PE20130403A1 - Comprimido de desintegracion via oral que contiene acarbosa - Google Patents

Comprimido de desintegracion via oral que contiene acarbosa

Info

Publication number
PE20130403A1
PE20130403A1 PE2012002079A PE2012002079A PE20130403A1 PE 20130403 A1 PE20130403 A1 PE 20130403A1 PE 2012002079 A PE2012002079 A PE 2012002079A PE 2012002079 A PE2012002079 A PE 2012002079A PE 20130403 A1 PE20130403 A1 PE 20130403A1
Authority
PE
Peru
Prior art keywords
disintegration tablet
oral disintegration
tablet containing
composition
acarbose
Prior art date
Application number
PE2012002079A
Other languages
English (en)
Inventor
Axel Schneeweis
Tobias Laich
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of PE20130403A1 publication Critical patent/PE20130403A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: (A) DE 1 A 30% DE ACARBOSA QUE TIENE UN TAMANO MEDIO DE PARTICULA DE 100 A 600 ?m; (B) DE 40 A 90% DE UN VEHICULO SOLUBLE EN AGUA; (C) DE UN 1 A 50% DE UN VEHICULO INSOLUBLE EN AGUA. LA COMPOSICION ESTA EN FORMA DE COMPRIMIDO DE DESINTEGRACION POR VIA ORAL QUE PRESENTA UN TIEMPO DE DESINTEGRACION DE NO MENOS DE 60 SEGUNDOS. REFERIDA ADEMAS A UN PROCEDIMIENTO DE PREPARACION DE DICHO COMPRIMIDO. DICHA COMPOSICION PRESENTA UNA DISOLUCION Y LIBERACION DEL PRINCIPIO ACTIVO MEJORADO SIENDO UTIL EN EL TRATAMIENTO DE DIABETES MELLITUS.
PE2012002079A 2010-04-27 2011-04-26 Comprimido de desintegracion via oral que contiene acarbosa PE20130403A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10161114 2010-04-27

Publications (1)

Publication Number Publication Date
PE20130403A1 true PE20130403A1 (es) 2013-04-13

Family

ID=44344015

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2012002079A PE20130403A1 (es) 2010-04-27 2011-04-26 Comprimido de desintegracion via oral que contiene acarbosa

Country Status (26)

Country Link
US (1) US20130131003A1 (es)
EP (1) EP2563329B1 (es)
JP (1) JP5944378B2 (es)
KR (1) KR101788350B1 (es)
CN (2) CN102905687A (es)
AU (1) AU2011247642C1 (es)
BR (1) BR112012027303A2 (es)
CA (1) CA2797365A1 (es)
CL (1) CL2012003011A1 (es)
CO (1) CO6640213A2 (es)
CR (1) CR20120548A (es)
CU (1) CU20120152A7 (es)
DO (1) DOP2012000277A (es)
EC (1) ECSP12012279A (es)
ES (1) ES2623025T3 (es)
GT (1) GT201200290A (es)
IL (1) IL222368B (es)
MX (1) MX348865B (es)
MY (1) MY179724A (es)
NZ (1) NZ603199A (es)
PE (1) PE20130403A1 (es)
SG (2) SG184851A1 (es)
SI (1) SI2563329T1 (es)
TW (1) TWI556823B (es)
UA (1) UA111155C2 (es)
WO (1) WO2011134962A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201100150A2 (tr) * 2011-01-06 2012-07-23 Bi̇lgi̇ç Mahmut Suda çözünür dozaj formları
WO2013115741A1 (en) * 2012-01-31 2013-08-08 Mahmut Bilgic Pharmaceutical compositions comprising alpha-glucosidase inhibitor
WO2013115738A1 (en) * 2012-01-31 2013-08-08 Mahmut Bilgic Micronized acarbose
CA2922849A1 (en) 2012-08-31 2014-03-06 Ixchel Pharma, Llc Agents useful for treating obesity, diabetes and related disorders
CN104013590A (zh) * 2014-05-09 2014-09-03 万特制药(海南)有限公司 一种含阿卡波糖的药物组合物及其制备方法
EP3233066B1 (en) 2014-12-17 2021-11-10 Empros Pharma AB A modified release composition of orlistat and acarbose for the treatment of obesity and related metabolic disorders
CN105213341A (zh) * 2015-10-29 2016-01-06 无锡福祈制药有限公司 一种阿卡波糖片及其制备方法
CN113081984B (zh) * 2021-04-19 2023-06-02 北京阳光诺和药物研究股份有限公司 一种阿卡波糖口崩片及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3134591A1 (de) * 1981-09-01 1983-03-10 Bayer Ag, 5090 Leverkusen Neue arzneimittelpraeparationen fuer glykosidhydrolasen-inhibitoren
JPH10182687A (ja) * 1996-10-21 1998-07-07 Bayer Yakuhin Kk アカルボースの貯蔵安定化法
DE19802700A1 (de) * 1998-01-24 1999-07-29 Bayer Ag Verfahren zur Herstellung einer im Mund schnell zerfallenden Arzneiform, die als Wirkstoff Acarbose enthält
US20040081697A1 (en) * 1998-11-12 2004-04-29 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
KR100682836B1 (ko) * 2004-12-06 2007-02-15 엘지전자 주식회사 유기 전계 발광 소자
US20060229261A1 (en) * 2005-04-12 2006-10-12 John Devane Acarbose methods and formulations for treating chronic constipation
MY157620A (en) * 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
WO2007099908A1 (ja) * 2006-02-27 2007-09-07 Matsushita Electric Industrial Co., Ltd. ウェアラブル端末、および、携帯撮像収音装置、およびそれらを実現する装置、方法、プログラム
FI20070521L (fi) * 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
CN101411715B (zh) * 2007-10-19 2012-03-28 杭州华东医药集团生物工程研究所有限公司 含有阿卡波糖的药物组合物
JP5291324B2 (ja) * 2007-11-01 2013-09-18 沢井製薬株式会社 口腔内崩壊錠
JP2009114113A (ja) * 2007-11-06 2009-05-28 Nipro Corp 口腔内崩壊錠及びその製造方法
RU2010128019A (ru) * 2007-12-08 2012-01-20 Байер Шеринг Фарма Акциенгезельшафт (DE) Пероральная диспергируемая таблетка
AR069875A1 (es) * 2007-12-21 2010-02-24 Eurand Inc Composiciones de temazepam para tabletas de desintegracion oral y metodo de preparacion
CN102088959B (zh) * 2008-06-20 2016-05-25 默克专利股份有限公司 可直接压缩的且快速崩解的片剂基质

Also Published As

Publication number Publication date
JP5944378B2 (ja) 2016-07-05
CN102905687A (zh) 2013-01-30
NZ603199A (en) 2014-05-30
CA2797365A1 (en) 2011-11-03
ECSP12012279A (es) 2012-11-30
AU2011247642A1 (en) 2012-11-08
US20130131003A1 (en) 2013-05-23
EP2563329B1 (en) 2017-04-12
MY179724A (en) 2020-11-11
KR20130062926A (ko) 2013-06-13
CO6640213A2 (es) 2013-03-22
MX348865B (es) 2017-07-03
IL222368B (en) 2018-11-29
IL222368A0 (en) 2012-12-31
WO2011134962A3 (en) 2012-05-03
CN106924199A (zh) 2017-07-07
GT201200290A (es) 2014-09-24
UA111155C2 (uk) 2016-04-11
MX2012012459A (es) 2012-11-21
EP2563329A2 (en) 2013-03-06
ES2623025T3 (es) 2017-07-10
CL2012003011A1 (es) 2013-04-19
WO2011134962A2 (en) 2011-11-03
SI2563329T1 (sl) 2017-05-31
TWI556823B (zh) 2016-11-11
AU2011247642B2 (en) 2015-05-14
SG184851A1 (en) 2012-11-29
CR20120548A (es) 2013-03-11
BR112012027303A2 (pt) 2017-10-24
JP2013525404A (ja) 2013-06-20
TW201141490A (en) 2011-12-01
AU2011247642C1 (en) 2015-11-12
DOP2012000277A (es) 2012-12-15
KR101788350B1 (ko) 2017-10-19
SG10201505844WA (en) 2015-09-29
CU20120152A7 (es) 2014-02-28

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