PH12015502042A1 - Use of linagliptin in cardio-and renoprotective antidiabetic therapy - Google Patents

Use of linagliptin in cardio-and renoprotective antidiabetic therapy

Info

Publication number
PH12015502042A1
PH12015502042A1 PH12015502042A PH12015502042A PH12015502042A1 PH 12015502042 A1 PH12015502042 A1 PH 12015502042A1 PH 12015502042 A PH12015502042 A PH 12015502042A PH 12015502042 A PH12015502042 A PH 12015502042A PH 12015502042 A1 PH12015502042 A1 PH 12015502042A1
Authority
PH
Philippines
Prior art keywords
cardio
renoprotective
linagliptin
antidiabetic therapy
therapy
Prior art date
Application number
PH12015502042A
Other languages
English (en)
Other versions
PH12015502042B1 (en
Inventor
Johansen Odd-Erik
Von Eynatten Maximilian
Klein Thomas
Woerle Hans-Juergen
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50277246&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH12015502042(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of PH12015502042B1 publication Critical patent/PH12015502042B1/en
Publication of PH12015502042A1 publication Critical patent/PH12015502042A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH12015502042A 2013-03-15 2015-09-10 Use of linagliptin in cardio-and renoprotective antidiabetic therapy PH12015502042A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13159624 2013-03-15
EP13177311 2013-07-19
PCT/EP2014/055113 WO2014140284A1 (en) 2013-03-15 2014-03-14 Use of linagliptin in cardio- and renoprotective antidiabetic therapy

Publications (2)

Publication Number Publication Date
PH12015502042B1 PH12015502042B1 (en) 2016-01-18
PH12015502042A1 true PH12015502042A1 (en) 2016-01-18

Family

ID=50277246

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12015502042A PH12015502042A1 (en) 2013-03-15 2015-09-10 Use of linagliptin in cardio-and renoprotective antidiabetic therapy

Country Status (14)

Country Link
US (9) US20140274889A1 (https=)
EP (4) EP2968344A1 (https=)
JP (4) JP2016510795A (https=)
KR (2) KR20150128726A (https=)
CN (2) CN110075098A (https=)
AU (2) AU2014230096C1 (https=)
BR (1) BR112015020209A2 (https=)
CA (1) CA2903577C (https=)
CL (1) CL2015002369A1 (https=)
EA (1) EA037712B1 (https=)
IL (1) IL240064A0 (https=)
MX (2) MX2015011466A (https=)
PH (1) PH12015502042A1 (https=)
WO (1) WO2014140284A1 (https=)

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US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
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CA3070513C (en) 2010-05-05 2023-01-03 Boehringer Ingelheim International Gmbh A dpp-4 inhibitor for use in treatment of skin-alterations or necrosis
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US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
WO2013171167A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
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US9968659B2 (en) 2016-03-04 2018-05-15 Novo Nordisk A/S Liraglutide in cardiovascular conditions
JPWO2017170434A1 (ja) * 2016-03-28 2019-01-31 インターセプト ファーマシューティカルズ, インコーポレイテッド Fxrアゴニストとarbの組み合わせ医薬
JP7221694B2 (ja) 2016-04-28 2023-02-14 ノヴォ ノルディスク アー/エス 心血管状態におけるセマグルチド
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WO2020016230A1 (en) * 2018-07-17 2020-01-23 Boehringer Ingelheim International Gmbh Cardio- and renosafe antidiabetic therapy
WO2020016232A1 (en) * 2018-07-17 2020-01-23 Boehringer Ingelheim International Gmbh Cardiosafe antidiabetic therapy
JP7227380B2 (ja) * 2018-12-18 2023-02-21 武漢人福創新薬物研発中心有限公司 フェニルピロリジン化合物及びその用途
WO2022244846A1 (ja) * 2021-05-19 2022-11-24 Kagami株式会社 細胞増殖の調整のための組成物及び細胞増殖の調整方法

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PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
JP2010500326A (ja) 2006-08-08 2010-01-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 糖尿病の治療のためのdpp−iv阻害剤としてのピロロ[3,2−d]ピリミジン
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
UY32177A (es) * 2008-10-16 2010-05-31 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con control glucémico insuficiente a pesar de la terapia con fármaco, oral o no, antidiabético
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JP5662453B2 (ja) * 2009-10-02 2015-01-28 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 医薬組成物の治療上の使用
KR20240090632A (ko) * 2009-11-27 2024-06-21 베링거 인겔하임 인터내셔날 게엠베하 리나글립틴과 같은 dpp-iv 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료
AR083878A1 (es) * 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
WO2013171167A1 (en) * 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
JP6374862B2 (ja) * 2012-05-24 2018-08-15 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 自己免疫性糖尿病、特に、ladaの治療に使用するためのdpp−4阻害剤としてのキサンチン誘導体

Also Published As

Publication number Publication date
CA2903577A1 (en) 2014-09-18
EP3409279A1 (en) 2018-12-05
US20180263990A1 (en) 2018-09-20
JP2021095409A (ja) 2021-06-24
US20250025470A1 (en) 2025-01-23
AU2014230096B2 (en) 2019-02-21
EA037712B1 (ru) 2021-05-13
EP4364796A3 (en) 2024-07-24
US20160089373A1 (en) 2016-03-31
KR20210099201A (ko) 2021-08-11
NZ710249A (en) 2021-04-30
EP3744327A1 (en) 2020-12-02
CA2903577C (en) 2023-10-17
US20140274889A1 (en) 2014-09-18
EP4364796A2 (en) 2024-05-08
KR20150128726A (ko) 2015-11-18
WO2014140284A1 (en) 2014-09-18
JP2019112409A (ja) 2019-07-11
IL240064A0 (en) 2015-09-24
BR112015020209A2 (pt) 2017-07-18
CN110075098A (zh) 2019-08-02
AU2019203445A1 (en) 2019-06-06
CL2015002369A1 (es) 2016-02-19
US20240033270A1 (en) 2024-02-01
US20210205316A1 (en) 2021-07-08
AU2014230096C1 (en) 2019-08-29
JP2016510795A (ja) 2016-04-11
MX2015011466A (es) 2016-01-22
EP2968344A1 (en) 2016-01-20
US20190192523A1 (en) 2019-06-27
US20170065596A1 (en) 2017-03-09
CN105188706A (zh) 2015-12-23
US20200338086A1 (en) 2020-10-29
PH12015502042B1 (en) 2016-01-18
JP2025115998A (ja) 2025-08-07
EA201500934A1 (ru) 2016-03-31
MX2021014242A (es) 2022-01-06
AU2014230096A1 (en) 2015-08-06

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