PH12015502118B1 - Pyridin-4-yl derivatives - Google Patents
Pyridin-4-yl derivatives Download PDFInfo
- Publication number
- PH12015502118B1 PH12015502118B1 PH12015502118A PH12015502118A PH12015502118B1 PH 12015502118 B1 PH12015502118 B1 PH 12015502118B1 PH 12015502118 A PH12015502118 A PH 12015502118A PH 12015502118 A PH12015502118 A PH 12015502118A PH 12015502118 B1 PH12015502118 B1 PH 12015502118B1
- Authority
- PH
- Philippines
- Prior art keywords
- ethyl
- hydroxyacetamide
- oxadiazol
- compound according
- hydroxypropyl
- Prior art date
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- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 title 1
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- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13159482 | 2013-03-15 | ||
| PCT/IB2014/059794 WO2014141171A1 (en) | 2013-03-15 | 2014-03-14 | Pyridin-4-yl derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PH12015502118A1 PH12015502118A1 (en) | 2016-01-25 |
| PH12015502118B1 true PH12015502118B1 (en) | 2016-01-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| PH12015502118A PH12015502118B1 (en) | 2013-03-15 | 2015-09-14 | Pyridin-4-yl derivatives |
Country Status (33)
| Country | Link |
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| US (1) | US9617250B2 (https=) |
| EP (1) | EP2970236B1 (https=) |
| JP (1) | JP6387361B2 (https=) |
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| CN (1) | CN105189487B (https=) |
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| BR (1) | BR112015023161B1 (https=) |
| CA (1) | CA2900910C (https=) |
| CL (1) | CL2015002620A1 (https=) |
| CY (1) | CY1119619T1 (https=) |
| DK (1) | DK2970236T3 (https=) |
| EA (1) | EA029309B1 (https=) |
| ES (1) | ES2649475T3 (https=) |
| HR (1) | HRP20171763T1 (https=) |
| HU (1) | HUE035154T2 (https=) |
| IL (1) | IL241363B (https=) |
| LT (1) | LT2970236T (https=) |
| MA (1) | MA38482B1 (https=) |
| MX (1) | MX363545B (https=) |
| MY (1) | MY173573A (https=) |
| NO (1) | NO2970236T3 (https=) |
| NZ (1) | NZ713080A (https=) |
| PH (1) | PH12015502118B1 (https=) |
| PL (1) | PL2970236T3 (https=) |
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| SI (1) | SI2970236T1 (https=) |
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| UA (1) | UA115357C2 (https=) |
| WO (1) | WO2014141171A1 (https=) |
| ZA (1) | ZA201507657B (https=) |
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| ES2649156T3 (es) | 2013-01-14 | 2018-01-10 | Incyte Holdings Corporation | Compuestos bicíclicos de carboxamida aromática útiles como inhibidores de quinasas Pim |
| PE20191245A1 (es) | 2013-01-15 | 2019-09-18 | Incyte Holdings Corp | Compuestos de tiazolcarboxamidas y piridinacarboxamida utiles como inhibidores de quinasa pim |
| EA201690458A1 (ru) | 2013-08-23 | 2016-07-29 | Инсайт Корпорейшн | Фуро- и тиенопиридинкарбоксамиды, используемые в качестве ингибиторов pim-киназы |
| US9822124B2 (en) | 2014-07-14 | 2017-11-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as Pim kinase inhibitors |
| US9580418B2 (en) | 2014-07-14 | 2017-02-28 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors |
| PH12017502097B1 (en) | 2015-05-20 | 2023-05-05 | Idorsia Pharmaceuticals Ltd | Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol |
| WO2016196244A1 (en) | 2015-05-29 | 2016-12-08 | Incyte Corporation | Pyridineamine compounds useful as pim kinase inhibitors |
| WO2017004610A1 (en) * | 2015-07-02 | 2017-01-05 | Exelixis, Inc. | Tercyclic s1p3-sparing, s1p1 receptor agonists |
| TWI734699B (zh) | 2015-09-09 | 2021-08-01 | 美商英塞特公司 | Ｐｉｍ激酶抑制劑之鹽 |
| US9920032B2 (en) | 2015-10-02 | 2018-03-20 | Incyte Corporation | Heterocyclic compounds useful as pim kinase inhibitors |
| WO2019113487A1 (en) | 2017-12-08 | 2019-06-13 | Incyte Corporation | Low dose combination therapy for treatment of myeloproliferative neoplasms |
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| AU7686891A (en) | 1990-04-05 | 1991-10-30 | American National Red Cross, The | A protein family related to immediate-early protein expressed by human endothelial cells during differentiation |
| US6423508B1 (en) | 1998-03-09 | 2002-07-23 | Smithkline Beecham Corporation | Polynucleotide sequences of human EDG-1c |
| WO2004035538A1 (en) | 2002-10-15 | 2004-04-29 | Merck & Co., Inc. | Process for making azetidine-3-carboxylic acid |
| PT2069336E (pt) * | 2006-09-07 | 2013-03-07 | Actelion Pharmaceuticals Ltd | Derivados de piridin-4-ilo como agentes imunomoduladores |
| PL2069335T3 (pl) | 2006-09-08 | 2013-05-31 | Actelion Pharmaceuticals Ltd | Pochodne pirydyn-3-ylu jako środki immunomodulujące |
| ES2393412T3 (es) | 2006-09-21 | 2012-12-21 | Actelion Pharmaceuticals Ltd. | Derivados de fenilo y su uso como inmunomoduladores |
| BRPI0808789A2 (pt) | 2007-03-16 | 2014-08-12 | Actelion Pharmaceuticals Ltd | Compostos e composição farmacêutica de derivados aminopiridina e uso destes |
| PT2195311E (pt) | 2007-08-17 | 2011-05-25 | Actelion Pharmaceuticals Ltd | Derivados de piridina como moduladores do receptor s1p1/edg1 |
| MX2010003612A (es) | 2007-10-04 | 2010-04-30 | Merck Serono Sa | Derivados de oxadiazol. |
| KR20100092473A (ko) | 2007-11-01 | 2010-08-20 | 액테리온 파마슈티칼 리미티드 | 신규한 피리미딘 유도체 |
| WO2009109907A1 (en) | 2008-03-06 | 2009-09-11 | Actelion Pharmaceuticals Ltd | Novel pyrimidine-pyridine derivatives |
| EP2262799B1 (en) | 2008-03-06 | 2012-07-04 | Actelion Pharmaceuticals Ltd. | Pyridine compounds |
| CA2715317A1 (en) | 2008-03-07 | 2009-09-11 | Actelion Pharmaceuticals Ltd | Novel aminomethyl benzene derivatives |
| WO2009109872A1 (en) * | 2008-03-07 | 2009-09-11 | Actelion Pharmaceuticals Ltd | Pyridin-2-yl derivatives as immunomodulating agents |
| EP3782991A1 (en) * | 2008-05-14 | 2021-02-24 | The Scripps Research Institute | Novel modulators of sphingosine phosphate receptors |
| ES2517265T3 (es) | 2009-03-03 | 2014-11-03 | Merck Serono S.A. | Derivados de oxadiazol piridina |
| CA2767585C (en) | 2009-07-16 | 2017-09-26 | Actelion Pharmaceuticals Ltd | Pyridin-4-yl derivatives |
| TW201120016A (en) | 2009-12-08 | 2011-06-16 | Abbott Lab | Novel oxadiazole compounds |
| MA34910B1 (fr) | 2011-01-19 | 2014-02-01 | Actelion Pharmaceuticals Ltd | Dérivés de 2-methoxy-pyridin-4-yl |
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