PE20090438A1 - Formulaciones estables de derivado de tiadiazol - Google Patents

Formulaciones estables de derivado de tiadiazol

Info

Publication number
PE20090438A1
PE20090438A1 PE2008001141A PE2008001141A PE20090438A1 PE 20090438 A1 PE20090438 A1 PE 20090438A1 PE 2008001141 A PE2008001141 A PE 2008001141A PE 2008001141 A PE2008001141 A PE 2008001141A PE 20090438 A1 PE20090438 A1 PE 20090438A1
Authority
PE
Peru
Prior art keywords
stable
tiadiazole
dimethyl
derivative formulations
compound
Prior art date
Application number
PE2008001141A
Other languages
English (en)
Inventor
Hiroko Kusano
Yoshikazu Tashiro
Yosuke Watanabe
Hong Zhuang
Dinesh Shyamdeo Mishra
Original Assignee
Lilly Co Eli
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39735000&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20090438(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli, Kyowa Hakko Kogyo Kk filed Critical Lilly Co Eli
Publication of PE20090438A1 publication Critical patent/PE20090438A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: EL COMPUESTO N-{4-(2,2-DIMETIL-PROPONIL)-(5R)-5-[(2-ETILAMINO-ETANSULFONILAMINO)-METIL]-5-FENIL-4,5-DIHIDRO-[1,3,4]TIADIAZOL-2-IL}-2,2-DIMETIL-PROPIONAMIDA Y UN DILUYENTE FARMACEUTICAMENTE ACEPTABLE. EN DONDE EL pH DE DICHA COMPOSICION ES MENOS DE 6.4 Y MAYOR DE 2.0. LAS FORMULACIONES ESTABLES DEL COMPUESTO MINIMIZAN LA CONVERSION QUIRAL A LA FORMA ENANTIOMERICA S MENOS ACTIVA, SIENDO UTIL PARA EL TRATAMIENTO DEL TUMOR MALIGNO
PE2008001141A 2007-07-12 2008-07-07 Formulaciones estables de derivado de tiadiazol PE20090438A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94926807P 2007-07-12 2007-07-12

Publications (1)

Publication Number Publication Date
PE20090438A1 true PE20090438A1 (es) 2009-04-18

Family

ID=39735000

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2008001141A PE20090438A1 (es) 2007-07-12 2008-07-07 Formulaciones estables de derivado de tiadiazol

Country Status (28)

Country Link
US (1) US8222284B2 (es)
EP (1) EP2178508B1 (es)
JP (1) JP4875205B2 (es)
KR (1) KR101188036B1 (es)
CN (1) CN101730525A (es)
AR (1) AR067472A1 (es)
AU (1) AU2008275258A1 (es)
BR (1) BRPI0814039A2 (es)
CA (1) CA2694277C (es)
CL (1) CL2008001996A1 (es)
CO (1) CO6270304A2 (es)
CR (1) CR11210A (es)
DO (1) DOP2010000004A (es)
EA (1) EA016861B1 (es)
EC (1) ECSP109864A (es)
ES (1) ES2401477T3 (es)
GT (1) GT201000003A (es)
HK (1) HK1141238A1 (es)
IL (1) IL202382A0 (es)
MA (1) MA31880B1 (es)
MX (1) MX2010000468A (es)
NZ (1) NZ581791A (es)
PE (1) PE20090438A1 (es)
SV (1) SV2010003449A (es)
TN (1) TN2010000015A1 (es)
TW (1) TW200918050A (es)
UA (1) UA97672C2 (es)
WO (1) WO2009009470A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010150404A1 (ja) 2009-06-26 2010-12-29 三菱電機株式会社 冷媒圧縮機

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1454903B9 (en) 2001-12-11 2011-10-05 Kyowa Hakko Kirin Co., Ltd. Thiadiazoline derivatives for treating cancer
ES2377498T3 (es) * 2003-04-18 2012-03-28 Kyowa Hakko Kirin Co., Ltd. Inhibidor de quinesina en etapa M
KR20070113300A (ko) * 2005-03-22 2007-11-28 교와 핫꼬 고교 가부시끼가이샤 고형종양 치료제
EP1870404A4 (en) * 2005-03-22 2010-07-14 Kyowa Hakko Kirin Co Ltd MEANS FOR THE TREATMENT OF A HEMATOPOIETIC TUMOR
JP2008137893A (ja) * 2005-03-22 2008-06-19 Kyowa Hakko Kogyo Co Ltd 関節炎治療剤
JP2008150291A (ja) * 2005-03-22 2008-07-03 Kyowa Hakko Kogyo Co Ltd 乾癬治療剤
JP2006265107A (ja) * 2005-03-22 2006-10-05 Kyowa Hakko Kogyo Co Ltd 緑内障治療剤
EP1908755A4 (en) * 2005-06-24 2009-06-24 Kyowa Hakko Kirin Co Ltd THERAPEUTIC AGENT AGAINST RESTENOSIS

Also Published As

Publication number Publication date
AU2008275258A1 (en) 2009-01-15
KR101188036B1 (ko) 2012-10-05
ECSP109864A (es) 2010-03-31
TW200918050A (en) 2009-05-01
KR20100029827A (ko) 2010-03-17
SV2010003449A (es) 2010-08-10
CA2694277A1 (en) 2009-01-15
CO6270304A2 (es) 2011-04-20
JP2010533190A (ja) 2010-10-21
TN2010000015A1 (en) 2011-09-26
MA31880B1 (fr) 2010-12-01
EA016861B1 (ru) 2012-08-30
JP4875205B2 (ja) 2012-02-15
CL2008001996A1 (es) 2009-05-22
UA97672C2 (ru) 2012-03-12
MX2010000468A (es) 2010-04-09
US8222284B2 (en) 2012-07-17
US20110009458A1 (en) 2011-01-13
EA201070136A1 (ru) 2010-06-30
HK1141238A1 (en) 2010-11-05
CN101730525A (zh) 2010-06-09
EP2178508B1 (en) 2013-02-06
AR067472A1 (es) 2009-10-14
BRPI0814039A2 (pt) 2017-10-03
CR11210A (es) 2010-06-23
EP2178508A1 (en) 2010-04-28
ES2401477T3 (es) 2013-04-19
GT201000003A (es) 2012-03-13
IL202382A0 (en) 2010-06-30
CA2694277C (en) 2013-04-09
WO2009009470A1 (en) 2009-01-15
DOP2010000004A (es) 2010-03-15
NZ581791A (en) 2012-03-30

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Legal Events

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FD Application declared void or lapsed