PH12015502118B1 - Pyridin-4-yl derivatives - Google Patents
Pyridin-4-yl derivatives Download PDFInfo
- Publication number
- PH12015502118B1 PH12015502118B1 PH12015502118A PH12015502118A PH12015502118B1 PH 12015502118 B1 PH12015502118 B1 PH 12015502118B1 PH 12015502118 A PH12015502118 A PH 12015502118A PH 12015502118 A PH12015502118 A PH 12015502118A PH 12015502118 B1 PH12015502118 B1 PH 12015502118B1
- Authority
- PH
- Philippines
- Prior art keywords
- ethyl
- hydroxyacetamide
- oxadiazol
- compound according
- hydroxypropyl
- Prior art date
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- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 title 1
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Classifications
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- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P5/00—Drugs for disorders of the endocrine system
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
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- Pulmonology (AREA)
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- Neurology (AREA)
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- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13159482 | 2013-03-15 | ||
| PCT/IB2014/059794 WO2014141171A1 (en) | 2013-03-15 | 2014-03-14 | Pyridin-4-yl derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PH12015502118A1 PH12015502118A1 (en) | 2016-01-25 |
| PH12015502118B1 true PH12015502118B1 (en) | 2016-01-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH12015502118A PH12015502118B1 (en) | 2013-03-15 | 2015-09-14 | Pyridin-4-yl derivatives |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US9617250B2 (OSRAM) |
| EP (1) | EP2970236B1 (OSRAM) |
| JP (1) | JP6387361B2 (OSRAM) |
| KR (1) | KR102212975B1 (OSRAM) |
| CN (1) | CN105189487B (OSRAM) |
| AR (1) | AR095523A1 (OSRAM) |
| AU (1) | AU2014229217B2 (OSRAM) |
| BR (1) | BR112015023161B1 (OSRAM) |
| CA (1) | CA2900910C (OSRAM) |
| CL (1) | CL2015002620A1 (OSRAM) |
| CY (1) | CY1119619T1 (OSRAM) |
| DK (1) | DK2970236T3 (OSRAM) |
| EA (1) | EA029309B1 (OSRAM) |
| ES (1) | ES2649475T3 (OSRAM) |
| HR (1) | HRP20171763T1 (OSRAM) |
| HU (1) | HUE035154T2 (OSRAM) |
| IL (1) | IL241363B (OSRAM) |
| LT (1) | LT2970236T (OSRAM) |
| MA (1) | MA38482B1 (OSRAM) |
| MX (1) | MX363545B (OSRAM) |
| MY (1) | MY173573A (OSRAM) |
| NO (1) | NO2970236T3 (OSRAM) |
| NZ (1) | NZ713080A (OSRAM) |
| PH (1) | PH12015502118B1 (OSRAM) |
| PL (1) | PL2970236T3 (OSRAM) |
| PT (1) | PT2970236T (OSRAM) |
| SA (1) | SA515361104B1 (OSRAM) |
| SG (1) | SG11201507227UA (OSRAM) |
| SI (1) | SI2970236T1 (OSRAM) |
| TW (1) | TWI623534B (OSRAM) |
| UA (1) | UA115357C2 (OSRAM) |
| WO (1) | WO2014141171A1 (OSRAM) |
| ZA (1) | ZA201507657B (OSRAM) |
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| WO2014110574A1 (en) | 2013-01-14 | 2014-07-17 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors |
| RS60244B1 (sr) | 2013-01-15 | 2020-06-30 | Incyte Holdings Corp | Jedinjenja tiazolkarboksamida i piridinkarboksamida korisna kao inhibitori pim kinaze |
| WO2015027124A1 (en) | 2013-08-23 | 2015-02-26 | Incyte Corporation | Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors |
| WO2016010897A1 (en) | 2014-07-14 | 2016-01-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors |
| US9580418B2 (en) | 2014-07-14 | 2017-02-28 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors |
| US10385043B2 (en) | 2015-05-20 | 2019-08-20 | Idorsia Pharmaceuticals Ltd | Crystalline form of the compound (S)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol |
| US9540347B2 (en) | 2015-05-29 | 2017-01-10 | Incyte Corporation | Pyridineamine compounds useful as Pim kinase inhibitors |
| WO2017004610A1 (en) * | 2015-07-02 | 2017-01-05 | Exelixis, Inc. | Tercyclic s1p3-sparing, s1p1 receptor agonists |
| AR105967A1 (es) | 2015-09-09 | 2017-11-29 | Incyte Corp | Sales de un inhibidor de pim quinasa |
| US9920032B2 (en) | 2015-10-02 | 2018-03-20 | Incyte Corporation | Heterocyclic compounds useful as pim kinase inhibitors |
| AR113922A1 (es) | 2017-12-08 | 2020-07-01 | Incyte Corp | Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas |
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| AU7686891A (en) | 1990-04-05 | 1991-10-30 | American National Red Cross, The | A protein family related to immediate-early protein expressed by human endothelial cells during differentiation |
| EP1070080A4 (en) | 1998-03-09 | 2004-12-29 | Smithkline Beecham Corp | HUMAN EDG-1c POLYNUCLEOTIDES AND POLYPEPTIDES AND THEIR APPLICATIONS |
| WO2004035538A1 (en) | 2002-10-15 | 2004-04-29 | Merck & Co., Inc. | Process for making azetidine-3-carboxylic acid |
| KR101470659B1 (ko) * | 2006-09-07 | 2014-12-08 | 액테리온 파마슈티칼 리미티드 | 면역조절제로서 피리딘-4-일 유도체 |
| US8288554B2 (en) | 2006-09-08 | 2012-10-16 | Actelion Pharmaceuticals Ltd. | Pyridin-3-yl derivatives as immunomodulating agents |
| EP2069318B1 (en) | 2006-09-21 | 2012-09-12 | Actelion Pharmaceuticals Ltd. | Phenyl derivatives and their use as immunomodulators |
| MX2009009597A (es) | 2007-03-16 | 2009-09-16 | Actelion Pharmaceuticals Ltd | Derivados de amino-piridina como agonistas del receptor s1p1/edg1. |
| CN102648198B (zh) | 2007-08-17 | 2015-04-01 | 埃科特莱茵药品有限公司 | 作为s1p1/edg1受体调节剂的吡啶衍生物 |
| CA2696863C (en) | 2007-10-04 | 2016-10-18 | Anna Quattropani | Oxadiazole derivatives |
| BRPI0818804A2 (pt) | 2007-11-01 | 2015-04-22 | Actelion Pharmaceuticals Ltd | Composto derivado de pirimidina, composição farmacêutica que o compreende e uso desse composto. |
| US20110028448A1 (en) | 2008-03-06 | 2011-02-03 | Martin Bolli | Pyridine compounds |
| EP2262800A1 (en) | 2008-03-06 | 2010-12-22 | Actelion Pharmaceuticals Ltd. | Novel pyrimidine-pyridine derivatives |
| SI2252609T1 (sl) | 2008-03-07 | 2013-07-31 | Actelion Pharmaceuticals Ltd. | Derivati piridin-2-ila kot imunomodulacijska sredstva |
| EP2262782B1 (en) | 2008-03-07 | 2012-07-04 | Actelion Pharmaceuticals Ltd. | Novel aminomethyl benzene derivatives |
| EP2913326B1 (en) * | 2008-05-14 | 2020-07-15 | The Scripps Research Institute | Novel modulators of sphingosine phosphate receptors |
| WO2010100142A1 (en) | 2009-03-03 | 2010-09-10 | Merck Serono S.A. | Oxazole pyridine derivatives useful as s1p1 receptor agonists |
| AR077413A1 (es) | 2009-07-16 | 2011-08-24 | Actelion Pharmaceuticals Ltd | Derivados piridin-4-ilo |
| TW201120016A (en) | 2009-12-08 | 2011-06-16 | Abbott Lab | Novel oxadiazole compounds |
| ES2544086T3 (es) | 2011-01-19 | 2015-08-27 | Actelion Pharmaceuticals Ltd. | Derivados de 2-metoxi-piridin-4-ilo |
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2015
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2017
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