PE20151663A1 - Composiciones de principios activos farmaceuticos que contienen monoetil eter dietilenglicol u otros derivados de alquilo - Google Patents
Composiciones de principios activos farmaceuticos que contienen monoetil eter dietilenglicol u otros derivados de alquiloInfo
- Publication number
- PE20151663A1 PE20151663A1 PE2015002110A PE2015002110A PE20151663A1 PE 20151663 A1 PE20151663 A1 PE 20151663A1 PE 2015002110 A PE2015002110 A PE 2015002110A PE 2015002110 A PE2015002110 A PE 2015002110A PE 20151663 A1 PE20151663 A1 PE 20151663A1
- Authority
- PE
- Peru
- Prior art keywords
- diethylene glycol
- monoethyl ether
- alkyl derivatives
- pharmaceutical compositions
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title 1
- ZLPMUYAOHZTBEV-UHFFFAOYSA-N ethoxyethane;2-(2-hydroxyethoxy)ethanol Chemical compound CCOCC.OCCOCCO ZLPMUYAOHZTBEV-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 abstract 2
- 229940075557 diethylene glycol monoethyl ether Drugs 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 230000036576 dermal application Effects 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000007918 intramuscular administration Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000007922 nasal spray Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invencion se relaciona con composiciones farmaceuticas de diversos principios activos farmaceuticos, especialmente principios activos hidrofilos y lipofilos que contienen monoetil eter dietilenglicol u otros derivados de alquilo de los mismos como un vehiculo primario y/o con composiciones farmaceuticas que utilizan monoetil eter dietilenglicol u otros derivados de alquilo de los mismos como un vehiculo primario o como un sistema de disolvente en la preparacion de dichas composiciones farmaceuticas. Las composiciones farmaceuticas de la presente invencion son seguras, no toxicas, exhiben estabilidad fisica mejorada comparado con formulaciones convencionales que contienen dichos principios activos farmaceuticos y son adecuadas para uso como inyectables para administracion intravenosa e intramuscular, asi como tambien para uso como una solucion/liquido preformado para relleno en y preparacion de capsulas, comprimidos, aerosoles nasales, sustancias para hacer gargaras, aplicaciones dermicas, genes, formas de dosificacion oral liquidas topicas y otras formas de dosificacion
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1287MU2013 IN2013MU01287A (es) | 2013-04-02 | 2014-04-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20151663A1 true PE20151663A1 (es) | 2015-12-03 |
Family
ID=51263451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2015002110A PE20151663A1 (es) | 2013-04-02 | 2014-04-02 | Composiciones de principios activos farmaceuticos que contienen monoetil eter dietilenglicol u otros derivados de alquilo |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US9827315B2 (es) |
| JP (1) | JP6272454B2 (es) |
| KR (2) | KR20170110728A (es) |
| CN (1) | CN105392469A (es) |
| AU (1) | AU2014261009B2 (es) |
| BR (1) | BR112015025172A2 (es) |
| CA (1) | CA2908571C (es) |
| HK (1) | HK1222549A1 (es) |
| IN (1) | IN2013MU01287A (es) |
| MA (1) | MA38544A1 (es) |
| MX (1) | MX2015013785A (es) |
| PE (1) | PE20151663A1 (es) |
| PH (1) | PH12015502290B1 (es) |
| SA (1) | SA515361262B1 (es) |
| SG (1) | SG11201508006SA (es) |
| UA (1) | UA119324C2 (es) |
| WO (1) | WO2014178065A1 (es) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120225918A1 (en) | 2011-03-03 | 2012-09-06 | Voom, Llc | Compositions and Methods for Non-Surgical Treatment of Ptosis |
| US9713621B2 (en) * | 2012-01-19 | 2017-07-25 | Edward Lichten | Treatment of endometriosis |
| JP6360039B2 (ja) | 2012-05-03 | 2018-07-18 | カラ ファーマシューティカルズ インコーポレイテッド | 複数の被覆された粒子を含む組成物、医薬組成物、医薬製剤、及び当該粒子の形成方法 |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| EP3808339B1 (en) | 2012-05-03 | 2025-11-12 | Alcon Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
| US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| US9125805B2 (en) | 2012-06-27 | 2015-09-08 | Xeris Pharmaceuticals, Inc. | Stable formulations for parenteral injection of small molecule drugs |
| US8568747B1 (en) | 2012-10-05 | 2013-10-29 | Silvergate Pharmaceuticals, Inc. | Enalapril compositions |
| CN104546775B (zh) * | 2015-02-03 | 2017-08-25 | 山东新时代药业有限公司 | 一种阿托伐他汀钙片剂 |
| US20170042806A1 (en) | 2015-04-29 | 2017-02-16 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| US10537520B2 (en) | 2015-06-30 | 2020-01-21 | Leiutis Pharmaceuticals Pvt. Ltd. | Stable liquid formulations of melphalan |
| JP2018530597A (ja) * | 2015-10-13 | 2018-10-18 | テミス メディケア リミティド | フルベストラント組成物 |
| KR101634382B1 (ko) * | 2015-10-20 | 2016-06-28 | 미래제약 주식회사 | 타다라필 경구용 액제 |
| US9463183B1 (en) | 2015-10-30 | 2016-10-11 | Silvergate Pharmaceuticals, Inc. | Lisinopril formulations |
| US20180325813A1 (en) * | 2015-11-07 | 2018-11-15 | Ftf Pharma Private Limited | Oral solution of ace inhibitors |
| EP3407875A4 (en) * | 2016-01-29 | 2019-09-04 | Cuda Anesthetics, LLC | AQUEOUS PHARMACEUTICAL FORMULATION WITH PROPOFOL |
| US9669008B1 (en) | 2016-03-18 | 2017-06-06 | Silvergate Pharmaceuticals, Inc. | Enalapril formulations |
| BR112018070960A2 (pt) | 2016-04-13 | 2019-01-29 | Nortic Holdings Inc. | formulação parenteral de nimodipina estável |
| US10092553B2 (en) | 2016-04-13 | 2018-10-09 | Nortic Holdings Inc. | Stable nimodipine parenteral formulation |
| EP3452033A4 (en) * | 2016-05-06 | 2020-02-12 | Harrow IP, LLC | PHARMACEUTICAL OPHTHALMIC COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| FI3474822T3 (fi) | 2016-06-28 | 2025-08-15 | Emergent Biodefense Operations Lansing Llc | Brinsidofoviirin formulaatioita |
| CA3036356A1 (en) | 2016-09-09 | 2018-03-15 | Cutispharma, Inc. | Suspensions and diluents for metronidazole and baclofen |
| FR3057775B1 (fr) * | 2016-10-26 | 2018-11-02 | Crossject | Solution pharmaceutique d’hydrocortisone pour dispositif d’injection |
| BE1024559B1 (nl) * | 2017-02-21 | 2018-04-05 | Purna Pharmaceuticals Nv | Werkwijze voor het maken van een verstuifbare emulsie omvattende een corticosteroïde, een aminoglycoside en een zuur |
| CN108721209A (zh) * | 2017-04-20 | 2018-11-02 | 广东东阳光药业有限公司 | 一种兽用阿奇霉素注射剂 |
| US11020403B2 (en) | 2017-06-02 | 2021-06-01 | Xeris Pharmaceuticals, Inc. | Precipitation resistant small molecule drug formulations |
| US9895359B1 (en) | 2017-06-07 | 2018-02-20 | Arcutis, Inc. | Inhibition of crystal growth of roflumilast |
| US12042487B2 (en) | 2018-11-16 | 2024-07-23 | Arcutis Biotherapeutics, Inc. | Method for reducing side effects from administration of phosphodiesterase-4 inhibitors |
| US20200155524A1 (en) | 2018-11-16 | 2020-05-21 | Arcutis, Inc. | Method for reducing side effects from administration of phosphodiesterase-4 inhibitors |
| US11129818B2 (en) | 2017-06-07 | 2021-09-28 | Arcutis Biotherapeutics, Inc. | Topical roflumilast formulation having improved delivery and plasma half life |
| US20210161870A1 (en) | 2017-06-07 | 2021-06-03 | Arcutis Biotherapeutics, Inc. | Roflumilast formulations with an improved pharmacokinetic profile |
| US12011437B1 (en) | 2017-06-07 | 2024-06-18 | Arcutis Biotherapeutics, Inc. | Roflumilast formulations with an improved pharmacokinetic profile |
| PT3664800T (pt) * | 2017-08-09 | 2024-08-14 | Dechra Veterinary Products Llc | Formulações terapêuticas que compreendem inibidor da cox-2 e utilizações das mesmas |
| US11534493B2 (en) * | 2017-09-22 | 2022-12-27 | Arcutis Biotherapeutics, Inc. | Pharmaceutical compositions of roflumilast in aqueous blends of water-miscible, pharmaceutically acceptable solvents |
| JP7268026B2 (ja) | 2017-12-05 | 2023-05-02 | サノビオン ファーマシューティカルズ インク | 非ラセミ混合物およびその使用 |
| US10377708B2 (en) | 2017-12-05 | 2019-08-13 | Sunovion Pharmaceuticals Inc. | Crystal forms and production methods thereof |
| WO2019182745A1 (en) | 2018-03-19 | 2019-09-26 | Bryn Pharma, LLC | Epinephrine spray formulations |
| CN110314158A (zh) * | 2018-03-22 | 2019-10-11 | 深圳澳美制药技术开发有限公司 | 噻康唑组合物及其制备方法 |
| US10799138B2 (en) | 2018-04-05 | 2020-10-13 | University Of Maryland, Baltimore | Method of administering sotalol IV/switch |
| CN119097625A (zh) | 2018-06-04 | 2024-12-10 | 阿尔库缇斯生物疗法股份有限公司 | 改善罗氟司特皮肤渗透滞后时间的方法和制剂 |
| US11696902B2 (en) | 2018-08-14 | 2023-07-11 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| US11610660B1 (en) | 2021-08-20 | 2023-03-21 | AltaThera Pharmaceuticals LLC | Antiarrhythmic drug dosing methods, medical devices, and systems |
| US11344518B2 (en) | 2018-08-14 | 2022-05-31 | AltaThera Pharmaceuticals LLC | Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame |
| US12396970B2 (en) | 2021-08-20 | 2025-08-26 | AltaThera Pharmaceuticals LLC | Anti-arrhythmic compositions and methods |
| US10512620B1 (en) | 2018-08-14 | 2019-12-24 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| CN109364021A (zh) * | 2018-10-26 | 2019-02-22 | 山西普德药业有限公司 | 一种注射用长春西汀 |
| US10799481B1 (en) | 2019-05-06 | 2020-10-13 | Rvl Pharmaceuticals, Inc. | Compositions and methods for treating ocular disorders |
| JP2022535893A (ja) | 2019-06-04 | 2022-08-10 | サノビオン ファーマシューティカルズ インク | 放出調節製剤およびその使用 |
| KR20220020911A (ko) | 2019-06-14 | 2022-02-21 | 프로펠라 쎄라퓨틱스, 인크. | 국소 아시클로버 제형 및 이의 용도 |
| CN116474218A (zh) * | 2019-06-28 | 2023-07-25 | 四川普锐特药业有限公司 | 保持给药均一度的药物流体分配器及右美托咪定鼻喷器 |
| US11135208B2 (en) | 2019-08-12 | 2021-10-05 | American Regent, Inc. | 1,4-dihydropyridine compositions, methods of making and use |
| EP4233854A3 (en) * | 2019-11-01 | 2024-01-17 | Piedmont Animal Health Inc. | Therapeutic formulations and uses thereof |
| EP4076442A4 (en) * | 2019-12-16 | 2024-01-03 | Themis Medicare Limited | Pharmaceutical composition of cyclooxygenase - 2 inhibitors |
| CN111632029B (zh) * | 2020-06-28 | 2021-05-07 | 江苏吴中医药集团有限公司 | 一种美索巴莫注射液及其制备方法 |
| KR20230104131A (ko) * | 2020-09-21 | 2023-07-07 | 안타레스 팔마, 인코퍼레이티드 | 히드로코티손 인산나트륨 및 모노티오글리세롤의 수성 약학 제형 |
| ES3033851T3 (en) | 2020-12-04 | 2025-08-08 | Arcutis Biotherapeutics Inc | Topical roflumilast formulation having antifungal properties |
| CN112315905B (zh) * | 2020-12-07 | 2021-11-30 | 安徽海洋药业有限公司 | 一种蒿甲醚注射液及其制备方法 |
| CN112370422B (zh) * | 2020-12-09 | 2023-03-03 | 南京联智医药科技有限公司 | 取代的β-环糊精稳定的盐酸屈他维林注射液及其制备方法 |
| US11452690B1 (en) | 2021-01-27 | 2022-09-27 | ECI Pharmaceuticals, LLC | Oral liquid compositions comprising amlodipine besylate and methods of using the same |
| CN113004301B (zh) * | 2021-03-11 | 2022-02-18 | 广西师范大学 | 一种青蒿琥酯基-二苯基脲衍生物ars-dpu及其制备方法与应用 |
| CN113069527B (zh) * | 2021-04-20 | 2022-03-18 | 北京华睿鼎信科技有限公司 | 一种具有解酒保肝功能的组合物及其制备方法 |
| CN115252801B (zh) * | 2021-04-29 | 2025-07-08 | 苏州裕泰医药科技有限公司 | 多西他赛-油酸甘油三酯前药及脂质制剂的制备 |
| CN115702936A (zh) * | 2021-08-13 | 2023-02-17 | 杭州中美华东制药有限公司 | 一种芦可替尼组合物及其用途 |
| FR3128874B1 (fr) * | 2021-11-09 | 2025-04-18 | Crossject | Solution pharmaceutique d’hydrocortisone pour dispositif d’injection |
| CA3242322A1 (en) | 2021-12-28 | 2023-07-06 | Arcutis Biotherapeutics, Inc. | Topical roflumilast aerosol foams |
| EP4233837A1 (en) * | 2022-02-24 | 2023-08-30 | CellAct Pharma GmbH | Solid and oral etoposide toniribate compositions |
| CN119300828A (zh) | 2022-05-16 | 2025-01-10 | 美国阿卡斯蒂制药股份有限公司 | 尼莫地平肠胃外给药 |
| KR20250057103A (ko) | 2022-09-15 | 2025-04-28 | 아큐티스 바이오테라퓨틱스, 인크. | 로플루밀라스트 및 많은 양의 약물을 용해시킬 수 있는 용매의 약학 조성물 |
| KR20240105964A (ko) * | 2022-12-29 | 2024-07-08 | 주식회사 삼양홀딩스 | 약동학적 특성이 우수한 풀베스트란트의 약학 조성물 및 그 제조 방법 |
| WO2024163030A1 (en) * | 2023-02-03 | 2024-08-08 | Brillian Pharma Inc. | Amlodipine freeze-dried compositions and uses thereof |
| WO2025041069A1 (en) * | 2023-08-23 | 2025-02-27 | Reena Patel | Stabilized pharmaceutical compositions of proton pump inhibitors |
| US20250114388A1 (en) * | 2023-10-09 | 2025-04-10 | Dr. Anti Fungus, LLC | Active pharmaceutical ingredient compositions and preparation and uses thereof |
| WO2025078989A1 (en) * | 2023-10-11 | 2025-04-17 | Reena Patel | Stabilized pharmaceutical compositions |
| KR20250142811A (ko) * | 2024-03-22 | 2025-09-30 | 주식회사 에아스텍 | 노르에티스테론 에난테이트 화합물의 암의 예방 또는 치료 용도 |
| KR20250176964A (ko) * | 2024-06-13 | 2025-12-22 | 주식회사 종근당 | 타다라필 또는 이의 약학적으로 허용가능한 염을 포함하는 주사용 조성물 |
| CN119269809B (zh) * | 2024-11-27 | 2025-09-12 | 南京颐兰贝生物科技有限责任公司 | 一种用于定量检测雌二醇测定试剂盒 |
| CN119499177A (zh) * | 2024-11-28 | 2025-02-25 | 江苏知原药业股份有限公司 | 一种含有非挥发性溶剂的过氧化苯甲酰外用组合物 |
| CN121287617A (zh) * | 2025-12-10 | 2026-01-09 | 博济医药科技股份有限公司 | 一种氟康唑滴耳液及其制备方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030157187A1 (en) * | 1996-12-02 | 2003-08-21 | Angiotech Pharmaceuticals, Inc. | Compositions and methods for treating or preventing inflammatory diseases |
| FR2756736B1 (fr) * | 1996-12-05 | 1999-03-05 | Sanofi Sa | Compositions pharmaceutiques contenant des derives de n-sulfonyl indoline |
| US20030104048A1 (en) * | 1999-02-26 | 2003-06-05 | Lipocine, Inc. | Pharmaceutical dosage forms for highly hydrophilic materials |
| KR100382347B1 (ko) * | 2000-10-30 | 2003-05-01 | 에스케이케미칼주식회사 | 시트상 자기발열체 및 이의 제조방법 |
| IL142037A0 (en) * | 2001-03-15 | 2002-03-10 | Agis Ind 1983 Ltd | Pharmaceutical compositions containing a non-steroidal anti-inflammatory drug |
| US6551615B1 (en) | 2001-10-18 | 2003-04-22 | M/S. Strides Arcolab Limited | Dexibuprofen-containing soft gelatin capsules and process for preparing the same |
| AU2002357012A1 (en) * | 2001-11-27 | 2003-06-10 | Transform Pharmaceuticals, Inc. | Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof |
| EP1501925A4 (en) * | 2002-05-17 | 2006-10-25 | New Horizons Diagnostics Corp | IDENTIFICATION OF A LYTIC ENZYME ASSOCIATED WITH A PHAGE TO DETECT AND ELIMINATE RAPIDLY AND SPECIFICALLY BACILLUS ANTHRACIS |
| US6967194B1 (en) * | 2002-09-18 | 2005-11-22 | Susan Matsuo | Bio-identical hormones and method of use |
| JP4542743B2 (ja) * | 2002-12-26 | 2010-09-15 | Kdl株式会社 | ピリドン誘導体の溶液状医薬組成物 |
| ATE411046T1 (de) * | 2004-12-21 | 2008-10-15 | Intervet Int Bv | Injizierbare veterinärmedizinische zusammensetzung enthaltend florfenicol |
| JP2009519343A (ja) * | 2005-12-13 | 2009-05-14 | ハルクネスス プハルマセウティカルス,インコーポレイテッド | エンテロスタチンの非吸湿性組成物 |
| US20110020440A1 (en) * | 2007-11-19 | 2011-01-27 | Cadila Pharmaceuticals Limited | Stable solutions of sparingly soluble actives |
| US8128913B1 (en) * | 2007-12-06 | 2012-03-06 | Skinvisible Pharmaceuticals, Inc. | Sunscreen composition with enhanced UV-A absorber stability and methods |
| HUP0700828A2 (en) * | 2007-12-20 | 2010-01-28 | Richter Gedeon Nyrt | Transdermal pharmaceutical compositions containing tolperisone alone and in combination |
| US20090258069A1 (en) * | 2008-04-15 | 2009-10-15 | John Burnier | Delivery of LFA-1 antagonists to the gastrointestinal system |
| KR101096429B1 (ko) * | 2008-07-18 | 2011-12-20 | 한국유나이티드제약 주식회사 | 안정성이 향상된 아세클로페낙의 경구용 연질캅셀제 |
| US20100215726A1 (en) * | 2009-02-25 | 2010-08-26 | Peter Thomas Roth | Compositions for Diminishing the Appearance of Wrinkles |
| US9744142B2 (en) * | 2009-05-05 | 2017-08-29 | Board Of Regents, The University Of Texas Systems | Formulations of volatile anesthetics and methods of use for reducing inflammation |
| EP3141246A1 (en) * | 2009-08-31 | 2017-03-15 | Dr. Reddy's Laboratories Ltd. | Topical formulations comprising a steroid |
| US9737478B2 (en) * | 2009-09-28 | 2017-08-22 | National Institutes of Health (NIH), U.S. Dept. of Health and Human Services (DHHS), The United States of America NIH Division of Extramural Inventions and Technology Resources (DEITR) | Treatment of malaria |
| EP2504034A4 (en) * | 2009-11-27 | 2014-03-19 | Nuvo Res Inc | Topical ibuprofen formulations |
| EP2575813A1 (en) * | 2010-05-28 | 2013-04-10 | Nuvo Research Inc. | Topical etoricoxib formulation |
| US8747818B1 (en) * | 2011-02-07 | 2014-06-10 | Dennis Gross | Self-tanning compositions |
| HUE046750T2 (hu) * | 2011-05-03 | 2020-03-30 | Aponia Laboratories Inc | Az ibuprofen transzdermális készítményei és azok felhasználási módjai |
| IN2014DN11063A (es) * | 2012-06-27 | 2015-09-25 | Medincell |
-
2014
- 2014-02-04 UA UAA201510577A patent/UA119324C2/uk unknown
- 2014-04-02 AU AU2014261009A patent/AU2014261009B2/en not_active Ceased
- 2014-04-02 KR KR1020177026610A patent/KR20170110728A/ko not_active Withdrawn
- 2014-04-02 IN IN1287MU2013 patent/IN2013MU01287A/en unknown
- 2014-04-02 MA MA38544A patent/MA38544A1/fr unknown
- 2014-04-02 BR BR112015025172A patent/BR112015025172A2/pt not_active IP Right Cessation
- 2014-04-02 WO PCT/IN2014/000207 patent/WO2014178065A1/en not_active Ceased
- 2014-04-02 US US14/242,973 patent/US9827315B2/en not_active Expired - Fee Related
- 2014-04-02 MX MX2015013785A patent/MX2015013785A/es unknown
- 2014-04-02 PE PE2015002110A patent/PE20151663A1/es not_active Application Discontinuation
- 2014-04-02 KR KR1020157031380A patent/KR101875263B1/ko not_active Expired - Fee Related
- 2014-04-02 SG SG11201508006SA patent/SG11201508006SA/en unknown
- 2014-04-02 JP JP2016505930A patent/JP6272454B2/ja not_active Expired - Fee Related
- 2014-04-02 CN CN201480024878.7A patent/CN105392469A/zh active Pending
- 2014-04-02 HK HK16110701.1A patent/HK1222549A1/zh unknown
- 2014-04-02 CA CA2908571A patent/CA2908571C/en not_active Expired - Fee Related
-
2015
- 2015-10-02 PH PH12015502290A patent/PH12015502290B1/en unknown
- 2015-10-04 SA SA515361262A patent/SA515361262B1/ar unknown
-
2017
- 2017-11-02 US US15/801,390 patent/US10940205B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016515609A (ja) | 2016-05-30 |
| SA515361262B1 (ar) | 2018-08-18 |
| AU2014261009B2 (en) | 2017-05-04 |
| PH12015502290A1 (en) | 2016-02-01 |
| HK1222549A1 (zh) | 2017-07-07 |
| KR20150126067A (ko) | 2015-11-10 |
| AU2014261009A1 (en) | 2015-10-29 |
| PH12015502290B1 (en) | 2016-02-01 |
| US20140296191A1 (en) | 2014-10-02 |
| CA2908571C (en) | 2018-11-06 |
| KR101875263B1 (ko) | 2018-07-05 |
| CA2908571A1 (en) | 2014-11-06 |
| UA119324C2 (uk) | 2019-06-10 |
| SG11201508006SA (en) | 2015-10-29 |
| MX2015013785A (es) | 2016-08-19 |
| BR112015025172A2 (pt) | 2017-07-18 |
| IN2013MU01287A (es) | 2015-05-29 |
| MA38544A1 (fr) | 2017-03-31 |
| KR20170110728A (ko) | 2017-10-11 |
| WO2014178065A1 (en) | 2014-11-06 |
| US10940205B2 (en) | 2021-03-09 |
| US20180071390A1 (en) | 2018-03-15 |
| US9827315B2 (en) | 2017-11-28 |
| CN105392469A (zh) | 2016-03-09 |
| JP6272454B2 (ja) | 2018-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE20151663A1 (es) | Composiciones de principios activos farmaceuticos que contienen monoetil eter dietilenglicol u otros derivados de alquilo | |
| MX2018003096A (es) | Composicion farmaceutica que contiene farmaco anionico, y metodo de preparacion para la misma. | |
| NZ709958A (en) | Enhanced stability of novel liquid compositions | |
| ECSP088403A (es) | Formulacion farmaceutica de absorción oral y su método de administracion | |
| CR20140365A (es) | Compuestos de carbamato y preparación y uso de los mismos | |
| PE20080765A1 (es) | Formas de dosificacion farmaceutica | |
| CO2019012814A2 (es) | Composición farmacéutica líquida estable | |
| DOP2015000005A (es) | Derivados de estra 1,3,5(10), 16 tetraeno 3 sustituidos, métodos para su preparación, preparaciones farmacéuticas que los contienen, así como su uso para la preparación de medicamentos | |
| DOP2016000007A (es) | Pirazolpiridinas sustituidas | |
| BR112016008994A2 (pt) | Compostos de pirido[2,3-d]pirimidin-4-ona como inibidores de tanquirase | |
| PE20160850A1 (es) | Sistema multiparticulado para administrar drogas | |
| BR112015027436A8 (pt) | composição tópica e veículo para administração de ingredientes farmaceuticamente ou cosmeticamente ativos | |
| MX2015010486A (es) | Composicion masticable para administracion oral y proceso para preparar la misma. | |
| MX369778B (es) | Potenciadores de solubilidad del agua a base de glucogeno. | |
| MX2016014256A (es) | Formulaciones y metodos para el suministro vaginal de antiprogestinas. | |
| RU2015137043A (ru) | Жидкие ментол-содержащие композиции | |
| PE20130782A1 (es) | Composiciones farmaceuticas que consisten de paracetamol y el proceso para la preparacion del mismo | |
| MX2021000769A (es) | Composicion farmaceutica que contiene clomipramina y metodo de preparacion de la misma. | |
| BR112015014180A8 (pt) | composições de gel | |
| UA107631C2 (uk) | Фармацевтична композиція лікарського засобу седативної і спазмолітичної дії у формі м'яких желатинових капсул (варіанти) | |
| MX2014013083A (es) | Composicion farmaceutica inyectable de dexketoprofeno y tramadol. | |
| MX2015008330A (es) | Composiciones farmaceuticas veterinarias novedosas y un metodo para la produccion de las mismas. | |
| CR20150411A (es) | Composiciones farmacéuticas que contienen dexketoprofeno y tramadol | |
| UY35329A (es) | Composición farmacéutica para administración oral que comprende fexofenadina y proceso para preparar la misma. | |
| MX2015011099A (es) | Composiciones farmaceuticas de donepezilo que tienen un perfil de disolución in vitro o parámetros farmacocinéticos específicos. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |