PE20161417A1 - Composiciones de glicoproteinas sialiladas y uso de estas - Google Patents
Composiciones de glicoproteinas sialiladas y uso de estasInfo
- Publication number
- PE20161417A1 PE20161417A1 PE2016001535A PE2016001535A PE20161417A1 PE 20161417 A1 PE20161417 A1 PE 20161417A1 PE 2016001535 A PE2016001535 A PE 2016001535A PE 2016001535 A PE2016001535 A PE 2016001535A PE 20161417 A1 PE20161417 A1 PE 20161417A1
- Authority
- PE
- Peru
- Prior art keywords
- compositions
- mol
- refers
- treatment
- composition
- Prior art date
Links
- 102000003886 Glycoproteins Human genes 0.000 title abstract 3
- 108090000288 Glycoproteins Proteins 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- NBSCHQHZLSJFNQ-QTVWNMPRSA-N D-Mannose-6-phosphate Chemical compound OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O NBSCHQHZLSJFNQ-QTVWNMPRSA-N 0.000 abstract 2
- 101000933465 Homo sapiens Beta-glucuronidase Proteins 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 230000002132 lysosomal effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000025919 mucopolysaccharidosis type 7 Diseases 0.000 abstract 1
- 230000009450 sialylation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2468—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01031—Beta-glucuronidase (3.2.1.31)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461948421P | 2014-03-05 | 2014-03-05 | |
| US201562114313P | 2015-02-10 | 2015-02-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20161417A1 true PE20161417A1 (es) | 2017-01-22 |
Family
ID=54016314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2016001535A PE20161417A1 (es) | 2014-03-05 | 2015-03-05 | Composiciones de glicoproteinas sialiladas y uso de estas |
Country Status (17)
| Country | Link |
|---|---|
| US (8) | US9457067B2 (enExample) |
| EP (1) | EP3113781B1 (enExample) |
| JP (1) | JP6581590B2 (enExample) |
| KR (1) | KR102150481B1 (enExample) |
| CN (1) | CN106102749B (enExample) |
| AU (1) | AU2015227137B2 (enExample) |
| BR (1) | BR112016019893B1 (enExample) |
| CA (1) | CA2940318C (enExample) |
| ES (1) | ES2704923T3 (enExample) |
| IL (1) | IL247550B (enExample) |
| MX (1) | MX368972B (enExample) |
| MY (1) | MY188028A (enExample) |
| PE (1) | PE20161417A1 (enExample) |
| PH (1) | PH12016501658A1 (enExample) |
| RU (1) | RU2689119C2 (enExample) |
| TW (1) | TWI702049B (enExample) |
| WO (1) | WO2015134696A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9457067B2 (en) | 2014-03-05 | 2016-10-04 | Ultragenyx Pharmaceutical Inc. | Sialylated glycoprotein compositions and uses thereof |
| WO2019116259A1 (en) | 2017-12-13 | 2019-06-20 | 3M Innovative Properties Company | Water-reconstitutable culture medium resistant to liquefaction by microorganisms |
| TWI667252B (zh) * | 2018-07-13 | 2019-08-01 | 中原大學 | 阿伐-選擇性唾液酸供體及其於製備唾液酸苷的用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6458574B1 (en) | 1996-09-12 | 2002-10-01 | Transkaryotic Therapies, Inc. | Treatment of a α-galactosidase a deficiency |
| PL376381A1 (en) * | 2002-07-15 | 2005-12-27 | Immunex Corporation | Methods and media for controlling sialylation of proteins produced by mammalian cells |
| US20060104968A1 (en) * | 2003-03-05 | 2006-05-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases |
| KR20060124656A (ko) * | 2003-12-31 | 2006-12-05 | 메르크 파텐트 게엠베하 | 개선된 약물동태를 가지는 Ｆｃ-에리스로포이에틴 융합단백질 |
| EP1818395A1 (en) * | 2006-02-08 | 2007-08-15 | Diatos | Compositions and methods for treating lysosomal storage diseases |
| HRP20150307T1 (hr) * | 2006-09-10 | 2015-04-24 | Glycotope Gmbh | Upotreba ljudskih stanica podrijetlom iz ljudske leukemije za eksprimiranje protutijela |
| US20090041741A1 (en) * | 2007-03-06 | 2009-02-12 | Saint Louis University | Modified enzyme and treatment method |
| CN102482674B (zh) * | 2010-02-08 | 2014-03-26 | 韩国科学技术院 | 制备具有高唾液酸含量的重组糖蛋白的方法 |
| WO2012101671A1 (en) * | 2011-01-25 | 2012-08-02 | Jcr Pharmaceuticals Co., Ltd. | Method for production of human recombinant iduronate 2-sulfatase |
| KR101457514B1 (ko) * | 2011-11-21 | 2014-11-03 | 한국생명공학연구원 | 우렁쉥이(멍게) 유래의 시알산 전이효소 및 이를 이용한 시알화 복합당질 합성 방법 |
| US10138474B2 (en) * | 2012-08-17 | 2018-11-27 | Research Foundation Of The City University Of New York | Scavenger receptor uptake for fabry disease enzyme replacement therapy |
| US9457067B2 (en) | 2014-03-05 | 2016-10-04 | Ultragenyx Pharmaceutical Inc. | Sialylated glycoprotein compositions and uses thereof |
-
2015
- 2015-03-05 US US14/639,171 patent/US9457067B2/en active Active
- 2015-03-05 MY MYPI2016001608A patent/MY188028A/en unknown
- 2015-03-05 MX MX2016011416A patent/MX368972B/es active IP Right Grant
- 2015-03-05 ES ES15758766T patent/ES2704923T3/es active Active
- 2015-03-05 TW TW104107083A patent/TWI702049B/zh active
- 2015-03-05 RU RU2016138790A patent/RU2689119C2/ru active
- 2015-03-05 PE PE2016001535A patent/PE20161417A1/es not_active Application Discontinuation
- 2015-03-05 JP JP2016553591A patent/JP6581590B2/ja active Active
- 2015-03-05 BR BR112016019893-0A patent/BR112016019893B1/pt active IP Right Grant
- 2015-03-05 WO PCT/US2015/018859 patent/WO2015134696A1/en not_active Ceased
- 2015-03-05 CA CA2940318A patent/CA2940318C/en active Active
- 2015-03-05 CN CN201580015886.XA patent/CN106102749B/zh active Active
- 2015-03-05 KR KR1020167026994A patent/KR102150481B1/ko active Active
- 2015-03-05 AU AU2015227137A patent/AU2015227137B2/en active Active
- 2015-03-05 EP EP15758766.8A patent/EP3113781B1/en active Active
- 2015-09-10 US US14/849,745 patent/US9457068B2/en active Active
-
2016
- 2016-08-19 PH PH12016501658A patent/PH12016501658A1/en unknown
- 2016-08-30 US US15/251,701 patent/US9687532B2/en active Active
- 2016-08-30 IL IL247550A patent/IL247550B/en active IP Right Grant
-
2017
- 2017-05-26 US US15/607,257 patent/US9937243B2/en active Active
-
2018
- 2018-04-02 US US15/943,526 patent/US20190054153A1/en not_active Abandoned
-
2020
- 2020-01-09 US US16/738,938 patent/US20200282028A1/en not_active Abandoned
-
2021
- 2021-11-11 US US17/524,628 patent/US20220202915A1/en not_active Abandoned
-
2023
- 2023-12-07 US US18/532,665 patent/US20240245759A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |