PE20030436A1 - Preparacion solida que comprende benzimidazol - Google Patents

Preparacion solida que comprende benzimidazol

Info

Publication number
PE20030436A1
PE20030436A1 PE2002000828A PE2002000828A PE20030436A1 PE 20030436 A1 PE20030436 A1 PE 20030436A1 PE 2002000828 A PE2002000828 A PE 2002000828A PE 2002000828 A PE2002000828 A PE 2002000828A PE 20030436 A1 PE20030436 A1 PE 20030436A1
Authority
PE
Peru
Prior art keywords
preparation
active ingredient
inactivating
acid
benzimidazole
Prior art date
Application number
PE2002000828A
Other languages
English (en)
Inventor
Masae Sugaya
Toshihiro Shimizu
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of PE20030436A1 publication Critical patent/PE20030436A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2813—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA PREPARACION SOLIDA DESINTEGRABLE GASTRICA QUE COMPRENDE UN INGREDIENTE ACTIVO INACTIVADOR DEL ACIDO Y POR LO MENOS UN OXIDO DE METAL E HIDROXIDOS DE METAL. LA PREPARACION NO POSEE RECUBRIMIENTO ENTERICO Y TIENE UN TIEMPO DE DESINTEGRACION DE 7 MINUTOS O MENOS ASIMISMO COMPRENDE UN COMPONENTE ADICIONAL SELECCIONADO DE CARBONATOS DE METAL ALCALINO TERREO Y ADITIVOS BASICOS QUE POSEEN UNA ELEVADA SOLUBILIDAD EN AGUA. EL INGREDIENTE INACTIVADOR DEL ACIDO ES UNA INHIBIDOR DE BOMBA DE PROTON PPI BENZIMIDAZOL DE FORMULA I COMO LANSOPRAZOL, OMEPRAZOL, RABEPRAZOL, PANTOPRAZOL DONDE A ES UN ANILLO BENCENO; R1 ES H, ARALQUILO, ACILO, ACILOXILO; R2, R3, R4 SON H, ALQUILO, ALCOXILO ENTRE OTROS. LA PREPARACION TIENE UNA ACCION ANTIULCEROSA Y PUEDE NEUTRALIZAR RAPIDAMENTE EL EFECTO FARMACOLOGICO DEL INGREDIENTE ACTIVO Y SUPRIME LA GENERACION DE GAS ANHIDRIDO CARBONICO
PE2002000828A 2001-08-31 2002-08-28 Preparacion solida que comprende benzimidazol PE20030436A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001263481 2001-08-31
JP2001341477 2001-11-07
JP2002060006 2002-03-06

Publications (1)

Publication Number Publication Date
PE20030436A1 true PE20030436A1 (es) 2003-07-04

Family

ID=27347410

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2002000828A PE20030436A1 (es) 2001-08-31 2002-08-28 Preparacion solida que comprende benzimidazol

Country Status (6)

Country Link
US (1) US20040248939A1 (es)
EP (1) EP1420763A1 (es)
AR (1) AR036354A1 (es)
CA (1) CA2448760A1 (es)
PE (1) PE20030436A1 (es)
WO (1) WO2003017980A1 (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
ES2348710T5 (es) 2001-06-01 2014-02-17 Pozen, Inc. Composiciones farmacéuticas para el suministro coordinado de NSAID
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
US8697094B2 (en) 2002-10-16 2014-04-15 Takeda Pharmaceutical Company Limited Stable solid preparations
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
ES2283172B1 (es) * 2005-01-21 2008-08-16 Universidad De Granada Suspension extemporanea de omeprazol para via oral.
US20070020334A1 (en) * 2005-07-11 2007-01-25 Poul Bertelsen Benzimidazole formulation
WO2006105798A2 (en) * 2005-07-11 2006-10-12 Nycomed Danmark Aps Benzimidazole formulation
WO2007041790A1 (en) * 2005-10-14 2007-04-19 Jon Pty Limited Salts of proton pump inhibitors and process for preparing same
MY151470A (en) * 2005-12-28 2014-05-30 Takeda Pharmaceutical Controlled release solid preparation
SG184754A1 (en) * 2005-12-28 2012-10-30 Takeda Pharmaceutical Controlled release solid preparation
MY157620A (en) 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
WO2008057802A2 (en) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
GB0714670D0 (en) 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
GB0720220D0 (en) 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
CN101980700A (zh) 2008-02-20 2011-02-23 密苏里大学董事会 包含奥美拉唑和兰索拉唑以及缓冲剂的组合的组合物及其使用方法
CA2736547C (en) 2008-09-09 2016-11-01 Pozen Inc. Method for delivering a pharmaceutical composition to patient in need thereof
AU2010263304A1 (en) 2009-06-25 2012-02-02 Astrazeneca Ab Method for treating a patient at risk for developing an NSAID-associated ulcer
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
UA115139C2 (uk) 2011-12-28 2017-09-25 Поузен Інк. Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту
KR101841662B1 (ko) * 2016-06-02 2018-03-23 동화약품주식회사 프로톤 펌프 저해제의 고체분산체 및 이를 포함하는 약제학적 조성물
MX2022004464A (es) * 2019-10-17 2022-05-03 Hanmi Pharm Ind Co Ltd Composicion farmaceutica que comprende un inhibidor de la bomba de protones y un antiacido.
EP4023216A4 (en) * 2019-10-17 2023-05-10 Hanmi Pharm. Co., Ltd. PHARMACEUTICAL COMPOSITION WITH PROTON PUMP INHIBITOR AND ANTACID
WO2021150050A1 (ko) * 2020-01-23 2021-07-29 한미약품 주식회사 프로톤 펌프 저해제 및 제산제를 포함하는 약제학적 복합제제
CN111281855B (zh) * 2020-03-23 2021-09-24 乐普制药科技有限公司 一种雷贝拉唑肠溶片及其制备方法
KR102608889B1 (ko) * 2020-07-14 2023-12-04 한미약품 주식회사 프로톤 펌프 저해제 및 제산제를 포함하는 약제학적 복합제제 및 그의 제조방법
CN113384547B (zh) * 2021-06-25 2024-03-19 上海信谊万象药业股份有限公司 一种奥美拉唑铝碳酸镁复合片及其制备工艺

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3316703A1 (de) * 1983-05-04 1984-11-08 Schering AG, 1000 Berlin und 4709 Bergkamen Orales kontrastmittel fuer die kernspintomographie und dessen herstellung
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) * 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9600071D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients I
US6235311B1 (en) * 1998-03-18 2001-05-22 Bristol-Myers Squibb Company Pharmaceutical composition containing a combination of a statin and aspirin and method
JP4127740B2 (ja) * 1998-04-20 2008-07-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 安定化したベンズイミダゾール系化合物含有組成物
KR100627614B1 (ko) * 1998-04-20 2006-09-25 에자이 가부시키가이샤 안정화된 벤즈이미다졸계 화합물 함유 조성물로 이루어지는 의약제제
ATE369857T1 (de) * 1999-10-20 2007-09-15 Eisai R&D Man Co Ltd Methode zur stabilisierung von benzimidazol- verbindungen

Also Published As

Publication number Publication date
AR036354A1 (es) 2004-09-01
CA2448760A1 (en) 2003-03-06
WO2003017980A1 (en) 2003-03-06
EP1420763A1 (en) 2004-05-26
US20040248939A1 (en) 2004-12-09

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