FI834730A - 1-karboxialkanoylperhydro-indol-2- karboxylsyror och deras derivat. - Google Patents

1-karboxialkanoylperhydro-indol-2- karboxylsyror och deras derivat. Download PDF

Info

Publication number
FI834730A
FI834730A FI834730A FI834730A FI834730A FI 834730 A FI834730 A FI 834730A FI 834730 A FI834730 A FI 834730A FI 834730 A FI834730 A FI 834730A FI 834730 A FI834730 A FI 834730A
Authority
FI
Finland
Prior art keywords
carboxylsyror
carboxykanoylperhydro
indol
och deras
derivat
Prior art date
Application number
FI834730A
Other languages
English (en)
Other versions
FI834730A0 (fi
Inventor
Norbert Gruenfeld
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI834730A publication Critical patent/FI834730A/fi
Publication of FI834730A0 publication Critical patent/FI834730A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/89Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI834730A 1982-04-26 1983-12-22 1-karboxialkanoylperhydro-indol-2-karboxylsyror och deras derivat FI834730A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/371,700 US4479963A (en) 1981-02-17 1982-04-26 1-Carboxyalkanoylindoline-2-carboxylic acids
PCT/US1983/000597 WO1983003828A1 (en) 1982-04-26 1983-04-25 1-carboxyalkanoylperhydroindole-2-carboxylic acids and derivatives

Publications (2)

Publication Number Publication Date
FI834730A true FI834730A (fi) 1983-12-22
FI834730A0 FI834730A0 (fi) 1983-12-22

Family

ID=23465059

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834730A FI834730A0 (fi) 1982-04-26 1983-12-22 1-karboxialkanoylperhydro-indol-2-karboxylsyror och deras derivat

Country Status (11)

Country Link
US (1) US4479963A (fi)
EP (2) EP0093084B1 (fi)
JP (1) JPS58194859A (fi)
AT (1) ATE18549T1 (fi)
AU (1) AU1395283A (fi)
CA (1) CA1199911A (fi)
DE (2) DE3362504D1 (fi)
DK (1) DK182783A (fi)
FI (1) FI834730A0 (fi)
WO (1) WO1983003828A1 (fi)
ZA (1) ZA832887B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0798802B2 (ja) * 1984-07-13 1995-10-25 東レ株式会社 光学活性インドリン―2―カルボン酸の製造法
JPS6137764A (ja) * 1984-07-31 1986-02-22 Suntory Ltd 抗プロリルエンドペプチダ−ゼ活性を有する新規生理活性化合物
JPH0623190B2 (ja) * 1985-04-16 1994-03-30 サントリー株式会社 インヒビタ−活性を有するn−アシルピロリジン誘導体及びその製法並びに用途
FR2620703B1 (fr) * 1987-09-17 1991-10-04 Adir Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides
FR2679903B1 (fr) * 1991-08-02 1993-12-03 Elf Sanofi Derives de la n-sulfonyl indoline portant une fonction amidique, leur preparation, les compositions pharmaceutiques en contenant.
US5338755A (en) * 1990-07-31 1994-08-16 Elf Sanofi N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present
US5481005A (en) * 1990-07-31 1996-01-02 Sanofi N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present
FR2665441B1 (fr) * 1990-07-31 1992-12-04 Sanofi Sa Derives de la n-sulfonyl indoline, leur preparation, les compositions pharmaceutiques en contenant.
AU654331B2 (en) * 1991-03-30 1994-11-03 Kissei Pharmaceutical Co. Ltd. Succinic acid compounds
AU7381196A (en) * 1995-09-28 1997-04-17 Merck & Co., Inc. Preparation of carboxyalkyl derivatives
US6043389A (en) 1997-03-11 2000-03-28 Mor Research Applications, Ltd. Hydroxy and ether-containing oxyalkylene esters and uses thereof
US5939455A (en) * 1997-03-11 1999-08-17 Beacon Laboratories, Inc. Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
JP6487752B2 (ja) * 2015-03-31 2019-03-20 大阪瓦斯株式会社 ジカルボン酸又はエステル及びそれを用いた樹脂並びにそれらの製造方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3974145A (en) * 1970-08-26 1976-08-10 Sumitomo Chemical Company, Limited Novel N'-acylated phenyl-hydrazine and hydrozone derivatives
CH542201A (de) * 1970-10-30 1973-09-30 Hoffmann La Roche Verfahren zur Herstellung von Indolinderivaten
CH547799A (de) * 1970-10-30 1974-04-11 Hoffmann La Roche Verfahren zur herstellung von indolinderivaten.
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
US4052511A (en) * 1976-02-13 1977-10-04 E. R. Squibb & Sons, Inc. Carboxyacylproline derivatives
US4154937A (en) * 1977-02-11 1979-05-15 E. R. Squibb & Sons, Inc. Hydroxycarbamoylalkylacylpipecolic acid compounds
US4303583A (en) * 1979-08-13 1981-12-01 American Home Products Corporation 1H,5H-[1,4]Thiazepino[4,3-a]indole-1,5-diones
FR2487829A2 (fr) * 1979-12-07 1982-02-05 Science Union & Cie Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
FR2503155A2 (fr) * 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
FR2470767A1 (fr) * 1979-12-07 1981-06-12 Science Union & Cie Nouveaux iminoacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzymes
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
US4350633A (en) * 1980-07-01 1982-09-21 American Home Products Corporation N-(2-Substituted-1-oxoalkyl)-2,3-dihydro-1H-indole-2-carboxylic acid derivatives
DE3177311D1 (de) * 1980-08-30 1994-06-09 Hoechst Ag Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung.
US4311705A (en) * 1980-10-06 1982-01-19 E. R. Squibb & Sons, Inc. Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
US4724265A (en) * 1986-05-15 1988-02-09 Stauffer Chemical Company Process for preparing liquid triaryl thiophosphate mixtures

Also Published As

Publication number Publication date
JPS58194859A (ja) 1983-11-12
DE3362504D1 (en) 1986-04-17
EP0105919B1 (en) 1987-07-08
EP0093084B1 (de) 1986-03-12
US4479963A (en) 1984-10-30
EP0093084A1 (de) 1983-11-02
ATE18549T1 (de) 1986-03-15
DK182783A (da) 1983-10-27
DK182783D0 (da) 1983-04-25
WO1983003828A1 (en) 1983-11-10
ZA832887B (en) 1983-12-28
AU1395283A (en) 1983-11-03
FI834730A0 (fi) 1983-12-22
DE3372364D1 (en) 1987-08-13
EP0105919A1 (en) 1984-04-25
CA1199911A (en) 1986-01-28

Similar Documents

Publication Publication Date Title
FI852974A0 (fi) Nya n-hydroxylgruppen skyddande grupper och framstaellningsfoerfarande foer 3-acylamino-1-hydroxi-2-azetidinoner.
ATE126517T1 (de) Verwendung von bis(3,4- dialkylbenzyliden)sorbitolacetale und diese enthaltende zusammensetzungen.
SE7906722L (sv) Merkaptoacylderivat av substituerade proliner
PL216409A1 (fi)
FI823923A0 (fi) Antifibrinolytiskt aktiva foereningar
FI834730A (fi) 1-karboxialkanoylperhydro-indol-2- karboxylsyror och deras derivat.
ATE93232T1 (de) Bis(methylendioxy)biphenyl-verbindungen.
DK0382660T3 (da) Dioxaphosphorinanforbindelser og dermed stabiliserede polyolefinmaterialer
ES8107001A1 (es) Un metodo de preparar nuevas diaminas
ATE99866T1 (de) Verwendung von 2,2,6,6-tetramethyl-4aminopiperidinamiden als fungizide.
ES8504176A1 (es) Un procedimiento para preparar derivados de esteres del acido propanoico
FI892681A0 (fi) Nya jodade icke-joniska trijodbenzenfoereningar och dessa innehaollande kontrastmedel.
ATE18044T1 (de) Substituierte thiazolidinylester von mineralsaeuren.
ES516361A0 (es) "procedimiento para la preparacion de un diisocianato".
FI843617A0 (fi) 4-(2-alkynyloxi-2-hydroxipropyl)- piperazin-1-yl-n-fenyl-acetamidderivat.
DK384388D0 (da) Herbicid
ES8100238A1 (es) Un procedimiento para la preparacion de derivados del acido oxisustituido-ciclohexilacetico
BG35896A3 (en) Method for preparing 3- halogen- 3- cephem compounds
ATE23147T1 (de) Ungesaettigte verbindungen, ihre herstellung und anwendung.
FI824407L (fi) Foerfarande foer framstaellning av vid behandling av magsaor anvaendbara pyrimidinderivat
ES8503646A1 (es) Procedimiento para la obtencion de derivados de bencilurea.
FI840005A0 (fi) Triorganotenn-acetylsalicylat och dessa innehaollande biocida aemnen
ES8504688A1 (es) Procedimiento para la obtencion de esteres del acido halogenoalquilcarbamico
DK300183D0 (da) Fremgangsmade til fremstilling af antiallergiske pyrazin-bis-(2-oxoglycin) forbindelser
SE8302972L (sv) Nya karbamidkompositioner

Legal Events

Date Code Title Description
FD Application lapsed

Owner name: CIBA-GEIGY AG