PE20030444A1 - Sales de acidos salicilicos y procedimientos para su preparacion - Google Patents

Sales de acidos salicilicos y procedimientos para su preparacion

Info

Publication number
PE20030444A1
PE20030444A1 PE2002000898A PE2002000898A PE20030444A1 PE 20030444 A1 PE20030444 A1 PE 20030444A1 PE 2002000898 A PE2002000898 A PE 2002000898A PE 2002000898 A PE2002000898 A PE 2002000898A PE 20030444 A1 PE20030444 A1 PE 20030444A1
Authority
PE
Peru
Prior art keywords
halogen
alkyl
alcoxy
preparation
salicylic acids
Prior art date
Application number
PE2002000898A
Other languages
English (en)
Inventor
Guenter Linz
Rainer Soyka
Andre Steiner
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2001145438 external-priority patent/DE10145438A1/de
Priority claimed from DE2002116125 external-priority patent/DE10216125A1/de
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of PE20030444A1 publication Critical patent/PE20030444A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • C07C217/10—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

SE REFIERE SALES DE ACIDO SALICILICO DE FORMULA I DONDE R1 Y R2 SON H, ALQUILO C1-C4, ALCOXI C1-C4, HALOGENO, COOH, OH, -COO-(ALQUILO C1-C4), ENTRE OTROS; R3 ES H, ALQUILO C1-C4, ALCOXI C1-C4, HALOGENO, -CF3, FENILO, PUDIENDO ESTAR EL ANILLO SUSTITUIDO POR UNO, DOS O TRES RADICALES SELECCIONADOS DEL GRUPO ALQUILO C1-C4, ALCOXI C1-C4, HALOGENO, -CF3 CON LA CONDICION DE QUE NO TODOS LOS RADICALES R1-R3 SON H, AL MISMO TIEMPO. SON COMPUESTOS PREFERIDOS SAL DE 3,5-DIISOPROPIL-SALICILATO DE 4-HIDROXI-O-[[[6-(4-FENILBUTOXI)-HEXIL]-AMINO]-METIL]-1,3-BENCENODIMETANOL, SAL DE 4-CLORO-SALICILATO DE 4-HIDROXI-O-[[[6-(4-FENILBUTOXI)-HEXIL]-AMINO]-METIL]-1,3-BENCENODIMETANOL, ENTRE OTROS. SE REFIERE TAMBIEN A UN PROCEDIMIENTO PARA LA PREPARACION DE ACIDOS SALICILICOS SUSTITUIDOS Y SALMETEROL. LOS COMPUESTOS MENCIONADOS SON UTILES EN EL TRATAMIENTO DE ASMA BRONQUIAL
PE2002000898A 2001-09-14 2002-09-12 Sales de acidos salicilicos y procedimientos para su preparacion PE20030444A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2001145438 DE10145438A1 (de) 2001-09-14 2001-09-14 Neue Arzneimittel zur Inhalation
DE2002116125 DE10216125A1 (de) 2002-04-12 2002-04-12 Salicylsäuresalze, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
PE20030444A1 true PE20030444A1 (es) 2003-07-03

Family

ID=26010150

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2002000898A PE20030444A1 (es) 2001-09-14 2002-09-12 Sales de acidos salicilicos y procedimientos para su preparacion

Country Status (7)

Country Link
EP (1) EP1429751A1 (es)
JP (1) JP4199114B2 (es)
CA (1) CA2460440A1 (es)
MX (1) MXPA04002400A (es)
PE (1) PE20030444A1 (es)
UY (1) UY27443A1 (es)
WO (1) WO2003024440A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012277403A1 (en) * 2011-06-30 2014-01-30 Ranbaxy Laboratories Limited Novel salts of sitagliptin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW6584A1 (en) * 1983-04-18 1985-04-17 Glaxo Group Ltd Phenethanolamine derivatives

Also Published As

Publication number Publication date
JP4199114B2 (ja) 2008-12-17
UY27443A1 (es) 2003-04-30
CA2460440A1 (en) 2003-03-27
WO2003024440A1 (de) 2003-03-27
MXPA04002400A (es) 2004-05-31
EP1429751A1 (de) 2004-06-23
JP2005504798A (ja) 2005-02-17

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal