PH20931A - 1,4-dihydropyridines, pharmaceutical compositions containing them and method of use thereof - Google Patents
1,4-dihydropyridines, pharmaceutical compositions containing them and method of use thereofInfo
- Publication number
- PH20931A PH20931A PH32235A PH32235A PH20931A PH 20931 A PH20931 A PH 20931A PH 32235 A PH32235 A PH 32235A PH 32235 A PH32235 A PH 32235A PH 20931 A PH20931 A PH 20931A
- Authority
- PH
- Philippines
- Prior art keywords
- sub
- dihydropyridines
- pharmaceutical compositions
- compositions containing
- sup
- Prior art date
Links
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical class C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004200 2-methoxyethyl group Chemical group [H]C([H])([H])OC([H])([H])C([H])([H])* 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000002253 anti-ischaemic effect Effects 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 229940127292 dihydropyridine calcium channel blocker Drugs 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848412208A GB8412208D0 (en) | 1984-05-12 | 1984-05-12 | Quinolone inotropic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH20931A true PH20931A (en) | 1987-06-05 |
Family
ID=10560892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH32235A PH20931A (en) | 1984-05-12 | 1985-05-07 | 1,4-dihydropyridines, pharmaceutical compositions containing them and method of use thereof |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4654353A (en, 2012) |
| EP (1) | EP0161917B1 (en, 2012) |
| JP (1) | JPS60246368A (en, 2012) |
| KR (1) | KR880000131B1 (en, 2012) |
| AT (1) | ATE50988T1 (en, 2012) |
| AU (1) | AU554257B2 (en, 2012) |
| CA (1) | CA1278573C (en, 2012) |
| DD (1) | DD235867A5 (en, 2012) |
| DE (1) | DE3576499D1 (en, 2012) |
| DK (1) | DK162982C (en, 2012) |
| ES (2) | ES8609252A1 (en, 2012) |
| FI (1) | FI83308C (en, 2012) |
| GB (1) | GB8412208D0 (en, 2012) |
| GR (1) | GR851130B (en, 2012) |
| HU (1) | HU194172B (en, 2012) |
| IE (1) | IE57751B1 (en, 2012) |
| IL (1) | IL75165A (en, 2012) |
| NO (1) | NO851886L (en, 2012) |
| NZ (1) | NZ212033A (en, 2012) |
| PH (1) | PH20931A (en, 2012) |
| PL (1) | PL253328A1 (en, 2012) |
| PT (1) | PT80427B (en, 2012) |
| SU (1) | SU1417795A3 (en, 2012) |
| YU (1) | YU78085A (en, 2012) |
| ZA (1) | ZA853543B (en, 2012) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU199796B (en) * | 1985-08-06 | 1990-03-28 | Boehringer Biochemia Srl | Process for producing 2-thiomethyl-substituted-1,4-dihydropyridines and pharmaceutical compositions comprising such compounds |
| GB8526411D0 (en) * | 1985-10-25 | 1985-11-27 | Pfizer Ltd | Dihydropyridines |
| GB8527698D0 (en) * | 1985-11-09 | 1985-12-11 | Pfizer Ltd | Dihydropyridine antiischaemic & antihypertensive agents |
| IT1213555B (it) * | 1986-12-11 | 1989-12-20 | Boehringer Biochemia Srl | 2 metiltiometildiidropiridine, un processo per laloro preparazione e composizioni farmaceutiche che le contengono. |
| US4920225A (en) * | 1986-12-22 | 1990-04-24 | Laboratoires Syntex S.A. | Resolution of 1,4-dihydropyridine derivatives |
| GB8709447D0 (en) * | 1987-04-21 | 1987-05-28 | Pfizer Ltd | Dihydropyridines |
| FR2687674B1 (fr) * | 1992-02-07 | 1995-05-19 | Roussel Uclaf | Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
| US6541479B1 (en) * | 1997-12-02 | 2003-04-01 | Massachusetts College Of Pharmacy | Calcium channel blockers |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1591089A (en) * | 1976-12-17 | 1981-06-10 | Fujisawa Pharmaceutical Co | 1,4-dihydropyridine derivatives and process for preparation thereof |
| CA1117117A (en) * | 1978-10-10 | 1982-01-26 | Fujisawa Pharmaceutical Co., Ltd. | 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same |
| SE7910521L (sv) * | 1979-12-20 | 1981-06-21 | Haessle Ab | Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma |
| CS228917B2 (en) * | 1981-03-14 | 1984-05-14 | Pfizer | Method of preparing substituted derivatives of 1,4-dihydropyridine |
| NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
| DE3207982A1 (de) * | 1982-03-05 | 1983-09-08 | Bayer Ag, 5090 Leverkusen | Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln |
| DE3363743D1 (en) * | 1982-07-22 | 1986-07-03 | Pfizer Ltd | Dihydropyridine anti-ischaemic and antihypertensive agents |
| DE3311005A1 (de) * | 1983-03-25 | 1984-09-27 | Bayer Ag, 5090 Leverkusen | Chromon- und thiochromonsubstituierte 1,4-dihydropyridinderivate, mehrere verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| EP0164247B1 (en) * | 1984-06-07 | 1989-01-11 | Pfizer Limited | Dihydropyridines |
-
1984
- 1984-05-12 GB GB848412208A patent/GB8412208D0/en active Pending
-
1985
- 1985-04-26 US US06/727,704 patent/US4654353A/en not_active Expired - Lifetime
- 1985-05-07 PH PH32235A patent/PH20931A/en unknown
- 1985-05-09 PT PT80427A patent/PT80427B/pt not_active IP Right Cessation
- 1985-05-09 GR GR851130A patent/GR851130B/el unknown
- 1985-05-09 JP JP60098876A patent/JPS60246368A/ja active Granted
- 1985-05-10 ES ES543033A patent/ES8609252A1/es not_active Expired
- 1985-05-10 YU YU00780/85A patent/YU78085A/xx unknown
- 1985-05-10 DD DD85276212A patent/DD235867A5/de unknown
- 1985-05-10 PL PL25332885A patent/PL253328A1/xx unknown
- 1985-05-10 IL IL75165A patent/IL75165A/xx unknown
- 1985-05-10 HU HU851778A patent/HU194172B/hu unknown
- 1985-05-10 EP EP85303304A patent/EP0161917B1/en not_active Expired - Lifetime
- 1985-05-10 AU AU42269/85A patent/AU554257B2/en not_active Ceased
- 1985-05-10 ZA ZA853543A patent/ZA853543B/xx unknown
- 1985-05-10 NZ NZ212033A patent/NZ212033A/en unknown
- 1985-05-10 DE DE8585303304T patent/DE3576499D1/de not_active Expired - Lifetime
- 1985-05-10 FI FI851857A patent/FI83308C/fi not_active IP Right Cessation
- 1985-05-10 DK DK207885A patent/DK162982C/da active
- 1985-05-10 CA CA000481320A patent/CA1278573C/en not_active Expired - Lifetime
- 1985-05-10 IE IE1168/85A patent/IE57751B1/en not_active IP Right Cessation
- 1985-05-10 NO NO851886A patent/NO851886L/no unknown
- 1985-05-10 AT AT85303304T patent/ATE50988T1/de not_active IP Right Cessation
- 1985-05-11 SU SU853901005A patent/SU1417795A3/ru active
- 1985-05-11 KR KR1019850003214A patent/KR880000131B1/ko not_active Expired
-
1986
- 1986-01-16 ES ES550965A patent/ES8703429A1/es not_active Expired
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH20114A (en) | Dihydropyridines,pharmaceutical compositions containing the same and method of use thereof | |
| ES534505A0 (es) | Un procedimiento para la preparacion de compuestos de 1, 4-dihidropiridina | |
| PH20931A (en) | 1,4-dihydropyridines, pharmaceutical compositions containing them and method of use thereof |