GR851763B - - Google Patents

Info

Publication number
GR851763B
GR851763B GR851763A GR850101763A GR851763B GR 851763 B GR851763 B GR 851763B GR 851763 A GR851763 A GR 851763A GR 850101763 A GR850101763 A GR 850101763A GR 851763 B GR851763 B GR 851763B
Authority
GR
Greece
Prior art keywords
pct
sec
disclosed
date
spiro
Prior art date
Application number
GR851763A
Other languages
English (en)
Inventor
Christopher Andrew Lipinski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GR851763B publication Critical patent/GR851763B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems
GR851763A 1984-07-20 1985-07-16 GR851763B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1984/001155 WO1986000807A1 (en) 1984-07-20 1984-07-20 Spiro-imidazolones for treatment of diabetes complications

Publications (1)

Publication Number Publication Date
GR851763B true GR851763B (el) 1985-11-26

Family

ID=22182207

Family Applications (1)

Application Number Title Priority Date Filing Date
GR851763A GR851763B (el) 1984-07-20 1985-07-16

Country Status (19)

Country Link
US (1) US4680306A (el)
EP (1) EP0171213B1 (el)
KR (1) KR870000626B1 (el)
AT (1) ATE37372T1 (el)
AU (1) AU553719B2 (el)
CA (1) CA1246085A (el)
DE (1) DE3565106D1 (el)
DK (1) DK329485A (el)
EG (1) EG17281A (el)
ES (1) ES8604594A1 (el)
FI (1) FI80037C (el)
GR (1) GR851763B (el)
HU (1) HU198212B (el)
IL (1) IL75801A (el)
PH (1) PH21886A (el)
PL (1) PL145598B1 (el)
PT (1) PT80829B (el)
WO (1) WO1986000807A1 (el)
ZA (1) ZA855460B (el)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3501B1 (ar) * 2014-12-22 2020-07-05 Servier Lab مشتقات 5-{(بيبرازين - 1-يل)-3-أوكسو - بروبيل}- إيميدازوليدين-2، 4 - دايون كمثبطات ل adamts لمعالجة هشاشة العظام)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985888A (en) * 1969-07-24 1976-10-12 Richardson-Merrell Inc. Methods of inducing sedation using certain spiroalkanone-imides
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4127665A (en) * 1978-01-18 1978-11-28 Pfizer Inc. Thienohydantoin derivatives
US4147797A (en) * 1978-08-11 1979-04-03 Pfizer Inc. Spiro-furanohydantoin derivatives
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
IE52879B1 (en) * 1981-05-12 1988-03-30 Ici Plc Pharmaceutical spiro-hydantoin derivatives
EP0065392B1 (en) * 1981-05-13 1985-02-13 Imperial Chemical Industries Plc Pharmaceutical compositions containing spiro succinimide derivatives
US4575507A (en) * 1985-05-29 1986-03-11 Pfizer Inc. Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use

Also Published As

Publication number Publication date
FI861125A (fi) 1986-03-18
PT80829A (en) 1985-08-01
FI861125A0 (fi) 1986-03-18
KR860001114A (ko) 1986-02-22
KR870000626B1 (ko) 1987-03-26
ES545353A0 (es) 1986-02-01
PL254593A1 (en) 1986-06-17
DE3565106D1 (en) 1988-10-27
PL145598B1 (en) 1988-10-31
CA1246085A (en) 1988-12-06
EP0171213A1 (en) 1986-02-12
DK329485A (da) 1986-01-21
FI80037C (fi) 1990-04-10
HUT39087A (en) 1986-08-28
ZA855460B (en) 1987-02-25
ATE37372T1 (de) 1988-10-15
HU198212B (en) 1989-08-28
AU4518985A (en) 1986-01-23
PH21886A (en) 1988-03-25
PT80829B (pt) 1987-11-30
FI80037B (fi) 1989-12-29
AU553719B2 (en) 1986-07-24
IL75801A0 (en) 1985-11-29
EG17281A (en) 1989-06-30
US4680306A (en) 1987-07-14
ES8604594A1 (es) 1986-02-01
EP0171213B1 (en) 1988-09-21
WO1986000807A1 (en) 1986-02-13
DK329485D0 (da) 1985-07-19
IL75801A (en) 1988-09-30

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