PE20150603A1 - Metodo para producir iduronato-2-sulfatasa recombinante - Google Patents
Metodo para producir iduronato-2-sulfatasa recombinanteInfo
- Publication number
- PE20150603A1 PE20150603A1 PE2014002540A PE2014002540A PE20150603A1 PE 20150603 A1 PE20150603 A1 PE 20150603A1 PE 2014002540 A PE2014002540 A PE 2014002540A PE 2014002540 A PE2014002540 A PE 2014002540A PE 20150603 A1 PE20150603 A1 PE 20150603A1
- Authority
- PE
- Peru
- Prior art keywords
- sulfatase
- recombinant
- produce recombinant
- protein
- recombinant iduronate
- Prior art date
Links
- 102100029199 Iduronate 2-sulfatase Human genes 0.000 title abstract 5
- 101710096421 Iduronate 2-sulfatase Proteins 0.000 title abstract 5
- 210000004962 mammalian cell Anatomy 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- UGJBHEZMOKVTIM-UHFFFAOYSA-N N-formylglycine Chemical compound OC(=O)CNC=O UGJBHEZMOKVTIM-UHFFFAOYSA-N 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y108/00—Oxidoreductases acting on sulfur groups as donors (1.8)
- C12Y108/99—Oxidoreductases acting on sulfur groups as donors (1.8) with other acceptors (1.8.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/06—Sulfuric ester hydrolases (3.1.6)
- C12Y301/06013—Iduronate-2-sulfatase (3.1.6.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/40—Nucleotides, nucleosides or bases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/44—Thiols, e.g. mercaptoethanol
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2523/00—Culture process characterised by temperature
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261666712P | 2012-06-29 | 2012-06-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20150603A1 true PE20150603A1 (es) | 2015-05-27 |
Family
ID=49778402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2014002540A PE20150603A1 (es) | 2012-06-29 | 2013-06-28 | Metodo para producir iduronato-2-sulfatasa recombinante |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20140004097A1 (https=) |
| EP (1) | EP2867367A4 (https=) |
| JP (1) | JP2015523074A (https=) |
| KR (1) | KR20150037908A (https=) |
| CN (1) | CN104583414A (https=) |
| AU (1) | AU2013282417A1 (https=) |
| BR (1) | BR112014032544A2 (https=) |
| CA (1) | CA2877492A1 (https=) |
| CL (1) | CL2014003569A1 (https=) |
| CO (1) | CO7240395A2 (https=) |
| CR (1) | CR20140587A (https=) |
| DO (1) | DOP2014000297A (https=) |
| EA (1) | EA201492185A1 (https=) |
| HK (2) | HK1209790A1 (https=) |
| IL (1) | IL236324A0 (https=) |
| IN (1) | IN2014DN11272A (https=) |
| MX (1) | MX2015000188A (https=) |
| PE (1) | PE20150603A1 (https=) |
| PH (1) | PH12014502870A1 (https=) |
| SG (1) | SG11201408755TA (https=) |
| WO (1) | WO2014005036A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160145589A1 (en) | 2011-06-24 | 2016-05-26 | Green Cross Corporation | Composition and formulation comprising recombinant human iduronate-2-sulfatase and preparation method thereof |
| KR101380740B1 (ko) | 2012-06-29 | 2014-04-11 | 쉐어 휴먼 제네텍 세러피스, 인코포레이티드 | 이듀로네이트-2-설파타제의 정제 |
| US9150841B2 (en) | 2012-06-29 | 2015-10-06 | Shire Human Genetic Therapies, Inc. | Cells for producing recombinant iduronate-2-sulfatase |
| CA3140358A1 (en) * | 2012-07-31 | 2014-02-06 | Bioasis Technologies, Inc. | Dephosphorylated lysosomal storage disease proteins and methods of use thereof |
| AU2014243816B2 (en) | 2013-03-13 | 2019-01-31 | Bioasis Technologies Inc. | Fragments of p97 and uses thereof |
| DK3107562T3 (da) * | 2014-02-19 | 2019-12-16 | Bioasis Technologies Inc | P97-ids-fusionsproteiner |
| JP6785777B2 (ja) * | 2015-02-05 | 2020-11-18 | アール．ピー． シェーラー テクノロジーズ エルエルシー | 活性化ホルミルグリシン生成酵素ならびにその生成方法及び使用方法 |
| SG11201802933YA (en) * | 2015-10-07 | 2018-05-30 | Joel Huizenga | Resetting biological pathways for defending against and repairing deterioration from human aging |
| EP3373937B1 (en) | 2015-11-09 | 2021-12-22 | R.P. Scherer Technologies, LLC | Anti-cd22 antibody-maytansine conjugates and methods of use thereof |
| US11339775B2 (en) * | 2016-07-25 | 2022-05-24 | Repligen Corporation | Alternating tangential flow rapid harvesting |
| CR20200129A (es) | 2017-10-02 | 2020-08-22 | Denali Therapeutics Inc | Proteínas de fusión que comprenden enzimas de terapia de reemplazo de enzimas |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4330597A (en) | 1996-08-30 | 1998-03-19 | Life Technologies, Inc. | Serum-free mammalian cell culture medium, and uses thereof |
| US6506598B1 (en) * | 1999-04-26 | 2003-01-14 | Genentech, Inc. | Cell culture process |
| US6890736B1 (en) * | 2002-09-20 | 2005-05-10 | Immunex Corporation | Methods for producing proteins in cultured cells |
| CA2515708A1 (en) * | 2003-02-11 | 2004-08-26 | Transkaryotic Therapies, Inc. | Diagnosis and treatment of multiple sulfatase deficiency and other sulfatase deficiencies |
| US20050019914A1 (en) * | 2003-07-24 | 2005-01-27 | Aventis Pharma Deutschland Gmbh | Perfusion process for producing erythropoietin |
| WO2005113765A2 (en) * | 2004-05-06 | 2005-12-01 | Biomarin Pharmaceutical Inc. | Methods of activation of sulfatases and methods and compositions of using the same |
| AU2006254103B2 (en) * | 2005-06-03 | 2012-09-06 | Ares Trading S.A. | Production of recombinant IL-18 binding protein |
| WO2007067564A2 (en) * | 2005-12-08 | 2007-06-14 | Amgen Inc. | Improved host cells and culture methods |
| CA2711590C (en) | 2008-01-18 | 2021-03-23 | Biomarin Pharmaceutical Inc. | Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof |
| EP2485761B1 (en) * | 2009-10-09 | 2019-02-27 | Armagen, Inc. | Methods and compositions for increasing iduronate 2-sulfatase activity in the cns |
| US20130196410A1 (en) * | 2010-03-05 | 2013-08-01 | Alnylam Pharmaceuticals, Inc | Compositions and methods for modifying the glycosylation pattern of a polypeptide |
| KR20230159646A (ko) | 2010-06-25 | 2023-11-21 | 샤이어 휴먼 지네틱 테라피즈 인크. | 이듀로네이트-2-설파타제의 cns 전달을 위한 방법들 및 조성물들 |
| KR101158673B1 (ko) * | 2011-06-24 | 2012-07-03 | 주식회사 지씨바이오 | 재조합 인간 이듀로네이트-2-설파타아제를 포함하는 조성물, 제제 및 이의 제조방법 |
| US9150841B2 (en) * | 2012-06-29 | 2015-10-06 | Shire Human Genetic Therapies, Inc. | Cells for producing recombinant iduronate-2-sulfatase |
-
2013
- 2013-03-14 US US13/829,811 patent/US20140004097A1/en not_active Abandoned
- 2013-06-28 CN CN201380042616.9A patent/CN104583414A/zh active Pending
- 2013-06-28 WO PCT/US2013/048601 patent/WO2014005036A1/en not_active Ceased
- 2013-06-28 HK HK15110518.5A patent/HK1209790A1/xx unknown
- 2013-06-28 JP JP2015520577A patent/JP2015523074A/ja active Pending
- 2013-06-28 IN IN11272DEN2014 patent/IN2014DN11272A/en unknown
- 2013-06-28 PE PE2014002540A patent/PE20150603A1/es not_active Application Discontinuation
- 2013-06-28 CA CA2877492A patent/CA2877492A1/en not_active Abandoned
- 2013-06-28 EA EA201492185A patent/EA201492185A1/ru unknown
- 2013-06-28 EP EP13810106.8A patent/EP2867367A4/en not_active Withdrawn
- 2013-06-28 MX MX2015000188A patent/MX2015000188A/es unknown
- 2013-06-28 HK HK15110043.9A patent/HK1209458A1/xx unknown
- 2013-06-28 KR KR1020157002278A patent/KR20150037908A/ko not_active Withdrawn
- 2013-06-28 BR BR112014032544A patent/BR112014032544A2/pt not_active IP Right Cessation
- 2013-06-28 AU AU2013282417A patent/AU2013282417A1/en not_active Abandoned
- 2013-06-28 SG SG11201408755TA patent/SG11201408755TA/en unknown
-
2014
- 2014-12-17 CR CR20140587A patent/CR20140587A/es unknown
- 2014-12-17 IL IL236324A patent/IL236324A0/en unknown
- 2014-12-22 PH PH12014502870A patent/PH12014502870A1/en unknown
- 2014-12-22 DO DO2014000297A patent/DOP2014000297A/es unknown
- 2014-12-26 CO CO14284195A patent/CO7240395A2/es unknown
- 2014-12-29 CL CL2014003569A patent/CL2014003569A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1209458A1 (en) | 2016-04-01 |
| CA2877492A1 (en) | 2014-01-03 |
| PH12014502870A1 (en) | 2015-02-23 |
| KR20150037908A (ko) | 2015-04-08 |
| US20140004097A1 (en) | 2014-01-02 |
| CL2014003569A1 (es) | 2015-04-17 |
| IN2014DN11272A (https=) | 2015-10-09 |
| EA201492185A1 (ru) | 2015-10-30 |
| BR112014032544A2 (pt) | 2017-08-01 |
| SG11201408755TA (en) | 2015-02-27 |
| CN104583414A (zh) | 2015-04-29 |
| MX2015000188A (es) | 2015-04-08 |
| WO2014005036A1 (en) | 2014-01-03 |
| DOP2014000297A (es) | 2015-04-15 |
| EP2867367A4 (en) | 2016-02-24 |
| EP2867367A1 (en) | 2015-05-06 |
| IL236324A0 (en) | 2015-02-26 |
| AU2013282417A1 (en) | 2015-01-29 |
| CO7240395A2 (es) | 2015-04-17 |
| HK1209790A1 (en) | 2016-04-08 |
| CR20140587A (es) | 2015-04-06 |
| JP2015523074A (ja) | 2015-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |