PH22851A - Pyrrolidone derivatives - Google Patents

Pyrrolidone derivatives

Info

Publication number
PH22851A
PH22851A PH33922A PH33922A PH22851A PH 22851 A PH22851 A PH 22851A PH 33922 A PH33922 A PH 33922A PH 33922 A PH33922 A PH 33922A PH 22851 A PH22851 A PH 22851A
Authority
PH
Philippines
Prior art keywords
pyrrolidone derivatives
branched
alkyl
hydrogen
straight
Prior art date
Application number
PH33922A
Other languages
English (en)
Inventor
Pinza Mario
Pfeiffer Ugo
Banfi Silvano
Farina Carlo
Original Assignee
Isf Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isf Spa filed Critical Isf Spa
Publication of PH22851A publication Critical patent/PH22851A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PH33922A 1985-06-21 1986-06-20 Pyrrolidone derivatives PH22851A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21234/85A IT1190378B (it) 1985-06-21 1985-06-21 Derivati pirrolidonici

Publications (1)

Publication Number Publication Date
PH22851A true PH22851A (en) 1989-01-19

Family

ID=11178795

Family Applications (1)

Application Number Title Priority Date Filing Date
PH33922A PH22851A (en) 1985-06-21 1986-06-20 Pyrrolidone derivatives

Country Status (20)

Country Link
US (1) US4824861A (sv)
EP (1) EP0207681B1 (sv)
JP (1) JPS62461A (sv)
KR (1) KR930006766B1 (sv)
AT (1) ATE73821T1 (sv)
AU (1) AU587258B2 (sv)
CA (1) CA1284248C (sv)
DE (1) DE3684368D1 (sv)
DK (1) DK290286A (sv)
ES (2) ES8800164A1 (sv)
FI (1) FI82446C (sv)
GR (1) GR861577B (sv)
HU (1) HU196225B (sv)
IL (1) IL79136A (sv)
IT (1) IT1190378B (sv)
NO (1) NO168428C (sv)
NZ (1) NZ216550A (sv)
PH (1) PH22851A (sv)
PT (2) PT82815B (sv)
ZA (1) ZA864444B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209644B (it) * 1985-06-21 1989-08-30 Isf Spa Composti farmacologicamente attivi.
DK356288A (da) * 1987-07-30 1989-01-31 Lonza Ag Fremgangsmaade til fremstilling af n-((4-hydroxy-pyrrolidin-2-on-1-yl)-acetyl)-glycinamid
CA2007732A1 (en) * 1989-01-17 1990-07-17 Gary L. Olson Cyclohexaneacetamide derivatives
CH680293A5 (sv) * 1990-06-26 1992-07-31 Lonza Ag
US6229011B1 (en) * 1997-08-22 2001-05-08 Hoffman-La Roche Inc. N-aroylphenylalanine derivative VCAM-1 inhibitors
NZ513254A (en) 1999-02-18 2003-10-31 F Thioamide derivatives
ATE264835T1 (de) 1999-02-18 2004-05-15 Hoffmann La Roche Phenylalaninolderivate
WO2009145839A1 (en) * 2008-04-04 2009-12-03 Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Polyamine compounds that bind tar rna of hiv and methods of treating viral disorders
CN101914052B (zh) * 2010-08-02 2012-06-27 胡建荣 一种奥拉西坦化合物的制备方法
CN102351770B (zh) * 2011-08-12 2012-07-04 江西新先锋医药有限公司 一种奥拉西坦化合物及其药物组合物
CN112724062B (zh) * 2021-01-19 2022-03-15 江苏诚信药业有限公司 一种奥拉西坦杂质b的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH470396A (de) * 1963-08-12 1969-03-31 Hoffmann La Roche Verfahren zur Herstellung von 4-Imidazolidon-Verbindungen
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
YU39660B (en) * 1976-01-14 1985-03-20 Pliva Pharm & Chem Works Process for obtaining 2-oxo-1-pyrrolidine acetamide
AT360980B (de) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works Verfahren zur herstellung von n-alkylamiden des 2-oxo-1-pyrrolidins
GB1539817A (en) * 1976-10-22 1979-02-07 Ucb Sa N-substituted lactams
IT1075564B (it) * 1977-02-11 1985-04-22 Isf Spa Procedimento per la preparazione di derivati pirrolidinici
IT1141287B (it) * 1979-06-13 1986-10-01 Nattermann A & Cie Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
FI840261A (fi) * 1983-01-27 1984-07-28 Ciba Geigy Ag Substituerade pyrrolidinonderivat och foerfarande foer deras framstaellning.
IT1209644B (it) * 1985-06-21 1989-08-30 Isf Spa Composti farmacologicamente attivi.
JPH0681502B2 (ja) * 1988-07-14 1994-10-12 富士通電装株式会社 並列運転保護回路

Also Published As

Publication number Publication date
JPS62461A (ja) 1987-01-06
ES556353A0 (es) 1987-11-01
US4824861A (en) 1989-04-25
NO168428B (no) 1991-11-11
EP0207681A2 (en) 1987-01-07
IT1190378B (it) 1988-02-16
ES8801201A1 (es) 1988-01-01
PT82813A (en) 1986-07-01
EP0207681B1 (en) 1992-03-18
NO862486D0 (no) 1986-06-20
NO862486L (no) 1986-12-22
HU196225B (en) 1988-10-28
ES556351A0 (es) 1988-01-01
KR870000294A (ko) 1987-02-17
NZ216550A (en) 1990-02-26
GR861577B (en) 1986-10-21
KR930006766B1 (ko) 1993-07-23
PT82815A (en) 1986-07-01
CA1284248C (en) 1991-05-14
ATE73821T1 (de) 1992-04-15
FI82446B (fi) 1990-11-30
IT8521234A0 (it) 1985-06-21
DK290286D0 (da) 1986-06-20
FI82446C (sv) 1991-03-11
AU587258B2 (en) 1989-08-10
ES8800164A1 (es) 1987-11-01
FI862420A (fi) 1986-12-22
HUT43815A (en) 1987-12-28
IL79136A (en) 1991-07-18
FI862420A0 (fi) 1986-06-06
PT82813B (pt) 1988-04-21
ZA864444B (en) 1987-02-25
DK290286A (da) 1986-12-22
DE3684368D1 (de) 1992-04-23
PT82815B (pt) 1988-04-21
NO168428C (no) 1992-02-19
EP0207681A3 (en) 1988-06-01
IL79136A0 (en) 1986-09-30
AU5891986A (en) 1986-12-24

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