PE20100050A1 - Forma de dosificacion farmaceutica para la liberacion inmediata de un derivado de indolinona - Google Patents
Forma de dosificacion farmaceutica para la liberacion inmediata de un derivado de indolinonaInfo
- Publication number
- PE20100050A1 PE20100050A1 PE2009000780A PE2009000780A PE20100050A1 PE 20100050 A1 PE20100050 A1 PE 20100050A1 PE 2009000780 A PE2009000780 A PE 2009000780A PE 2009000780 A PE2009000780 A PE 2009000780A PE 20100050 A1 PE20100050 A1 PE 20100050A1
- Authority
- PE
- Peru
- Prior art keywords
- dosage form
- pharmaceutical dosage
- immediate release
- indolinone derivative
- indolinone
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 title abstract 2
- 239000012729 immediate-release (IR) formulation Substances 0.000 title 1
- JYGFTBXVXVMTGB-UHFFFAOYSA-N indolin-2-one Chemical class C1=CC=C2NC(=O)CC2=C1 JYGFTBXVXVMTGB-UHFFFAOYSA-N 0.000 title 1
- -1 TABLET Substances 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940100688 oral solution Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B19/00—Teaching not covered by other main groups of this subclass
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Business, Economics & Management (AREA)
- Physics & Mathematics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Entrepreneurship & Innovation (AREA)
- Dispersion Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Educational Administration (AREA)
- Educational Technology (AREA)
- General Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
REFERIDA A UNA FORMA DE DOSIFICACION FARMACEUTICA TAL COMO COMPRIMIDO, CAPSULA, SOLUCION ORAL, ELIXIR, EMULSION, MICROGRANULOS, POLVO O GRANULOS, DE UNA SUSTANCIA ACTIVA TAL COMO 3-Z-[1-(4-(N-((4-METIL-PIPERAZIN-1-IL)-METILCARBONIL)-N-METIL-AMINO)-ANILINO)-1-FENIL-METILENO]-6-METOXICARBONIL-2-INDOLINONA-MONOETANOSULFONATO EN UNA CONCENTRACION DE 0,01% A 90% EN PESO DE LA COMPOSICION
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08157750 | 2008-06-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20100050A1 true PE20100050A1 (es) | 2010-01-29 |
Family
ID=41017080
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2009000780A PE20100050A1 (es) | 2008-06-06 | 2009-06-04 | Forma de dosificacion farmaceutica para la liberacion inmediata de un derivado de indolinona |
Country Status (35)
Country | Link |
---|---|
US (3) | US20110190318A1 (es) |
EP (1) | EP2313087B2 (es) |
JP (2) | JP5583119B2 (es) |
KR (1) | KR20110022586A (es) |
CN (1) | CN102056599A (es) |
AR (1) | AR072060A1 (es) |
AU (1) | AU2009254556B2 (es) |
BR (1) | BRPI0913235A2 (es) |
CA (1) | CA2726648A1 (es) |
CL (1) | CL2010001362A1 (es) |
CO (1) | CO6280468A2 (es) |
CY (1) | CY1121272T1 (es) |
DK (1) | DK2313087T4 (es) |
EA (1) | EA201001857A1 (es) |
EC (1) | ECSP10010717A (es) |
ES (1) | ES2711913T5 (es) |
FI (1) | FI2313087T4 (es) |
HR (1) | HRP20190181T4 (es) |
HU (1) | HUE042524T2 (es) |
IL (1) | IL209055A0 (es) |
LT (1) | LT2313087T (es) |
MA (1) | MA32386B1 (es) |
MX (1) | MX338001B (es) |
PE (1) | PE20100050A1 (es) |
PL (1) | PL2313087T5 (es) |
PT (1) | PT2313087T (es) |
RS (1) | RS58280B2 (es) |
SG (1) | SG191607A1 (es) |
SI (1) | SI2313087T2 (es) |
TR (1) | TR201901579T4 (es) |
TW (1) | TW201002692A (es) |
UA (1) | UA107560C2 (es) |
UY (1) | UY31876A (es) |
WO (1) | WO2009147220A1 (es) |
ZA (1) | ZA201007972B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040077604A1 (en) * | 2001-12-19 | 2004-04-22 | Lenard Lichtenberger | Method and compositions employing formulations of lecithin oils and nsaids for protecting the gastrointestinal tract and providingenhanced therapeutic activity |
NZ603162A (en) | 2008-06-06 | 2014-05-30 | Boehringer Ingelheim Int | Capsule pharmaceutical dosage form comprising a suspension formulation of an indolinone derivative |
AU2013322640A1 (en) | 2012-09-28 | 2015-03-12 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations comprising dual Angiopoietin-2 / Dll4 binders and anti-VEGF-R agents |
US20140350022A1 (en) | 2013-05-10 | 2014-11-27 | Boehringer Ingelheim International Gmbh | Efficacious treatment of NSCLC and predictive clinical marker of the responsiveness of a tumour to a treatment |
CA2913731C (en) | 2013-06-04 | 2021-05-25 | Monosol Llc | Water-soluble film sealing solutions, related methods, and related articles |
EP3782604A1 (en) | 2013-07-31 | 2021-02-24 | Windward Pharma, Inc. | Aerosol tyrosine kinase inhibitor compounds and uses thereof |
EP3551187B1 (en) | 2016-12-12 | 2021-02-17 | Boehringer Ingelheim International GmbH | Nintedanib for use in methods for the treatment of interstitial lung diseases by coadministration with olodaterol |
EP3600322A1 (en) * | 2017-03-28 | 2020-02-05 | Boehringer Ingelheim International GmbH | Nintedanib for use in methods for the treatment of muscular dystrophy |
AU2018357775B2 (en) | 2017-10-23 | 2024-02-15 | Boehringer Ingelheim International Gmbh | New combination of active agents for the treatment of progressive fibrosing interstitial lung diseases (PF-ILD) |
TW201938158A (zh) | 2018-03-07 | 2019-10-01 | 美商普萊恩醫療公司 | 胺基酸化合物及使用方法 |
JP2023519600A (ja) | 2020-04-01 | 2023-05-11 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 線維性状態の治療におけるバイオマーカーの使用 |
EP4098246A1 (en) | 2021-05-31 | 2022-12-07 | Lotus Pharmaceutical Co., Ltd. | Formulation of nintedanib |
WO2024037982A1 (en) | 2022-08-16 | 2024-02-22 | Boehringer Ingelheim International Gmbh | Pharmaceutical formulations of nintedanib for intraocular use |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3579384D1 (de) | 1984-07-24 | 1990-10-04 | Scherer Gmbh R P | Oxytetracyclin-hc1-weichgelatinekapseln und verfahren zu ihrer herstellung. |
DE19603402A1 (de) | 1995-02-24 | 1996-08-29 | Basf Ag | Weichgelatinekapseln |
US6762180B1 (en) | 1999-10-13 | 2004-07-13 | Boehringer Ingelheim Pharma Kg | Substituted indolines which inhibit receptor tyrosine kinases |
DE10233500A1 (de) * | 2002-07-24 | 2004-02-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylen]-6-methoxycarbonyl-2-indolinon-Monoethansulfonat und dessen Verwendung als Arzneimittel |
US20050043233A1 (en) * | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
US20060058311A1 (en) * | 2004-08-14 | 2006-03-16 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation |
PE20060777A1 (es) * | 2004-12-24 | 2006-10-06 | Boehringer Ingelheim Int | Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas |
PL1948180T3 (pl) * | 2005-11-11 | 2013-09-30 | Boehringer Ingelheim Int | Terapia skojarzona raka polegająca na podawaniu inhibitorów EGFR/HER2 |
NZ603162A (en) * | 2008-06-06 | 2014-05-30 | Boehringer Ingelheim Int | Capsule pharmaceutical dosage form comprising a suspension formulation of an indolinone derivative |
LT2985025T (lt) * | 2008-06-06 | 2018-04-10 | Boehringer Ingelheim International Gmbh | Farmacinis derinys |
EP2387401A1 (en) * | 2009-01-14 | 2011-11-23 | Boehringer Ingelheim International GmbH | Method for treating colorectal cancer |
US8802384B2 (en) * | 2009-03-12 | 2014-08-12 | Boehringer Ingelheim International Gmbh | Method or system using biomarkers for the monitoring of a treatment |
JP2012526766A (ja) * | 2009-05-14 | 2012-11-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 腫瘍性及び線維性疾患の処置における新規な併用療法 |
-
2009
- 2009-04-06 UA UAA201100096A patent/UA107560C2/ru unknown
- 2009-06-04 RS RS20190128A patent/RS58280B2/sr unknown
- 2009-06-04 FI FIEP09757601.1T patent/FI2313087T4/fi active
- 2009-06-04 LT LTEP09757601.1T patent/LT2313087T/lt unknown
- 2009-06-04 CN CN200980121070XA patent/CN102056599A/zh active Pending
- 2009-06-04 TR TR2019/01579T patent/TR201901579T4/tr unknown
- 2009-06-04 HU HUE09757601A patent/HUE042524T2/hu unknown
- 2009-06-04 BR BRPI0913235A patent/BRPI0913235A2/pt not_active IP Right Cessation
- 2009-06-04 EP EP09757601.1A patent/EP2313087B2/en active Active
- 2009-06-04 US US12/995,893 patent/US20110190318A1/en not_active Abandoned
- 2009-06-04 WO PCT/EP2009/056895 patent/WO2009147220A1/en active Application Filing
- 2009-06-04 AU AU2009254556A patent/AU2009254556B2/en active Active
- 2009-06-04 PE PE2009000780A patent/PE20100050A1/es not_active Application Discontinuation
- 2009-06-04 SG SG2013040332A patent/SG191607A1/en unknown
- 2009-06-04 DK DK09757601.1T patent/DK2313087T4/da active
- 2009-06-04 CA CA2726648A patent/CA2726648A1/en not_active Abandoned
- 2009-06-04 PL PL09757601.1T patent/PL2313087T5/pl unknown
- 2009-06-04 KR KR1020107027313A patent/KR20110022586A/ko not_active Application Discontinuation
- 2009-06-04 HR HRP20190181TT patent/HRP20190181T4/hr unknown
- 2009-06-04 SI SI200931930T patent/SI2313087T2/sl unknown
- 2009-06-04 JP JP2011512134A patent/JP5583119B2/ja active Active
- 2009-06-04 ES ES09757601T patent/ES2711913T5/es active Active
- 2009-06-04 MX MX2010013092A patent/MX338001B/es active IP Right Grant
- 2009-06-04 EA EA201001857A patent/EA201001857A1/ru unknown
- 2009-06-04 PT PT09757601T patent/PT2313087T/pt unknown
- 2009-06-05 TW TW098118827A patent/TW201002692A/zh unknown
- 2009-06-05 AR ARP090102040A patent/AR072060A1/es unknown
- 2009-06-08 UY UY0001031876A patent/UY31876A/es not_active Application Discontinuation
-
2010
- 2010-11-01 IL IL209055A patent/IL209055A0/en unknown
- 2010-11-08 ZA ZA2010/07972A patent/ZA201007972B/en unknown
- 2010-12-03 CO CO10152530A patent/CO6280468A2/es not_active Application Discontinuation
- 2010-12-06 MA MA33403A patent/MA32386B1/fr unknown
- 2010-12-06 CL CL2010001362A patent/CL2010001362A1/es unknown
- 2010-12-23 EC EC2010010717A patent/ECSP10010717A/es unknown
-
2013
- 2013-03-08 US US13/790,334 patent/US20130203773A1/en not_active Abandoned
-
2014
- 2014-02-10 US US14/176,478 patent/US20140163040A1/en not_active Abandoned
- 2014-02-28 JP JP2014039871A patent/JP5992937B2/ja active Active
-
2019
- 2019-02-19 CY CY20191100212T patent/CY1121272T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20100050A1 (es) | Forma de dosificacion farmaceutica para la liberacion inmediata de un derivado de indolinona | |
UY31879A (es) | Forma de dosificación farmacéutica en cápsula que comprende una formulación en suspensión de un derivado de indolinona | |
UY32156A (es) | Derivados sustituidos de la n2 - [1-(5 - fluoropirimidin -2-il) etil] - n4 - (1-metil - 1h-imidazol - 4 - il)) - pirimidina - 2,4 - diaminas y sus sales farmacéuticamente aceptables, proceso de preparación, composiciones conteniéndolos y aplicaciones. | |
EA201071288A1 (ru) | Тризамещенные пиразолы в качестве модуляторов рецепторов ацетилхолина | |
EA201290394A1 (ru) | Морфолинотиазолы в качестве позитивных аллостерических модуляторов альфа 7 | |
HK1149258A1 (en) | Compounds | |
EA201490014A1 (ru) | Модифицированное высвобождение 4-метил-3-[[4-(3-пиридинил)-2-пиримидинил]амино]-n-[5-(4-метил-1h-имидазол-1-ил)-3-(трифторметил)фенил]бензамида, солюбилизированного с использованием органических кислот | |
PE20140604A1 (es) | Combinacion de panobinostat y ruxolitinib en el tratamiento del cancer tal como una neoplasia mieloproliferativa | |
EA200901138A1 (ru) | Производные дианилинопиримидина как ингибиторы киназы wee1, фармацевтическая композиция и применение | |
EA201071094A1 (ru) | Тризамещенные 1,2,4-триазолы в качестве модуляторов никотиновых ацетилхолиновых рецепторов | |
EA201170198A1 (ru) | Фармацевтические композиции, содержащие лиганды рецептора дофамина | |
EA201201050A1 (ru) | Пиразолы в качестве антагонистов crth2 | |
EA201291421A1 (ru) | Пероральные фармацевтические лекарственные формы, содержащие дабигатрана этексилат и его фармацевтически приемлемые соли | |
EA201691322A1 (ru) | Фармацевтическая композиция ингибитора dpp-iv в комбинации с метформином | |
EA201270428A1 (ru) | Замещенные n-фенил-1-(4-пиридинил)-1н-пиразол-3-амины | |
EA201200616A1 (ru) | Производные 2-оксо-1-пирролидинилимидазотиадиазола | |
TNSN07337A1 (en) | Pharmaceutical composition comprising an indolylmaleimide derivative | |
PH12015500823A1 (en) | Modified release formulations for oprozomib | |
CY1113551T1 (el) | Υποκατεστημενες ενωσεις νικοτιναμιδιου και η χρησιμοποιηση τους σε φαρμακα | |
MX2017016862A (es) | Composicion farmaceutica estable para administracion oral. | |
EA200900254A1 (ru) | Производные 1h-индол-2-карбоновой кислоты, полезные в качестве модуляторов ppar | |
EA201691034A1 (ru) | Композиции в твердой форме с замедленным высвобождением для перорального введения | |
ATE522515T1 (de) | Modulatoren der dopamin-neurotransmission | |
EA201891027A1 (ru) | Фармацевтическая композиция, содержащая производные индола, способ ее получения и применение | |
EA201170843A1 (ru) | Предварительно спрессованные быстро распадающиеся лекарственные формы соединений с низкой пероральной биодоступностью |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed |