PE20061489A1 - Derivados de pirroliltriazina y procedimiento de preparacion - Google Patents

Derivados de pirroliltriazina y procedimiento de preparacion

Info

Publication number
PE20061489A1
PE20061489A1 PE2006000599A PE2006000599A PE20061489A1 PE 20061489 A1 PE20061489 A1 PE 20061489A1 PE 2006000599 A PE2006000599 A PE 2006000599A PE 2006000599 A PE2006000599 A PE 2006000599A PE 20061489 A1 PE20061489 A1 PE 20061489A1
Authority
PE
Peru
Prior art keywords
optionally substituted
alkyl
pyrrol
triazine
benzyl
Prior art date
Application number
PE2006000599A
Other languages
English (en)
Inventor
Cabanas Carles Trullas
Cabruja Carlos Pelejero
Arjona Jordi Corbera
Domenech David Vano
Jorg Holenz
Costa David Panyella
Original Assignee
Isdin Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isdin Sa filed Critical Isdin Sa
Publication of PE20061489A1 publication Critical patent/PE20061489A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4966—Triazines or their condensed derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

SE REFIERE A UN COMPUESTO DE FORMULA (I) DONDE n ES 0, 1, 2, 3 O 4; R1 ES H, ALQUILO(C1-C3), FENILO R2', R3' SUSTITUIDO; R2, R2', R3 Y R3' SON H, ALQUILO(C1-C3) OPCIONALMENTE SUSTITUIDO, ALCOXI(C1-C3), ENTRE OTROS; R4 Y R5 SON H, ALQUILO(C1-C4) O ARILO OPCIONALMENTE SUSTITUIDO; A1 ES UN COMPUESTO DE FORMULA (II), (IV), ENTRE OTROS; A2 ES UN COMPUESTO DE FORMULA (II) O (V), DONDE R6 ES H, ALQUILO(C1-C6) OPCIONALMENTE SUSTITUIDO U OH; R7 ES ARILO OPCIONALMENTE SUSTITUIDO, ALCOXI(C1-C18) OPCIONALMENTE SUSTITUIDO, CICLOALQUILO(C3-C6), ENTRE OTROS; R8 ES H, ACILO(C1-C18) OPCIONALMENTE SUSTITUIDO, ALQUILO(C1-C18) OPCIONALMENTE SUSTITUIDO CON OH, SO3M, ENTRE OTROS; R10 ES H O SO3M, DONDE M ES H, Na O K. SON COMPUESTOS PREFERIDOS: 2-(1-BENCIL-1H-PIRROL-2-IL)-4,6-BIS(2,4-DIHIDROXIFENIL)-1,3,5-TRIAZINA, 2-(1-BENCIL-1H-PIRROL-2-IL)- 4,6-BIS[4-(2-ETILHEXILOXI)-2-HIDROXIFENIL]-1,3,5-TRIAZINA, 2-(1-BENCIL-1H-PIRROL-2-IL)-4,6-BIS(BIFENIL-4-ILAMINO)-1,3,5-TRIAZINA, ENTRE OTROS. SE REFIERE TAMBIEN A UN PROCEDIMIENTO DE PREPARACION Y A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS ACTUAN COMO AGENTES PROTECTORES CONTRA LA RADIACION UV SIENDO UTILES EN LA PREVENCION Y TRATAMIENTO DE PATOLOGIAS CAUSADAS POR RADIACION ULTRAVIOLETA (UV)
PE2006000599A 2005-06-03 2006-06-02 Derivados de pirroliltriazina y procedimiento de preparacion PE20061489A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200501334A ES2272164B1 (es) 2005-06-03 2005-06-03 Nuevos derivados de pirroliltriazina asi como procedimientos para su obtencion y su utilizacion como agentes protectores contra la radiacionuv.

Publications (1)

Publication Number Publication Date
PE20061489A1 true PE20061489A1 (es) 2007-03-18

Family

ID=36688120

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2006000599A PE20061489A1 (es) 2005-06-03 2006-06-02 Derivados de pirroliltriazina y procedimiento de preparacion

Country Status (16)

Country Link
US (1) US20080253978A1 (es)
EP (1) EP1891050A1 (es)
JP (1) JP2008542341A (es)
KR (1) KR20080027286A (es)
CN (1) CN101189227A (es)
AR (1) AR058377A1 (es)
AU (1) AU2006254115A1 (es)
BR (1) BRPI0613545A2 (es)
CA (1) CA2611134A1 (es)
ES (1) ES2272164B1 (es)
IL (1) IL187385A0 (es)
MX (1) MX2007015130A (es)
PE (1) PE20061489A1 (es)
RU (1) RU2007148023A (es)
TW (1) TW200718696A (es)
WO (2) WO2006128791A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2931663B1 (fr) * 2008-05-30 2010-07-30 Galderma Res & Dev Nouvelles compositions depigmentantes anhydre comprenant un derive phenolique solubilise.
EP2153815A1 (en) 2008-08-05 2010-02-17 Isdin S.A. Use of urea containing compositions
EP2153814A1 (en) 2008-08-05 2010-02-17 Isdin S.A. Use of compositions comprising urea
EP2210887A1 (en) * 2009-01-14 2010-07-28 Isdin, S.A. Bis resorcinyl triazine derivatives as protecting agents against UV radiation
WO2013047411A1 (ja) * 2011-09-29 2013-04-04 富士フイルム株式会社 新規なトリアジン誘導体、紫外線吸収剤
JP5667955B2 (ja) * 2011-09-29 2015-02-12 富士フイルム株式会社 新規なトリアジン誘導体、紫外線吸収剤
DE102013215831A1 (de) * 2013-08-09 2015-02-12 Beiersdorf Ag Gelförmiges, alkoholisches Sonnenschutzmittel
DE102014203011A1 (de) * 2014-02-19 2015-08-20 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an einem oder mehreren Biphenylamin-Derivaten und Verwendung von einem oder mehreren Biphenylamin-Derivaten zur Bräunung der Haut

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3581002D1 (de) * 1984-06-22 1991-02-07 Ilford Ag Hydroxyphenyltriazine, verfahren zu ihrer herstellung und ihre verwendung als uv-absorber.
DE19543730A1 (de) * 1995-11-23 1997-05-28 Ciba Geigy Ag Bis-Resorcinyl-Triazine
US6090370A (en) * 1997-06-27 2000-07-18 Ciba Specialty Chemicals Corporation Use of selected benzotriazole and triazine derivatives for protecting human hair from the harmful effects of UV radiation
AU2003214092B2 (en) 2002-03-12 2008-05-15 Ciba Holding Inc. UV absorber compositions comprising a hydroxyphenyltriazine compound

Also Published As

Publication number Publication date
BRPI0613545A2 (pt) 2009-08-04
MX2007015130A (es) 2008-04-10
CN101189227A (zh) 2008-05-28
AR058377A1 (es) 2008-01-30
ES2272164A1 (es) 2007-04-16
ES2272164B1 (es) 2008-04-01
KR20080027286A (ko) 2008-03-26
US20080253978A1 (en) 2008-10-16
CA2611134A1 (en) 2006-12-07
WO2006128920A1 (en) 2006-12-07
AU2006254115A1 (en) 2006-12-07
IL187385A0 (en) 2008-02-09
TW200718696A (en) 2007-05-16
WO2006128791A1 (en) 2006-12-07
JP2008542341A (ja) 2008-11-27
EP1891050A1 (en) 2008-02-27
RU2007148023A (ru) 2009-07-20

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