PE20020265A1 - Combinaciones de carboxialquileter - inhibidor de acat - Google Patents
Combinaciones de carboxialquileter - inhibidor de acatInfo
- Publication number
- PE20020265A1 PE20020265A1 PE2001000517A PE2001000517A PE20020265A1 PE 20020265 A1 PE20020265 A1 PE 20020265A1 PE 2001000517 A PE2001000517 A PE 2001000517A PE 2001000517 A PE2001000517 A PE 2001000517A PE 20020265 A1 PE20020265 A1 PE 20020265A1
- Authority
- PE
- Peru
- Prior art keywords
- alkyl
- phenyl
- cholesterol
- carboxialkyleter
- cycloalkyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A UNA COMPOSICION QUE COMPRENDE a)UN CARBOXIALQUILETER DE FORMULA ( Y1)(R1)(R2)C-(CH2)n-O-(CH2)m-C(Y2)(R3)(R4) DONDE, n Y m SON 2-9; R1, R2, R3, R4 SON ALQUILO C1-C6, ALQUENILO C1-C6, ALQUINILO C1-C6, R1 Y R2 O R3 Y R4 JUNTOS FORMAN CARBOCICLO C3-C6; Y1 E Y2 SON COOH, CHO, TETRAZOL, COOR5; R5 ES ALQUILO C1-C5, ALQUENILO C2-C6, ALQUINILO C2-C6; b)UN INHIBIDOR DE LA ENZIMA ACETIL-COENZIMA A:COLESTEROL ACILTRANSFERASA (ACAT) QUE PREVIENE LA ABSORCION DEL COLESTEROL DIETARIO EN EL FLUJO SANGUINEO O LA REABSORCION DE COLESTEROL QUE PREVIAMENTE HA SIDO LIBERADO EN EL INTESTINO A TRAVES DE LA PROPIA ACCION REGULADORA DEL CUERPO; DE FORMULA R1-X-S(=O)2-NR-C(=O)-Y-R2; DONDE X E Y SON S, O; (CR'R")n; n ES 1-4; R' Y R" SON H, ALQUILO, ALCOXI, HALOGENO, OH, ACILOXI, CICLOALQUILO, FENILO R' Y R" FORMAN ESPIROCICLOALQUILO, CARBONILO; UNO DE X E Y ES (CR'R")n; Y R' Y R" SON H; n ES 1; R1 Y R2 SON ARILO; R ES H, ALQUILO C1-C8, BENCILO; R1 Y R2 SON FENILO, FENOXI, NAFTILO, ARILALQUILO, ALQUILO C1-C20, ADAMANTILO, CICLOALQUILO C3-C6; SIENDO COMPUESTOS PREFERIDOS 2,6-DIISOPROPIL-FENIL ESTER DEL ACIDO [(2,4,6-TRIISOPROPIL-FENIL)-ACETIL]SULFAMICO, ACIDO 6,6'-OXIBIS(2,2-DIMETILHEXANOICO). LA COMPOSICION PUEDE SER UTIL PARA LOGRAR UN EFECTO DE DISLIPIDEMIA MEJORADA Y UN EFECTO DE SINDROME ISQUEMICO MEJORADO
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21005600P | 2000-06-07 | 2000-06-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20020265A1 true PE20020265A1 (es) | 2002-04-19 |
Family
ID=22781424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001000517A PE20020265A1 (es) | 2000-06-07 | 2001-06-05 | Combinaciones de carboxialquileter - inhibidor de acat |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1292363A2 (es) |
| JP (1) | JP2003535125A (es) |
| AR (1) | AR034255A1 (es) |
| AU (1) | AU2001263003A1 (es) |
| BR (1) | BR0111428A (es) |
| CA (1) | CA2413906A1 (es) |
| GT (1) | GT200100106A (es) |
| MX (1) | MXPA02010762A (es) |
| PA (1) | PA8518601A1 (es) |
| PE (1) | PE20020265A1 (es) |
| SV (1) | SV2002000466A (es) |
| TN (1) | TNSN01085A1 (es) |
| UY (1) | UY26752A1 (es) |
| WO (1) | WO2001093845A2 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7387236B2 (en) | 2001-10-09 | 2008-06-17 | Delaware Capital Formation, Inc. | Dispensing of currency |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999038498A1 (en) * | 1998-01-28 | 1999-08-05 | Warner-Lambert Company | Method for treating alzheimer's disease |
-
2001
- 2001-05-08 CA CA002413906A patent/CA2413906A1/en not_active Abandoned
- 2001-05-08 AU AU2001263003A patent/AU2001263003A1/en not_active Abandoned
- 2001-05-08 JP JP2002501418A patent/JP2003535125A/ja active Pending
- 2001-05-08 MX MXPA02010762A patent/MXPA02010762A/es not_active Application Discontinuation
- 2001-05-08 WO PCT/US2001/014804 patent/WO2001093845A2/en active Application Filing
- 2001-05-08 EP EP01937250A patent/EP1292363A2/en not_active Withdrawn
- 2001-05-08 BR BR0111428-0A patent/BR0111428A/pt not_active IP Right Cessation
- 2001-05-24 SV SV2001000466A patent/SV2002000466A/es not_active Application Discontinuation
- 2001-06-05 TN TNTNSN01085A patent/TNSN01085A1/en unknown
- 2001-06-05 UY UY26752A patent/UY26752A1/es not_active Application Discontinuation
- 2001-06-05 GT GT200100106A patent/GT200100106A/es unknown
- 2001-06-05 PA PA20018518601A patent/PA8518601A1/es unknown
- 2001-06-05 PE PE2001000517A patent/PE20020265A1/es not_active Application Discontinuation
- 2001-06-06 AR ARP010102688A patent/AR034255A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SV2002000466A (es) | 2002-04-03 |
| WO2001093845A2 (en) | 2001-12-13 |
| WO2001093845A3 (en) | 2002-10-10 |
| EP1292363A2 (en) | 2003-03-19 |
| AU2001263003A1 (en) | 2001-12-17 |
| MXPA02010762A (es) | 2003-03-10 |
| AR034255A1 (es) | 2004-02-18 |
| CA2413906A1 (en) | 2001-12-13 |
| UY26752A1 (es) | 2001-07-31 |
| GT200100106A (es) | 2002-05-20 |
| BR0111428A (pt) | 2003-06-10 |
| PA8518601A1 (es) | 2002-07-30 |
| JP2003535125A (ja) | 2003-11-25 |
| TNSN01085A1 (en) | 2005-11-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ECSP045331A (es) | Forma de presentación para administración por vía oral, para éster etílico de ácido 3?[(2-{[4-(hexiloxicarbonilamino-imino-metil)-fenilamino]-metil}-1-metil-1H-?bencimidazol-5-carbonil)-piridin-2-il-amino]-propiónico y sus sales | |
| DK0788350T3 (da) | Dannelse af små partikler | |
| DK1397130T3 (da) | Substituerede indolsyrederivater som inhibitorer af plasminogenaktivatorinhibitor-1 (PAI-1) | |
| HUP9701540A1 (hu) | A gasztrointesztinális keringést elősegítő gyógyászati készítmény | |
| SE0400235D0 (sv) | New composition containing quinoline compounds | |
| PT998473E (pt) | Modificacao da forma de cristal de um derivado de n-fenil-2-pirimidinoamina processos para a sua preparacao e sua utilizacao | |
| PE20091682A1 (es) | Compuestos de carbamoilo como inhibidores de dgat1 190 | |
| JP2009522292A5 (es) | ||
| BR0316586A (pt) | Derivados de diidropirano indol-3, 4-dione e derivados de 3-ácido oxoacético 2-hidroximetilindol substituìdo como inibidores do inibidor-1 do ativador do plasminogênio (pai-1) | |
| HUP0002514A2 (hu) | [5-Aril-2-(aril-amino)-fenil]-ecetsavak és származékaik | |
| NZ592224A (en) | Acrylamido derivatives useful as inhibitors of the mitochondrial permeability transition | |
| PE20051160A1 (es) | DERIVADOS DE BETA-AMINOACIDOS COMO INHIBIDORES DEL FACTOR Xa | |
| NO20051011L (no) | Kirale oksazol-arylpropionsyrederivater og anvendelse derav som PPAR agonister | |
| WO2010132815A1 (en) | Curcumin analogues as zinc chelators and their uses | |
| PE20020265A1 (es) | Combinaciones de carboxialquileter - inhibidor de acat | |
| EP2597083A3 (en) | Selective hydroxamate based MMP inhibitors | |
| BRPI0811245A2 (pt) | Composto de carbamoilóxi-aril-alcanoil-aril-piperazinas, composições farmacêuticas que compreendem o composto, e método para tratar dor, ansiedade e depressão administrando o composto. | |
| CA2038409C (en) | Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase | |
| PE47596A1 (es) | Derivado de quinoxalina util en terapia | |
| PE20011308A1 (es) | Composicion que comprende un antihipertensivo y un carboxialquileter util para tratar enfermedades vasculares | |
| ES2143206T3 (es) | Procedimiento para la produccion de acido lipoico. | |
| NO994386L (no) | 2-substituerte benzoylcykloalkyl-1-karboksylsyrederivater | |
| DE602004013658D1 (de) | Kupplersubstanzen mit 2,3,5-Triaminopyridin-Struktur und deren Verwendung zum Färben von Keratinfasern | |
| FR2726558B1 (fr) | Nouvelles 5-(aryloxymethyl) oxazolines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
| DE602004004810D1 (de) | Herstellungsverfahren für optisch reine 2-(4-hydroxyphenoxy)-propionsäureverbindungen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |