PH12012500992A1 - Compound, certain novel forms thereof, pharmaceutical compositions thereof and methods for preparation and use - Google Patents

Compound, certain novel forms thereof, pharmaceutical compositions thereof and methods for preparation and use

Info

Publication number
PH12012500992A1
PH12012500992A1 PH1/2012/500992A PH12012500992A PH12012500992A1 PH 12012500992 A1 PH12012500992 A1 PH 12012500992A1 PH 12012500992 A PH12012500992 A PH 12012500992A PH 12012500992 A1 PH12012500992 A1 PH 12012500992A1
Authority
PH
Philippines
Prior art keywords
compound
methods
preparation
pharmaceutical compositions
certain novel
Prior art date
Application number
PH1/2012/500992A
Other languages
English (en)
Inventor
Hong Jia
Wenji Li
Yang Sai
Wei-Guo Su
Zhenping Tian
Yumin Cui
Weihan Zhang
Yongxin Ren
Jiangyong Shao
Zhenping Wu
Original Assignee
Hutchison Medipharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44029398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH12012500992(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hutchison Medipharma Ltd filed Critical Hutchison Medipharma Ltd
Publication of PH12012500992A1 publication Critical patent/PH12012500992A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
PH1/2012/500992A 2009-11-23 2010-11-23 Compound, certain novel forms thereof, pharmaceutical compositions thereof and methods for preparation and use PH12012500992A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2009101992592A CN102070618B (zh) 2009-11-23 2009-11-23 一种化合物及其晶体
PCT/CN2010/078997 WO2011060746A1 (en) 2009-11-23 2010-11-23 Compound, certain novel forms thereof, pharmaceutical compositions thereof and methods for preparation and use

Publications (1)

Publication Number Publication Date
PH12012500992A1 true PH12012500992A1 (en) 2016-09-09

Family

ID=44029398

Family Applications (1)

Application Number Title Priority Date Filing Date
PH1/2012/500992A PH12012500992A1 (en) 2009-11-23 2010-11-23 Compound, certain novel forms thereof, pharmaceutical compositions thereof and methods for preparation and use

Country Status (19)

Country Link
US (2) US8658658B2 (en:Method)
EP (1) EP2504331B1 (en:Method)
JP (1) JP5758399B2 (en:Method)
KR (1) KR101513784B1 (en:Method)
CN (2) CN102070618B (en:Method)
AU (1) AU2010321366B2 (en:Method)
BR (1) BR112012012138B1 (en:Method)
CA (1) CA2781066C (en:Method)
DK (1) DK2504331T3 (en:Method)
ES (1) ES2529105T3 (en:Method)
IN (1) IN2012DN04868A (en:Method)
MX (1) MX2012005926A (en:Method)
MY (1) MY161749A (en:Method)
NZ (1) NZ600266A (en:Method)
PH (1) PH12012500992A1 (en:Method)
PL (1) PL2504331T3 (en:Method)
PT (1) PT2504331E (en:Method)
RU (1) RU2507203C1 (en:Method)
WO (1) WO2011060746A1 (en:Method)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102070618B (zh) 2009-11-23 2013-08-21 和记黄埔医药（上海）有限公司 一种化合物及其晶体
JP6619756B2 (ja) * 2014-06-19 2019-12-11 メリアル インコーポレイテッド インドール誘導体を含む殺寄生虫性組成物、寄生虫駆除方法及びこれらの使用
CN105985326B (zh) * 2015-02-16 2020-04-14 上海宣创生物科技有限公司 嘧啶衍生物晶型ⅲ及其制备方法和用途
WO2016187767A1 (en) * 2015-05-25 2016-12-01 Hutchison Medipharma Limited Pharmaceutical compositions and use thereof
US20190276439A1 (en) * 2016-11-18 2019-09-12 Hutchison Medipharma Limited Method of treating solid tumors
JP2020164434A (ja) * 2019-03-28 2020-10-08 上野製薬株式会社 ２，６−ナフタレンビス（２−オキサゾリン）の製造方法
WO2021180027A1 (zh) * 2020-03-09 2021-09-16 和记黄埔医药（上海）有限公司 抗pd-1抗体和多受体酪氨酸激酶抑制剂的药物组合及其使用方法
JP2024515630A (ja) * 2021-04-12 2024-04-10 ミトイミューン・セラピューティクス・インコーポレイテッド ５－［（１，１－ジオキシド－４－チオモルホリニル）メチル］－２－フェニル－ｎ－（テトラヒドロ－２ｈ－ピラン－４－イル）－１ｈ－インドール－７－アミンの新規結晶形

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2558915A1 (en) * 2004-03-30 2005-10-13 Taisho Pharmaceutical Co., Ltd. Pyrimidine derivatives and methods of treatment related to the use thereof
EP1934200A1 (en) 2005-09-15 2008-06-25 Merck & Co., Inc. Tyrosine kinase inhibitors
BRPI0809715A2 (pt) * 2007-04-16 2019-11-05 Hutchison Medipharma Entpr Ltd "composto, método de tratamento de um distúrbio relacionado com a angiogênese,método de inibição da atividade de receptor de domínio de inserto de quinase, método de inibição de angiogênese e método de tratamento de degeneração macular"
CN101289444B (zh) * 2007-04-16 2012-01-04 和记黄埔医药（上海）有限公司 一种嘧啶衍生物及其医药用途
US7737157B2 (en) * 2008-08-29 2010-06-15 Hutchison Medipharma Enterprises Limited Pyrimidine compounds
CN102070618B (zh) 2009-11-23 2013-08-21 和记黄埔医药（上海）有限公司 一种化合物及其晶体

Also Published As

Publication number Publication date
EP2504331B1 (en) 2014-11-12
CN102648194B (zh) 2014-10-29
DK2504331T3 (en) 2014-12-08
KR20120097526A (ko) 2012-09-04
ES2529105T3 (es) 2015-02-16
IN2012DN04868A (en:Method) 2015-09-25
CN102648194A (zh) 2012-08-22
US20140200232A1 (en) 2014-07-17
CN102070618B (zh) 2013-08-21
MX2012005926A (es) 2012-11-23
BR112012012138A2 (pt) 2017-03-07
NZ600266A (en) 2014-06-27
AU2010321366A1 (en) 2012-06-14
EP2504331A1 (en) 2012-10-03
JP2013511475A (ja) 2013-04-04
CN102070618A (zh) 2011-05-25
AU2010321366B2 (en) 2014-07-24
US8946249B2 (en) 2015-02-03
PT2504331E (pt) 2015-02-20
US8658658B2 (en) 2014-02-25
EP2504331A4 (en) 2013-04-17
PL2504331T3 (pl) 2015-04-30
US20120270889A1 (en) 2012-10-25
JP5758399B2 (ja) 2015-08-05
RU2507203C1 (ru) 2014-02-20
CA2781066C (en) 2014-09-16
CA2781066A1 (en) 2011-05-26
RU2012126112A (ru) 2013-12-27
WO2011060746A1 (en) 2011-05-26
BR112012012138B1 (pt) 2023-02-07
AU2010321366A8 (en) 2012-07-05
KR101513784B1 (ko) 2015-04-20
MY161749A (en) 2017-05-15

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