PH12014502834B1 - Pharmaceutical form for extended release of active substances - Google Patents

Pharmaceutical form for extended release of active substances

Info

Publication number
PH12014502834B1
PH12014502834B1 PH12014502834A PH12014502834A PH12014502834B1 PH 12014502834 B1 PH12014502834 B1 PH 12014502834B1 PH 12014502834 A PH12014502834 A PH 12014502834A PH 12014502834 A PH12014502834 A PH 12014502834A PH 12014502834 B1 PH12014502834 B1 PH 12014502834B1
Authority
PH
Philippines
Prior art keywords
pharmaceutical form
active substances
extended release
active substance
release
Prior art date
Application number
PH12014502834A
Other languages
English (en)
Other versions
PH12014502834A1 (en
Inventor
Gernot Francas
Karl-Heinz Przyklenk
Original Assignee
Hennig Arzneimittel Gmbh And Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hennig Arzneimittel Gmbh And Co Kg filed Critical Hennig Arzneimittel Gmbh And Co Kg
Publication of PH12014502834A1 publication Critical patent/PH12014502834A1/en
Publication of PH12014502834B1 publication Critical patent/PH12014502834B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH12014502834A 2012-06-25 2014-12-19 Pharmaceutical form for extended release of active substances PH12014502834B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102012105512.2A DE102012105512A1 (de) 2012-06-25 2012-06-25 Arzneiform zur verlängerten Freisetzung von Wirkstoffen
PCT/EP2013/063163 WO2014001268A1 (de) 2012-06-25 2013-06-24 Arzneiform zur verlängerten freisetzung von wirkstoffen

Publications (2)

Publication Number Publication Date
PH12014502834A1 PH12014502834A1 (en) 2015-02-02
PH12014502834B1 true PH12014502834B1 (en) 2019-12-04

Family

ID=48670585

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12014502834A PH12014502834B1 (en) 2012-06-25 2014-12-19 Pharmaceutical form for extended release of active substances

Country Status (22)

Country Link
EP (1) EP2863891B1 (enExample)
KR (1) KR102160837B1 (enExample)
AU (1) AU2013283474B2 (enExample)
BR (1) BR112014032583B1 (enExample)
CA (1) CA2876294C (enExample)
CO (1) CO7240370A2 (enExample)
DE (1) DE102012105512A1 (enExample)
EA (2) EA028064B1 (enExample)
ES (1) ES2817248T3 (enExample)
HR (1) HRP20201534T1 (enExample)
HU (1) HUE050945T2 (enExample)
IL (1) IL236465B (enExample)
IN (1) IN2014MN02511A (enExample)
LT (1) LT2863891T (enExample)
MX (1) MX371143B (enExample)
PH (1) PH12014502834B1 (enExample)
PL (1) PL2863891T3 (enExample)
PT (1) PT2863891T (enExample)
RS (1) RS60872B1 (enExample)
SI (1) SI2863891T1 (enExample)
UA (1) UA116776C2 (enExample)
WO (1) WO2014001268A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3042642A1 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
ES2720731T3 (es) * 2014-06-26 2019-07-24 Hennig Arzneimittel Gmbh&Co Kg Medicamento para el tratamiento del vértigo de diferentes orígenes
DK3169315T3 (da) 2014-07-17 2020-08-10 Pharmaceutical Manufacturing Res Services In Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse
AU2015336065A1 (en) 2014-10-20 2017-05-04 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
KR101625344B1 (ko) * 2015-12-21 2016-06-08 주식회사 유영제약 세레콕시브 및 둘록세틴을 함유하는 약제학적 조성물

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
IE80467B1 (en) * 1995-07-03 1998-07-29 Elan Corp Plc Controlled release formulations for poorly soluble drugs
DK0996429T3 (da) * 1997-10-27 2003-05-26 Merck Patent Gmbh Faste opløsninger og faste dispersioner i vand tungtopløselige lægemidler
US6368622B2 (en) * 1999-01-29 2002-04-09 Abbott Laboratories Process for preparing solid formulations of lipid regulating agents with enhanced dissolution and absorption
US7374779B2 (en) * 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
US20070148232A1 (en) * 2003-12-31 2007-06-28 Pfizer Inc. Stabilized pharmaceutical solid compositions of low-solubility drugs and poloxamers, and stabilizing polymers
US20050281876A1 (en) * 2004-06-18 2005-12-22 Shun-Por Li Solid dosage form for acid-labile active ingredient
DE102005014141B4 (de) * 2005-03-23 2006-12-21 Hennig Arzneimittel Gmbh & Co. Kg Tablettenförmige Retardzubereitung gegen Schwindel
EP1942888A2 (en) 2005-11-02 2008-07-16 Cytokinetics, Inc. Certain chemical entities, compositions, and methods
WO2007086078A2 (en) * 2006-01-30 2007-08-02 Panacea Biotec Ltd. Novel pharmaceutical compositions and process of preparation thereof
CN101049309A (zh) * 2006-04-03 2007-10-10 陈茜 桂利嗪滴丸及其制备方法
HRP20191104T1 (hr) * 2007-09-25 2019-09-20 Solubest Ltd. Pripravci koji sadrže lipofilne aktivne spojeve i postupak za njihovu pripremu
BRPI0820770A2 (pt) * 2007-12-12 2015-06-16 Basf Se Sal solúvel em água polimérico de medicamentos, forma de administração sólida, e, método para produzir sais solúveis em água poliméricos de medicamentos.
AU2010257752B2 (en) * 2009-06-11 2015-04-09 Photocure Asa Solid compositions comprising 5-aminolevulinic acid
WO2011024029A1 (en) * 2009-08-24 2011-03-03 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Fast disintegrating dosage forms of cinnarizine and dimenhydrinate combination
DE102011051304A1 (de) * 2011-06-24 2012-12-27 Hennig Arzneimittel Gmbh & Co. Kg Wirkstoffmatrix
DE102011051308A1 (de) * 2011-06-24 2012-12-27 Hennig Arzneimittel Gmbh & Co. Kg Herstellungsverfahren und Arzneiform
DE102011053068A1 (de) * 2011-08-29 2013-02-28 Hennig Arzneimittel Gmbh & Co. Kg Darreichungsform mit stabilisierten Wirkstoffpartikeln

Also Published As

Publication number Publication date
BR112014032583B1 (pt) 2022-05-17
PL2863891T3 (pl) 2021-01-25
EP2863891B1 (de) 2020-08-26
IL236465B (en) 2020-06-30
HRP20201534T1 (hr) 2021-02-19
WO2014001268A1 (de) 2014-01-03
EA201500043A1 (ru) 2015-09-30
MX371143B (es) 2020-01-20
EA035815B1 (ru) 2020-08-14
KR102160837B1 (ko) 2020-09-29
CA2876294A1 (en) 2014-01-03
SI2863891T1 (sl) 2020-11-30
DE102012105512A1 (de) 2014-04-24
IL236465A0 (en) 2015-02-26
BR112014032583A2 (pt) 2017-06-27
LT2863891T (lt) 2020-12-10
PT2863891T (pt) 2020-09-25
EA201792143A1 (ru) 2018-05-31
HUE050945T2 (hu) 2021-01-28
PH12014502834A1 (en) 2015-02-02
AU2013283474A1 (en) 2015-01-29
UA116776C2 (uk) 2018-05-10
CO7240370A2 (es) 2015-04-17
ES2817248T3 (es) 2021-04-06
EP2863891A1 (de) 2015-04-29
BR112014032583A8 (pt) 2021-06-22
CA2876294C (en) 2020-09-08
IN2014MN02511A (enExample) 2015-07-17
EA028064B1 (ru) 2017-10-31
AU2013283474B2 (en) 2017-12-14
RS60872B1 (sr) 2020-11-30
KR20150041612A (ko) 2015-04-16
MX2014015642A (es) 2015-08-05

Similar Documents

Publication Publication Date Title
PH12014502834A1 (en) Pharmaceutical form for extended release of active substances
EP2981612A4 (en) Compositions and methods for in vivo excision of hiv-1 proviral dna
CL2015001020A1 (es) Compuestos derivados de 4-carboxamido-isoindolinona, inhibidores selectivos de parp-1; proceso de preparacion; composicion farmaceutica; un metodo in vitro; un producto; y su uso como medicamento con actividad antineoplasica
EP3222278A4 (en) Use of azelnidipine in preparing medicinal composition for treating cancers
AR093377A1 (es) Anticuerpos anti-notch y conjugados de anticuerpo-farmaco
EP3206706A4 (en) Stable injectable composition of pharmaceutically active agents and process for its preparation
PH12015501998B1 (en) Heterocyclic compounds and their uses
MY169159A (en) Piperidino-pyrimidine derivatives for the treatment of viral infections
CL2012003075A1 (es) Composicion farmaceutica en solucion de pazopanib, estable y para uso oftalmico; metodo para la preparacion de dicha solucion.
EP3072536A4 (en) Hydrophilic electrospinning biological composite stent material used for tissue regeneration and preparation method and application thereof
PH12015502535A1 (en) Process for the preparation of erythrocytes loaded with one or more substances of pharmaceutical interest and so obtained erythrocytes
EP3235512A4 (en) Method using polyethylene glycol to prepare fibroin nano/microspheres, and application of method in controlled drug release
EP3070163A4 (en) Method for preparing induced pluripotent stem cell, composition used in method, and uses thereof
MY191875A (en) Solid dosage form
MX2015012416A (es) Compuestos heterociclicos y sus usos.
PT2736488E (pt) Composições farmacêuticas contendo rifaximina, processos para a sua preparação e sua utilização no tratamento de infeções vaginais
PH12015502556A1 (en) Modified release formulation
MX2014012164A (es) Composiciones a base de probioticos y un complejo de polen de abejas/arcilla, su preparacion y sus usos en nutricion y en terapeutica.
GB2497453A (en) Pharmaceutical composition and methods of treating and preventing the diseases caused by HIV or associated with HIV
EP2552426A4 (en) DEVICE FOR DELIVERY OF INTRAVAGINAL DRUGS
IL246525B (en) Pomegranate derived cell culture and methods for preparing and using the same
EP3037099A4 (en) Pharmaceutical composition, preparation method therefor and use thereof
MX361407B (es) Formulaciones de liberacion controlada de hidrocortisona.
EP2875814A4 (en) LIQUID COMPOSITION CONTAINING TAXANE ACTIVE INGREDIENT, MANUFACTURING METHOD THEREOF, AND LIQUID MEDICINAL PREPARATION
WO2013190509A3 (en) Preparation of intermediates of boceprevir