PH10281A - Process for 11alpha-dehalogenation of 11alpha-halotetracyclines - Google Patents

Process for 11alpha-dehalogenation of 11alpha-halotetracyclines

Info

Publication number
PH10281A
PH10281A PH15857*A PH15857A PH10281A PH 10281 A PH10281 A PH 10281A PH 15857 A PH15857 A PH 15857A PH 10281 A PH10281 A PH 10281A
Authority
PH
Philippines
Prior art keywords
11alpha
halotetracyclines
dehalogenation
Prior art date
Application number
PH15857*A
Other languages
English (en)
Inventor
H Faubl
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PH10281A publication Critical patent/PH10281A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PH15857*A 1973-06-21 1974-05-23 Process for 11alpha-dehalogenation of 11alpha-halotetracyclines PH10281A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37230873A 1973-06-21 1973-06-21

Publications (1)

Publication Number Publication Date
PH10281A true PH10281A (en) 1976-11-05

Family

ID=23467606

Family Applications (1)

Application Number Title Priority Date Filing Date
PH15857*A PH10281A (en) 1973-06-21 1974-05-23 Process for 11alpha-dehalogenation of 11alpha-halotetracyclines

Country Status (30)

Country Link
US (1) US4126639A (de)
JP (1) JPS5719095B2 (de)
AT (1) AT337358B (de)
BE (1) BE815776A (de)
CA (1) CA1110618A (de)
CH (1) CH585696A5 (de)
CS (1) CS175380B2 (de)
DD (1) DD113893A5 (de)
DE (1) DE2427420C2 (de)
DK (1) DK153756C (de)
ES (1) ES426893A1 (de)
FI (1) FI58631C (de)
FR (1) FR2234272B1 (de)
GB (1) GB1459861A (de)
HK (1) HK26879A (de)
HU (1) HU169605B (de)
IE (1) IE39758B1 (de)
IL (1) IL44875A (de)
KE (1) KE2929A (de)
LU (1) LU70248A1 (de)
MY (1) MY7900232A (de)
NL (1) NL179476C (de)
NO (1) NO146597C (de)
PH (1) PH10281A (de)
PL (1) PL89987B1 (de)
RO (1) RO67373A (de)
SE (1) SE416646B (de)
SU (1) SU512698A3 (de)
YU (1) YU39461B (de)
ZA (1) ZA743341B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU41093B (en) * 1978-04-12 1986-12-31 Pliva Pharm & Chem Works Process for preparing 6-deoxy-5hydroxy-tetracycline
DK386784A (da) * 1983-08-17 1985-02-18 Hovione Int Ltd Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2742510A (en) * 1955-06-17 1956-04-17 Kellogg M W Co Process for dehalogenation of organic compounds
US3043875A (en) * 1959-10-22 1962-07-10 Pfizer & Co C Halogenated tetracycline derivatives and processes for their preparation
FR1430859A (de) * 1960-05-23 1966-05-25
US3250809A (en) * 1962-09-06 1966-05-10 Pfizer & Co C 6-deoxy-6-demethyl-6-halomethylene tetracyclines and their 11a-chloro and fluoro derivatives
NL128202C (de) * 1964-01-21
DE1245360B (de) * 1965-11-17 1967-07-27 Knapsack Ag Verfahren zur Herstellung eines aus 1,2-Dichlorbuten-(2), 1, 3-Dichlorbuten-(2) und 2 ,3-Dichlorbuten-(1) bestehenden Gemisches
US3484483A (en) * 1966-10-31 1969-12-16 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
US3649700A (en) * 1966-12-20 1972-03-14 Knapsack Ag Process for the dehydrochlorination of chlorinated hydrocarbons
US3444198A (en) * 1967-02-13 1969-05-13 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
CA942743A (en) * 1970-07-03 1974-02-26 Ivan Villax Process for producing 6-methylenetetracyclines and 6-deoxytetracyclines
GB1349043A (en) * 1971-04-05 1974-03-27 Pliva Pharm & Chem Works Process for the preparation of 6-demethyl-6-deoxy-6-methylene tetracyclines

Also Published As

Publication number Publication date
GB1459861A (en) 1976-12-31
SE7406228L (de) 1974-12-23
FI58631B (fi) 1980-11-28
SU512698A3 (ru) 1976-04-30
CH585696A5 (de) 1977-03-15
DK298074A (de) 1975-02-10
FI58631C (fi) 1981-03-10
FR2234272B1 (de) 1977-07-01
ZA743341B (en) 1975-05-28
FI168774A (de) 1974-12-22
SE416646B (sv) 1981-01-26
NO146597B (no) 1982-07-26
NL7407368A (de) 1974-12-24
IL44875A0 (en) 1974-07-31
US4126639A (en) 1978-11-21
IE39758L (en) 1974-12-21
BE815776A (fr) 1974-12-02
JPS5719095B2 (de) 1982-04-20
HK26879A (en) 1979-05-04
AU6940974A (en) 1975-11-27
RO67373A (ro) 1980-03-15
CS175380B2 (de) 1977-05-31
IL44875A (en) 1977-04-29
DE2427420A1 (de) 1975-01-30
HU169605B (de) 1976-12-28
DK153756B (da) 1988-08-29
JPS5019746A (de) 1975-03-01
YU151174A (en) 1982-05-31
PL89987B1 (de) 1976-12-31
DK153756C (da) 1989-01-09
FR2234272A1 (de) 1975-01-17
NO742004L (de) 1975-01-20
MY7900232A (en) 1979-12-31
ES426893A1 (es) 1976-07-16
AT337358B (de) 1977-06-27
LU70248A1 (de) 1975-03-06
NL179476B (nl) 1986-04-16
DE2427420C2 (de) 1987-02-05
YU39461B (en) 1984-12-31
KE2929A (en) 1979-03-30
ATA453674A (de) 1976-10-15
CA1110618A (en) 1981-10-13
DD113893A5 (de) 1975-07-05
NL179476C (nl) 1986-09-16
IE39758B1 (en) 1978-12-20
NO146597C (no) 1982-11-03

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