PE20120324A1 - Combinacion que comprende (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida y donezepilo como moduladora de trastornos cognitivos - Google Patents
Combinacion que comprende (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida y donezepilo como moduladora de trastornos cognitivosInfo
- Publication number
- PE20120324A1 PE20120324A1 PE2011001948A PE2011001948A PE20120324A1 PE 20120324 A1 PE20120324 A1 PE 20120324A1 PE 2011001948 A PE2011001948 A PE 2011001948A PE 2011001948 A PE2011001948 A PE 2011001948A PE 20120324 A1 PE20120324 A1 PE 20120324A1
- Authority
- PE
- Peru
- Prior art keywords
- quinuclidin
- carboxamide
- thiophene
- benzo
- donezepyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE CONTIENE: A) UN AGONISTA DEL RECEPTOR NICOTINICO DE ACETILCOLINA (nAChR) ALFA 7 TAL COMO (R)-7-CLORO-N-(QUINUCLIDIN-3-IL)BENZO[b]TIOFENO-2-CARBOXAMIDA QUE SE ENCUENTRA EN UNA CANTIDAD DE HASTA 1MG; Y B) UN INHIBIDOR DE ACETILCOLINESTERASA TAL COMO DONEPEZILO, RIVASTIGMINA, GALANTAMINA O TACRINA, EN DONDE EL DONEPEZILO SE ENCUENTRA EN UNA CANTIDAD DE HASTA 5MG. TAMBIEN SE REFIERE A UN METODO PARA MEJORAR LA COGNICION. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17726009P | 2009-05-11 | 2009-05-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20120324A1 true PE20120324A1 (es) | 2012-04-17 |
Family
ID=42306679
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2011001948A PE20120324A1 (es) | 2009-05-11 | 2010-05-11 | Combinacion que comprende (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida y donezepilo como moduladora de trastornos cognitivos |
Country Status (15)
Country | Link |
---|---|
US (2) | US20110124631A1 (es) |
EP (1) | EP2429518A1 (es) |
JP (1) | JP5808319B2 (es) |
CN (1) | CN102802620A (es) |
AU (1) | AU2010247835A1 (es) |
BR (1) | BRPI1014793A2 (es) |
CA (1) | CA2761716A1 (es) |
CL (1) | CL2011002847A1 (es) |
CO (1) | CO6460746A2 (es) |
EC (1) | ECSP11011453A (es) |
IL (1) | IL216281A0 (es) |
MX (1) | MX2011011972A (es) |
PE (1) | PE20120324A1 (es) |
RU (1) | RU2011150248A (es) |
WO (1) | WO2010132423A1 (es) |
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DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
PT3029039T (pt) | 2010-05-17 | 2017-11-28 | Forum Pharmaceuticals Inc | Formulações farmacêuticas que compreendem formas cristalinas de cloridrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo(b)tiofeno-2-carboxamida mono-hidratado |
EP2640378A4 (en) * | 2010-11-18 | 2014-05-21 | Envivo Pharmaceuticals Inc | INFLAMMATION TREATMENT WITH CERTAIN NICOTINIC ACID ALPHA-7 RECEPTOR AGONISTS IN COMBINATION WITH ACETYLCHOLINESTERASE INHIBITORS |
US20140155429A1 (en) * | 2011-05-09 | 2014-06-05 | Envivo Pharmaceuticals, Inc. | Treatment of Cognitive Disorders with Certain Alpha-7 Nicotinic Acid Receptor Agonists in Combination with Nicotine |
WO2012177856A2 (en) * | 2011-06-21 | 2012-12-27 | Adispell, Inc. | Cognition modification |
KR20140027939A (ko) | 2011-06-30 | 2014-03-07 | 도레이 카부시키가이샤 | 지양제 |
RU2014103474A (ru) * | 2011-07-01 | 2015-08-10 | Энвиво Фармасьютикалз, Инк. | Способы лечения умеренных когнитивных нарушений |
CA2872005A1 (en) * | 2012-05-08 | 2013-11-14 | Forum Pharmaceuticals, Inc. | Methods of maintaining, treating or improving cognitive function |
CN103333163A (zh) * | 2013-07-09 | 2013-10-02 | 广州中医药大学 | 一种苯并呋喃类衍生物及其制备方法和应用 |
US10561665B2 (en) | 2014-03-25 | 2020-02-18 | Synaptec Development Llc | Treatment of autism |
FR3020819B1 (fr) | 2014-05-12 | 2020-02-14 | Arkema France | Procede d'impregnation de fibres naturelles par un polymere en dispersion aqueuse et utilisation desdites fibres dans les materiaux composites. |
AU2016264228B2 (en) * | 2015-05-18 | 2019-06-13 | Synaptec Development Llc | Galantamine clearance of amyloidß |
RU2759727C2 (ru) | 2017-06-02 | 2021-11-17 | ФУДЖИФИЛМ Тояма Кемикал Ко., Лтд. | Средство для профилактики или лечения атрофии головного мозга |
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2010
- 2010-05-11 RU RU2011150248/02A patent/RU2011150248A/ru unknown
- 2010-05-11 CA CA 2761716 patent/CA2761716A1/en not_active Abandoned
- 2010-05-11 CN CN2010800312022A patent/CN102802620A/zh active Pending
- 2010-05-11 BR BRPI1014793A patent/BRPI1014793A2/pt not_active IP Right Cessation
- 2010-05-11 MX MX2011011972A patent/MX2011011972A/es not_active Application Discontinuation
- 2010-05-11 WO PCT/US2010/034353 patent/WO2010132423A1/en active Application Filing
- 2010-05-11 PE PE2011001948A patent/PE20120324A1/es not_active Application Discontinuation
- 2010-05-11 EP EP20100718403 patent/EP2429518A1/en not_active Withdrawn
- 2010-05-11 JP JP2012510926A patent/JP5808319B2/ja not_active Expired - Fee Related
- 2010-05-11 AU AU2010247835A patent/AU2010247835A1/en not_active Abandoned
- 2010-12-27 US US12/979,139 patent/US20110124631A1/en not_active Abandoned
-
2011
- 2011-11-10 IL IL216281A patent/IL216281A0/en unknown
- 2011-11-11 CO CO11153648A patent/CO6460746A2/es not_active Application Discontinuation
- 2011-11-11 EC ECSP11011453 patent/ECSP11011453A/es unknown
- 2011-11-11 CL CL2011002847A patent/CL2011002847A1/es unknown
-
2014
- 2014-06-17 US US14/307,139 patent/US20150126546A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2429518A1 (en) | 2012-03-21 |
US20110124631A1 (en) | 2011-05-26 |
JP2012526821A (ja) | 2012-11-01 |
CN102802620A (zh) | 2012-11-28 |
IL216281A0 (en) | 2012-01-31 |
CA2761716A1 (en) | 2010-11-18 |
WO2010132423A1 (en) | 2010-11-18 |
RU2011150248A (ru) | 2013-06-20 |
CO6460746A2 (es) | 2012-06-15 |
AU2010247835A1 (en) | 2011-12-08 |
ECSP11011453A (es) | 2011-12-30 |
BRPI1014793A2 (pt) | 2016-04-05 |
CL2011002847A1 (es) | 2012-07-20 |
MX2011011972A (es) | 2011-12-08 |
US20150126546A1 (en) | 2015-05-07 |
JP5808319B2 (ja) | 2015-11-10 |
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