PE20070177A1 - Derivados heptaazafenaleno como agentes contra la radiacion uv y su procedimiento de obtencion - Google Patents

Derivados heptaazafenaleno como agentes contra la radiacion uv y su procedimiento de obtencion

Info

Publication number
PE20070177A1
PE20070177A1 PE2006000826A PE2006000826A PE20070177A1 PE 20070177 A1 PE20070177 A1 PE 20070177A1 PE 2006000826 A PE2006000826 A PE 2006000826A PE 2006000826 A PE2006000826 A PE 2006000826A PE 20070177 A1 PE20070177 A1 PE 20070177A1
Authority
PE
Peru
Prior art keywords
radiation
derivatives
phenylamine
tris
heptaazaphenalene
Prior art date
Application number
PE2006000826A
Other languages
English (en)
Inventor
Cabanas Carles Trullas
Cabruja Carles Pelejero
Arjona Jordi Corbera
Jorg Holenz
Costa David Panyella
Original Assignee
Isdin Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isdin Sa filed Critical Isdin Sa
Publication of PE20070177A1 publication Critical patent/PE20070177A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE REFIERE A DERIVADOS DE HEPTAAZAFENALENO DE FORMULA (I), EN DONDE R1, R2, R3 SON INDEPENDIENTEMENTE ARILO MONO O POLICICLICO OPCIONALMENTE SUTITUIDO, HETEROCICLICO OPCIONALMENTE SUSTITUIDO DE 5 A 10 ATOMOS, OR4 O -NR5R6; R4 ES H, ALQUILO, CICLOALQUILO(C3-C12),ARILO,ENTRE OTROS; R5 Y R6 SON INDEPENDIENTEMENTE H, ALQUILO(C1-C18), ARILO, ENTRE OTROS. SON COMPUESTOS PREFERIDOS : 2,5,8-TRIS-(-4-(BUTOXICARBONIL)FENILAMINO)-1,3,4,6,7,9,9b-HEPTAAZFENALENO, 2,5,8-TRIS-(-4-(2-ETILHEXILOXICARBONIL)FENILAMINO)-1,3,4,6,7,9,9b-HEPTAAZAFENALENO, 2,5,8-TRIS-(-4-(IMIDAZOL[1,2-a]PIRIDIN-2-IL)-FENILAMINO)-1,3,4,6,7,9,9b-HEPTAAZAFENALENO, ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA Y UN PROCEDIMIENTO DE PREPARACION. ESTOS COMPUESTOS SON ABSORBENTES DE LA RADIACION UV (ULTRAVIOLETA) SIENDO EFECTIVOS EN LA LA PROTECCION CONTRA LA RADIACION UV-A Y UV-B POR LO QUE SON UTILES EN LA FABRICACION DE FORMULACIONES COSMETICAS, DERMATOLOGICAS VETERINARIAS Y FARMACEUTICAS QUE PROTEJAN LA PIEL, LABIOS, UNAS Y CABELLOS DE LA RADIACION UV
PE2006000826A 2005-07-13 2006-07-12 Derivados heptaazafenaleno como agentes contra la radiacion uv y su procedimiento de obtencion PE20070177A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200501746A ES2264904B1 (es) 2005-07-13 2005-07-13 Nuevos derivados de heptaazafenaleno, procedimientos para su obtencion, asi como utilizacion de estos como agentes protectores contra la radiacion uv.

Publications (1)

Publication Number Publication Date
PE20070177A1 true PE20070177A1 (es) 2007-04-14

Family

ID=37036766

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2006000826A PE20070177A1 (es) 2005-07-13 2006-07-12 Derivados heptaazafenaleno como agentes contra la radiacion uv y su procedimiento de obtencion

Country Status (19)

Country Link
US (1) US20080193398A1 (es)
EP (1) EP1904500A1 (es)
JP (1) JP2009501194A (es)
KR (1) KR20080031388A (es)
CN (1) CN101223174A (es)
AR (1) AR054831A1 (es)
AU (1) AU2006268582A1 (es)
BR (1) BRPI0613434A2 (es)
CA (1) CA2614582A1 (es)
ES (1) ES2264904B1 (es)
IL (1) IL188736A0 (es)
MX (1) MX2008000567A (es)
NZ (1) NZ565882A (es)
PE (1) PE20070177A1 (es)
RU (1) RU2008105077A (es)
TW (1) TW200740824A (es)
UY (1) UY29668A1 (es)
WO (1) WO2007006807A1 (es)
ZA (1) ZA200800252B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2008000096A1 (es) * 2007-01-12 2008-05-16 Isdin Combinacion farmaceutica que comprende dos compuestos uv-absorventes derivados de heptaazafenaleno; y su uso para tratar querotosis actinica, dermatitis, cronica, fotoenvejecimiento, urticaria solar, entre otras.
WO2008083975A1 (en) * 2007-01-12 2008-07-17 Isdin S.A. Light-stabilized composition
EP2153815A1 (en) 2008-08-05 2010-02-17 Isdin S.A. Use of urea containing compositions
EP2153814A1 (en) 2008-08-05 2010-02-17 Isdin S.A. Use of compositions comprising urea
DE102008045192A1 (de) * 2008-08-30 2010-03-04 Durferrit Gmbh Sprengstoff
DE102009009277B4 (de) * 2009-02-17 2023-12-07 Merck Patent Gmbh Organische elektronische Vorrichtung, Verfahren zu deren Herstellung und Verwendung von Verbindungen
US20120091884A1 (en) * 2009-05-22 2012-04-19 Commonwealth Scientific And Industrial Research Organisation Heptaazaphenalene derivatives and use thereof in organic electroluminescent device
US9985215B2 (en) 2012-03-09 2018-05-29 Kyulux, Inc. Light-emitting material, and organic light-emitting element
CN103755711B (zh) * 2013-12-23 2016-08-17 中节能万润股份有限公司 一种多氮杂环化合物及其制备方法和应用
KR101796391B1 (ko) * 2015-07-24 2017-11-09 동국대학교 산학협력단 Blt 저해 활성을 갖는 신규 화합물 및 이를 유효성분으로 포함하는 염증성 질환 예방 또는 치료용 조성물
CN106866683A (zh) * 2017-01-07 2017-06-20 青岛科技大学 一种溴代均草怕津的制备方法
JPWO2021256446A1 (es) * 2020-06-15 2021-12-23

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3089875A (en) * 1961-02-23 1963-05-14 Olin Mathieson Alkyl, aryl substituted melems
IT1283295B1 (it) * 1996-03-22 1998-04-16 3V Sigma Spa Filtri solari
EP0818450B1 (de) * 1996-07-08 2003-01-15 Ciba SC Holding AG Triazinderivate als UV-Filter in Sonnenschutzmitteln
EP0863145B1 (de) * 1997-03-03 2003-10-01 F. Hoffmann-La Roche Ag Lichtschutzmittel
US6090370A (en) * 1997-06-27 2000-07-18 Ciba Specialty Chemicals Corporation Use of selected benzotriazole and triazine derivatives for protecting human hair from the harmful effects of UV radiation

Also Published As

Publication number Publication date
JP2009501194A (ja) 2009-01-15
AU2006268582A1 (en) 2007-01-18
ES2264904B1 (es) 2007-12-01
BRPI0613434A2 (pt) 2011-01-11
KR20080031388A (ko) 2008-04-08
TW200740824A (en) 2007-11-01
WO2007006807A1 (en) 2007-01-18
CN101223174A (zh) 2008-07-16
AR054831A1 (es) 2007-07-18
IL188736A0 (en) 2008-08-07
US20080193398A1 (en) 2008-08-14
RU2008105077A (ru) 2009-08-20
UY29668A1 (es) 2007-01-31
EP1904500A1 (en) 2008-04-02
MX2008000567A (es) 2008-03-14
ZA200800252B (en) 2009-08-26
CA2614582A1 (en) 2007-01-18
ES2264904A1 (es) 2007-01-16
NZ565882A (en) 2011-03-31

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