ZA832887B - 1-carboxyalkanoylindoline-2-carboxylic acid esters - Google Patents
1-carboxyalkanoylindoline-2-carboxylic acid estersInfo
- Publication number
- ZA832887B ZA832887B ZA832887A ZA832887A ZA832887B ZA 832887 B ZA832887 B ZA 832887B ZA 832887 A ZA832887 A ZA 832887A ZA 832887 A ZA832887 A ZA 832887A ZA 832887 B ZA832887 B ZA 832887B
- Authority
- ZA
- South Africa
- Prior art keywords
- carboxyalkanoylindoline
- carboxylic acid
- acid esters
- lower alkyl
- esters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/89—Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/371,700 US4479963A (en) | 1981-02-17 | 1982-04-26 | 1-Carboxyalkanoylindoline-2-carboxylic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA832887B true ZA832887B (en) | 1983-12-28 |
Family
ID=23465059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA832887A ZA832887B (en) | 1982-04-26 | 1983-04-25 | 1-carboxyalkanoylindoline-2-carboxylic acid esters |
Country Status (11)
Country | Link |
---|---|
US (1) | US4479963A (fi) |
EP (2) | EP0093084B1 (fi) |
JP (1) | JPS58194859A (fi) |
AT (1) | ATE18549T1 (fi) |
AU (1) | AU1395283A (fi) |
CA (1) | CA1199911A (fi) |
DE (2) | DE3362504D1 (fi) |
DK (1) | DK182783A (fi) |
FI (1) | FI834730A0 (fi) |
WO (1) | WO1983003828A1 (fi) |
ZA (1) | ZA832887B (fi) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0798802B2 (ja) * | 1984-07-13 | 1995-10-25 | 東レ株式会社 | 光学活性インドリン―2―カルボン酸の製造法 |
JPS6137764A (ja) * | 1984-07-31 | 1986-02-22 | Suntory Ltd | 抗プロリルエンドペプチダ−ゼ活性を有する新規生理活性化合物 |
JPH0623190B2 (ja) * | 1985-04-16 | 1994-03-30 | サントリー株式会社 | インヒビタ−活性を有するn−アシルピロリジン誘導体及びその製法並びに用途 |
FR2620703B1 (fr) * | 1987-09-17 | 1991-10-04 | Adir | Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides |
FR2679903B1 (fr) * | 1991-08-02 | 1993-12-03 | Elf Sanofi | Derives de la n-sulfonyl indoline portant une fonction amidique, leur preparation, les compositions pharmaceutiques en contenant. |
US5338755A (en) * | 1990-07-31 | 1994-08-16 | Elf Sanofi | N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present |
US5481005A (en) * | 1990-07-31 | 1996-01-02 | Sanofi | N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present |
FR2665441B1 (fr) * | 1990-07-31 | 1992-12-04 | Sanofi Sa | Derives de la n-sulfonyl indoline, leur preparation, les compositions pharmaceutiques en contenant. |
AU654331B2 (en) * | 1991-03-30 | 1994-11-03 | Kissei Pharmaceutical Co. Ltd. | Succinic acid compounds |
AU7381196A (en) * | 1995-09-28 | 1997-04-17 | Merck & Co., Inc. | Preparation of carboxyalkyl derivatives |
US6043389A (en) | 1997-03-11 | 2000-03-28 | Mor Research Applications, Ltd. | Hydroxy and ether-containing oxyalkylene esters and uses thereof |
US5939455A (en) * | 1997-03-11 | 1999-08-17 | Beacon Laboratories, Inc. | Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives |
JP6487752B2 (ja) * | 2015-03-31 | 2019-03-20 | 大阪瓦斯株式会社 | ジカルボン酸又はエステル及びそれを用いた樹脂並びにそれらの製造方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3974145A (en) * | 1970-08-26 | 1976-08-10 | Sumitomo Chemical Company, Limited | Novel N'-acylated phenyl-hydrazine and hydrozone derivatives |
CH542201A (de) * | 1970-10-30 | 1973-09-30 | Hoffmann La Roche | Verfahren zur Herstellung von Indolinderivaten |
CH547799A (de) * | 1970-10-30 | 1974-04-11 | Hoffmann La Roche | Verfahren zur herstellung von indolinderivaten. |
US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
US4052511A (en) * | 1976-02-13 | 1977-10-04 | E. R. Squibb & Sons, Inc. | Carboxyacylproline derivatives |
US4154937A (en) * | 1977-02-11 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Hydroxycarbamoylalkylacylpipecolic acid compounds |
US4303583A (en) * | 1979-08-13 | 1981-12-01 | American Home Products Corporation | 1H,5H-[1,4]Thiazepino[4,3-a]indole-1,5-diones |
FR2487829A2 (fr) * | 1979-12-07 | 1982-02-05 | Science Union & Cie | Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme |
FR2503155A2 (fr) * | 1980-10-02 | 1982-10-08 | Science Union & Cie | Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme |
FR2470767A1 (fr) * | 1979-12-07 | 1981-06-12 | Science Union & Cie | Nouveaux iminoacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzymes |
IE52663B1 (en) * | 1980-04-02 | 1988-01-20 | Warner Lambert Co | Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids |
US4350633A (en) * | 1980-07-01 | 1982-09-21 | American Home Products Corporation | N-(2-Substituted-1-oxoalkyl)-2,3-dihydro-1H-indole-2-carboxylic acid derivatives |
DE3177311D1 (de) * | 1980-08-30 | 1994-06-09 | Hoechst Ag | Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung. |
US4311705A (en) * | 1980-10-06 | 1982-01-19 | E. R. Squibb & Sons, Inc. | Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines |
US4374847A (en) * | 1980-10-27 | 1983-02-22 | Ciba-Geigy Corporation | 1-Carboxyalkanoylindoline-2-carboxylic acids |
US4724265A (en) * | 1986-05-15 | 1988-02-09 | Stauffer Chemical Company | Process for preparing liquid triaryl thiophosphate mixtures |
-
1982
- 1982-04-26 US US06/371,700 patent/US4479963A/en not_active Expired - Fee Related
-
1983
- 1983-04-20 DE DE8383810166T patent/DE3362504D1/de not_active Expired
- 1983-04-20 EP EP83810166A patent/EP0093084B1/de not_active Expired
- 1983-04-20 AT AT83810166T patent/ATE18549T1/de not_active IP Right Cessation
- 1983-04-22 CA CA000426482A patent/CA1199911A/en not_active Expired
- 1983-04-25 DK DK182783A patent/DK182783A/da not_active Application Discontinuation
- 1983-04-25 EP EP83901683A patent/EP0105919B1/en not_active Expired
- 1983-04-25 ZA ZA832887A patent/ZA832887B/xx unknown
- 1983-04-25 JP JP58071556A patent/JPS58194859A/ja active Pending
- 1983-04-25 DE DE8383901683T patent/DE3372364D1/de not_active Expired
- 1983-04-25 WO PCT/US1983/000597 patent/WO1983003828A1/en active IP Right Grant
- 1983-04-26 AU AU13952/83A patent/AU1395283A/en not_active Abandoned
- 1983-12-22 FI FI834730A patent/FI834730A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPS58194859A (ja) | 1983-11-12 |
DE3362504D1 (en) | 1986-04-17 |
EP0105919B1 (en) | 1987-07-08 |
EP0093084B1 (de) | 1986-03-12 |
US4479963A (en) | 1984-10-30 |
EP0093084A1 (de) | 1983-11-02 |
ATE18549T1 (de) | 1986-03-15 |
DK182783A (da) | 1983-10-27 |
FI834730A (fi) | 1983-12-22 |
DK182783D0 (da) | 1983-04-25 |
WO1983003828A1 (en) | 1983-11-10 |
AU1395283A (en) | 1983-11-03 |
FI834730A0 (fi) | 1983-12-22 |
DE3372364D1 (en) | 1987-08-13 |
EP0105919A1 (en) | 1984-04-25 |
CA1199911A (en) | 1986-01-28 |
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