PH21886A - Spiro imidazolones for treatments of diabetes complications - Google Patents

Spiro imidazolones for treatments of diabetes complications

Info

Publication number
PH21886A
PH21886A PH32539A PH32539A PH21886A PH 21886 A PH21886 A PH 21886A PH 32539 A PH32539 A PH 32539A PH 32539 A PH32539 A PH 32539A PH 21886 A PH21886 A PH 21886A
Authority
PH
Philippines
Prior art keywords
spiro
pct
imidazolones
treatments
diabetes complications
Prior art date
Application number
PH32539A
Other languages
English (en)
Inventor
Christopher Andrew Lipinski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PH21886A publication Critical patent/PH21886A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PH32539A 1984-07-20 1985-07-18 Spiro imidazolones for treatments of diabetes complications PH21886A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1984/001155 WO1986000807A1 (en) 1984-07-20 1984-07-20 Spiro-imidazolones for treatment of diabetes complications

Publications (1)

Publication Number Publication Date
PH21886A true PH21886A (en) 1988-03-25

Family

ID=22182207

Family Applications (1)

Application Number Title Priority Date Filing Date
PH32539A PH21886A (en) 1984-07-20 1985-07-18 Spiro imidazolones for treatments of diabetes complications

Country Status (19)

Country Link
US (1) US4680306A (fi)
EP (1) EP0171213B1 (fi)
KR (1) KR870000626B1 (fi)
AT (1) ATE37372T1 (fi)
AU (1) AU553719B2 (fi)
CA (1) CA1246085A (fi)
DE (1) DE3565106D1 (fi)
DK (1) DK329485A (fi)
EG (1) EG17281A (fi)
ES (1) ES8604594A1 (fi)
FI (1) FI80037C (fi)
GR (1) GR851763B (fi)
HU (1) HU198212B (fi)
IL (1) IL75801A (fi)
PH (1) PH21886A (fi)
PL (1) PL145598B1 (fi)
PT (1) PT80829B (fi)
WO (1) WO1986000807A1 (fi)
ZA (1) ZA855460B (fi)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3501B1 (ar) * 2014-12-22 2020-07-05 Servier Lab مشتقات 5-{(بيبرازين - 1-يل)-3-أوكسو - بروبيل}- إيميدازوليدين-2، 4 - دايون كمثبطات ل adamts لمعالجة هشاشة العظام)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985888A (en) * 1969-07-24 1976-10-12 Richardson-Merrell Inc. Methods of inducing sedation using certain spiroalkanone-imides
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4127665A (en) * 1978-01-18 1978-11-28 Pfizer Inc. Thienohydantoin derivatives
US4147797A (en) * 1978-08-11 1979-04-03 Pfizer Inc. Spiro-furanohydantoin derivatives
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
IE52879B1 (en) * 1981-05-12 1988-03-30 Ici Plc Pharmaceutical spiro-hydantoin derivatives
ATE11781T1 (de) * 1981-05-13 1985-02-15 Imperial Chemical Industries Plc Pharmazeutische zubereitungen, die spirosuccinimidderivate enthalten.
US4575507A (en) * 1985-05-29 1986-03-11 Pfizer Inc. Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use

Also Published As

Publication number Publication date
ATE37372T1 (de) 1988-10-15
GR851763B (fi) 1985-11-26
ES545353A0 (es) 1986-02-01
FI80037C (fi) 1990-04-10
EP0171213B1 (en) 1988-09-21
ES8604594A1 (es) 1986-02-01
FI861125A (fi) 1986-03-18
KR860001114A (ko) 1986-02-22
DE3565106D1 (en) 1988-10-27
PT80829B (pt) 1987-11-30
US4680306A (en) 1987-07-14
HU198212B (en) 1989-08-28
HUT39087A (en) 1986-08-28
AU4518985A (en) 1986-01-23
KR870000626B1 (ko) 1987-03-26
WO1986000807A1 (en) 1986-02-13
EG17281A (en) 1989-06-30
FI80037B (fi) 1989-12-29
IL75801A (en) 1988-09-30
AU553719B2 (en) 1986-07-24
FI861125A0 (fi) 1986-03-18
DK329485D0 (da) 1985-07-19
DK329485A (da) 1986-01-21
EP0171213A1 (en) 1986-02-12
PL254593A1 (en) 1986-06-17
PL145598B1 (en) 1988-10-31
PT80829A (en) 1985-08-01
ZA855460B (en) 1987-02-25
CA1246085A (en) 1988-12-06
IL75801A0 (en) 1985-11-29

Similar Documents

Publication Publication Date Title
AU1808488A (en) Compounds for the treatment of alzheimer's disease
ES483511A1 (es) Un procedimiento para la preparaion de nuevas espiro-oxazo- lidinohoinas.
HRP920667A2 (en) Application of fultripine active substance for preventing muscle deformation
GR3034508T3 (en) Use of insulin sensitizing agents to treat hypertension.
PL320167A1 (en) 2,2-dichloroalkanocarboxylic acids, method of obtaining them and therapeutic agents containing such compounds and their application in treating insulin immunity
HUT71550A (en) Pharmaceutical agents containing quinuclidine, piperidine or azanorbornane derivatives for treatment of emesis
GR861803B (en) Novel carbonic acid derivatives method for their preparation their use and medicine containing them
GB2188547B (en) Tamoxifen composition for the treatment of psoriasis.
GR852979B (fi)
ZA886097B (en) Pharmaceutical composition for the treatment of psoriasis
RO92632A (ro) Compozitie farmaceutica sinergetica pentru tratamentul inflamatiilor pancreasului
PH21886A (en) Spiro imidazolones for treatments of diabetes complications
IE832854L (en) Spiro-3-hetero-azolones for treatment of diabetic¹complications.
DE3467166D1 (en) Spiro-succinimides for treatment of diabetes complications
ZA871032B (en) Pharmaceutical compositions for the therapy of cerebropatheis on functional and organic base
NO972450L (no) Substituerte 2-(fosfinyloksymetyl)-1,2,5-tiadiazolidin-3-on 1,1-dioksider og preparater og metode for anvendelse derav
IL98200A0 (en) Pharmaceutical composition containing a derivative of substituted-l-valyl-l-prolinamide
ES8609326A1 (es) Un procedimiento para la preparacion de nuevas 1-(aril sustituido)dihidro 1h pirrolizin-3,5-(h,6h)-dionas
SI1304107T1 (en) Use of oxazolidinines derivatives for treating psoriasis