PE20050760A1 - Formulacion farmaceutica de acido zoledronico y succinato de d-alfa tocoferil peg 1000 - Google Patents

Formulacion farmaceutica de acido zoledronico y succinato de d-alfa tocoferil peg 1000

Info

Publication number
PE20050760A1
PE20050760A1 PE2005000034A PE2005000034A PE20050760A1 PE 20050760 A1 PE20050760 A1 PE 20050760A1 PE 2005000034 A PE2005000034 A PE 2005000034A PE 2005000034 A PE2005000034 A PE 2005000034A PE 20050760 A1 PE20050760 A1 PE 20050760A1
Authority
PE
Peru
Prior art keywords
acid
succinate
peg
zoledronic acid
pharmaceutical formulation
Prior art date
Application number
PE2005000034A
Other languages
English (en)
Inventor
Erika Aina Zannou
Simon David Bateman
Madhusudhan Pudipeddi
Alan Edward Royce
Abu T M Serajuddin
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34738788&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20050760(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PE20050760A1 publication Critical patent/PE20050760A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: a) ACIDO BISFOSFONICO O UNA DE SUS SALES SELECCIONADAS DE IBANDRONATO, ALENDRONATO, ETIDRONATO, RISEDRONATO Y TILUDRONATO Y b) UN INGREDIENTE INACTIVO COMO ESTER DE UN ACIDO GRASO O UN ESTER DE POLIETILENGLICOL, MANTENIENDO UN BALANCE HIDROFILICO-LIPOFILICO (BHL) DE 1 A 30 COMO ACIDO CAPRILICO SELECCIONADO DE SUCCINATO DE D-ALFATOCOFERIL POLIETILENOGLICOL, ENTRE OTROS. EL ACIDO BISFOSFONICO SE SELECCIONA ADEMAS DEL ACIDO ZOLEDRONICO. LA FORMULACION COMPRENDE DE 0,01mg/kg A 500 mg/kg DE ACIDO BISFOSFONICO UTIL PARA EL TRATAMIENTO DE OSTEOPOROSIS
PE2005000034A 2003-12-23 2005-01-03 Formulacion farmaceutica de acido zoledronico y succinato de d-alfa tocoferil peg 1000 PE20050760A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53233403P 2003-12-23 2003-12-23

Publications (1)

Publication Number Publication Date
PE20050760A1 true PE20050760A1 (es) 2006-01-16

Family

ID=34738788

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2005000034A PE20050760A1 (es) 2003-12-23 2005-01-03 Formulacion farmaceutica de acido zoledronico y succinato de d-alfa tocoferil peg 1000

Country Status (13)

Country Link
US (1) US20070134319A1 (es)
EP (1) EP1699443A2 (es)
JP (1) JP2007516269A (es)
KR (1) KR20070012783A (es)
CN (1) CN1897926A (es)
AR (1) AR046773A1 (es)
AU (1) AU2004308644B2 (es)
BR (1) BRPI0418096A (es)
CA (1) CA2548363A1 (es)
PE (1) PE20050760A1 (es)
RU (1) RU2006126783A (es)
TW (1) TW200531696A (es)
WO (1) WO2005063218A2 (es)

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Also Published As

Publication number Publication date
KR20070012783A (ko) 2007-01-29
AU2004308644A1 (en) 2005-07-14
CN1897926A (zh) 2007-01-17
AU2004308644B2 (en) 2008-10-30
WO2005063218A3 (en) 2006-04-20
AR046773A1 (es) 2005-12-21
WO2005063218A2 (en) 2005-07-14
CA2548363A1 (en) 2005-07-14
US20070134319A1 (en) 2007-06-14
BRPI0418096A (pt) 2007-04-17
TW200531696A (en) 2005-10-01
EP1699443A2 (en) 2006-09-13
JP2007516269A (ja) 2007-06-21
RU2006126783A (ru) 2008-01-27

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