PE20151663A1 - Composiciones de principios activos farmaceuticos que contienen monoetil eter dietilenglicol u otros derivados de alquilo - Google Patents
Composiciones de principios activos farmaceuticos que contienen monoetil eter dietilenglicol u otros derivados de alquiloInfo
- Publication number
- PE20151663A1 PE20151663A1 PE2015002110A PE2015002110A PE20151663A1 PE 20151663 A1 PE20151663 A1 PE 20151663A1 PE 2015002110 A PE2015002110 A PE 2015002110A PE 2015002110 A PE2015002110 A PE 2015002110A PE 20151663 A1 PE20151663 A1 PE 20151663A1
- Authority
- PE
- Peru
- Prior art keywords
- diethylene glycol
- monoethyl ether
- alkyl derivatives
- pharmaceutical compositions
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title 1
- ZLPMUYAOHZTBEV-UHFFFAOYSA-N ethoxyethane;2-(2-hydroxyethoxy)ethanol Chemical compound CCOCC.OCCOCCO ZLPMUYAOHZTBEV-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 abstract 2
- 229940075557 diethylene glycol monoethyl ether Drugs 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 230000036576 dermal application Effects 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000007918 intramuscular administration Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000007922 nasal spray Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invencion se relaciona con composiciones farmaceuticas de diversos principios activos farmaceuticos, especialmente principios activos hidrofilos y lipofilos que contienen monoetil eter dietilenglicol u otros derivados de alquilo de los mismos como un vehiculo primario y/o con composiciones farmaceuticas que utilizan monoetil eter dietilenglicol u otros derivados de alquilo de los mismos como un vehiculo primario o como un sistema de disolvente en la preparacion de dichas composiciones farmaceuticas. Las composiciones farmaceuticas de la presente invencion son seguras, no toxicas, exhiben estabilidad fisica mejorada comparado con formulaciones convencionales que contienen dichos principios activos farmaceuticos y son adecuadas para uso como inyectables para administracion intravenosa e intramuscular, asi como tambien para uso como una solucion/liquido preformado para relleno en y preparacion de capsulas, comprimidos, aerosoles nasales, sustancias para hacer gargaras, aplicaciones dermicas, genes, formas de dosificacion oral liquidas topicas y otras formas de dosificacion
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1287MU2013 IN2013MU01287A (es) | 2013-04-02 | 2014-04-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20151663A1 true PE20151663A1 (es) | 2015-12-03 |
Family
ID=51263451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2015002110A PE20151663A1 (es) | 2013-04-02 | 2014-04-02 | Composiciones de principios activos farmaceuticos que contienen monoetil eter dietilenglicol u otros derivados de alquilo |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US9827315B2 (es) |
| JP (1) | JP6272454B2 (es) |
| KR (2) | KR101875263B1 (es) |
| CN (1) | CN105392469A (es) |
| AU (1) | AU2014261009B2 (es) |
| BR (1) | BR112015025172A2 (es) |
| CA (1) | CA2908571C (es) |
| HK (1) | HK1222549A1 (es) |
| IN (1) | IN2013MU01287A (es) |
| MA (1) | MA38544A1 (es) |
| MX (1) | MX2015013785A (es) |
| PE (1) | PE20151663A1 (es) |
| PH (1) | PH12015502290A1 (es) |
| SA (1) | SA515361262B1 (es) |
| SG (1) | SG11201508006SA (es) |
| UA (1) | UA119324C2 (es) |
| WO (1) | WO2014178065A1 (es) |
Families Citing this family (82)
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| ES3055223T3 (en) | 2012-05-03 | 2026-02-10 | Alcon Inc | Pharmaceutical nanoparticles showing improved mucosal transport |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| JP6360039B2 (ja) | 2012-05-03 | 2018-07-18 | カラ ファーマシューティカルズ インコーポレイテッド | 複数の被覆された粒子を含む組成物、医薬組成物、医薬製剤、及び当該粒子の形成方法 |
| US9125805B2 (en) | 2012-06-27 | 2015-09-08 | Xeris Pharmaceuticals, Inc. | Stable formulations for parenteral injection of small molecule drugs |
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| WO2025041069A1 (en) * | 2023-08-23 | 2025-02-27 | Reena Patel | Stabilized pharmaceutical compositions of proton pump inhibitors |
| WO2025080638A1 (en) * | 2023-10-09 | 2025-04-17 | Dr. Anti Fungus, LLC | Active pharmaceutical ingredient compositions and preparation and uses thereof |
| WO2025078989A1 (en) * | 2023-10-11 | 2025-04-17 | Reena Patel | Stabilized pharmaceutical compositions |
| CN117442615A (zh) * | 2023-11-23 | 2024-01-26 | 陕西丽彩药业有限公司 | 一种h2受体拮抗剂药物组合物及其制备方法 |
| WO2025198399A1 (ko) * | 2024-03-22 | 2025-09-25 | 주식회사 에아스텍 | 노르에티스테론 에난테이트 화합물의 암의 예방 또는 치료 용도 |
| KR20250176964A (ko) * | 2024-06-13 | 2025-12-22 | 주식회사 종근당 | 타다라필 또는 이의 약학적으로 허용가능한 염을 포함하는 주사용 조성물 |
| CN118743693A (zh) * | 2024-06-25 | 2024-10-08 | 杭州成邦医药科技有限公司 | 一种雷美替胺透皮贴剂及其制备方法 |
| CN119269809B (zh) * | 2024-11-27 | 2025-09-12 | 南京颐兰贝生物科技有限责任公司 | 一种用于定量检测雌二醇测定试剂盒 |
| CN119499177A (zh) * | 2024-11-28 | 2025-02-25 | 江苏知原药业股份有限公司 | 一种含有非挥发性溶剂的过氧化苯甲酰外用组合物 |
| CN121287617B (zh) * | 2025-12-10 | 2026-04-17 | 博济医药科技股份有限公司 | 一种氟康唑滴耳液及其制备方法 |
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| US20030157187A1 (en) * | 1996-12-02 | 2003-08-21 | Angiotech Pharmaceuticals, Inc. | Compositions and methods for treating or preventing inflammatory diseases |
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| IL142037A0 (en) * | 2001-03-15 | 2002-03-10 | Agis Ind 1983 Ltd | Pharmaceutical compositions containing a non-steroidal anti-inflammatory drug |
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| US20100215726A1 (en) * | 2009-02-25 | 2010-08-26 | Peter Thomas Roth | Compositions for Diminishing the Appearance of Wrinkles |
| CN109394689A (zh) * | 2009-05-05 | 2019-03-01 | 德州大学系统董事会 | 挥发性麻醉剂的新型制剂及其用于减轻炎症的使用方法 |
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| US9737478B2 (en) * | 2009-09-28 | 2017-08-22 | National Institutes of Health (NIH), U.S. Dept. of Health and Human Services (DHHS), The United States of America NIH Division of Extramural Inventions and Technology Resources (DEITR) | Treatment of malaria |
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2014
- 2014-02-04 UA UAA201510577A patent/UA119324C2/uk unknown
- 2014-04-02 JP JP2016505930A patent/JP6272454B2/ja not_active Expired - Fee Related
- 2014-04-02 HK HK16110701.1A patent/HK1222549A1/zh unknown
- 2014-04-02 KR KR1020157031380A patent/KR101875263B1/ko not_active Expired - Fee Related
- 2014-04-02 SG SG11201508006SA patent/SG11201508006SA/en unknown
- 2014-04-02 MA MA38544A patent/MA38544A1/fr unknown
- 2014-04-02 CN CN201480024878.7A patent/CN105392469A/zh active Pending
- 2014-04-02 MX MX2015013785A patent/MX2015013785A/es unknown
- 2014-04-02 IN IN1287MU2013 patent/IN2013MU01287A/en unknown
- 2014-04-02 KR KR1020177026610A patent/KR20170110728A/ko not_active Withdrawn
- 2014-04-02 WO PCT/IN2014/000207 patent/WO2014178065A1/en not_active Ceased
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- 2014-04-02 BR BR112015025172A patent/BR112015025172A2/pt not_active IP Right Cessation
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2015
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| PH12015502290B1 (en) | 2016-02-01 |
| AU2014261009A1 (en) | 2015-10-29 |
| IN2013MU01287A (es) | 2015-05-29 |
| CA2908571C (en) | 2018-11-06 |
| KR101875263B1 (ko) | 2018-07-05 |
| CA2908571A1 (en) | 2014-11-06 |
| HK1222549A1 (zh) | 2017-07-07 |
| SG11201508006SA (en) | 2015-10-29 |
| KR20150126067A (ko) | 2015-11-10 |
| US20140296191A1 (en) | 2014-10-02 |
| CN105392469A (zh) | 2016-03-09 |
| AU2014261009B2 (en) | 2017-05-04 |
| US9827315B2 (en) | 2017-11-28 |
| KR20170110728A (ko) | 2017-10-11 |
| MX2015013785A (es) | 2016-08-19 |
| JP6272454B2 (ja) | 2018-01-31 |
| JP2016515609A (ja) | 2016-05-30 |
| US10940205B2 (en) | 2021-03-09 |
| PH12015502290A1 (en) | 2016-02-01 |
| WO2014178065A1 (en) | 2014-11-06 |
| UA119324C2 (uk) | 2019-06-10 |
| BR112015025172A2 (pt) | 2017-07-18 |
| US20180071390A1 (en) | 2018-03-15 |
| SA515361262B1 (ar) | 2018-08-18 |
| MA38544A1 (fr) | 2017-03-31 |
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