DOP2010000004A - Formulaciones estables de derivado de tiadiazol - Google Patents

Formulaciones estables de derivado de tiadiazol

Info

Publication number
DOP2010000004A
DOP2010000004A DO2010000004A DO2010000004A DOP2010000004A DO P2010000004 A DOP2010000004 A DO P2010000004A DO 2010000004 A DO2010000004 A DO 2010000004A DO 2010000004 A DO2010000004 A DO 2010000004A DO P2010000004 A DOP2010000004 A DO P2010000004A
Authority
DO
Dominican Republic
Prior art keywords
tiadiazol
derivative
stable formulations
dimethyl
stable
Prior art date
Application number
DO2010000004A
Other languages
English (en)
Inventor
Dinesh Shyamdeo Mishra
Yoshikazu Tashiro
Yosuke Watanabe
Hong Zhuang
Hiroko Kusano
Original Assignee
Lilly Co Eli
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39735000&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2010000004(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli, Kyowa Hakko Kogyo Kk filed Critical Lilly Co Eli
Publication of DOP2010000004A publication Critical patent/DOP2010000004A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere parametros de formulación y condiciones de manufacturación para composiciones farmaceuticas estables que comprenden N-{4 (2,2-dimetil-propionil)-(5R)-5-[(2-etilamino-etansulfonilamino)-metil]-5-fenil-4,5-dihidro-[1,3,4]tiadiazol-2-il}-2,2-dimetil-propionamida que minimiza la conversión quiral estable a la forma enantiomerica S menos activa.
DO2010000004A 2007-07-12 2010-01-07 Formulaciones estables de derivado de tiadiazol DOP2010000004A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94926807P 2007-07-12 2007-07-12

Publications (1)

Publication Number Publication Date
DOP2010000004A true DOP2010000004A (es) 2010-03-15

Family

ID=39735000

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2010000004A DOP2010000004A (es) 2007-07-12 2010-01-07 Formulaciones estables de derivado de tiadiazol

Country Status (28)

Country Link
US (1) US8222284B2 (es)
EP (1) EP2178508B1 (es)
JP (1) JP4875205B2 (es)
KR (1) KR101188036B1 (es)
CN (1) CN101730525A (es)
AR (1) AR067472A1 (es)
AU (1) AU2008275258A1 (es)
BR (1) BRPI0814039A2 (es)
CA (1) CA2694277C (es)
CL (1) CL2008001996A1 (es)
CO (1) CO6270304A2 (es)
CR (1) CR11210A (es)
DO (1) DOP2010000004A (es)
EA (1) EA016861B1 (es)
EC (1) ECSP109864A (es)
ES (1) ES2401477T3 (es)
GT (1) GT201000003A (es)
HK (1) HK1141238A1 (es)
IL (1) IL202382A0 (es)
MA (1) MA31880B1 (es)
MX (1) MX2010000468A (es)
NZ (1) NZ581791A (es)
PE (1) PE20090438A1 (es)
SV (1) SV2010003449A (es)
TN (1) TN2010000015A1 (es)
TW (1) TW200918050A (es)
UA (1) UA97672C2 (es)
WO (1) WO2009009470A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2447536B1 (en) 2009-06-26 2017-12-27 Mitsubishi Electric Corporation Refrigerant compressor

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1847534B9 (en) 2001-12-11 2012-03-21 Kyowa Hakko Kirin Co., Ltd. Thiadiazoline derivatives for treating cancer
EP1616866B1 (en) * 2003-04-18 2011-12-14 Kyowa Hakko Kirin Co., Ltd. M-stage kinesin inhibitor
JP2008150291A (ja) * 2005-03-22 2008-07-03 Kyowa Hakko Kogyo Co Ltd 乾癬治療剤
JPWO2006101103A1 (ja) * 2005-03-22 2008-09-04 協和醗酵工業株式会社 造血器腫瘍治療剤
KR20070113300A (ko) 2005-03-22 2007-11-28 교와 핫꼬 고교 가부시끼가이샤 고형종양 치료제
JP2008137893A (ja) * 2005-03-22 2008-06-19 Kyowa Hakko Kogyo Co Ltd 関節炎治療剤
JP2006265107A (ja) * 2005-03-22 2006-10-05 Kyowa Hakko Kogyo Co Ltd 緑内障治療剤
WO2006137490A1 (ja) * 2005-06-24 2006-12-28 Kyowa Hakko Kogyo Co., Ltd. 再狭窄治療剤

Also Published As

Publication number Publication date
US20110009458A1 (en) 2011-01-13
MX2010000468A (es) 2010-04-09
EP2178508A1 (en) 2010-04-28
TW200918050A (en) 2009-05-01
IL202382A0 (en) 2010-06-30
PE20090438A1 (es) 2009-04-18
CO6270304A2 (es) 2011-04-20
CN101730525A (zh) 2010-06-09
AU2008275258A1 (en) 2009-01-15
ES2401477T3 (es) 2013-04-19
KR101188036B1 (ko) 2012-10-05
EP2178508B1 (en) 2013-02-06
TN2010000015A1 (en) 2011-09-26
HK1141238A1 (en) 2010-11-05
UA97672C2 (ru) 2012-03-12
EA016861B1 (ru) 2012-08-30
CA2694277C (en) 2013-04-09
AR067472A1 (es) 2009-10-14
NZ581791A (en) 2012-03-30
US8222284B2 (en) 2012-07-17
KR20100029827A (ko) 2010-03-17
CL2008001996A1 (es) 2009-05-22
CA2694277A1 (en) 2009-01-15
CR11210A (es) 2010-06-23
MA31880B1 (fr) 2010-12-01
JP4875205B2 (ja) 2012-02-15
BRPI0814039A2 (pt) 2017-10-03
EA201070136A1 (ru) 2010-06-30
WO2009009470A1 (en) 2009-01-15
GT201000003A (es) 2012-03-13
JP2010533190A (ja) 2010-10-21
ECSP109864A (es) 2010-03-31
SV2010003449A (es) 2010-08-10

Similar Documents

Publication Publication Date Title
ECSP066715A (es)
BRPI0518904A2 (pt) formulaÇÕes de nepafenac tàpicas
UY28774A1 (es) Derivados de heteroarilaminopirazol utiles para el tratamiento de la diabetes.
NO20084853L (no) Forbindelser som er agonister av muscarinreseptorer og som kan vaere effektive i behandling av smerte, Alzheimers sykdom og/eller schizofreni
WO2009082152A3 (en) Glucokinase activators and pharmaceutical compositions containing the same as an active ingredient
UA110013C2 (uk) Застосування композиції для лікування шарко-марі-тута і пов'язаних з нею розладів
WO2006136580A3 (en) 2-(phenylamino)benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels
WO2008054698A3 (en) Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease
WO2006078576A3 (en) Aminomethyl beta-secretase inhibitors for the treatment of alzheimer's disease
WO2007058862A3 (en) Imidazolidinone compounds useful as beta-secretase inhibitors for the treatment of alzheimer's disease
WO2011023367A3 (en) Bisphosphonate-prodrugs
EP2142549A4 (en) ADENOSINE DERIVATIVES, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISEASES THEREOF CONTAINING THEM AS AN ACTIVE SUBSTANCE
WO2009105969A8 (zh) 埃坡霉素类似物、其药物组合物、用途及其制备方法
BRPI0920355B8 (pt) composições farmacêuticas tópicas estáveis de ozenoxacina e uso de ozenoxacina
WO2007090661A3 (en) Active substance combination comprising azolylcarbinol compounds
WO2009120389A8 (en) Oral and injectable formulations of tetracycline compounds
WO2007104485A3 (de) Substituierte imidazo[2,1-b]thiazol-verbindungen und ihre verwendung zur herstellung von arzneimitteln
WO2008033930A3 (en) Vinca derivatives
TW200800993A (en) Organic compounds
DOP2010000004A (es) Formulaciones estables de derivado de tiadiazol
IL194094A0 (en) Stable pharmacuetical compositions of 2-aza-bicyclol[3.3.0]-octane-3-carboxylic acid derivatives
BRPI0814500A2 (pt) Processo de fabricação de uma formulação contendo pelo menos um princípio ativo agroquímico, formulação, partículas sólidas e utilização de formulações aquosas, de dispersões aquosas de partículas sólidas e de partículas sólidas
WO2007047881A3 (en) Method for treating neuropathic pain
WO2010070057A3 (en) Precompacted fast-disintegrating formulations of compounds with a low oral bioavailability
WO2013124700A3 (en) Composition based on silybum marianum seed oil and process for the preparation of the seed oil