PE34696A1 - Derivado de acetidinilalquil-lactama - Google Patents
Derivado de acetidinilalquil-lactamaInfo
- Publication number
- PE34696A1 PE34696A1 PE1995275289A PE27528995A PE34696A1 PE 34696 A1 PE34696 A1 PE 34696A1 PE 1995275289 A PE1995275289 A PE 1995275289A PE 27528995 A PE27528995 A PE 27528995A PE 34696 A1 PE34696 A1 PE 34696A1
- Authority
- PE
- Peru
- Prior art keywords
- alkyl
- cycloalkyl
- conr3r4
- preference
- direct link
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE REFIERE A UN COMPUESTO DE FORMULA I DONDE R ES CICLOALQUILO DE C3-C7, ARILO o ALQUILO DE C1-C6, ESTANDO DICHO ALQUILO DE C1-C6 OPCIONALMENTE SUSTITUIDO POR COOH, UN COMPUESTO PREFERIDO ES 5-CARBOXIPENTILO; R1 ES FENILO, NAFTILO, BENZOTIENILO ENTRE OTROS, CADA UNO SUSTITUIDO OPCIONALMENTE POR UNO o DOS SUSTITUYENTES CADA UNO SELECCIONADO INDEPENDIENTEMENTE DE ALQUILO DE C1-C4, ALCOXI DE C1-C4, HALO Y TRIFLUOROMETILO, DE PREFERENCIA HALO; R2 ES -CO2H, -CONR3R4,-CONR5 (CICLOALQUILO DE C3-C7) ENTRE OTROS, DE PREFERENCIA -CONR3R4; R3 Y R4 ESTAN SELECCIONADOS CADA UNO INDEPENDIENTEMENTE DE H y ALQUILO DE C1-C4 OPCIONALMENTE SUSTITUIDO POR OH, ALCOXI DE C1-C4, AMINO ENTRE OTROS; R5 Y R6 ESTAN SELECCIONADOS DE H, ALQUILO DE C1-C4, CICLOALQUILO DE C3-C7-ALQUILO DE C1-C4 ENTRE OTROS; X ES ALQUILENO DE C1-C4 DE PREFERENCIA ETILENO o PROPILENO; X1 ES UN ENLACE DIRECTO o ALQUILENO DE C1-C6, DE PREFERENCIA ENLACE DIRECTO; m ES 0, 1 o 2. ES USADO EN EL TRATAMIENTO DE UNA ENFERMEDAD INFLAMATORIA TAL COMO ARTRITIS, PSORIASIS, ASMA, ENTRE OTRAS, PRODUCIENDO UN EFECTO ANTAGONISTA SOBRE UNA TAQUICININA QUE ACTUA EN EL RECEPTOR HUMANO NK1, NK2, NK3 o COMBINACION DE ELLAS
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9416084A GB9416084D0 (en) | 1994-08-09 | 1994-08-09 | Lactams |
GB9417898A GB9417898D0 (en) | 1994-08-09 | 1994-09-06 | Lactams |
Publications (1)
Publication Number | Publication Date |
---|---|
PE34696A1 true PE34696A1 (es) | 1996-10-01 |
Family
ID=10759627
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1995275289A PE34696A1 (es) | 1994-08-09 | 1995-08-03 | Derivado de acetidinilalquil-lactama |
Country Status (5)
Country | Link |
---|---|
KR (1) | KR100218626B1 (es) |
CO (1) | CO4410338A1 (es) |
GB (2) | GB9416084D0 (es) |
PE (1) | PE34696A1 (es) |
PL (1) | PL183180B1 (es) |
-
1994
- 1994-08-09 GB GB9416084A patent/GB9416084D0/en active Pending
- 1994-09-06 GB GB9417898A patent/GB9417898D0/en active Pending
-
1995
- 1995-07-29 KR KR1019970700816A patent/KR100218626B1/ko not_active IP Right Cessation
- 1995-07-29 PL PL95318534A patent/PL183180B1/pl unknown
- 1995-08-03 PE PE1995275289A patent/PE34696A1/es not_active Application Discontinuation
- 1995-08-08 CO CO95035201A patent/CO4410338A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
GB9417898D0 (en) | 1994-10-26 |
PL318534A1 (en) | 1997-06-23 |
KR100218626B1 (ko) | 1999-09-01 |
KR970704729A (ko) | 1997-09-06 |
GB9416084D0 (en) | 1994-09-28 |
PL183180B1 (pl) | 2002-05-31 |
CO4410338A1 (es) | 1997-01-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed |