PH19962A - Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as castric anti-secretory agents - Google Patents

Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as castric anti-secretory agents

Info

Publication number
PH19962A
PH19962A PH31520A PH31520A PH19962A PH 19962 A PH19962 A PH 19962A PH 31520 A PH31520 A PH 31520A PH 31520 A PH31520 A PH 31520A PH 19962 A PH19962 A PH 19962A
Authority
PH
Philippines
Prior art keywords
castric
pyridylmethyl
thio
substituted
secretory agents
Prior art date
Application number
PH31520A
Other languages
English (en)
Inventor
John Charles Sih
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of PH19962A publication Critical patent/PH19962A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH31520A 1983-12-05 1984-12-03 Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as castric anti-secretory agents PH19962A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55808783A 1983-12-05 1983-12-05
US06/648,118 US4575554A (en) 1983-12-05 1984-09-06 Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents

Publications (1)

Publication Number Publication Date
PH19962A true PH19962A (en) 1986-08-20

Family

ID=27071629

Family Applications (1)

Application Number Title Priority Date Filing Date
PH31520A PH19962A (en) 1983-12-05 1984-12-03 Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as castric anti-secretory agents

Country Status (16)

Country Link
US (1) US4575554A (en, 2012)
EP (1) EP0150586B1 (en, 2012)
JP (1) JPS60139689A (en, 2012)
KR (1) KR890000382B1 (en, 2012)
AU (1) AU571907B2 (en, 2012)
DE (1) DE3484565D1 (en, 2012)
DK (1) DK577584A (en, 2012)
ES (1) ES8603711A1 (en, 2012)
FI (1) FI83418C (en, 2012)
GR (1) GR81143B (en, 2012)
IE (1) IE58431B1 (en, 2012)
IL (1) IL73433A (en, 2012)
MX (1) MX160796A (en, 2012)
NO (1) NO164473C (en, 2012)
NZ (1) NZ210135A (en, 2012)
PH (1) PH19962A (en, 2012)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2161160B (en) * 1984-07-06 1989-05-24 Fisons Plc Heterocyclic sulphinyl compounds
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
EP0178438A1 (en) * 1984-09-19 1986-04-23 Beecham Group Plc Novel compounds
KR890000387B1 (ko) * 1984-09-24 1989-03-16 디 엎존 캄파니 2-(피리딜알켄술 피닐)벤즈 이미드아졸류의 n-치환 유도체의 제조방법
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
US4743609A (en) * 1985-02-12 1988-05-10 Banyu Pharmaceutical Co., Ltd. Indole derivatives having gastric and antisecretory and cytoprotective properties, and pharmaceutical preparations containing same
EP0234485B1 (de) * 1986-02-20 1992-04-01 Hoechst Aktiengesellschaft Substituierte Thienoimidazol-Derivate, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zubereitungen und ihre Verwendung als Magensäuresekretionshemmer
WO1987005296A1 (en) * 1986-03-07 1987-09-11 Pfizer Inc. 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents
US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
EP0425505B1 (en) * 1988-06-30 1993-03-17 The Upjohn Company Transdermal antisecretory agents for gastrointestinal disease
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
AU5699594A (en) * 1992-12-10 1994-07-04 Byk Gulden Lomberg Chemische Fabrik Gmbh Use of alkylthiopyridines for controlling helicobacter bacteria
CN1045774C (zh) * 1993-06-29 1999-10-20 比克·古尔顿·劳姆贝尔格化学公司 取代的芳硫基烷硫基吡啶、其制法和药用
FI964908A0 (fi) * 1994-06-10 1996-12-09 Byk Gulden Lomberg Chem Fab Helicobacter-bakteerien torjuntaan tarkoitetut tiopyridiinit
WO1997012581A2 (en) * 1995-09-21 1997-04-10 Pharma Pass L.L.C. Novel composition containing an acid-labile omeprazole and process for its preparation
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
WO2002026210A2 (en) * 2000-09-29 2002-04-04 Geneva Pharmaceuticals Inc. Proton pump inhibitor formulation
US20030228363A1 (en) * 2002-06-07 2003-12-11 Patel Mahendra R. Stabilized pharmaceutical compositons containing benzimidazole compounds
US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
JP7029129B2 (ja) * 2016-09-14 2022-03-03 ユーフェン ジェーン ツェン D-アミノ酸オキシダーゼ(daao)阻害剤としての新規な置換ベンゾイミダゾール誘導体
CN112142653B (zh) * 2020-10-22 2022-02-11 成都百泉生物医药科技有限公司 奥美拉唑中间体的制备方法
WO2025085783A1 (en) * 2023-10-20 2025-04-24 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Prazole-based antiviral therapeutics

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
IL66340A (en) * 1981-08-13 1986-08-31 Haessle Ab Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
KR840002371A (ko) * 1981-11-05 1984-06-25 귄터 미카엘, 헤르페르트 수키 치환된 벤즈 이미다졸의 제조방법
DE3216843C2 (de) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds

Also Published As

Publication number Publication date
FI844755L (fi) 1985-06-06
FI83418C (fi) 1991-07-10
IE58431B1 (en) 1993-09-22
US4575554A (en) 1986-03-11
DK577584A (da) 1985-06-06
DE3484565D1 (de) 1991-06-13
AU3564384A (en) 1985-06-13
EP0150586A2 (en) 1985-08-07
DK577584D0 (da) 1984-12-04
JPH0572392B2 (en, 2012) 1993-10-12
IE843095L (en) 1985-06-05
JPS60139689A (ja) 1985-07-24
ES538249A0 (es) 1986-01-16
NO164473B (no) 1990-07-02
KR890000382B1 (ko) 1989-03-15
IL73433A (en) 1988-11-30
MX160796A (es) 1990-05-22
AU571907B2 (en) 1988-04-28
EP0150586B1 (en) 1991-05-08
NZ210135A (en) 1989-01-06
KR850004483A (ko) 1985-07-15
NO164473C (no) 1990-10-10
NO844836L (no) 1985-06-06
IL73433A0 (en) 1985-02-28
FI83418B (fi) 1991-03-28
EP0150586A3 (en) 1985-08-28
ES8603711A1 (es) 1986-01-16
FI844755A0 (fi) 1984-12-03
GR81143B (en) 1985-04-04

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