-17 | Pfizer Inc. | Substituted quinuclidines as substance P antagonists |
US5574028A (en) * | 1994-10-31 | 1996-11-12 | Eli Lilly And Company | Method for treating anxiety |
AU2001282873A1 (en) | 2000-08-18 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted aryl compounds for treatment of disease |
AU2001282874A1 (en) | 2000-08-18 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands) |
PE20021019A1 (es) | 2001-04-19 | 2002-11-13 | Upjohn Co | Grupos azabiciclicos sustituidos |
CA2455773A1 (en) * | 2001-08-24 | 2003-03-06 | Pharmacia & Upjohn Company | Substituted-aryl 7-aza¬2.2.1|bicycloheptanes for the treatment of disease |
US6852716B2 (en) | 2002-02-15 | 2005-02-08 | Pfizer Inc | Substituted-aryl compounds for treatment of disease |
WO2003072578A1 (en) * | 2002-02-20 | 2003-09-04 | Pharmacia & Upjohn Company | Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity |
FR2861076B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique |
WO2010042799A2 (en) | 2008-10-09 | 2010-04-15 | Howard Hughes Medical Institute | Novel chimeric ligand-gated ion channels and methods of use thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2548968A1 (de) * | 1975-11-03 | 1977-05-12 | Thomae Gmbh Dr K | Neue amino-benzoesaeureamide |
US4093734A (en) * | 1975-11-03 | 1978-06-06 | Boehringer Ingelheim Gmbh | Amino-benzoic acid amides |
AU532065B2 (en) * | 1979-06-08 | 1983-09-15 | Philip Morris Products Inc. | Optical perforating apparatus |
FR2531083B1 (fr) * | 1982-06-29 | 1986-11-28 | Sandoz Sa | Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments |
FR2529548A1 (fr) * | 1982-07-02 | 1984-01-06 | Delalande Sa | Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique |
US4593034A (en) * | 1984-04-06 | 1986-06-03 | A. H. Robins Company, Inc. | 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides |
US4605652A (en) * | 1985-02-04 | 1986-08-12 | A. H. Robins Company, Inc. | Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes |
US4870181A (en) * | 1985-02-04 | 1989-09-26 | A. H. Robins Company, Incorporated | Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2])octan-3-yl)aminobenzamides |
DE385517T1 (de) * | 1985-03-14 | 1991-07-25 | Beecham Group p.l.c., Brentford, Middlesex | Arzneimittel zur behandlung von erbrechen. |
GB8511988D0 (en) * | 1985-05-11 | 1985-06-19 | Beecham Group Plc | Compounds |
-
1987
- 1987-12-10 EP EP87310859A patent/EP0272052B1/de not_active Expired
- 1987-12-10 ES ES87310859T patent/ES2051753T3/es not_active Expired - Lifetime
- 1987-12-10 DE DE8787310859T patent/DE3780276T2/de not_active Expired - Fee Related
- 1987-12-10 PH PH36199A patent/PH23937A/en unknown
- 1987-12-15 US US07/133,410 patent/US4908370A/en not_active Expired - Fee Related
- 1987-12-15 IL IL84834A patent/IL84834A0/xx unknown
- 1987-12-15 CA CA000554310A patent/CA1309660C/en not_active Expired - Fee Related
- 1987-12-15 AU AU82546/87A patent/AU608793B2/en not_active Ceased
- 1987-12-15 PT PT86362A patent/PT86362B/pt not_active IP Right Cessation
- 1987-12-15 NZ NZ222931A patent/NZ222931A/xx unknown
- 1987-12-15 DK DK658687A patent/DK658687A/da not_active Application Discontinuation
-
1992
- 1992-09-10 GR GR920401990T patent/GR3005667T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA1309660C (en) | 1992-11-03 |
DE3780276T2 (de) | 1993-02-25 |
PT86362B (pt) | 1990-11-07 |
AU8254687A (en) | 1988-06-16 |
PT86362A (en) | 1988-01-01 |
NZ222931A (en) | 1991-08-27 |
DK658687D0 (da) | 1987-12-15 |
ES2051753T3 (es) | 1994-07-01 |
AU608793B2 (en) | 1991-04-18 |
US4908370A (en) | 1990-03-13 |
GR3005667T3 (de) | 1993-06-07 |
EP0272052A1 (de) | 1988-06-22 |
EP0272052B1 (de) | 1992-07-08 |
PH23937A (en) | 1990-01-23 |
IL84834A0 (en) | 1988-06-30 |
DK658687A (da) | 1988-06-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |