FI861125A0 - Vid vaord av diabeteskomplikationer tillaempade spiroimidazoler. - Google Patents

Vid vaord av diabeteskomplikationer tillaempade spiroimidazoler.

Info

Publication number
FI861125A0
FI861125A0 FI861125A FI861125A FI861125A0 FI 861125 A0 FI861125 A0 FI 861125A0 FI 861125 A FI861125 A FI 861125A FI 861125 A FI861125 A FI 861125A FI 861125 A0 FI861125 A0 FI 861125A0
Authority
FI
Finland
Prior art keywords
pct
vaord
tillaempade
spiroimidazoler
diabeteskomplikationer
Prior art date
Application number
FI861125A
Other languages
English (en)
Other versions
FI861125A (fi
FI80037C (fi
FI80037B (fi
Inventor
Christopher Andrew Lipinski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI861125A0 publication Critical patent/FI861125A0/fi
Publication of FI861125A publication Critical patent/FI861125A/fi
Application granted granted Critical
Publication of FI80037B publication Critical patent/FI80037B/fi
Publication of FI80037C publication Critical patent/FI80037C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI861125A 1984-07-20 1986-03-18 Foerfarande av framstaellning av nya terapeutiskt anvaendbara spiro/benso/b/tiofen-7(6h), 4'-imidazolidin/-2',5'-dionderivat. FI80037C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8401155 1984-07-20
PCT/US1984/001155 WO1986000807A1 (en) 1984-07-20 1984-07-20 Spiro-imidazolones for treatment of diabetes complications

Publications (4)

Publication Number Publication Date
FI861125A0 true FI861125A0 (fi) 1986-03-18
FI861125A FI861125A (fi) 1986-03-18
FI80037B FI80037B (fi) 1989-12-29
FI80037C FI80037C (fi) 1990-04-10

Family

ID=22182207

Family Applications (1)

Application Number Title Priority Date Filing Date
FI861125A FI80037C (fi) 1984-07-20 1986-03-18 Foerfarande av framstaellning av nya terapeutiskt anvaendbara spiro/benso/b/tiofen-7(6h), 4'-imidazolidin/-2',5'-dionderivat.

Country Status (19)

Country Link
US (1) US4680306A (fi)
EP (1) EP0171213B1 (fi)
KR (1) KR870000626B1 (fi)
AT (1) ATE37372T1 (fi)
AU (1) AU553719B2 (fi)
CA (1) CA1246085A (fi)
DE (1) DE3565106D1 (fi)
DK (1) DK329485A (fi)
EG (1) EG17281A (fi)
ES (1) ES8604594A1 (fi)
FI (1) FI80037C (fi)
GR (1) GR851763B (fi)
HU (1) HU198212B (fi)
IL (1) IL75801A (fi)
PH (1) PH21886A (fi)
PL (1) PL145598B1 (fi)
PT (1) PT80829B (fi)
WO (1) WO1986000807A1 (fi)
ZA (1) ZA855460B (fi)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3501B1 (ar) * 2014-12-22 2020-07-05 Servier Lab مشتقات 5-{(بيبرازين - 1-يل)-3-أوكسو - بروبيل}- إيميدازوليدين-2، 4 - دايون كمثبطات ل adamts لمعالجة هشاشة العظام)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985888A (en) * 1969-07-24 1976-10-12 Richardson-Merrell Inc. Methods of inducing sedation using certain spiroalkanone-imides
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4127665A (en) * 1978-01-18 1978-11-28 Pfizer Inc. Thienohydantoin derivatives
US4147797A (en) * 1978-08-11 1979-04-03 Pfizer Inc. Spiro-furanohydantoin derivatives
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
IE52879B1 (en) * 1981-05-12 1988-03-30 Ici Plc Pharmaceutical spiro-hydantoin derivatives
EP0065392B1 (en) * 1981-05-13 1985-02-13 Imperial Chemical Industries Plc Pharmaceutical compositions containing spiro succinimide derivatives
US4575507A (en) * 1985-05-29 1986-03-11 Pfizer Inc. Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use

Also Published As

Publication number Publication date
DK329485D0 (da) 1985-07-19
DE3565106D1 (en) 1988-10-27
PT80829B (pt) 1987-11-30
PL145598B1 (en) 1988-10-31
ES545353A0 (es) 1986-02-01
FI861125A (fi) 1986-03-18
KR870000626B1 (ko) 1987-03-26
ATE37372T1 (de) 1988-10-15
EP0171213B1 (en) 1988-09-21
DK329485A (da) 1986-01-21
WO1986000807A1 (en) 1986-02-13
PH21886A (en) 1988-03-25
KR860001114A (ko) 1986-02-22
AU553719B2 (en) 1986-07-24
ES8604594A1 (es) 1986-02-01
EG17281A (en) 1989-06-30
HUT39087A (en) 1986-08-28
HU198212B (en) 1989-08-28
FI80037C (fi) 1990-04-10
IL75801A0 (en) 1985-11-29
IL75801A (en) 1988-09-30
FI80037B (fi) 1989-12-29
EP0171213A1 (en) 1986-02-12
PT80829A (en) 1985-08-01
US4680306A (en) 1987-07-14
GR851763B (fi) 1985-11-26
CA1246085A (en) 1988-12-06
AU4518985A (en) 1986-01-23
PL254593A1 (en) 1986-06-17
ZA855460B (en) 1987-02-25

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: PFIZER INC.