PE20230735A1 - Metodos de tratamiento de trastornos del desarrollo con gaboxadol - Google Patents
Metodos de tratamiento de trastornos del desarrollo con gaboxadolInfo
- Publication number
- PE20230735A1 PE20230735A1 PE2022002752A PE2022002752A PE20230735A1 PE 20230735 A1 PE20230735 A1 PE 20230735A1 PE 2022002752 A PE2022002752 A PE 2022002752A PE 2022002752 A PE2022002752 A PE 2022002752A PE 20230735 A1 PE20230735 A1 PE 20230735A1
- Authority
- PE
- Peru
- Prior art keywords
- gaboxadol
- treatment
- methods
- developmental disorders
- administrable
- Prior art date
Links
- ZXRVKCBLGJOCEE-UHFFFAOYSA-N Gaboxadol Chemical compound C1NCCC2=C1ONC2=O ZXRVKCBLGJOCEE-UHFFFAOYSA-N 0.000 title abstract 4
- 229950004346 gaboxadol Drugs 0.000 title abstract 4
- 208000012239 Developmental disease Diseases 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000001914 Fragile X syndrome Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562193717P | 2015-07-17 | 2015-07-17 | |
| US201562207595P | 2015-08-20 | 2015-08-20 | |
| US201662332567P | 2016-05-06 | 2016-05-06 | |
| US201662346763P | 2016-06-07 | 2016-06-07 | |
| US15/209,862 US20170014393A1 (en) | 2015-07-17 | 2016-07-14 | Methods of treating developmental disorders with gaboxadol |
| PCT/US2016/042238 WO2017015049A1 (en) | 2015-07-17 | 2016-07-14 | Methods of treating developmental disorders with gaboxadol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20230735A1 true PE20230735A1 (es) | 2023-05-03 |
Family
ID=57774846
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2022002752A PE20230735A1 (es) | 2015-07-17 | 2016-07-14 | Metodos de tratamiento de trastornos del desarrollo con gaboxadol |
| PE2018000085A PE20190338A1 (es) | 2015-07-17 | 2016-07-14 | Metodos de tratamiento de trastornos del desarrollo con gaboxadol |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2018000085A PE20190338A1 (es) | 2015-07-17 | 2016-07-14 | Metodos de tratamiento de trastornos del desarrollo con gaboxadol |
Country Status (17)
| Country | Link |
|---|---|
| US (8) | US20170014393A1 (enExample) |
| EP (2) | EP3324961B1 (enExample) |
| JP (3) | JP2018520189A (enExample) |
| KR (2) | KR20180031721A (enExample) |
| CN (2) | CN116531370A (enExample) |
| AU (2) | AU2016295138B2 (enExample) |
| BR (1) | BR112018000933A2 (enExample) |
| CA (1) | CA2992734A1 (enExample) |
| CL (1) | CL2018000142A1 (enExample) |
| CO (1) | CO2018000375A2 (enExample) |
| ES (1) | ES3021189T3 (enExample) |
| HK (1) | HK1250951A1 (enExample) |
| IL (2) | IL256912B2 (enExample) |
| MX (2) | MX391708B (enExample) |
| PE (2) | PE20230735A1 (enExample) |
| TW (2) | TWI819995B (enExample) |
| WO (1) | WO2017015049A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3372229T1 (sl) | 2014-06-06 | 2021-09-30 | Ovid Therapeutics, Inc. | Postopki za povečanje tonične inhibicije in zdravljenje angelman sindroma |
| BR112018000933A2 (pt) | 2015-07-17 | 2018-09-04 | Ovid Therapeutics Inc | métodos de tratamento de um distúrbio de desenvolvimento |
| JP2019524816A (ja) | 2016-08-11 | 2019-09-05 | オービッド・セラピューティクス・インコーポレイテッドＯｖｉｄ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | てんかん性障害の処置のための方法および組成物 |
| AU2017363598A1 (en) * | 2016-11-22 | 2019-05-23 | Ovid Therapeutics Inc. | Methods of treating developmental disorders and/or seizure disorders with flupirtine |
| US10071083B2 (en) | 2017-02-03 | 2018-09-11 | Ovid Therapeutics Inc | Use of gaboxadol in the treatment of tinnitus |
| US20180338959A1 (en) * | 2017-05-24 | 2018-11-29 | Ovid Therapeutics Inc. | Treatment of depressive disorders |
| MX2020001342A (es) | 2017-08-04 | 2020-08-31 | Ovid Therapeutics Inc | Uso de gaboxadol en el tratamiento contra diabetes y afecciones relacionadas. |
| MX2020004974A (es) * | 2017-11-14 | 2020-08-24 | Sk Biopharmaceuticals Co Ltd | Uso del compuesto de carbamato para reducir o tratar trastornos del desarrollo que incluyen sindrome x fragil, sindrome de angelman o sindrome de rett. |
| CN112739353A (zh) * | 2018-06-14 | 2021-04-30 | 奥维德医疗公司 | Mir-92a或mir-145在治疗安格曼综合征中的用途 |
| EP3823619A4 (en) * | 2018-08-22 | 2021-11-17 | Ovid Therapeutics Inc. | USE OF GABOXADOL FOR TREATMENT OF GIOMETAL TRACT DISORDERS AND ASTHMA |
| MX2021003302A (es) | 2018-09-20 | 2021-05-13 | Ovid Therapeutics Inc | Uso de gaboxadol para el tratamiento del sindrome de tourette, los tics y la tartamudez. |
| WO2020106927A1 (en) | 2018-11-21 | 2020-05-28 | Certego Therapeutics | Gaboxadol for reducing risk of suicide and rapid relief of depression |
| WO2020106976A1 (en) * | 2018-11-21 | 2020-05-28 | Certego Therapeutics | Combination of gaboxadol and lithium for the treatment of psychiatric disorders |
| MX2021007224A (es) | 2018-12-17 | 2021-09-23 | Ovid Therapeutics Inc | Uso de gaboxadol para el tratamiento del trastorno del sue?o vigilia que no es de 24 horas. |
| CN114340597B (zh) * | 2019-06-07 | 2025-01-28 | 帕克斯医学有限公司 | 用于治疗中枢神经系统障碍的组合物和方法 |
| AU2020313930A1 (en) * | 2019-07-15 | 2022-02-03 | Ovid Therapeutics Inc. | Pharmaceutical formulations containing gaboxadol for therapeutic treatment |
| JP2023507764A (ja) * | 2019-12-18 | 2023-02-27 | オービッド・セラピューティクス・インコーポレイテッド | １ｐ３６欠失症候群の治療的処置のためのガボキサドール |
| IL298334A (en) | 2020-05-20 | 2023-01-01 | Certego Therapeutics Inc | Ring deuterated gaboxadol and its use for the treatment of psychiatric disorders |
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| WO2014123909A1 (en) | 2013-02-05 | 2014-08-14 | University Of Washington Through Its Center For Commercialization | Positive allosteric modulators of the gaba-a receptor in the treatment of autism |
| SI3372229T1 (sl) * | 2014-06-06 | 2021-09-30 | Ovid Therapeutics, Inc. | Postopki za povečanje tonične inhibicije in zdravljenje angelman sindroma |
| US9802945B2 (en) | 2014-06-12 | 2017-10-31 | Pfizer Limited | Imidazopyridazine derivatives as modulators of the GABAA receptor activity |
| US20170348232A1 (en) | 2016-06-07 | 2017-12-07 | Ovid Therapeutics Inc. | Formulations of gaboxadol for treatment of angelman syndrome, fragile x syndrome and fragile x-associated tremor/ataxia syndrome |
| US9682069B2 (en) | 2015-07-17 | 2017-06-20 | Ovid Therapeutics Inc | Methods of treating Dravet syndrome |
| BR112018000933A2 (pt) * | 2015-07-17 | 2018-09-04 | Ovid Therapeutics Inc | métodos de tratamento de um distúrbio de desenvolvimento |
| US9399034B1 (en) | 2015-08-11 | 2016-07-26 | Ovid Therapeutics Inc | Methods of sedation during critical care treatment |
| PE20181332A1 (es) | 2015-08-11 | 2018-08-20 | Ovid Therapeutics Inc | Metodos de sedacion y formulacion parenteral para uso durante el tratamiento de cuidados criticos |
| US9351968B1 (en) | 2015-09-09 | 2016-05-31 | Ovid Therapeutics Inc | Methods of treating developmental disorders using pipradrol |
| WO2017070680A1 (en) | 2015-10-22 | 2017-04-27 | Cavion Llc | Methods for treating angelman syndrome and related disorders |
| JP2019517469A (ja) | 2016-05-26 | 2019-06-24 | オービッド・セラピューティクス・インコーポレイテッドＯｖｉｄ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | ピプラドロールを用いる行動症候群の治療方法 |
| JP2019524816A (ja) | 2016-08-11 | 2019-09-05 | オービッド・セラピューティクス・インコーポレイテッドＯｖｉｄ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | てんかん性障害の処置のための方法および組成物 |
| AU2017363598A1 (en) | 2016-11-22 | 2019-05-23 | Ovid Therapeutics Inc. | Methods of treating developmental disorders and/or seizure disorders with flupirtine |
| US10071083B2 (en) | 2017-02-03 | 2018-09-11 | Ovid Therapeutics Inc | Use of gaboxadol in the treatment of tinnitus |
-
2016
- 2016-07-14 BR BR112018000933A patent/BR112018000933A2/pt not_active Application Discontinuation
- 2016-07-14 JP JP2018502084A patent/JP2018520189A/ja not_active Withdrawn
- 2016-07-14 PE PE2022002752A patent/PE20230735A1/es unknown
- 2016-07-14 CA CA2992734A patent/CA2992734A1/en active Pending
- 2016-07-14 PE PE2018000085A patent/PE20190338A1/es unknown
- 2016-07-14 IL IL256912A patent/IL256912B2/en unknown
- 2016-07-14 EP EP16828266.3A patent/EP3324961B1/en active Active
- 2016-07-14 IL IL305342A patent/IL305342A/en unknown
- 2016-07-14 MX MX2018000745A patent/MX391708B/es unknown
- 2016-07-14 CN CN202310549878.XA patent/CN116531370A/zh active Pending
- 2016-07-14 KR KR1020187004863A patent/KR20180031721A/ko not_active Ceased
- 2016-07-14 CN CN201680054308.1A patent/CN108024997A/zh active Pending
- 2016-07-14 HK HK18110494.0A patent/HK1250951A1/zh unknown
- 2016-07-14 AU AU2016295138A patent/AU2016295138B2/en active Active
- 2016-07-14 WO PCT/US2016/042238 patent/WO2017015049A1/en not_active Ceased
- 2016-07-14 KR KR1020247036072A patent/KR20240160666A/ko not_active Ceased
- 2016-07-14 US US15/209,862 patent/US20170014393A1/en not_active Abandoned
- 2016-07-14 EP EP25162297.3A patent/EP4541420A3/en active Pending
- 2016-07-14 ES ES16828266T patent/ES3021189T3/es active Active
- 2016-07-15 TW TW105122538A patent/TWI819995B/zh active
- 2016-07-15 TW TW112110413A patent/TW202325293A/zh unknown
-
2017
- 2017-12-13 US US15/840,521 patent/US20180098974A1/en not_active Abandoned
-
2018
- 2018-01-17 MX MX2022004734A patent/MX2022004734A/es unknown
- 2018-01-17 CL CL2018000142A patent/CL2018000142A1/es unknown
- 2018-01-22 CO CONC2018/0000375A patent/CO2018000375A2/es unknown
- 2018-08-02 US US16/053,343 patent/US20180338960A1/en not_active Abandoned
- 2018-12-17 US US16/221,794 patent/US11096929B2/en active Active
-
2019
- 2019-05-01 US US16/400,227 patent/US20190255027A1/en not_active Abandoned
- 2019-06-25 US US16/451,591 patent/US20190321342A1/en not_active Abandoned
-
2020
- 2020-06-25 US US16/911,540 patent/US20210030727A1/en not_active Abandoned
-
2021
- 2021-05-25 JP JP2021087584A patent/JP2021130687A/ja active Pending
- 2021-10-12 AU AU2021250862A patent/AU2021250862B2/en active Active
-
2022
- 2022-11-04 US US17/981,148 patent/US12465597B2/en active Active
-
2023
- 2023-05-16 JP JP2023080696A patent/JP2023103375A/ja active Pending
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