PE20231748A1 - ANTICUERPOS ANTI-N3pGlu BETA AMILOIDE Y USOS DE ESTOS - Google Patents

ANTICUERPOS ANTI-N3pGlu BETA AMILOIDE Y USOS DE ESTOS

Info

Publication number
PE20231748A1
PE20231748A1 PE2023002030A PE2023002030A PE20231748A1 PE 20231748 A1 PE20231748 A1 PE 20231748A1 PE 2023002030 A PE2023002030 A PE 2023002030A PE 2023002030 A PE2023002030 A PE 2023002030A PE 20231748 A1 PE20231748 A1 PE 20231748A1
Authority
PE
Peru
Prior art keywords
n3pglu
beta amyloid
amyloid antibodies
seq
amino acid
Prior art date
Application number
PE2023002030A
Other languages
English (en)
Spanish (es)
Inventor
Adam S Fleisher
Mark Mintun
John Randall Ii Sims
Jondavid Sparks
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PE20231748A1 publication Critical patent/PE20231748A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PE2023002030A 2021-01-11 2022-01-11 ANTICUERPOS ANTI-N3pGlu BETA AMILOIDE Y USOS DE ESTOS PE20231748A1 (es)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202163135932P 2021-01-11 2021-01-11
US202163155029P 2021-03-01 2021-03-01
US202163160380P 2021-03-12 2021-03-12
US202163192262P 2021-05-24 2021-05-24
US202163227054P 2021-07-29 2021-07-29
US202163277298P 2021-11-09 2021-11-09
US202163284248P 2021-11-30 2021-11-30
US202263296694P 2022-01-05 2022-01-05
PCT/US2022/011894 WO2022150735A1 (en) 2021-01-11 2022-01-11 Anti-n3pglu amyloid beta antibodies and uses thereof

Publications (1)

Publication Number Publication Date
PE20231748A1 true PE20231748A1 (es) 2023-11-06

Family

ID=80123357

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2023002030A PE20231748A1 (es) 2021-01-11 2022-01-11 ANTICUERPOS ANTI-N3pGlu BETA AMILOIDE Y USOS DE ESTOS

Country Status (15)

Country Link
US (1) US20240010713A1 (https=)
EP (1) EP4274611A1 (https=)
JP (2) JP7676556B2 (https=)
KR (2) KR20260047659A (https=)
AU (1) AU2022206461B2 (https=)
CA (1) CA3204444A1 (https=)
CL (1) CL2023001992A1 (https=)
CO (1) CO2023009089A2 (https=)
EC (1) ECSP23051813A (https=)
IL (1) IL304072A (https=)
MX (1) MX2023008196A (https=)
PE (1) PE20231748A1 (https=)
TW (1) TWI843040B (https=)
WO (1) WO2022150735A1 (https=)
ZA (1) ZA202306180B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022307687A1 (en) * 2021-07-09 2024-01-04 Eisai R&D Management Co., Ltd. Biomarkers for alzheimer's disease treatment
WO2023039107A2 (en) 2021-09-09 2023-03-16 Alzpath, Inc. Phospho-tau antibodies and methods of use
CA3243602A1 (en) * 2022-02-03 2023-08-10 Eli Lilly And Company Regional Tau Imaging for the Diagnosis and Treatment of Alzheimer's Disease
KR20250107906A (ko) * 2022-11-17 2025-07-14 일라이 릴리 앤드 캄파니 항-N3pGlu 아밀로이드 베타 항체, 그의 용량 및 용도
KR20250173598A (ko) * 2023-03-16 2025-12-10 알즈패스, 인크. 신경퇴행성 질환의 진단 및 치료 방법
WO2025231343A1 (en) * 2024-05-03 2025-11-06 Therini Bio, Inc. Doses of antibodies which bind human fibrin yc or fibrinogen yc domain for neurodegenerative diseases
WO2025240435A1 (en) * 2024-05-14 2025-11-20 Othair Prothena Limited Methods of treating neurological disorders with anti-abeta antibodies

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1257584T1 (de) 2000-02-24 2003-05-28 Lilly Co Eli Humanisierte antikörper, die amyloid beta peptid demarkieren
PT1944040E (pt) 2001-08-17 2012-10-31 Univ Washington Método de avaliação para a doença de alzheimer
SI1720909T1 (sl) 2004-02-23 2012-01-31 Lilly Co Eli Anti-abeta protitelo
WO2010009987A2 (en) 2008-07-21 2010-01-28 Probiodrug Ag Diagnostic antibody assay
WO2011151076A2 (en) 2010-06-04 2011-12-08 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin MONOCLONAL ANTIBODIES TARGETING Αβ OLIGOMERS
PL3042917T3 (pl) 2010-08-12 2018-07-31 Eli Lilly And Company Przeciwciała przeciwko peptydowi beta amyloidu N3pGlu i ich zastosowanie
WO2012021475A2 (en) * 2010-08-12 2012-02-16 Eli Lilly And Company ANTI-N3pGlu AMYLOID BETA PEPTIDE ANTIBODIES AND USES THEREOF
US9499610B2 (en) 2011-04-08 2016-11-22 H. Lundbeck A/S Antibodies specific to pyroglutamated Aβ
JOP20170004B1 (ar) 2016-01-15 2022-09-15 Lilly Co Eli الأجسام المضادة لببتيد بيتا النشوي مضاد N3pGlu واستخداماته
TWI798751B (zh) * 2016-07-01 2023-04-11 美商美國禮來大藥廠 抗-N3pGlu類澱粉β肽抗體及其用途
TWI789644B (zh) 2017-04-20 2023-01-11 美商美國禮來大藥廠 抗-N3pGlu類澱粉β肽抗體及其用途
CN107289872A (zh) 2017-06-28 2017-10-24 京东方科技集团股份有限公司 测高装置
KR102905634B1 (ko) 2019-05-31 2025-12-30 일라이 릴리 앤드 캄파니 인간 타우를 표적화하는 화합물 및 방법

Also Published As

Publication number Publication date
TWI843040B (zh) 2024-05-21
AU2022206461A1 (en) 2023-06-29
ZA202306180B (en) 2025-02-26
TW202243690A (zh) 2022-11-16
IL304072A (en) 2023-08-01
MX2023008196A (es) 2023-07-18
KR20260047659A (ko) 2026-04-08
CA3204444A1 (en) 2022-07-14
WO2022150735A1 (en) 2022-07-14
KR20230130695A (ko) 2023-09-12
EP4274611A1 (en) 2023-11-15
CO2023009089A2 (es) 2023-09-29
KR102942744B1 (ko) 2026-03-23
JP7676556B2 (ja) 2025-05-14
CL2023001992A1 (es) 2024-02-02
US20240010713A1 (en) 2024-01-11
JP2025131566A (ja) 2025-09-09
JP2024503025A (ja) 2024-01-24
AU2022206461B2 (en) 2026-02-05
ECSP23051813A (es) 2023-08-31

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