PE44199A1 - Benzo[e]isoindoles y benzo[h]isoquinolinas triciclicos - Google Patents
Benzo[e]isoindoles y benzo[h]isoquinolinas triciclicosInfo
- Publication number
- PE44199A1 PE44199A1 PE1998000005A PE00000598A PE44199A1 PE 44199 A1 PE44199 A1 PE 44199A1 PE 1998000005 A PE1998000005 A PE 1998000005A PE 00000598 A PE00000598 A PE 00000598A PE 44199 A1 PE44199 A1 PE 44199A1
- Authority
- PE
- Peru
- Prior art keywords
- benzo
- lower alkyl
- triciclicos
- isoindoles
- isoquinolines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE REFIEREN A COMPUESTOS DE FORMULA (I), EN DONDE: R1, R2, R3 Y R4 SON H, HALOGENO, OH, ALQUILO INFERIOR, ALCOXILO INFERIOR o FENILO; o R2 Y R3 JUNTOS SON -O-CH2-O-; R5 ES H, ALQUILO INFERIOR o BENCILO; n ES 0 o 1; CON LA CONDICION DE QUE EL COMPUESTO (I) NO ES 2-METIL-1,3,4,4a,5,10b-HEXAHIDRO-2H-BENZO[H]ISOQUINOLIN-6-ONA RACEMICA. TAMBIEN SE REFIERE A SU PROCEDIMIENTO DE PREPARACION. LOS COMPUESTOS DE FORMULA (I) ACTUAN UNIENDOSE A LOS RECEPTORES (5HT2) DE SEROTONINA, SIENDO UTILES EN EL TRATAMIENTO O PREVENCION DE TRASTORNOS DEL SISTEMA NERVIOSO CENTRAL TALES COMO DEPRESION, ANSIEDAD, INSOMNIO, PSICOSIS, ENTRE OTROS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97100172 | 1997-01-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE44199A1 true PE44199A1 (es) | 1999-05-06 |
Family
ID=8226353
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1998000005A PE44199A1 (es) | 1997-01-08 | 1998-01-05 | Benzo[e]isoindoles y benzo[h]isoquinolinas triciclicos |
Country Status (12)
Country | Link |
---|---|
US (1) | US6310208B1 (es) |
KR (1) | KR100433609B1 (es) |
CN (1) | CN1113872C (es) |
AR (1) | AR011358A1 (es) |
CO (1) | CO4930268A1 (es) |
ES (1) | ES2212264T3 (es) |
HR (1) | HRP980003A2 (es) |
MA (1) | MA26461A1 (es) |
PE (1) | PE44199A1 (es) |
PT (1) | PT958285E (es) |
TR (1) | TR199901586T2 (es) |
ZA (1) | ZA9817B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2400300A1 (en) | 2004-08-25 | 2011-12-28 | Takeda Pharmaceutical Company Limited | Method of screening preventives/remedies for stress urinary incontinence |
EP2727585A1 (en) | 2006-05-16 | 2014-05-07 | Takeda Pharmaceutical Company Limited | In-vivo screening method |
US20100266504A1 (en) | 2007-11-15 | 2010-10-21 | Takahiro Matsumoto | Condensed pyridine derivative and use thereof |
CN101648865B (zh) * | 2008-08-16 | 2013-03-20 | 重庆市科学技术研究院 | 多酚丙烯酸衍生物及其在药物中的应用 |
JPWO2011071136A1 (ja) | 2009-12-11 | 2013-04-22 | アステラス製薬株式会社 | 線維筋痛症治療剤 |
WO2011097797A1 (zh) * | 2010-02-10 | 2011-08-18 | Peng Jinlian | 多酚丙烯酸衍生物,其制备方法以及在制备药物中的应用 |
EP3733204A4 (en) | 2017-12-27 | 2021-09-15 | Takeda Pharmaceutical Company Limited | THERAPEUTIC FOR EXERCISE INCONTINENCE AND STAIR INCONTINENCE |
CN112028878A (zh) * | 2020-09-11 | 2020-12-04 | 江阴迈康升华医药科技有限公司 | 一种多氢异喹啉衍生物及其制备方法和医疗用途 |
WO2022221774A1 (en) * | 2021-04-16 | 2022-10-20 | Eleusis Therapeutics Us, Inc. | Aryl-ring-substituted 3-phenylazetidines and their use in methods for treating 5-ht2 responsive conditions |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH504438A (de) | 1968-05-27 | 1971-03-15 | Sandoz Ag | Verfahren zur Herstellung von 1,2,3,4,4a,5,6,10b-Octahydrobenz(h)isochinolin-6-on |
US4678791A (en) | 1985-05-07 | 1987-07-07 | Pennwalt Corporation | 6-phenyl-1,2-3,4,4a,5-6,10b-octahydrobenz(h)isoquinolines useful for treating depression |
JPH03101658A (ja) * | 1989-09-13 | 1991-04-26 | Nippon Chemiphar Co Ltd | ピロリジン酢酸誘導体 |
US5180733A (en) | 1990-03-30 | 1993-01-19 | Abbott Laboratories | Biogenic amine uptake inhibitors |
-
1998
- 1998-01-02 MA MA24916A patent/MA26461A1/fr unknown
- 1998-01-02 ZA ZA9817A patent/ZA9817B/xx unknown
- 1998-01-05 AR ARP980100025A patent/AR011358A1/es unknown
- 1998-01-05 PE PE1998000005A patent/PE44199A1/es not_active Application Discontinuation
- 1998-01-06 US US09/003,446 patent/US6310208B1/en not_active Expired - Fee Related
- 1998-01-07 CO CO98000437A patent/CO4930268A1/es unknown
- 1998-01-07 ES ES98902982T patent/ES2212264T3/es not_active Expired - Lifetime
- 1998-01-07 TR TR1999/01586T patent/TR199901586T2/xx unknown
- 1998-01-07 CN CN98801734A patent/CN1113872C/zh not_active Expired - Fee Related
- 1998-01-07 KR KR10-1999-7006175A patent/KR100433609B1/ko not_active IP Right Cessation
- 1998-01-07 PT PT98902982T patent/PT958285E/pt unknown
- 1998-01-07 HR HR97100172.2A patent/HRP980003A2/hr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20000069962A (ko) | 2000-11-25 |
ES2212264T3 (es) | 2004-07-16 |
KR100433609B1 (ko) | 2004-05-31 |
CO4930268A1 (es) | 2000-06-27 |
TR199901586T2 (xx) | 1999-10-21 |
HRP980003A2 (en) | 1998-10-31 |
CN1113872C (zh) | 2003-07-09 |
MA26461A1 (fr) | 2004-12-20 |
AR011358A1 (es) | 2000-08-16 |
US6310208B1 (en) | 2001-10-30 |
PT958285E (pt) | 2004-05-31 |
CN1243510A (zh) | 2000-02-02 |
ZA9817B (en) | 1998-07-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |